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      • KCI등재후보

        열공성 뇌경색과 뇌내출혈의 위험인자 비교

        이장준,이현아,최종환,이형,임정근,이상도,박영춘 계명대학교 의과학연구소 2000 계명의대학술지 Vol.19 No.2

        Cerebral small vessel disease is the most important cause of lacunar infarction (LI) and intracerebral hemorrhage (ICH). It is generally postulated that, in its early stages, the vascular lesion engenders vessel wall fragility and ICH. But if rupture dose not occur, segmental vessel occlusion evolves, producing LI. It may be a common aging phenomenon that is exacerbated by hypertension and diabetes mellitus. This study was performed to evaluate risk factors of LI and ICH. We reviewed retrospectively the medical records of 690 patients (254 LI, 436 ICH) with stroke who were admitted to Keimyung University Dongsan Medical Center from January 1995 to December 1998. The major risk factors including age, sex, hypertension, diabetes mellitus and several minor risk factors were analyzed in these patients. Older age (p<0.01), male sex(p<0.01), hypertension with treatment(p<0.01), hypertension with long duration(p<0.01) and hypertriglyceridemia(p<0.01), cigarette smoking(p<0.01) were significantly more frequent in LI. Younger age(p<0.01), female sex(p<0.01) and hypertension without treatment(p<0.01), hypertension with short duration(p<0.01) were more frequent in ICH. The prevalence, duration and treatment of diabetes mellitus were not different between these two groups. This study show that the age, sex, treatment of hypertension, duration of hypertension and cigarette smoking seem to be significant risk factors between LI and ICH.

      • 만성 호중구성 백혈병 1례

        기장도,박치영,류보열,김태종,모성환,곽재정,문철호,박근홍,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.1

        Chronic neutrophilic leukemia is a very rare myeloproliferative disorder which is characterized by severe sustained mature neutrophilic leukocytosis in peripheral blood (PB), hepatosplenomegaly, elevated leukocyte alkaline phosphatase, serum uric acid. serun viatmin B 12 and the bleeding tendency despite normal platelet count and coagulation time, absence of philadelphia chromosome, and the absence of fever or underlying infection or disease sufficient to mimic a leukemoid reaction. We have experienced a 34-years-old male patient with atypical chronic neutrophilic leukemia. On admission, the leukocyte count was 56,860/uL. severe neutrophic leukocytosis with 76% neutrophils and rare immature forms on PB smear. Many neutrophils had toxic granules, and vacuoloes. Leukocyte alkaline phosphatase score was decreased. The cytogenetic study showed Philadelphia chromosome negative with normal karyotype.

      • 海洋微生物에 의한 高濃度鹽分含有 廢水處理의 基礎硏究 (Ⅰ)

        尹星閏,河淸根,李泰永,張哲鉉,朴勝祚 동아대학교 환경문제연구소 1989 硏究報告 Vol.12 No.1

        This study considered organic matter decomposition by ocenic microbes as researching organic matter decomposition on kinetics which is in salinity wastewater under condition that the salinity contains 18,000㎎/l Cℓ^(-) The results of this study are obtained as following : 1. Oceanic microbe of this study is yeast, R. glutinis var. salinaria of marina of Rhodotorula genuses. 2. When retention time of filter bed in Bio-coal tower is 24 hr, 1/2V_(max) is 33.75㎎/l·hr, When 72hr, 1/2V_(max) is 15㎎/l·hr, When 120hr, 1/2V_(max) is 10㎎/l·hr. 3. The reaction between oceanic microbes and organic matter is said to be first order and when contact time of filter bed is 2.0hr, k is 0.40 day^(-1).

      • KCI등재후보

        내측 측두엽 간질에서 간질발작 중 언어증상

        이장준,이승환,이형,김지언,임정근,손은익,이상도,박영춘 계명대학교 의과학연구소 2000 계명의대학술지 Vol.19 No.1

        Background and Objectives : Several speech manifestation are observed in temporal lobe epilepsy(TLE). We studied the frequency of ictal speech manifestations and their localizing and lateralizing value in TLE. Methods : We reviewed 379 seizures recorded on videotape in 135 patients who underwent temporal lobectomy for intractable TLE. We divided patients into group A(n=75) who became seizures free after surgery, and group B(n=60) who were only slightly benefited or unchanged after surgery. Speech manifestations were classified as normal speech, vocalization, or abnormal speech. Abnormal speech was subdivided into speech arrest, dysarthria, dysphasia, or nonidentifiable speech. Results : Speech manifestations occurred in 70(18.5%) seizures of 28 patients. Forty eight seizures of 20 patients were observed in group A, and 22 seizures of 8 patients were observed in group B. In group A, 25 seizures of 11 patients were originating from dominant hemisphere, 23 seizures of 9 patients from nondominant hemisphere. In group B, 13 seizures of 5 patients were originating from dominant hemisphere, and 9 seizures in Lt. side and 6 seizures in Rt. side, respectively) of group A(P>0.05), and eleven seizures of 4 patients(8 seizures from Lt. side and 3 seizure from Rt. side) in group B(P>0.05). Normal speech was observed only seizures from Rt. side in both groups(3 seizures in 1 patient, each group). Dysphasia occurred only in seizures originating from Lt. side. Nonidentifiable speech occurred in 22 seizures of 9 patients(11 seizures from each side) in group A(P<0.01), and 3 seizures of 1 patient occurred only from Lt. side in group B. Conclusion : Ictal speech manifestations were not uncommon(18.5%). All kinds of ictal speech manifestations except normal speech have no reliable lateralizing and localizing value in TLE. Normal speech could be a good indicator of seizure originating from nondominant hemisphere.

      • 함마의 재질이 규석의 분쇄에 미치는 영향

        이재장,장상건,장광택,박종력 江原大學校 産業技術硏究所 2002 産業技術硏究 Vol.22 No.A

        In Kwangjin industrial company, mill is operating for the foundry sand production at the rate of 25t/hr from quartzite. Foundry sands fall into four distinct categories: silica sand, lake sand, bank sand, and natural molding sand. Silica sand is a general term used to describe crushed, washed, graded, dried, and cooled clay-free sands. This study was conducted for the investigation of the foundry sand productivity and the life span of the hammer according to the material quality. The life time of hammer from several manufacturer were compared in order to find out the grinding efficiency of the various hammer material. In the result of tests, the life time of high-Mn hammer was 10.5 hours while that of high-Cr was 19.5 hours. The life time in case of typical worn shape hammers was about 12 hours and the average time of a blowhole hammer was about 6.5 hours.

      • 흡착공정에서 압력평등화 단계에 관한 연구

        徐成燮,張東根 弘益大學校 科學技術硏究所 1997 科學技術硏究論文集 Vol.8 No.-

        One of the simple multibed PSA processes is a three-bed adsorption process which simultaneously includes pressure equalization step, pressurization step using high-pressure product, production step, blowdown step, and a purge step in a cyclic state. Pressure equalization step reduces the loss of feed gas component arising from the depressurization and desorption. In this study, pressure equalization step was studied for local equilibrium model for the separation of hydrogen and carbon dioxide on the molecular sieve 5A and activated carbon. Pressure equalization level after the pressure equalization step was continuously increased as increase of the initial pressure ratio of the two beds. The results of this study would be useful in predicting and calculating the pressure equalization level using different models concerning the transfer phenomena.

      • 휴대전화의 전자파가 생쥐의 뇌에서 p39의 발현에 미치는 영향

        정기윤,김경훈,장성근 순천향대학교 기초과학연구소 2004 순천향자연과학연구 논문집 Vol.10 No.2

        p39 is a regularory subunit of Cdk5(Cyclin-dependent kinase 5) that regulate cell division. Reletive quantitation of p39 RNA has done by Q-RT PCR method. ICR female mice are exposed at electromagnetic wave making machine simulated as korean standard cellular phone wave frequency and wave length for 9 hours/day for 3 months before sacrificed. Brain regions are removed from sliced brain tissue in 400um thick. Total cellular RNA was extracted from cerebellum, hippocampus, thalamus and hypothalamus for Q-RT PCR process using SYBR green dye. In cerebellum, p39 expression level is decreased at 1/5 of the control. In thalamus and hypothalamus, the level is decreased at half of the control. But in hippocampus the expression level of the p39 is not changed. Differential effect of the cellular phone like electromagnetic wave to verious region of the brain is examined.

      • 거골 골절의 수술적 치료

        최호림,이장근,최훈휘,최성우 대한골절학회 2003 대한골절학회지 Vol.16 No.1

        목 적 : 거골 골절 수술적 치료 후 임상 결과를 분석하여 얻은 결과를 보고하며 향후 적절한 치료 방침을 결정하는데 도움이 되고자 한다. 대상 및 방법 : 1990년 3월부터 2000년 11월까지 본원에서 거골 골절로 치료한 환자 60례중 수술적 치료후 1년 이상 추시가 가능하였던 34례의 수술 전,후 및 추시 방사선 사진과 의무 기록지를 후향적으로 분석하였으며 현 환자의 상태는 외래 진료를 통한 직접 면담이나, 서면 또는 전화를 이용한 질문표에 대한 답변 등을 이용하여 분석하였다. 임상 결과의 판정은, 동통과 파행, 거골하 관절 및 족근 관절에서의 운동 범위등, 네 가지 요소에 따라 판정하는 Hawkins 평가 방법을 이용하였다. 결 과 : 총 34례중 25례(74%)에서 양호 이상의 만족스러운 임상 결과를 보였으나, 분쇄 정도가 심하여 조기에 정확한 해부학적 정복을 얻지 못했거나 주위 조직의 심한 손상 또는 타과적 손상이 동반되어 치료가 지연된 경우에서는 만족스럽지 못하였다. 무혈성 괴사는 Hawkins 징후가 보이지 않았던 8레중 6례에서 발생하였으며, 보존적 치료를 시행하여 만족할만한 임상 결과를 얻을 수 있었다. 결론 : 거골 경부 골절 치료후 임상 결과는 가능한 조기의 관혈적 정복을 통한 정확한 해부학적 정복 및 내고정이 무엇보다 중요하다고 생각되며, 더불어 적극적인 재활치료의 여부도 예우에 큰 영향을 줄 수 있다. 수술적 도달법에 의한 차이나 사용된 내고정물에 의한 임상 결과의 차이는 보이지 않았다. 무혈성 괴사 유무와 임상 결과는 반드시 일치하는 것은 아니었다. Purpose : To evaluate the clinical results and develop guidelines for surgical treatment of talus fracture. Materials and Methods : Among the 60 cases that were treated during March 1990 to November 2000, 34 cases were treated operatively and followed up for more than one year( range : 1~4.4 years). They were analyzed retrospectively with questionnaire directly or by telephone interview, radiograms and medical records. Clinical results were evaluated by Hawkins' scoring system. Results : 25 out of 34 cases showed satisfactory results. Unisatisfactory results were seen in cases that we couldn't achieve anatomical reduction due to severe communication, and also in case of delayed treatment due to severe communition, and also in case of delayed treatment due to associated trauma and soft tissue injury. Six out of 8 cases that showed no Hawkins' sign developed avascular necrosis. However, satisfactory results were achieved through conservative treatment. Conclusion : Satisfactory results could be achieved through early anatomical reduction and rigid internal fixation followed by aggressive rehabilitation. There was no differences in clinical results either by the surgical approach or method of internal fixation. Avascular necrosis was not essentially related to the clinical results.

      • 수평횡파형 유도초음파 산란에 대한 혼합형 경계요소 모델링

        조윤호,이준현,Rose, J. L.,정상훈,장영익,이원근 한국비파괴검사학회 2004 학술대회 논문집 Vol.- No.-

        Overlap에서의 유도 초음파 산란에 대한 정량적인 예측을 가능하게 하고 유도 초음파를 이용한 효율적인 NDE가 overlap 구조물들에서 수행되어지기 위해서 혼합형 경계요소법을 이용하였다. 다양한 joint를 가진 다층 구조물에서 적절한 모드를 선택하고 주파수를 조정함으로써 수행되어졌다. 두께의 차이에 의한 전달과 반사의 값들의 변화를 살펴보고 정해진 형상에서의 주파수 증가와 다수의 파동을 포함한 긴 overlap 길이를 가진 모델에 대한 산란 선도의 변동을 보여주게 된다.

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