발모제가 발모효과에 미치는 영향에 관한 연구

최경임,이진태,안봉전,최은영,박찬익 경산대학교 생명자원개발연구소 2002 생명자원과 산업 Vol.6 No.-

지금까지의 발모관리는 의학적인 차원에서 원형탈모, 남성형 탈모증 및 약제에 의한 병리학적인 연구가 있었으나 미용적인 관리에 대한 연구가 거의 없었다. 따라서 본 논문에서는 약품을 사용하지 않고 순수한 발모촉진 화장품과 두피관리 프로그램을 중심으로 발모관리를 통해 탈모개선 효과를 비교검토하였다. 탈모자를 여러 그룹으로 선발하고 발모제를 달리 처방하여 모발의 굵기, SEM 촬영, 수분측정, 정상인의 모발상태와 탈모자의 모발상태를 TEM 촬영하여 비교 분석하였다. 먼저 두피관리 전과 후의 수분함량의 차이는 평균 16% 상승하였다. 발두께 비교실험에서는 정상모에 비해 탈모자의 모발이 최대 38.6%가 작은 것으로 나타났으며, 모유두와 모간의 촬영사진에서는 탈모자의 모유두는 덜 발달되어 있었고, 변형된 모유두 형태가 많았다. 전자현미경을 통한 모표피의 SEM촬영에서는 탈모자나 정상모나 표면적으로 큰 차이는 없었다. 오히려 탈모자의 경우에는 모발이 약하고 건강하지 못하기 때문에 화학적인 처방을 하는 염색이나 펌 등을 하지 않아서 모발의 큐티클 층은 정상인의 모발보다 건강한 상태로 보였다. 두피측정에서는 관리 후 A, B, C 군의 비교에서 세 그룹 모두 두피의 현저한 개선효과를 보였다. 육모제를 사용한 A, B, Group과 영양제를 사용하지 않고 스캘링과 관리를 한 C군 모두 발모효과가 있었으며, 두피관리를 전혀 하지 않는 D군은 발모효과나 두피의 개선효과는 전혀 없었다. 전자 현미경을 통한 모발의 단면 촬영에서는 정상모발이 탈모자의 모발보다 피질이 부드럽고 풍성하게 잘 형성되어 있었다. 탈모자의 경우는 매우 심각한 고민거리인데 본 실험의 결과 가장 효과적인 발모 관리는 육모제로 두피의 혈액순환을 도와주고 평소생활에서 Brushing으로 모공이 막히지 않도록 꾸준한 손질을 함으로써 발모 및 두피개선이 될 수 있다는 것을 확인할 수 있었다. Twenty working people from 30s to 50s whose hairs were in the process of losing were selected for this study. They were divided into four groups as A, B, C and D. Their hairs were sampled to compare the thickness of the hairs through a optical microscope. Using hair care products from two marketing companies, once a week, Group A and B were treated scalp scaling and steam treatment during ten minutes. After applying vitamin cream the scalp was examined using a bio-beam every 5 minutes. Group C did not receive any vitamin cream but had the same treatment as A and B. Group D used no vitamin cream and receives no treatment. The results were as follows: In Comparison losing hair surface with healthy hair surface by electronic microscope, losing hair took place when the scalp has keratin or too much fat. After comparing the amount of moisture before and after care by a moisture measurement instrument, the amount of moisture has been outstandingly increased. As a result of observing hair root and hair shaft, hair root appeared to be less developed than healthy hair. These results showed that hair care is need to be constantly research and illuminate with regard to the proper care.

카드뮴 정맥주사시 랏트의 치사율과 간, 신에서의 양-반응관계

김인봉,박정덕,홍연표,장임원 중앙대학교 의과대학 의과학연구소 1992 中央醫大誌 Vol.17 No.4

To investigate the lethality and dose-response relationship in liver and kidney of rats at 48 hours after cadmium exposure, single doses of cadmium chloride were given to Sprague-Dawley male rats by tail-intravenous injection with several groups of doses ranging from 2 to 8 mg CdCl_2/kg for lethality and from 0.2 to 3.2 mg CdCl_2/kg for dose-response relationship. In addition, control was treated with distilled water by same method. Hepatic and renal cadmium concentrations were analyzed with I.C.P.(Inductively Coupled Plasm) Emission Spectrometry (Jobin Yvon, Model JY 24, France). Dosages over 4 mg/kg were relevant to LD_100 and LD_50 was calculated as 3.3 mg/kg at 48 hours after cadmium chloride exposure in rat. The concentration in liver and kidney were increased according to given doses, and dose-response relationship was expressed as log Cd in liver= 0.8799+0.913×log Dose (F=1116.1, r=0.9877) and log Cd in kidney= 0.2542+0.0653×log Dose (F=884.8, r=0.9845), respectively. Also, the correlation between hepatic and renal cadmium concentration was highly significant(p<0.01), and dose-response relationship was expressed as long Cd in kidney = -0.6649+1.0259×log Cd in liver (F=411.1, r=0.9676). I consider that this data will be useful for the further studying of low-dose cadmium toxicity.

Photodetector 용 GaAs MESFET의 최적설계에 관한 연구

洪淳錫,朴奉任 홍익대학교 산업기술연구소 2001 産業技術 Vol.11 No.-

In this paper, in order to analyze the optical response for the buried gate type GaAs MESFET photodetector, we derived the total sheet charge density at every channel position. In solving the carrier continuity equation under illumination, we divided the channel region into the depletion and neutral regions. In the depletion region, we considered the drift current only and used the suggested average value for the vertical electric field. While in the neutral region,we neglected the drift current component and suggested some boundary conditions.

노인정신장애 평가척도(Psychogeriatric Assessment Scale)의 한국판 표준화 연구

조맹제,박임순,신영민,김무진,정희연,정은기,최용성,조성진,서국희,함봉진 大韓神經精神醫學會 2000 신경정신의학 Vol.39 No.1

연구목적 : 본 연구는 치매와 우울증을 다차원적으로 평가할 수 있는 도구인 Psychogeriatric Assessment Scale(PAS)의 한국판(PAS-K)을 개발하기 위한 것이다. 방 법 : 번역, 역번역, 그리고 세차례의 예비조사를 통하여 PAS-K를 제작하였다. 60세 이상의 노인 291명(임상환자군 : 58명, 지역사회노인군 : 168명, 수용시설 거주자 : 67명)과 그들의 정보제공자들을 대상으로 PAS-K, Geriatric Depression Scale(GDS), Korean version of Mini-Mental State Examination(MMSE-K), Hamilton Rating Scale for Depression(HRSD), 그리고 Hachinski Ischemic Score 를 적용하고, Diagnostic Interview chedule(DIS-Ⅲ-R)을 사용하여 치매와 우울증을 진단하였다. PAS-K의 신뢰도와 타당도를 평가하고, 예민도와 특이도, Kappa값, 그리고 ROC커브 분석법을 이용하여 PAS-K의 6개의 소척도들(피검자면접 : 인지기능 장애척도, 우울척도, 뇌졸중척도, 정보제공자면접 : 인지기능 저하척도, 행동변화척도, 뇌졸중척도)의 최적 절단점을 구하였다. 결 과 : PAS-K는 높은 내적 일관성을 보였고, 검사자간 신뢰도도 만족할 만한 수준이었다. PAS-K의 소척도들을 다른 표준화된 검사도구들과 비교하였을 때 인지기능 장애척도와 인지기능 저하척도는 MMSE-K와, 우울척도는 GDS 및 HRSD와 유의한 상관관계를 보였으며, 뇌졸중척도는 Hachinski Ischemic Score와 통계적으로 의미있는 상관관계를 보였다. 최적절단점은 인지기능 장애척도 10점, 인지기능 저하척도 3점, 우울척도 5점, 피검자면접과 정보제공자 뇌졸중척도 모두 1점, 그리고 행동변화척도 2점으로 추정하였다. 결 론 : 본 연구를 통해 PAS-K의 신뢰도와 타당도가 검증되었고, 노인정신의학 역학연구나 보건분야에서 치매와 우울증의 임상경과관찰 및 일차 선별도구로서 유용하게 사용될 수 있게 되었다. Objectives : This study was designed to develop the Korean version of the Psychogeriatric Assessment Scale(PAS-K), a multidimensional screening tool for the dementia and depression. Methods : Through three times preliminary trials, the authors translated PAS into Korean. The PAS-K, Geriatric Depression Scale, Hamilton Depression Rating Scale, Hachinski Ischemic Scale and Mini-Mental State Examination-Korean version were administered to 291 subjects over the age of 60 and the same number of their informants(67 subjects were institutionalized, 168 subjects were in community, 58 subjects were psychiatric hospital patients). And the Diagnostic Interview Schedule(DSM-Ⅲ-R) was independently administered to exactly diagnose dementia and depression. The reliability and validity test, optimal cut-off point estimation for six each scale and ROC curve analyses were done to investigate the diagnostic validity of PAS-K. Results : Internal consistency and interrater reliability of the PAS-K were high. Concurrent validity of each scales of PAS-K was good in being measured with other standardized scales. The optimal cut-off points of each scale of the PAS-K were estimated as follows : 1) Stroke Scale of subject interview : 1, 2) Cognitive Impairment Scale of subject interview: 10, 3) Depression Scale of subject interview : 5, 4) Stroke Scale of informant interview : 1, 5) Cognitive Decline Scale of informant interview : 3, and 6) Behavioral Change Scale of informant : 2. conclusions : The PAS-K was valid and reliable screening tools for detecting dementia and depression. Therefore the PAS-K could be widely and extensively used in psychogeriatric epidemiological research or clinical setting of primary screening for dementia and depression.

환경행정공무원의 전문성과 환경행정의 규제성에 관한 조사연구 : 2001, 2003년 조사사례를 중심으로

정용택,박종안,손부순,이종화,장봉기,박정임 순천향대학교 기초과학연구소 2008 순천향자연과학연구 논문집 Vol.14 No.1

We have analyzed this influence base on survey of central government administration officers and local officers which were taken on 2001 and 2003. Also, we anticipates that this result would help actual field adjustment as well as preparation of speciality of officers. The results are summarized as follows : First, a survey in 2001 shows 68.8 percent of local administration officers answered that their expertise about environmental services were above average. Then, the result was increased to 82 percent of officers responsed that they have more than average expertise and experience in 2003 survey. Secondly, government have to increase effectiveness on regulation or restriction duty. Nonetheless, the survey shows that significant decrease of effectiveness from 2001 to 2003 in both central and local goveniment officers. It means that they spent more effort on local community environmental regulation program other than restriction duty to requisited from central government. Third, moreover, local government do not want to faculty of environmental administration and insists that governments need to set the regulation for particularity of regions.

Effects of Supplementation of FBS and PFF on In Vitro Maturation and Gene Expression Profiling of the Oocytes

Mi-Rung Park,Gi-Sun Im,Yeoung-Gyu Ko,Hwi-Cheul Lee,Eung-Woo Park,Seongsoo Hwang,Byoung-Chul Yang,Min-Kyu Kim,Jae-Gye Yoo,Soo-Bong Park,Jae-Seok Woo 한국동물번식학회 2009 Reproductive & Developmental Biology(Supplement) Vol.33 No.2s

돌발성 난청의 임상적 분석

박영균,임태승,이도용,김용기,최봉남 朝鮮大學校 附設 醫學硏究所 1997 The Medical Journal of Chosun University Vol.22 No.1

Sudden hearing loss(SHL) is defined as an abrupt onset of sensorineural hearing loss which develops over a period of hours or a few days without definitive cause. However, the etiology, treatment and prognosis of the sudden hearing loss are controversial at present time. Authors observed 33 cases(30 patients) with SHL who had been admitted and treated in our ENT department from January. 1992 to December, 1996.. They were evaluated by clinical and statistical analysis. The results were as follows : 1. Of the 33 cases, 8 cases(24.3%) had complete recovery, 6 cases(18.2%) had partial recovery, 3 cases(9.0%) had slight recovery and 16 cases(48.5%) had no response. 2. Those patients who were treated within 2 weeks from onset had better improvement(p<0.01). 3. Those patients who had ascending or flat audiogram pattern had better improvcment(p<0.05). 4. The patients with tinnitus had better improvement than those with vertigo(p<0.001).

A Temperature-Dependent Index of Mitotic Interval (τ0) in Haliotis gigantea and Haliotis discus

Park,In-Seok,Im, Jae Hyun,Lee, Young-Don,Kim, Bong-Lae,Han, Seock-Jung 한국유전학회 2003 Genes & Genomics Vol.25 No.1

In order to establish effective procedures for chromosome manipulation in Haliotis gigantea and H. discus, which are of enormous aquacultural potential, temperature-dependent measures of mitotic intervals (τ_0) were determined. Mitotic intervals (τ_0) in these abalone were determined by averaging the duration of the first and third embryonic divisions over a range of temperatures from 8 to 26℃. The relationships of each mitotic interval at two cell (τ_Ⅰ), four cell (τ_Ⅱ), eight cell (τ_Ⅲ), sixteen cell (τ_Ⅳ) and τ_0, to temperature (T in ℃) in H. gigantea were log τ_Ⅰ=176.1-28.3T, log τ_Ⅱ =199.5-12.4T, log τ_Ⅲ =236.2-12.2T, log τ_Ⅳ =269.3-14.1T and log τ_0 =83.1-32.8, respectively. The relationships of each mitotic interval at τ_Ⅰ, τ_Ⅱ, τ_Ⅲ, τ_Ⅳ and τ_0, to temperature in H. discus were log τ_Ⅰ=104.9-13.8T, log τ_Ⅱ =138.3-10.5T, log τ_Ⅲ =172.4-10.2T, log τ_Ⅳ =211.3-12.2T and log τ_0 =85.6-33.3T, respectively. There were strong, negative correlations between mitotic interval and water temperatures for all ten temperatures in these two species (H. gigantea: Y = -138.75 logX + 341.25, R^2 = 0.97; H. discus: Y = -112.33 logX + 255.22, R^2 = 0.98, where Y is mitotic interval and X is temperature).

天摩山 中腹의 억새型 群落의 構造와 그의 季節的 變化에 關하여

朴奉奎,任英子 梨花女子大學校 韓國生活科學硏究院 1974 韓國生活科學硏究院 論叢 Vol.12 No.-

This study was conducted from April, 1972 to Sep., 1972, in native grassland at Mt. Chun-Ma, Kyonggi-Do, where secondary succession took place. This survey adopted systematic sampling method and sampled 20 of 20x20 sq. cm. In each investigation, coverage, density, height, frequency of species were analyzed. The community structures were analyzed by the summed index {SDR_3(CDF, CFH0\), SDR_4, Ⅳ, PI} and the coefficient of homogeneity (CH_D, CH_C) of main herbs in each investigated sites on the 13th, Oct, 1972. This community can be said to be that of the Miscanthus sinensis-Arundinella hirta-Carex lancealata association. The dominant type by the combination of biological types are as follows: H-D_1-R_3-tu...... Sunned dominance ratio H-D_1-R_5-tu...... Species % The seasonal fluctuation of the main herbs in this community can be recognized with the summed dominance ratio, coefficient of homogeneity, and A/F ratio.

Detection of Heavy Metal Contents in Sesame Oil Samples Grown in Korea Using Microwave-Assisted Acid Digestion

Park, Min-Kyoung,Yoo, Ji-Hyock,Lee, Je-Bong,Im, Geon-Jae,Kim, Doo-Ho,Kim, Won-Il The Korean Society of Food Hygiene and Safety 2013 한국식품위생안전성학회지 Vol.28 No.1

본 연구에서는 유화제를 사용하지 않고 초단파 산분해법을 이용해 우리나라에서생산된 참기름의 중금속을 측정하고자 하였다. ICP-MS를 통해 12개의 참기름 시료에 오염된 카드뮴, 납, 비소의 3종 중금속을 분석하였다. 분석법의 검증 결과 카드뮴, 납, 비소 모두 직선성($r^2$)이 0.99 이상이며 RSD는 4% 이하였다. 또한, 분석법의 정확성 및 효율성 측정을 위해 중금속 $10{\mu}g/g$과 $100{\mu}g/g$을 첨가한 시료를 분석한 결과, 회수율이 카드뮴 98.5-101.6%, 납 100.3-101.3%, 비소 102.1-111.2%로 우수하게 나타났다. 본 분석법을 이용하여 분석한 참기름 시료의 중금속 함량은 카드뮴 불검출${\sim}0.109{\mu}g/g$, 납 $0.014{\sim}0.200{\mu}g/g$, 비소 $0.014{\sim}0.125{\mu}g/g$이었다. 따라서, 중금속 오염지역에서 생산된 참깨 및 이를 이용한 가공품의 경우 섭취에 주의할 필요가 있다. This study aimed to determine heavy metal contents in sesame oil samples produced in Korea through microwave-assisted acid digestion without using an emulsifier. Three heavy metal, cadmium (Cd), lead (Pb) and arsenic (As) in twelve sesame oil samples were determined by ICP-MS. The validation of analysis method was checked by standard addition method (10 and $100{\mu}g/kg$). As a result, linearity ($R^2$) was above 0.999 and RSDs were lower than 4%. The recovery of Cd, Pb and As ranged between 98.5-101.6%, 100.3-101.3%, and 102.1-111.2%, respectively. The detected ranges in sesame oil samples were as follows; N.D. to $0.109{\mu}g/g$ for Cd, 0.014 to $0.200{\mu}g/g$ for Pb and 0.014 to $0.125{\mu}g/g$ for As, respectively. Therefore, sesame seeds and products grown in heavy metal-polluted regions which are used as food should be given priority attention and consideration.