이식 환자 간호에 대한 윤리적 갈등

손희진,최미혜 중앙대학교 의과대학 간호학과 간호과학연구소 2000 중앙간호논문집 Vol.4 No.2

This is description investigational research on ethical conflicts of nurses who have the experience of nursing organ transplant patients. With the help specialists a researcher collected information through survey sheets on 171 nurses who have the experience of nursing organ transplant patients in one university hospital from 11th August 2000 to 17th August 2000. The Credibility rates of used tools are like these. Chronbach's α= 0.794 for survey sheets on ethical conflicts and Chronbch's α= 0.894 for survey sheets on decision makings. The collected information was analysed with SPSS. Investigational variables of ethical conflicts and decision makings were arranged using real numbers, percentage, averages, standard deviations, and t-test and ANOVA was used on variables influencing ethical conflicts. 1. Conclusion 1) The nurses surveyed in this research are nursing 4.4 organ transplant patients on an average per month with their families. Livers were transplant with top frequencies. Most of the nurses themselves and their families had no experience of diseases. 2) Vocational morals of the 85% nurses surveyed are shaken sometimes and changes with circumstances. 3) Ethical conflicts rates concerning nursing organ transplant patients ranged from 40 minimum to 130 maximum with an average of 94.70. The conflict rate of relationships with organ transplant patients and their families was especially high and that of brain death nursing showed a low conflict rate. 4) Nurses who had experineces of deciding against their own ethical sense of value to solve ethical conflicts problem rated 31.0%, 24.6% of them changed their moral standards. Firstly, the demands of doctors, secondly, the demands of their own protections, thirdly, the demands of supporters of families. 50% of the nurses followed the decisions with don't care attitudes when there are ethical conflicts and 40% of them developed their own opinion and sought alternatives. 5) General characters of the nurses had differences according to their religious background and disease experience. 2. Suggestion Suggest that methodological researches are needed to develope ethical conflict investigation tools for organ transplant patients nursing.

의료 질 향상 사업의 성공요인과 실패요인

최귀선,이선희,조우현,강혜영,채유미 한국의료QA학회 2001 한국의료질향상학회지 Vol.8 No.2

Background : To propose effective strategies for successful implementation of QI in health care institutions, by identifying facilitating factors and barriers to conducting QI programs. Methods : In order to examine empirical evidence on the success factors or barriers to QI implementation in hospitals, a literature study was performed on the basis of MEDLINE search. Among the identified literature. 13 provided reliable findings and basis comprehensive discussion on this issue and thus were selected for in-depth analysis. A mailed questionnaire survey was conducted for hospital CEOs and QI directors of hospitals with 400 beds or greater to investigate what attributes of their organizations they perceived as success factors or obstacles to QI implementation. Result : The analysis of selected literature and survey results presented that the primary factors considered to be most important as successful implementation of QI were: strong support from hospital CEOs, setting higher priority for QI activities, continuous and persistent efforts in QI activities, and active participation of clinical staffs. The barriers identified in this study were : the lack of orientation and understanding of QI concepts, low level of interest and participation of physician in QI programs, the lack of evaluation and rewarding system for QI activities. Conclusion : By identifying factors that affect facilitation of QI, the study results will be of great use for either institutions being in the early stage of evolving QI or those looking for better strategies to achieve more active and persistent QI implementation in their institutions.

시각적 피드백을 병행한 어깨복합운동프로그램이 어깨비대칭 청년들의 어깨 근력과 정렬에 미치는 영향

강순희, 강은지, 목미경, 박지연, 손혜림, 연우정 한국교통대학교 2016 한국교통대학교 논문집 Vol.51 No.-

The purpose of this study was to identify whether shoulder complex exercise program with visual feedback could improve the shoulder muscular strength and postural alignment in adolescents with shoulder asymmetry. Twenty eight subjects were recruited from the K university and divided into three groups: experimental 1, 2group(Each n=10) and control group(n=8). For 4 weeks, the experimental group 1 performed shoulder muscle complex exercise program and the experimental group 2 performed shoulder complex exercise program with visual feedback. The control group did not perform exercises. The shoulder muscle strength and difference between the height of left and right shoulders were assessed before, after training using the hand-held dynamometer and Global Posture System. Subordination variables, general characteristics analysis, χ² test and Kruskal Wallis H test were conducted to evaluate differences between groups and training before, after changes were checked Wilcoxon signed rank test with using the PASW 18.0 statistical program. The results of the study were as follows. 1) Both the experimental 1, 2group showed improvements in muscle strength of several muscles following training (p<.01). The control group showed significant reduction in the left posterior deltoid (p<.05), and did not show significant changes in examining other muscles (p>.05). And there were differences among three groups in shoulder muscle strength (p<.001). Muscle strength changes in several muscles were greater in the experimental 1, 2group compared with the control group (p<.001). Muscle strength changes in the several muscles were greater in the experimental group 2 compared with the experimental group 1 (p<.001) 2) Both the experimental 1, 2group showed significant decreases in the difference between the left and right shoulder heights following training (p<.01). The control group did not show change (p>.05). Changes in the difference between the left and right shoulder heights were greater in the experimental 1, 2group compared with the control group (p<.001).

정상교하 아동의 두개안면부 성장에 관한 종적 연구

양규호,박창헌,손정수,김낙현,최남기,김선미,김기백,신혜성 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.3

혼합치열기 정상교합 아동 24명(남:14명 여:10명 초진 시 평균 나이 9±1.3세, 평균 관찰 기간: 13±1.3개월)에 대한 성장량을 측정하여 기능적 교정장치의 순수 치료효과를 평가하는데 도움이 되기 위해 3회(5~8개월 간격) 촬영한 측모 두부 방사선 규격 사진에 대한 분석 결과 다음과 같은 결론을 얻었다. 1. 남아는 상악골은 전하방, 하악골은 전방성장하였고, 여아는 상하악골이 전하방 성장하였다(p<0.05). 2. 상하악골의 남녀간 차이에서 수평적 성장상태는 여아가 컸고(A point 여아: 2.39mm, 남아: 1.26mm, p<0.05), 수직적 성장상태는 유의한 차이가 없었다. 3. 상악 전치의 치축은 두개저에 대해서 순측 경사하였고(p<0.01) 하악 전치의 치축은 큰 변화가 없었다. The purpose of this study was to provide the reference data evaluating the treatment effect of orthopedic appliances. The skeletal and dental growth increments were measured in 24 normal mixed dentition children(boys: 14, girls: 10) by three serial lateral cephalograms: initial mean age: 9±1.3 years, mean observation period: 13±1.3 months, Cephalometric changes were analysed. The results were as follows: 1. In boys, the maxilla showed forward and downward growth pattern and the mandible showed forward growth pattern(p<0.05). In girls, the maxilla and mandible showed forward and downward growth pattern(p<0.05). 2. Horizontal growth of both maxilla and mandible in girls was superior to those in boys(A point: girls: 2.39mm, boys: 1.26mm, with p<0.05), whereas vertical growth of both maxilla and mandible in boys was similar to those in girls. 3. The change in tooth axis showed labioversion of upper incisor(p<0.01) and comparatively stable lower incisor position.

대동맥 협착증과 동반된 출혈성 위장관 동정맥 기형에서 Estrogen-Progesterone 치료 1예

김도연,김화정,김효정,남준식,박수영,박영미,신정은,주미순,황민규,정혜경,손혜영,이선영,이한주 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

Bone Generation Following Repeated Administration of Recombinant Bone Morphogenetic Protein 2

Son Hye-Ju,Lee Mi Nam,Kim Yuri,Choi Hyuck,Jeong Byung-Chul,Oh Sin-Hye,김정우,Kwon Seung-Hee,Kim Sun-Hun,Song Soo-Chang,Lee Shee Eun,Koh Jeong-Tae 한국조직공학과 재생의학회 2021 조직공학과 재생의학 Vol.18 No.1

Background: The delivery of recombinant human bone morphogenetic protein 2 (rhBMP2) by using various carriers has been used to successfully induce bone formation in many animal models. However, the effect of multiple administration of rhBMP2 on bone formation and BMP2 antibody production has not been determined. Our aim was to examine the bone formation activity of rhBMP2 and serum levels of anti-BMP2 antibodies following the repeated administration of rhBMP2 in mice. Methods: Absorbable collagen sponges or polyphosphazene hydrogels containing rhBMP2 were subcutaneously implanted or injected into one side on the back of six-week-old C57BL/6 mice. Three or 4 weeks later, the same amount of rhBMP2 was administered again with the same carrier into the subcutaneous regions on the other side of the back or into calvarial defects. The effects of a single administration of rhBMP2 on the osteoinductive ability in the ectopic model were compared with those of repeated administrations. In vivo ectopic or orthotopic bone formation was evaluated using microradiography and histological analyses. Serum concentrations of anti-rhBMP2 antibodies were measured by ELISAs. Results: Re-administration of the same amount of rhBMP2 into the subcutaneous area showed a comparable production of ectopic bone as after the first administration. The bone forming ability of repeated rhBMP2 administrations was equal to that of single rhBMP2 administration. The administration of rhBMP2 into calvarial defects, following the first subcutaneous administration of rhBMP2 on the back, completely recovered the defect area with newly regenerated bone within 3 weeks. Repeated administration of rhBMP2 at 4-week intervals did not significantly alter the serum levels of anti-BMP2 antibodies and did not induce any inflammatory response. The serum obtained from rhBMP2-exposed mice had no effect on the ability of rhBMP2 to induce osteogenic gene expressions in MC3T3-E1. Conclusion: We suggest that the osteoinductive ability of rhBMP2 is not compromised by repeated administrations. Thus, rhBMP2 can be repeatedly used for bone regeneration at various sites within a short duration. Background: The delivery of recombinant human bone morphogenetic protein 2 (rhBMP2) by using various carriers has been used to successfully induce bone formation in many animal models. However, the effect of multiple administration of rhBMP2 on bone formation and BMP2 antibody production has not been determined. Our aim was to examine the bone formation activity of rhBMP2 and serum levels of anti-BMP2 antibodies following the repeated administration of rhBMP2 in mice. Methods: Absorbable collagen sponges or polyphosphazene hydrogels containing rhBMP2 were subcutaneously implanted or injected into one side on the back of six-week-old C57BL/6 mice. Three or 4 weeks later, the same amount of rhBMP2 was administered again with the same carrier into the subcutaneous regions on the other side of the back or into calvarial defects. The effects of a single administration of rhBMP2 on the osteoinductive ability in the ectopic model were compared with those of repeated administrations. In vivo ectopic or orthotopic bone formation was evaluated using microradiography and histological analyses. Serum concentrations of anti-rhBMP2 antibodies were measured by ELISAs. Results: Re-administration of the same amount of rhBMP2 into the subcutaneous area showed a comparable production of ectopic bone as after the first administration. The bone forming ability of repeated rhBMP2 administrations was equal to that of single rhBMP2 administration. The administration of rhBMP2 into calvarial defects, following the first subcutaneous administration of rhBMP2 on the back, completely recovered the defect area with newly regenerated bone within 3 weeks. Repeated administration of rhBMP2 at 4-week intervals did not significantly alter the serum levels of anti-BMP2 antibodies and did not induce any inflammatory response. The serum obtained from rhBMP2-exposed mice had no effect on the ability of rhBMP2 to induce osteogenic gene expressions in MC3T3-E1. Conclusion: We suggest that the osteoinductive ability of rhBMP2 is not compromised by repeated administrations. Thus, rhBMP2 can be repeatedly used for bone regeneration at various sites within a short duration.

Production of Flavonoid O-Glucoside Using Sucrose Synthase and Flavonoid O-Glucosyltransferase Fusion Protein

Mi Hye Son,Bong Gyu Kim,Dae Hwan Kim,Mi Rim Jin,Kwang Pyo Kim,Joong Hoon Ahn 한국미생물 · 생명공학회 2009 Journal of microbiology and biotechnology Vol.19 No.7

Comparison of Cell Mediated Immune Response in Pigs Vaccinated Intradermally and Intramuscularly with Oil-adjuvanted FMD Vaccine

Mi Hye Son,Kwang Nyeong Lee,Jang Kwan Hong,Ji Hyeon Hwang,Su Mi Kim,Byoung Han Kim,Jong Hyeon Park 대한수의학회 2014 대한수의학회 학술대회발표집 Vol.2014 No.-

Poster Session : Anti-inflammation activity of compounds isolated from Scutellaria baicalensis Georgi

( Mi Hye Kim ),( Hye Kyung Ha ),( Ho Young Lee ),( Da Young Jung ),( Su Jin Lee ),( Ji Yoon Choi ),( Hwan Soo Choi ),( Chung Sook Kim ),( Kun Ho Son ) 생화학분자생물학회 2006 생화학분자생물학회 춘계학술발표논문집 Vol.2006 No.-

호텔근무환경의 심리적 압박감이 이직의사에 영향을 미치는 구조적 연구

손미혜(Mi Hye Son),남승민(Seung Min Nam),신승철(Seung Chul Shin),신홍철(Hong Chul Shin) 한국관광연구학회 2014 관광연구저널 Vol.28 No.6

This study has intention to propose some directions and guidelines for managing hotel employee`s effectively through researching about affections of job satisfaction from job stress, affections of job involvement and the relationship between job involvement and turnover intention for human resource management which is a core factor of hotel industry. From result of this study, Job stress gives negative impact to job involvement indirectly. it may show that on-going care those who have high job stress influence turnover intentions indirectly. Actually the guideline of human resource management in hotel industry is not obvious and studies on this agenda are not sufficient. If a direction of hotel human resource management may point toward not revenue and task-oriented but employee’s job stress and satisfaction, it will execute human resource management more efficiently and effectively. Further more it must influence to job performance and productivity and increase competitiveness of hotel industry from customer satisfaction.