보리등겨로 제조한 간장의 향기성분

권오준,이은정,최웅규,손동화,이석일,정연건,지원대 한국위생과학회 2002 한국위생과학회지 Vol.8 No.2

새로운 장류제품으로서 보리등겨의 이용방안을 모색하기 위하여 간장을 만들어 연구하였다. 보리로 제조한 간장의 갈색화는 점차적으로 증가 하였으며 완만한 변화를 보였다. 향기성분으로는 4-vinyl-2-methoxy-phenol, benzeneacetaldehyde, palmitic acid, 2-furancatboxaldehyde, methyl-9, 12-octadecadienoate, di-(2-ethylhexyl)phthalate, diethyl phtalate, dibytyl-1,2-benzenedicatboxylate, 5-methyl-2-furancarboxaldehyde, 3,4-dimethyl-1h-pyrazole, phenylethyl alcohol, dioctyl-hexanedioate, dimethyl-1,2-benzenedicatboxylate, benzaldehyde, methional, 2-methoxy-phenol, n-furfurylidene-3-methylbutyl amine, 1-furfuryl-2-formyl pyrrole, tetradrcanoic acid, 5-methyl-pyrimidine, 4-methyl-5-hydroxymethyl-imidazole, maltol, 5-(5-methyl-2-furanyl)methyl-2-furancarboxaldehyde 순으로 높은 함량을 차지 하였다. For investigation of new utilization as jang-products, kanjang was prepared using barely bran. This study was conducted to investigate flavor components of kanjang during fermentation time. The optical density was gradually increased. Among the flavor components identified in kanjang made with barley bran, the contents of 4-viny1-2-methoxy-phenol was the most in quantity followed by benzeneacetaldehyde, palmitic acid, 2-furancarboxaldehyde, methyl-9,12-octadecadienoate, di-(2-ethylhexyl)phthalate, diethyl phtalate, dibutyl-1,2-benzendicarboxylate, 5-methyl-2-furancarboxaldehyde, 3,4-dimethyl-1h-pyrazole, phenylethyl alcohol, dioctyl-hexanedioate, dimethyl-1,2-benzenedicarboxylate, benzaldehyde, methional, 2-methoxy-phenol, n-furfurylidene-3-methylbutyl amine, 1-furfuryl-2-formyl pyrrole, tetradecanoic acid, 5-methyl-pyrimidine, 4-methyl-5-hydroxymethyl-imidazole, maltol and 5-(5-methyl-2-furanyl)methyl-2-furancarboxaldegyde.

Nutrients Release from Seo-Naktong River Sediments and Effect of Some Environmental Parameters in the Continuous Flow System

Yoon, I.-K 韓國陸水學會 1999 생태와 환경 Vol.32 No.1

전경대원에서 발생한 결핵의 임상 양상

문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

Effect of Feeding Far Infrared Irradiated Rice on Rate of Laying Eggs and Vitamin of Egg

Kwon. O-Jun,Choi. Ung-Kyu,Kim. Dae-Gon,Kim. Sung-Hong,Son. Dong-Hwa 한국축산식품학회 2004 심포지움 및 학술발표회 Vol.- No.33

This study was conducted to investigate change of rate of laying eggs and vitamin according to feeding of far infrared-irradiated rice. The feeding of rice irradiated by far infrared rays did not affect the body weight of laying hens, but the rate of laying eggs were 14% positively increased than normal rice. Especially, the levels of vitamin A(150~200%), D(28~30%) and E(40~67%) were much higher in the group of laying hens fed with rice irradiated by far infrared rays.

Antioxidant and Anti-Inflammatory Effects of Rhei Rhizoma and Coptidis Rhizoma Mixture on Reflux Esophagitis in Rats

Kwon, O Jun,Kim, Min Yeong,Shin, Sung Ho,Lee, Ah Reum,Lee, Joo Young,Seo, Bu-il,Shin, Mi-Rae,Choi, Hyun Gyu,Kim, Jeong Ah,Min, Byung Sun,Kim, Gyo-Nam,Noh, Jeong Sook,Rhee, Man Hee,Roh, Seong-Soo Hindawi Publishing Corporation 2016 Evidence-based Complementary and Alternative Medic Vol.2016 No.-

<P>The purpose of this study was to investigate the antioxidant and anti-inflammatory effects of the combined extract of Rhei rhizoma and Coptidis rhizoma (RC-mix) in experimental model of acute reflux esophagitis. The antioxidant activity was assessed by<I> in vitro</I> 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays. RC-mix was given at 100, 200, and 400 mg/kg body weight 2 h prior to induction of reflux esophagitis (RE). After 5 h, the effects of RC-mix treated rats were compared with those of normal and control rats. The representative flavonoid contents of RC-mix, such as sennoside A, epiberberine, coptisine, palmatine, and berberine, were detected using HPLC. The elevated esophageal mucosa damage was markedly ameliorated by RC-mix treatment in a dose-dependent manner. Furthermore, the administration of RC-mix reduced the increase of serum reactive oxygen species (ROS) and peroxynitrite (ONOO<SUP>−</SUP>). The improvement of superoxide dismutase (SOD) and heme oxygenase-1 (HO-1) levels were marked in the group given RC-mix. Moreover, the elevation of inflammatory mediators and cytokines by nuclear factor-kappa B (NF-<I>κ</I>B) activation in control rats decreased by RC-mix pretreatment. These results indicate that RC-mix treatment reduces the pathological states of esophagitis<I> via</I> regulating NF-<I>κ</I>B mediated inflammation related to oxidative stress. </P>

상엽(桑葉) 추출물의 Adipogenesis 억제를 통한 항비만 활성 평가

권오준 ( O Jun Kwon ) 대한본초학회 2016 大韓本草學會誌 Vol.31 No.5

Objectives:Mori Follium (Morus alba L. leaf) has been cultivated in many Asian countries. Especially, mulberry leaf has been used as an anti-diabetic remedy in oriental medicine. However, anti-obesity effect of mulberry has not been unknown. In this study, our objectives of study is to investigate the anti-adipogenic effect of mulberry water extract (MLE) and to reveal potential molecular anti-obesity mechanism in 3T3-L1 adipocytes differentiation model. Methods : The cytotoxicity of MLE in 3T3-L1 was examined by MTT assay. Anti-adipogenic effect of MLE was evaluated by Oil Red O (ORO) staining. To elucidate the molecular mechanism, inhibitor assay was employed. The mRNA expression levels of adipogenic transcriptional factors such as PPARγ and fatty acid synthase (FAS) were analyzed by reverse transcription-polymer chain reaction (RT-PCR) analysis. Results:The MLE treatment for 24 h did not affect to the 3T3-L1 cells at concentrations of 1, 10, 100, 200, 400, 800 and 1,000 ㎍/㎖. Thus, non-toxic concentration rages of MLE were used during adipogenesis period (day -2 to 7). Intracellular lipid accumulation in MLE-treated 3T3-L1 adipocytes (day 6) were quantitatively evaluated by ORO staining. The MLE treatment significantly and dose-dependently suppressed 3T3-L1 adipogenesis by 60.42%, 38.24%, and 5.97% at 10, 100, and 200 ㎍/㎖, respectively. In addition, our inhibitor assay and RT-PCR analysis revealed that the MLE-inhibited 3T3-L1 adipogenesis through inhibition of PPARγ mediated by Wnt/β-catenin signaling pathway. Conclusions: In conclusion, these findings indicate that the MLE could be used in prevent and/or treatment of obesity-related diseases.

상엽(桑葉) 추출물의 미백활성 및 피부섬유구조 형성에 미치는 효과

권오준 ( O Jun Kwon ) 대한본초학회 2016 大韓本草學會誌 Vol.31 No.5

Objectives:The Skin is composed of multiple layers, including the epidermis, dermis, and hypodermis. It provides a vital barrier structure that protects vertebrates from external environmental antigens, solvents, ultraviolet light, microorganisms, toxins, and weather conditions. Although several biological effects of Mori Follium have been reported, beneficial effects of Mori Follium in skin health remain unclear. In this study, we prepared water extract of Mori Follium (MLE) and evaluated the effects on melanin accumulation and expression levels of skin fibril-related proteins. Methods : The cytotoxicities of MLE in B16F10 melanoma and human skin fibroblasts (HSF) were examined by MTT assay. Inhibitory effect of MLE on the α-MSH- and IBMX-induced melanosis in B16F10 melanoma was examined. The expression levels of fibronectin, collagen 1α2, and CCN2 in MLE-treated HSF were analyzed by reverse transcription-polymer chain reaction (RT-PCR) and western blotting. Results:The MLE treatment for 24 h did not affect to the B16F10 and HSF at concentrations of 1, 10, 50, 100, 200, 400 and 800 ㎍/ml. The MLE treatment for 72 h significantly and dose dependently suppressed melanin accumulation in B16F10 melanoma. In addition, the MLE treatment up-regulated expression levels of skin fibril-related genes such as fibronectin, collagen 1α2, and CCN2 in HSF. Our western blot analysis revealed MLE-induced up-regulation of skin fibril-related genes required the activation of CCN2 protein. Conclusions: In conclusion, these findings suggest that the MLE could be used in development of cosmetic natural material of maintaining healthy skin.

관리기 부착식 운반 겸용 리프터 설계

권오준 ( O Jun Kwon ),김호찬 ( Ho Chan Kim ),김태우 ( Tae Woo Kim ),김태형 ( Tae Hyeong Kim ),정준혁 ( Jun Hyeok Jeong ),황순용 ( Soon Yong Hawang ),이진경 ( Jin Gyeong Lee ),반길환 ( Gil Hwan Ban ),하유신 ( Yu Shin Ha ) 한국농업기계학회 2016 한국농업기계학회 학술발표논문집 Vol.21 No.2

현재 밭농업 기계화율은 50%로 정부의 기계화율 정책 목표인 70%에 미치지 못하고 있다. 농업현장은 고령화가 가속되고 있고 고령화된 농민들에게는 밭에서 수확된 농산물을 운반 적재하기가 매우 힘이 드는 문제점이 있다. 산업현장에서는 리프트기와 같은 주행과 운반 적재작업을 할 수 있는 최적화 된 기계는 많이 존재하지만 고가이며 농경지에서 주행이 불가능한 형태이다. 따라서 오프로드에서 주행성을 확보해 작업능률 향상과 비용절감 효과를 가져 오며 고령화와 여성화가되고 있는 농민들이 쉽게 사용할 수 있도록 관리기 부착식 운반겸용 팔레트 적재가 가능한 리프트기를 개발하였다. 본 설계는 탈부착이 가능한 연결장치와 유압유니트를 이용해 상하로 이동하는 유압실린더, 관리기의 동력을 이용해서 팔레트 운반이 가능하도록 리프트기를 운행할 수 있도록 설계 및 제작하였다. 관리기(국제종합기계, KRC 80R)는 최대출력 6.5 hp, 정격출력 5.0 hp, 리프터는 대경리프터 1.0T로 선정하였다. 적재하중은 100 kg으로 설정하고 이에 따라 유압실린더 및 유압펌프는 실린더 내경 40 mm, 피스톤 로드경 28 mm, 실린더 단면적 12.56 cm², 실린더 압력7.95 kg/cm², 실린더 속도 5 cm/s, 유량 4 L/min으로 설계하였다. 또한 리프터에 장작할 바퀴는 바퀴당 허용하중이 최소 175 kg 이상인 농업용 바퀴를 선정하였다. 관리기의 최대출력은 6.5 hp이지만 정격출력 5 hp를 고려하면 337.5 kg을 4 km/h 속도로 주행할 수 있다. 리프터 자체 중량150 kg 이하, 관리기 본체 중량 70 kg로 자중은 200 kg 이며, 137.5 kg 정도 사용하중에 여유가 있다. 따라서 적재하중을 100 kg 설정하여 관리기 엔진의 부하를 줄였으며 또한 바퀴는 실제하중320 kg을 고려하여 바퀴 당 허용하중이 175 kg 이상인 고무통바퀴를 선정하여 오프로드에서 주행성을 확보하였다. 또한 오프로드 특성을 고려하여 관리기와 리프트기의 연결부위, 리프트기의 주행부에 차량용 서스펜션을 개선한 완충스프링을 설계하여 진동의 취약성을 보완하였다. 향후 설계제작된 시작품을 밭 농업 포장에서 주행 테스트와 작업성능 측정을 통하여 수정 보완할 예정이다.

보리등겨로 제조한 간장의 최적 발효 조건

권오준(O-Jun Kwon),손동화(Dong-Hwa Son),최웅규(Ung-Kyu Choi),이석일(Suk-Il Lee),임무혁(Moo-Hyeg Im),조영제(Young-Je Cho),양성호(Sung-Ho Yang),김성홍(Sung-Hong Kim),정영건(Yung-Gun Chung) 한국식품과학회 2001 한국식품과학회지 Vol.33 No.5

ECG 신호의 전력선 잡음 제거를 위한 디노이징 딥 오토인코더

권오윤(O-Yun Kwon),이지은(Jee-Eun Lee),임성준(Seong-Jun Lim),권준환(Jun-Hwan Kwon),이병채(Byung-Chae Lee),이건기(Gun-Ki Lee),유선국(Sun-Kook Yoo) 대한전기학회 2020 대한전기학회 학술대회 논문집 Vol.2020 No.7