당뇨병환자에서 뇨증 Fibronectin농도의 증가에 관한 연구

한승범,조준승,손건영,서성문,박근용,조성래,박규영,박정모,이인규,여준기 啓明大學校 醫科大學 1994 계명의대학술지 Vol.13 No.4

Plasma fibronectin is an α₂-glyoprotein, which is produced by vascular endothelial cells. Raised level of plasma fibronectin has been observed in diabetic patients particularly in the presence of microvascular complications. However, no available data exist about urine level of this glycoprotein in diabetic patients. We measured urine fibronectin level by ELISA methods in 54 diabetic patients who have microvascular comlications or not. The following results were obtained. 1) Urine fibronectin level(㎍/g creatinine) in diabetic group(1740.0±678.0) is increased compaired with those in normal control group(471.0±59.0). but this results were not significantly different among two groups(P>0.05). 2) Urine fibronectin level(㎍/g creatinine) was significantly increased in patients with nephropathy (6188.0±3144.0) compared with those in normal control group(471.0±59.0) and patients without nephropathy(645.0±251.0)(P<0.001). 3) There were a significant correlation between BUN, creatinine, creatinine clearance, 24hr urine total protein and urine fibronectin level in diabetic patients. Our data suggest that urine fibronectin excretion level might be used as a sensitive guide for diabectic nephropathy.

「스포츠 科學」의 명칭 및 체계화에 대한 고찰

유근직,한상준 江原大學校附設 體育科學硏究所 1992 江原大學校附設體育科學硏究所論文集 Vol.- No.17

This study's objects are to survey the reason and background of name change from Science of Physical Education to Sport Science, and the problems of system. This study also comprehends the situation and the research trend of these problems in Germany and Japan, and wants to find the question and the needs at Sport Science. the results are as follows: First, we came to know the trend of world physics changes and advances very fast and innovafively. Under the notion of Sport Science, School physics has changed from Physical Education to Sport Education. Not only the curriculum title but also the curriculum meaning, the treat of teaching aids and the scope of teaching aids have changed, and the contents of sport has been various. Second, Sport Science is authorized and settled, systemically after outgrowing the physics which is the son of Pedagogics. But in scientific structure, paradigm and theory, Sport Science has many works to do. From the results of above study, we can get some solutions. - We should discuss and take an interest in the research matter and academic character for the Sport Science to stand for itself. - We should recognize the need of integrated theory and the importance of interdisciplinary approach. - We should watch out the research trend and world communication. - We should endeavor to use strict special words including the name problem, and to get the originality of Sport Science.

인체 대장암에서 72kDa 제 4형콜라겐 분해효소의 발현

김정은,손건영,전수한 경북대학교 병원 1998 경북대학교병원의학연구소논문집 Vol.2 No.1

수술 절제한 대장암 45예에서 Northern blot analysis와 gelatin zymography를 시행하여 72kDa 제 4 형콜라겐 분해효소의 mRNA치와 활성도를 조사하였다. 대장암에서 주위 정상조직에 비해 이 효소의 mRNA치가 증가하였으며 단백질 합성단계에서 효소의 활성도와도 연관되었다. 특히 활성형인 62kDa의 활성도가 크게 증가하였다. 암진행에 따른 이 효소의 활성도 변화는 T2와 T3에서 암조직과 정상조직사이에서 mRNA치와 효소활성도에 차이가 있었으나 전반적으로 암의 침윤도, 림프절 전이, 듀크스 병기에 따른 유의한 차이는 볼 수 없었다. 암침윤과 전이에는 제 4 형콜라겐 분해효소 외에 딴 metalloproteinase들, plasminogen activator등 여러 가지 다른 단백질 분해효소도 관여하며, 암종류에 따라 이들 효소의 작용정도가 차이가 날 수 있다. 또 조직 억제제인 tissue inhiitors of metalloproteinase(TIMPs)와의 균형관계도 고려해야 한다. 그러므로 대장암에서 72kDa 제 4 형콜라겐 분해효소의 증가된 활성양상을 이들 다른 인자들과 함께 관찰하면 암의 진행정도를 나타낼 수 있는 보다 뚜렷한 지표를 만들 수 있을 것으로 생각된다. Type Ⅳ collkagenases are thought to play a role in the proteolysis of the basement membrance and the extracellular matrix by the malignant cells that occur early in the development of invasive tumors. In several human tumors, including breast, colonic, ovarian, and gepatocellular carcinomas, Type Ⅳ collagenase expression has been positively correlated with tumor invasiveness. In this study, we examined the expression and the activation of 72kDa Type Ⅳ collagenase in cancerous and normal tissues of the colon and, we attempted to clarify its clinical significance in 45 cases of human colorectal cancer by using northern blot analysis and gelatin zymography. This study showed that the level of 72kDa Type Ⅳ collagenase mRNA was increased in colorectal cancer and that this increase was associated with increased enzymatic activity. While there was a difference in the expression and the activation of this enzyme between T2 and T3, this enzyme activity did not show a definite correlation with cancer progress as measured by the depth of tumor invasion and lymph node metastasis.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

韓國河川의 流出率과 流出指標로서의 洪水直前 流量

金熙鍾,柳又秀,金佳鉉,申東守,韓健模,全裕燦 東亞大學校 大學院 1984 大學院論文集 Vol.9 No.-

This paper is a study on relation between run-off ratio and antecedent discharge, run-off ratio and antecedent discharge per unit area, antecedent discharge and antecedent precipitation, by the data from the five major river basins in Korea and the small river basins in Pusan. The Nak-Dong rivers(An-Dong upper stream) f=0.4780+0.0124 ln qA r=0.99 qA=0.3368e0.1101R r=0.99 f=0.5793+0.0146 ln(qA/A) r=0.99 The Nak-Dong rivers except Ga-song station f=0.2017-0.0840 ln qA r=0.75 f=0.7012+0.0750 ln(aA/A) r=0.71 The Han rivers f=-0.0035+01267 on qA r=0.75 f=1.1311+0.1263 ln(qA/A) r=0.71 L=302.9064-43.8490 ln qA r=0.84 The Geun rivers(Mu-sin Cheon) f=0.295+0.1823 ln qA r=0.93 f=0.8417+0.1823 ln(qA/A) r=0.93 L=40.0456+62.0346 ln qA r=0.94 The Yeong-san rivers f=0.3766+0.0598 ln qA r=0.79 f=0.8084+0.0599 ln(qA/A) r=0.79 The Seom-jin rivers f=-1.3875+0.6505 ln qA r=0.92 f=2.1633+0.3465 ln(qA/A) r=0.76 Small river basin in Pusan f=0.3635+0.1120 ln qA r=0.87

Entanced Summer Pasture Utilization Through Overseeded Warm-Season Annual Legumes

Kun-Jun Han 한국초지조사료학회 2016 한국초지조사료학회 학술대회논문집 Vol.2016 No.08

Effect of Overseeded Forage Radish for Improving Soil Properties and Recovering Excessive Nitrogen in Southern Pastureland

Kun-Jun Han,Manoch Kongchum,Wink Alison,Mike Mccormick 한국토양비료학회 2014 한국토양비료학회 학술발표회 초록집 Vol.2014 No.6

Considerations for tall fescue pastrue establishment & utilization

Kun-Jun Han 한국초지조사료학회 2013 한국초지조사료학회 학술대회논문집 Vol.2013 No.09

다초종 조파를 통한 다년생 초지 토양 및 식생 개선

Prof. Kun-Jun Han 한국초지조사료학회 2015 한국초지조사료학회 학술대회논문집 Vol.2015 No.11

旋削作業에서 振動이 被加工物表面粗度에 미치는 영향 : 工具角은 일정하고 切削條件을 變數로 함 Fixed: Tool angle, Variable: Cutting Condition

全漢軍 울산과학대학 1977 연구논문집 Vol.2 No.-

自動旋盤 및 高速旋盤 等의 出現이래 선반작업은 機械工業의 重要한 역할을 담당하여 왔다. 旋盤製品에서 表面良否의 原因은 선반작업중 被加工物의 表面粗度에 關係되는 要因을 分析하면 被加工物의 回轉速度의 大小, 切削速度(Cutting Speed)의 大小, 칩형성(Chip formation) 및 선반의 振動, 바이트(Bite)의 형상 等이 있으나 本硏究에서는 선반의 振動이 被加工物의 表面粗度에 미치는 영향을 究明한 結果 다음과 같은 結論을 얻었다. ① 선반작업에서 발생되는 진동수는 1∼100C/S 범위내에 있고 공구대와 주축의 진폭이 제일 크다. ② 剛性과 安定性이 있는 선반공구로써 旋削한 加工面에는 移送자국에 균등한 pitch가 週期的으로 나타난다. ③ 脆性材料인 단조용 黃銅材인 加工面의 粗度가 移送에 의한 영향이 거의 없고 수직방향의 진폭이 加工面을 불량하게 한다. ④ 被加工物의 粗度에 미치는 확정因子의 절삭속도, 공구의 재질, 바이트의 형상, 構成刃部, 溶着物 보다 정상가동 영역에서 發生된 振東이 粗度에 미치는 영향이 크다. Since the automatic and high speed lathes appeared, they have been played as one of the important roles in the mechanical industry. By analyzing the surface roughness of the materials manufactured with the lathe, I found out that there were several influences connected with the rotating speed of the material, cutting speed, chip formation, the lathe vibration, the bite shape and so on. Particullarly, I investigated the influcences of the lathe vibration on the given material and obtained the results as follows; ⑴ The vibration numbers in the lathe work belong within the boundary of 1-100cps. the amplitude of vibration in the pivot and tool post was the largest. ⑵ The surfaces cut by the lathe tools of intensity and stability was given periodically a regular pitch on the feed traces.