병리검사 처방오류 개선 시스템 구축

이현임,최영진,구숙희,양승주,김병로,김묘정,신일근,신미옥,서임선 한국의료QA학회 2006 한국의료질향상학회지 Vol.13 No.2

문제: 조직병리검사의 처방이 복잡하고 전문화됨에 따라 오류처방이 빈번하게 발생되고 이를 해결하기위한 프로세스가 복잡하여 부서간의 갈등과 업무의 가중, 또한 병원 수입 감소가 초래되었다. 목적: 발생된 오류처방의 유형과 발생율, 오류처방을 해결하기 위한 프로세스를 파악하여 이에 대한 문제점을 개선하여 업무의 효율성과 관련부서간의 부가업무 감소와 갈등해소, 더불어 병원수익을 향상시키는 것에 목표를 두고 활동하였다. 의료기관: 서울시에 소재한 종합병원 질 향상 활동: 조직병리검사 처방의 오류처방 발생 원인과 유형, 발생율을 조사하여 원인을 파악하고 개선을 위한 프로세스를 구축하여 질 향상을 도모하였다. 개선효과: 수술실에서 의뢰한 외과 입원환자의 일반조직병리검사 오류율은 개선 전 7.8%에서 개선 후 3.5%, 동결절편조직검사 오류율은 개선 전 28.6%에서 개선 후 0%로 이전보다 모두 개선되었다. 또한 수술실 간호사의 업무 만족도는 일반조직병리검사의 처방시 95%, 동결절편조직검사 처방시 90%로 높은 만족도를 보였다. 단 병리과의 경우 업무가 증가됨에 따라 초과근무시간이 증가하였다.

전북지역 수도수 중 잔류 알루미늄에 관한 연구

임제빈,이희보,송주훈 全北大學校 附設 都市및環境硏究所 1995 都市 및 環境硏究 Vol.10 No.1

In our country, the Ministry of Health and Social Affairs adopted the WHO standard from December 1993. However, the standards have not been monitored carefully throughout the province and there is little research on the effects of aluminum on people's health and management of cleaning bed. In this research, we measured Al in raw and treated water of major cleaning beds of chonbuk province and got the situation of contamination. The results are summarized as follows; 1. The range of the aluminum concentration in row water is from ND(non-detected) to 0.08㎎/ℓ, to average is 0.03㎎/ℓ, and it is the highest figure at 0.08㎎/ℓ in Wal-Iock bed of Nam-Won district. 2. The major concentration extent from ND to 0.009㎎/ℓ, ranks 35% and its average is 0.07㎎/ℓ. 3. When we analyzed the aluminum concentration over the passage of time, we found a lot of A1 in samples that were taken from P.M 10 to A.M.I. 4. There are no samples exceed 0.2㎎/ℓ which is the drinking water standard of WHO. 5. It is revealed that the average concentration is 0.15㎎/ℓ in big cities whose population supplied water is more than 500,000. 6. Investigating the effect on the coagulant, we knew the factors that the residual Al concentration. In the place where no coagulant was used Al concentration is 0.04㎎/ℓ on the average. The ones using the aluminum sulfate and activated carbon is 0.09㎎/ℓ on average. So the one using Al_2(SO_4)_3 is 0.11㎎/ℓ on average. 7. The concentration fluctuate with the seasons : Jenuary is 4 times as much as July. 8. It is also connected with the other water pollution the consumption of KmnO_4, NO_3-N, SO_4^2- ect.

의복구성학의 연구주제 및 경향분석

이정순,나수임,배주형 복식문화학회 2001 服飾文化硏究 Vol.9 No.2

The purpose of this study is to recognize the real situation of clothing construction to present the desirable direction to establish more scientific and reasonable themes of the study by analysis of the tendency of the clothing construction study. For this purpose, 402 papers on the theme of clothing construction study were excerpted from the first issues to the issues of December in 1999 of Journal of Korea Society of Clothing and Textile, Journal of Korea Home Economics, Journal of the Korean Society of Costume, Research Journal of the Costume Culture, Journal of the Korean Fiber Society, and Journal of the Human Engineering Society of Korea, I analyzed and classified the theme into eight issues of design related clothing construction, study of body types, study of patterns, size of apparel, fitting of clothing, protective clothing and functional clothing, sewing, and the others. The result of the study is as follows. 1. The distribution tendency of the clothing construction study by the journal of each society showed that Journal of Korean Home Economics is 22.9%, Journal of Korea Society of Clothing and Textiles 17.3%, Research Journal of the Costume Culture 12.2%, and Journal of the Korean Society of Costume 6.2%. 2. The distribution tendency of the studying issues showed that study of body types is 29.4%, study of patterns 21.9%, fitting of clothing 11.7%, sewing 10.2%, size of apparel 8.5%, and others 7%, protective clothing and functional clothing 6.7%, and design related clothing construction 4.7%. Considering the above result, we can understand that study of body types and patterns are being studied most actively. 3. Regarding the study tendency by academic issues showed that study of construction elements and design application is chiefly centered of the study of design related clothing construction (35.5%), analysis of body types is centered of the study of body types (46.6%), CAD is centered of the study of patterns (31.1%), and size spec for the ready made patterns is centered of the study of size of apparel (32.4%). As for fitting of clothing, the study was performed in two ways on the changes of the surfaces of human bodies in motion and the functional features of experimental dressing. Regarding the study of sewing, study of fusible interlining was mainly performed (36.6%) and regarding the study of protective clothing and functional clothing, study of brassieres and underwear was chiefly performed. Key words : design related clothing construction(디자인관련 의복구성), study of patterns(의복 및 패턴 연구), size of apparel(의류치수), fitting of clothing(의복의 맞음새), protective clothing and functional clothing(특수복 및 기능복).

한국의류학의 연구경향분석 : 1991~1999

나수임,이정순,배주형 복식문화학회 2000 服飾文化硏究 Vol.8 No.6

This study is planned to present the future direction of the study of Korean clothes through the realistic recognition of the changes of studying issues of each area of the related clothes. For this purpose, the writer of this thesis have collected, classified and analyzed those various kinds of papers and theses published in the professional magazines of clothes such as Journal of Korean Home Economics, Journal of the Korean Society of clothing and Textiles, Journal of the Korean Society of Costume, The Research Journal of the Costume Culture so that I might examine and study the main trend of the related study. The result of the study is as fallows. 1. Since the first publication of Journal of Korean Home Economics in 1959 and Journal of the Korea Society of Clothing and Textiles, and Journal of the Korean Society of Costume, the study of clothes has been gradually increased. Furthermore, since 1990 the issuing times of various kinds of Journals have been continuously increased with the foundation of The Research Journal of the Costume Culture and Journal of Fashion Business. 2. Theses and papers published in the four greatest Journals of Korean Clothing and Textiles have been studies for the detailed classification and analysis of the data. According to the study, It is found that the theses in Journal of the Korea Society of Clothing and Textiles have actively studied textiles as they had studied before 1990s and those in Journal of the Korean Society of Costume have studied history of costumes and those in The Research Journal of the Costume Culture have studied costumes cultures and those Journal of Korean Home Economics have studied the composition and science of clothes. 3. The order of studying subjects was 1) Design and Aesthetics, 2) Fashion Merchandising 3) Textiles, 4) Clothing Construction, 5) History of Costumes, 6) Costume Culture, 7) Socio -Psychology of clothing, 8) Others. Considering the above mentioned result of the study, most of the main fields of the clothing and textiles study have been studied continuously in balance since 1990 unlike the past although the past studies had been performed largely in some main fields only. And it was found that fields of clothing styles and clothing goods have been studied most actively since 1990s. 4. The studying field of Design and Aesthetics has showed to have the trend to be studied very actively since 1990s, which has utilized various relevant data with scholastic approach to psychology and aesthetics. Regarding Fashion Merchandising, the study of consumers decision process has been performed most actively. And theses on the international trades have been published considerably more than ever before, which resulted in gradual increase in the study of the fields related with global marketing, internet marketing, textile products exports, and overseas brands, etc. Regarding Textiles, the field of clothing sanitation and management has been studied more actively than that of clothing materials. In case of clothing construction, the study of physical styles and pattern making has been more active than the other related fields. Fields of socio-psychology of clothing and history costume have been a little reduced. Field of costume culture has been firmly rooted as an independent subject to be studied in the clothing rotated study. And study of the clothes has shown various trends of studies of ethnic & folk clothes, religious and ceremonial garments, linguistic & favorite approach to clothes and academic analysis of the data.

경고막적 및 고막외적 전극위치에 따른 와우전위의 비교연구

장동임,박철규,이병돈,장혁순,강주원 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

Electrocochleography is a method of the measurement of electrical events generated either within the cochlea or by primary afferent neurons. It includes measures of summating potential(SP) and cochlear microphonics(CM) from the cochlea, and action potential(AC) from the auditory nerve. There are severval diffefent ways to measure the potentials, mainly transtympanic and extratympanic methods. The purpose of this study is to provide a normal data of eletrocochleography in adults and compare the results obtained by extratympanic and transtympanic methods. The following results were obstained: 1. As the intensity of sound was increased, the SP amplitude and AP amplitude were increased. There was no significant difference between extratympanic and transtympanic method. 2. As the intensity of sound was increased, the SP latency and AP latency were shortened without significant difference between two different methods. 3. As the intensity of sound was increased, the SP/AP ratio was increased without difference in both methods which was less than o.30. 4. Non-invasive method of electrocohleography, the extratympanic method, can be one of the easy method an can be used widely clinically.

Glutamate 억제제가 Pilocarpine에 의한 경련 및 기억장애에 미치는 영향

천임순,한형수,박정숙,정헌주,이만기,김중영 慶北大學校 醫科大學 1996 慶北醫大誌 Vol.37 No.3

목적 : Pilocarpine에 의한 경련 및 기억력 저하에 glutamate 수용체가 관련이 있는지 검토하였다. 대상 및 방법 : 생쥐에 pilocarpine을 투여하여 야기되는 경련 및 기억력저하가 glutamate 수용체 길항 약물인 MK-801 및 NBQX를 전처치하였을 때의 반응을 Morris Water Maze의 방법으로 관찰하였다. 결과 : MK-801과 NBQX를 전처치하고 pilocarpine을 투여하였는 바 pilocarpine에 의한 경련유발은 억제되지 않았으나, pilocarpine에 의한 reference memory와 working memory의 저하는 MK-801이나 NBQX를 처치로서 억제되었다. 결론 : Pilocarpine에 의한 경련작용에 비하여 기억력저허가 glutamte 수용체와 관련이 있는 것으로 보인다. The role of glutamate receptors in the genesis of pilocarpine-induced seizure and seizure-related memory deficit was studied using MK-801 and NBQX. After pretreatment with MK-801 or NBQX, pilocarpine was administered intraperitoneally. Both drugs had no effect on the behavioral seizure activity and onset of seizure activity. Memory was tested with reference and working memory version of Morris water maze at 20th day after pilocarpine treatment. Reference and working memory deficit was produced by pilocarpine. These deficit were prevented by MK-801 or NBQX, which were given in once a day for 4 day at 7th to 10th days after pilocarpine treatment. These results show that although MK-801 and NBQX do not have anticonvulsant property they can prevent pilocarpine-induced memory deficit.

누구를 위한 POCT인가?

조경진,이창규,이승관,정희천,김미숙,남경미,전주임 高麗大學校 倂設 保健大學 保健科學硏究所 2001 保健科學論集 Vol.27 No.2

Patient-oriented minds and Bill of Rights have brought a lot of POCTs or Waived Tests, which can obviously be threats to the medical technology profession. However, we cannot help but admit the realities and should take some necessary measures to meet the situation. Accordingly we took a survey to find what opinions medical scientists or nurses have against the POCTs. Most of the scientists worried about the reliabilites of test results while nurses were concerned about the ambiguity of their job entities. Taking account of the POCT nature, the scientists should lead the development of POCT menus and have the primanry responsibility to educate or train the POCT perfomers maitaining periodic QCs on all the procedures or equimpments, not paying much attention to the issues who might be the performers.

경증 천식 환아에서 비염의 동반이 하기도 호산구 염증에 미치는 영향

한지은,이미현,송도영,강임주 대한 소아알레르기 및 호흡기학회 2004 소아알레르기 및 호흡기학회지 Vol.14 No.2

지혈제 오염이 콤포머의 전단결합강도에 미치는 영향

허정무,곽주석,이황,이수종,임미경 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.2

One of this latest concepts in bonding are "total etch", in which both enamel and dentin are etched with an acid to remove the smear layers, and "wet dentin" in which the dentin is not dry but left moist before application of the bonding primer. Ideally, the application of a bonding agent to tooth structure should be insensitive to minor contamination from oral fluids. Clinically, contaminations such as saliva, gingival fluid, blood and handpiece lubricant are often encountered by dentists during cavity preparation. The aim of this study was to evaluate the effect of contamination by hemostatic agents on shear bond strength of compomer restorations. One hundred and ten extracted human maxillary and mandibular molar teeth were collected. The teeth were removed soft tissue remnant and debris and stored in physiologic solution until they were used. Small flat area on dentin of the buccal surface were wet ground serially with 400, 800 and 1200 abrasive papers on automatic polishing machine. The teeth were randomly divided into 11 groups. Each group was conditioned as follows: Group 1: Dentin surface was not etched and not contaminated by hemostatic agents. Group 2: Dentin surface was not etched but was contaminated by Astringedent® (Ultradent product Inc., Utah, U.S.A.). Group 3: Dentin surface was not etched but was contaminated by Bosmin®(Jeil Pharm, Korea).). Group 4: Dentin surface was not etched but was contaminated by Epri-dent®(Epr Industries, NJ, U.S.A.). Group 5: Dentin surface was etched and not contaminated by hemostatic agents. Group 6: Dentin surface was etched had contaminated by Astringedent®. Group 7: Dentin surface was etched and contaminated by Bosmin®. Group 8: Dentin surface was etched and contaminated by Epri-dent®. Group 9: Dentin surface was contaminated by Astringedent®. The contaminated surface was rinsed by water and dried by compressed air. Group 10: Dentin surface was contaminated by Bosmin®. The contaminated surface was rinsed by water and dried by compressed air. Group 11: Dentin surface was contaminated by Epri-dent®. The contaminated surface was rinsed by water and dried by compressed air. After surface conditioning. F2000® was applicated on the conditoned dentin surface. The teeth thermocycled in distilled water at 5℃ and 55℃ for 1,000 cycles. The samples were placed on the binder with the bonded compomer-dentin interface paralled to the knife-edge shearing rod of the Universal Testing Machine(Zwick Z020, Zwick Co., Germany) running at a cross head speed of 1.0mm/min. Group 2 showed significant decrease in shear bond strength compared with group 1 and group 6 showed significant decrease in shear bond strength compared with group 5. There were no significant differences in shear bond strength between group 5 and group 9, 10 and 11.

Mito-Tempo Can Protect Against the Allergic Airway Inflammation through Reducing Mitochondrial ROS Generation

( So Ri Kim ),( Yong Chul Lee ),( Dong Im Kim ),( Yang Keun Rhee ),( Heung Bum Lee ),( Seoung Ju Park ),( Chi Ryang Chung ),( Seung Yong Park ),( Mi Ran Kang ) 대한결핵 및 호흡기학회 2012 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.114 No.-

Oxidative stress is well known to be implicated in the development of asthma. The mitochondrial respiratory chain is a major site of intracellular reactive oxygen species (ROS) generation and, at the same time, an important target for the damaging effects of ROS. Mito-Tempo is a specific mitochondrial ROS inhibitor and it is known to be associated with opening of mi-tochondrial permeability transition pore and inhibition of cell necroptosis or apoptosis. However, there is little information on the protective effects of Mito-Tempo on the inflammatory airway disorders including bronchial asthma and its acute exacerbation. We investigate the effects of Mito-tempo on the allergic airway inflammation and hyperresponsiveness using the mice sensitized with OVA and LPS and then challenged with OVA (OVALPS-OVA mice). The OVALPS-OVA mice showed the typical features of neutrophilic asthma; increased airway inflammatory cells, the pathologic changes, the increased levels of Th2 cytokines in lungs of OVALPS-OVA mice, increased mitochondrial ROS generation, and increased bronchial hyperresponsiveness. Interestingly, we found that in OVALPS-OVA mice, Mito-Tempo, a novel mitochondrial targeting agent significantly reduced the increases in inflammatory cytokines, mitochondrial ROS generation, airway inflammation, and bron-chial hyperresponsiveness. These findings indicate that mitochondrial dysfunction including oxidative damage may be im-plicated in the pathogenesis of bronchial asthma and provide the therapeutic potential of a mitochondrial targeting agent, Mito-Tempo, for bronchial asthma.