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      • 肝吸蟲 感染家兎에 있어서 感染强度, 經過 및 治療에 따른 ELISA抗體價의 變動에 관한 實驗的 硏究

        梁元容,李駿商,林漢鍾 고려대학교 의과대학 1984 고려대 의대 잡지 Vol.21 No.3

        Human clonorchiasis is one of the most common trmatode diseases and of very important pubic health problems in Korea. In the present study, the changing patterns of specific IgG antibody was demonstrated by the enzyme-linked immunosorbent assay(ELISA) in the sera rabbits infected with clonorchis sinensis. The O.D> (optical density) values of the ELISA in the sera were merwured according to intensity and course of infections and tendency of decrease after chemotherapy. The ELISA was performed with veronal buffered saline antigen of clonorchis, peroxidase conjugated antirabbit IgG and ortho- phenylendiamine as a substrate by micro method. In the 3 groups of rabbits infected with 50(A group), 500(B group) or 100×5(C group) metacercariae, the sera were prepared biweekly up to 18th week before chemotherapy, and biweekly up to 24th week after chemotherapy. The results were as follows: 1. O.D. values increased gradually with lapse of time before treatment. The O.D. values indicated firstly 1.000 or more in 8 weeks after infection in A group and 4 weeks after infection in both B and C groups. The O.D. values reached plateau at 10 weeks after infection in A group and 8 weeks after infection in both B and C groups. Regression equations between the O.D. values of the ELISA and period(week) after infection among 2 groups were as fllows, y=0.09x+0.319 in A group y=0.08x+ 0.826 in B group and y=0.08x+0.807 in C group. 2. The O.D. values in A group which had been treated decreased gradually and became preinfection level at 24 weeks after chemotherapy. On the contrary the O.D. values in A group which has not been treated showde plateau. The O.D. values in both B and C groups which had been cured decreased gradually and became preinfection level at 24 weeks after chemotherapy.

      • 닭의 장풀의 수경재배시 적정 pH 및 질소량 분석

        양용준,김영식 덕성여자대학교 식물자원연구소 1993 植物資源硏究誌 Vol.1 No.-

        본 연구는 닭의장풀의 생육에 미치는 배양액내 NH_4NO_3 농도와 여러 pH값의 효과를 구명함으로써 수경재배시 적합한 배양액내 적정 pH와 질소농도를 밝히는데 목적이 있으며 그 결과는 다음과 같다. 1. 생육중 배양액 pH는 생육전반기 및 배양액 교환초기(2일간)에는 상승하다가 생육후반기 및 배양액 교환 후 (3-5일간)에는 급격히 감소하였다. 2. 재배기간이 경과함에 따라 초장이 신장되고 엽수가 증가하였는데 이러한 경향은 배양액중 처리 질소농도가 높을수록 뚜렷하였다. 3. 생체중과 건물중은 생육중 크게 증가하였으나 pH값(1-6)과 NH_4NO_3 농도에 의해 영향은 인정되지 않았다. 4. Relative growth rate(RGR)는 1M일 때가 6M 보다 약간 높았으며 생육전반기가 후반기보다 높았다 5. NO_3 농도는 매주 처리후 시간이 경과할수록 감소되었는데, 6M의 pH 7에서 잔류량이 가장 높고 1M의 pH 5에서 가장 낮았다. This study was conducted to investigate the effect of NH_4NO_3 concentrations and different solution pHs on growth of Commelina communis and remaining NO_3 contents in nutrient solution. The objects of this research was to reveal the optimum pH value and nitrogen concentration in hydroponic medium. The results were summarized as follows: 1) The solution pH value tended to increase until 2 days after each medium exchange weekly and the first 2 weeks after planting, after then decreased largely. 2) Growth in plant height and development in number of leaves accelerated with adding the hydroponically cultured period and increasing the nitrogen concentration. 3) Fresh and dryweight were markedly influenced by pH values(1 or 6) and NH_4NO_3 concentrations in nutrient solution. 4) Relative growth rate(RGR) showed the highest value at 1M NH_4NO_3 concentrations in nutrient solution, and the RGR between the initial and the 3rd week was more higher than that between the 3rd and 6th week. 5) NO_3 concentration decreased slowly after the change of nutrient solution weekly. The remaining contents were highest at 6M NH_4NO_3 concentrations and pH 7 in nutrient solution.

      • 천안시 아파트 수요추정 모형구축에 관한 연구

        양승원,한용대,박근준 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

        This study attempted to address certain elements that are measurable in order forecast the growth demand for apartments in Cheon-An area. A good forecasting method needs to include both regional condition and historical trend-based data. Accordingly, this study was conducted to analyze elements of demands for apartments and develop the model of forecasting demands for apartments by using them. The main conclusions drawn from the analysis of elements related with demands for apartment in Cheon-An area are that the expectation of apartment supplies can be estimated from the model forecasting demands of apartments.

      • KCI등재

        폴록사머를 이용한 디클로페낙 고형 좌제의 개발

        용철순,오유경,김정애,김용일,박상만,양준호,이종달,최한곤 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.2

        To develop a poloxamer-based solid suppository with poloxamer mixtures, the melting points of various formulations composed of P 124 and P 188 were investigated. To investigate the effect of poloxamer to the dissolution and dissolution mechanism of diclofenac sodium from the suppository the dissolution of diclofenac sodium delivered by the poloxamer-based suppository was performed. Furthermore, to investigate the mucoadhesive property of the poloxamer-based solid suppository, the identification test in the rectum was carried out after its rectal administration in rats. The poloxamer mixtures composed of P 124 and P 188 were homogeneous. Very small amounts of P 188 affected the melting points of poloxamer mixtures. In particular, the poloxamer mixture [P 124/P 188 (97/3%)] with the melting point of about 32℃ was a solid form at room temperature and instantly melted at physiological temperature. Furthermore, very small amounts of P 188 in the poloxamer-based suppository hardly affected the dissolution rates of diclofenac sodium from the suppository. Dissolution mechanism analysis showed the dissolution of diclofenac sodium was proportional to the time. At 4 h after administration, the blue color of poloxamer-based suppository [diclofenac sodium/poloxamer mixture (2.5/97.5%)] with the P 124/P 188 ratio of (97/3%) and blue lake in the rectum was faded. However, the position of suppository in the rectum did not significantly change with time. Thus, it retained in the rectum for at least 4 h. Our results indicated that the poloxamer-based solid suppository with P 124 and P 188 would be a candidate of rectal dosage from for diclofenac sodium.

      • 다극형 스파크 �b과 다중평행판 축전기형 전송회로를 사용한 질소레이저의 동작특성

        장철용,박영수,양준목,이치원 충남대학교 기초과학연구소 1994 忠南科學硏究誌 Vol.21 No.1

        We have studied on the operational characteristics of a nitrogen laser which was coupled with a multiplex parallel capacitor type Blumlein transmission line circuit and a multiplex sparkgap. This spark gap consisted of 8 pairs of electrode and was 50 ㎝ in length, as long as the laser tube. According to increasing the number of electrodes in the spark gaps up to the 6 pairs, the output power and stability of the laser was increased. It was to be improved that the multiplex spark gap was operated as a good peformance to the nitrogen laser system. The optimum operational condition of the nitrogen laser at 20㎐ of repetition rate could be obtained with the nitrogen gas pressure of 80 torr, E/P value of 325.0 v/㎝ torr at the electrodes spacing 5.0 ㎜ and of 90 torr, E/P value of 311.1 v/㎝ torr at the electrodes spacing 6.0 ㎜ respectively.

      • SCOPUSSCIEKCI등재

        사춘기전 Ⅰ,Ⅱ급 부정교합 아동의 기도 면적, 혀의 위치와 안면 형태에 관한 연구

        황용인,이규홍,이기준,김상철,조형준,천세환,박양호 대한치과교정학회 2008 대한치과교정학회지 Vol.38 No.2

        본 연구는 사춘기 성장 이전의 I, II급 부정교합을 갖는 아동 환자들의 측모 두부 규격 방사선사진을 이용하여 두개 안면 형태를 조사하고 이들과 혀의 위치 및 면적, 기도의 면적과의 관계를 조사하여 비인두 기도 및 혀의 형태가 악골 및 부정 교합의 형태에 미치는 영향을 알아보았다. 9 - 11세의 교정환자 76명을 대상으로 측모 두부 규격 방사선사진상 ANB difference를 기준으로 대조군(I급 부정교합군: 0 ≤ ANB difference < 4.0)과 실험군(II급 부정교합군: ANB difference ≥ 4.0)으로 분류하였다. 혀 면적, 혀와 구개 사이의 면적, 비인두 기도 면적과 두개안면형태 항목을 측정하고 비교하여 다음과 같은 결과를 얻었다. 혀 면적, 혀와 구개 사이의 면적, 비인두 기도 면적은 II급 부정교합군과 I급 부정교합군 간에 유의한 차이를 보이지 않았다. Hyperdivergent안면 형태일수록 비인두 기도 면적이 좁았다. 안모의 전후방 수직 길이가 길수록 혀의 면적이 넓었고, 전안면 고경이 길수록 혀는 하방위치 하였다. 비인두기도 면적이 좁을수록 혀의 면적도 좁아졌다. 이상의 연구 결과 혀의 면적과 위치, 비인두 기도의 면적은 I급, II급 부정교합 간에 차이를 보이지 않으며 hyperdivergent 안면 형태 및 안모의 전후방 수직 길이와 관련이 있는 것으로 사료된다. Objective: This study examined the craniofacial morphology of young patients in their prepubertal stage showing class I, II malocclusion, by analyzing lateral cephalograms, and analyzed its relationship with tongue position, tongue space, and airway space in order to ascertain the effects of nasopharyngeal airway and tongue morphology on the form of the malocclusion. Methods: Seventy-six patients aging from 9 to 11 were divided into two groups depending on the ANB difference on the lateral cephalogram: Experimental grouP (CI II malocclusion group) showing 0 ≤ ANB difference < 4.0; Control group (CI I malocclusion group) showing 0 ≤ ANB difference < 4.0. The tongue space, space between palate and tongue, nasopharyngeal airway space and craniofacial morphology were compared between the two groups. Results: Tongue space, Palate-tongue space, nasopharyngeal airway space showed no significant differences between class I and class II malocclusion groups. Hyperdivergent faces were associated with smaller nasopharyngeal airway space. Longer anterior facial height and posterior facial height were associated with larger tongue space, and greater anterior facial height were associated with lower tongue position, Smaller nasopharyngeal airway space showed smaller tongue space. Conclusions: Tongue space and nasopharyngeal airway space showed no significant differences between class I malocclusion group and class II malocclusion group. Only anterior facial height and posterior facial height had an influence on tongue space and nasopharyngeal airway space.

      • 졸-겔법에 의한 Mullite 코팅막의 제조 및 특성에 관한 연구

        이용택,최영우,양중식 慶熙大學校 材料科學技術硏究所 1997 材料科學技術硏究論集 Vol.10 No.-

        출발원료로 알루미늄 세크 부톡사이드(ASB)와 테트라 에톡시실란(TEOS)을 사용하는 졸-겔법에 의해 뮬라이트 조성의 졸 용액을 제조하고, 지지체 표면위에 침지 시간의 변화에 따라 코팅을 실시하였다. 그 결과 뮬라이트 결정화를 위해서는 1,300℃이상의 열처리 조건으로 균열 없는 뮬라이트 코팅막을 제조하는 것이 가능하였으며 침지시간에 따라 코팅막의 두께가 선형적으로 증가하고 평균 기공의 크기는 20∼30Å까지 기공 제어가 가능하였다. Optimal Mullite sol was synthesized by sol-gel process using Aluminium sec-butoxide(ASB), Tetraethoxy-silane(TEOS) and then, Mullite films were dip-coated with various holding time in sol bath and heat-treated at 1300℃ above for crystallization. The thickness of coated film increased linearly with holding time in sol bath and average pore size was controllable within 20-30Å.

      • 티타늄의 산화 조건에 따른 산화막의 특성 및 인산칼슘 생성에 미치는 영향

        김인,양홍서,박연준,송호준,이용렬 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.3

        The objective of this study was to evaluate the changes of micro morphology, roughness and crystalline structure of titanium surface after various oxidation treatments. Moreover, the effect of titanium surface oxide characteristics on the formation of calcium phosphate in Eagle's MEM. Commercially pure Ti disks were treated at various thermal conditions of 530℃ (Ti-530), 600℃(Ti-600), 700℃(Ti-700), 800℃(Ti-800), 900℃(Ti-900), and 1000℃(Ti-1000), respectively, and as received cp Ti (AS-R) and passivated cp Ti (PAS) were used as comparison groups. Surface characteristics were investigated using FE-SEM, profilometer and XRD. After immersing each sample in MEM for 7days, calcium phosphate (Ca-P) formation was evaluated using FE-SEM and EDS. Crystallites of 10~30nm-size were observed on the surface of Ti-530 and Ti-600 samples. Needle-like crystals were formed on Ti-700 samples, and the crystal grain size was increased dramatically as the temperature increased higher than 800℃. The roughness of Ti-530 was higher comparing to AS-R and PAS, and the roughness decreased in the treatment range of 530-700 with dense crystalline oxide formation. However, at treatment temperatures higher than 800℃, the roughness increased and its degree was depended to the size of the crystals. The anatase structures were observed in Ti-530 and Ti-600, and anatase and rutile structures were co-existed in Ti-700 specimen. Only rutile TiO_(2) were observed in Ti-800, Ti-900 and Ti-1000 specimens. The Ca-P formation on AS-R and PAS specimens was low in MEM solution. However, the Ca-P formation was well observed on heat-treatedgroups, and its degree of formation and micro-morphology was different by the specimen groups. The crystalline and chemical structure, micro-morphology, and surface roughness of titanium were various by the conditions of heat treatments, and the grain size and crystal structure of titanium oxide affected on the degree of Ca-P formation on Ti samples in MEM solution

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