12M의 고해상도 360° 카메라를 사용한 주차장의 14면 주차 상태 판단 프로그램

이영지(Young-Ji Lee),이희열(Hee-Yeol Lee),고태영(Tae-Young Ko),곽동훈(Dong-Hoon Kwak),김재형(Jae-Hyung Kim),김주호(Joo-Ho Kim),오승진,이태윤(Tae-Yoon Lee),박상민(Sang-Min Park),이승호(Seung-Ho Lee) 대한전자공학회 2019 대한전자공학회 학술대회 Vol.2019 No.6

In this paper, we propose a program to identify 14 parking status in a parking lot using a high resolution 360° camera of 12M. The proposed program consists of three steps: Match with plane image, parking area detection algorithm, and discrimination of parking using learning method. Tests on a model car to evaluate the program to identify 14 parking status in a parking lot using a high-resolution 360° camera of 12M showed 100% accuracy for both parking and double parking. Therefore, the effectiveness of a program to identify 14 parking status in a parking lot using a high-resolution 360° camera of 12M proposed in this paper has been proved.

Comparison of the Crystallization Behavior of Silica Between Mg and Al‑Phosphate Used in Tension Coatings of Grain‑Oriented Electrical Steel

Hyung‑Ki Park,Min‑Soo Han,Chang‑Hwan Chang,Jong‑Tae Park,박창수,Hyung‑Don Joo 대한금속·재료학회 2020 METALS AND MATERIALS International Vol.26 No.3

The effect of the phosphate component on the thermal stability of tension coatings was investigated with a focus on thecrystallization behavior of amorphous silica in the tension coating. After stress-relief annealing, core loss of samples coatedwith a Mg-phosphate was improved, while that coated with an Al-phosphate was deteriorated. The domain wall spacing ofthe samples coated with Mg- and Al-phosphates was respectively increased and decreased after stress relief annealing. Thismeans that the stress relief annealing did not much diminish the tensile stress for Mg-phosphate coating but much diminishedthe tensile stress for Al-phosphate coating. Based on FTIR and XRD results, we found that the crystallization temperatureof silica with Al-phosphate was lower than that of silica with Mg-phosphate. The crystallization of silica was accompaniedby an abrupt volume change, which formed cracks in the tension coating and deteriorated the tensile stress.

C-reactive protein accelerates DRP1-mediated mitochondrial fission by modulating ERK1/2-YAP signaling in cardiomyocytes

( Suyeon Jin ),( Chan Joo Lee ),( Gibbeum Lim ),( Sungha Park ),( Sang-hak Lee ),( Ji Hyung Chung ),( Jaewon Oh ),( Seok-min Kang ) 생화학분자생물학회 2023 BMB Reports Vol.56 No.12

C-reactive protein (CRP) is an inflammatory marker and risk factor for atherosclerosis and cardiovascular diseases. However, the mechanism through which CRP induces myocardial damage remains unclear. This study aimed to determine how CRP damages cardiomyocytes via the change of mitochondrial dynamics and whether survivin, an anti-apoptotic protein, exerts a cardioprotective effect in this process. We treated H9c2 cardiomyocytes with CRP and found increased intracellular ROS production and shortened mitochondrial length. CRP treatment phosphorylated ERK1/2 and promoted increased expression, phosphorylation, and translocation of DRP1, a mitochondrial fission-related protein, from the cytoplasm to the mitochondria. The expression of mitophagy proteins PINK1 and PARK2 was also increased by CRP. YAP, a transcriptional regulator of PINK1 and PARK2, was also increased by CRP. Knockdown of YAP prevented CRP-induced increases in DRP1, PINK1, and PARK2. Furthermore, CRP-induced changes in the expression of DRP1 and increases in YAP, PINK1, and PARK2 were inhibited by ERK1/2 inhibition, suggesting that ERK1/2 signaling is involved in CRP-induced mitochondrial fission. We treated H9c2 cardiomyocytes with a recombinant TAT-survivin protein before CRP treatment, which reduced CRP-induced ROS accumulation and reduced mitochondrial fission. CRP-induced activation of ERK1/2 and increases in the expression and activity of YAP and its downstream mitochondrial proteins were inhibited by TAT-survivin. This study shows that mitochondrial fission occurs during CRPinduced cardiomyocyte damage and that the ERK1/2-YAP axis is involved in this process, and identifies that survivin alters these mechanisms to prevent CRP-induced mitochondrial damage. [BMB Reports 2023; 56(12): 663-668]

중증 객혈환자의 구명을 위한 새로운 외과적 접근 : 흉골 정중절개에 의한 폐엽의 기관지-혈관 격리술

박형주,이철세,고정관 순천향대학교 1994 논문집 Vol.17 No.4

Major hemoptysis is not only a clinical challenge but also the most critical situation when it is aspirated into the tracheobronchial tree especially in the chronic debilitated patients. Recently, bronchial artery embolization(BAE) is the most effective measure for the primary conservative management and salvages a lot of lives in the emergency situations. However, as the recurrence rate of hemoptysis after embolization is significant and there are very poor cases that cannot be controlled by every medical efforts, emergency surgical resection is the only way of lifesaving. In these high risk group of patients, standard lobectomy resulted in high mortality and morbidity. Since October, 1993, we introduced a new surgical approach of "Broncho-vascular Isolation Lobectomy" for the lifesaving of medically failed life-threatening hemoptysis. Now we report 3 cases treated by this approach and would like to suggest future implications in the treatment of major hemoptysis.

쿠싱 증후군 환자에서의 당대사 이상

박형주,박중열 대한내분비학회 2003 Endocrinology and metabolism Vol.18 No.4

마약길항제의 방출 제어형 제제 (제1보) : 생체분해성 polyphosphazenes의 합성과 나록손 이식제제의 제조 및 용출특성 Synthesis of Biodegradable Polyphosphazenes and Preparation and Release Characteristics of Naloxone Implant

박주애,이승진,김형국,김길수 梨花女子大學校 藥學硏究所 1995 藥學硏究論文集 Vol.- No.5

For the administration of narcotic antagonist with short half-life and low patient compliance. the sustained release system using biodegradable matrix is effective. Polyphosphazenes are of considerable interest as biodegradable matrix systems for controlled release of drugs. In this study. biodegradable polyphosphazenes available for the sustained release implantable device were synthesized. and their application was examined. Poly〔dichlorophosphazene〕 was synthesized by solution polymerization method and confirmed with IR spectrum. Poly〔bis(ethyl glycinate) phosphazene〕 and poly[(diethyl glutamate)-co-(ethyl glycinate)phosphazene] were then produced by substitution of amino acid alkyl esters for chloride side groups. Using these polymers. the implantable devices of 1 ㎜ thickness and l0 × 10 ㎜ size containing naloxone hydrochloride were prepared and their release and degradation profiles were measured. In the case of poly〔bis(ethyl glycinate)phosphazene〕 with swelling characteristics, degradation rate was slower than the release rate, showing that the release rate is partly dependent on the swelling rate. In contrast, the degradation rate of poly〔(diethyl glutamate)-co-(ethyl glycinate)phos-phazene〕 matrix was identical with release rate of naloxone hydrochloride. On the basis of these results, it is expected that these polymers can be applied to sustained release implantable systems delivering narcotic antagonist.

3kW 태양광발전시스템의 실증시험(Ⅰ)

박정민,조금배,백형래,최창주 조선대학교 에너지.자원신기술연구소 2004 에너지·자원신기술연구소 논문지 Vol.26 No.1

Consider the optimal design for PV system, it is apply to 3㎾ interconnected electric power PV system, that is a point of reference for 3㎾ PV the spread residential section system. Through the driving various practical system, we look into that fbr efficiency of generation and stability of interconnected system. Using obtained data acquisition, It can be suggest that installation and management for system parameter to optimal design maximum generation electric power. PV system have some losses that are variation radiation, shadow, change temperature, unbalanced grid connection, serial circuit loss, MPP deference loss, PCS loss and so forth. Using obtained various performance characteristic result, we can make database in the future, through the this study, we can get the reliance and have regard to spread PV system.

시멘트 콘크리트의 건조수축균열 특성

박제선,윤경구,이주형,김태환,정원경 강원대학교 부설 석재복합신소재 제품연구센터 2000 석재연 논문집 Vol.5 No.-

콘크리트는 본질적으로 인장강고와 휨강도가 약하며 취성적 성질을 나타내는 결점을 가지고 있으므로 이를 보강할 목적으로 콘크리트에 섬유를 혼입한 섬유보강 콘크리트가 크게 각광받고 있다. 특히 폴리프로필렌 섬유보강은 모르타르 및 콘크리트가 건조나 동해에 의해 수축될 때 구속에 의해 발생되는 인장응력 및 균열을 제어하고 인성의 증가와 충격, 마모, 피로에 대한 저항성, 내구성을 증대시키는 장점을 가지는 것으로 보고 되고 있다. 1축으로 구속된 건조수축의 구속으로 인한 조강형 콘크리트의 잔류응력을 선형모델을 이용하여 예측할 수 있었고 조강형 콘크리트에 섬유보강으로 인한 건조수축 제어효과는 일반큰코리트에 비해 효과가 매우 큰 것으로 나타났다. 따라서 폴리크로필렌 섬유의 혼입으로 인해 콘크리트의 균열제어가 가능하며, 균열 폭이 큰 균열보다는 많은 미세 균열을 유도하는 것을 알 수 있었다. 섬유보강 조강형 큰크리트의 동결융해저항특성은 거의 동해의 손상을 받지 않으며 좋은 내구성을 유지하고 있는 것으로 나타났다. 이는 불규칙하게 배향된 섬유가 공극수의 이동을 효과적으로 제어함으로써 메트릭스 내의 팽창압으로 인한 파괴를 최대한 줄였기 때문이라고 보여진다. 표면손상과 박리저항에 매우 우수하며 저항성을 증진시키는 효과가 뛰어남을 확인할 수 있었다. 따라서, 내구적 측면의 유지, 보수에 있어서도 섬유보강은 그 효과가 큰 것으로 나타났다. To improve the brittle nature of concrete, discrete fibers can be adapted in concrete. Since polypropylene fiber has many advantages in many points on its chemical stability and good durability, its usages have been increased gradually. It has been reported than polypropylene fibers can not only control restrained tensional stresses and cracks, but also increase toughness, resistance to impact, corrosion, fatigue, and durability. Although the polypropylene fiber reinforced concretes with ordinary cement have been studied so much, those with very early strength concretes have not studied at all. Therefore, it is necessary to initiate and conduct the researches for the polypropylene fiber reinforced very early strength concretes which has enough workability and durability. This study of polypropylene fiber reinforced very early strength concrete focused on the investigation each material's effect into strength development with analysis of restrained shrinkage properties with one-dimensional concrete members. The results showed that more optimized mixture combinations could be selected in very early strength concrete by incorporating polypropylene fibers, keeping in same strength levels at urgent repair works. The formation of needle-shape ettringite helps the early strength development, specially at flexural and this enables the repaired concrete structures or pavements to be opened to traffic after 3 hours of concrete placement. A residual stress of early strength concrete caused by one-dimensional restrained drying shrinkage was predicted from linear model. the control of shrinkage crack by fiber reinforcement at early strength concrete was better than that of ordinary portland cement concrete because of bridging effect of fiber at early age and resulting of more hair cracks rather than fewer wider cracks. As a results, this dissertation clearly validated the fiber reinforcement on the strength development and durability of polypropylene fiber reinforced very early strength concrete, and characteristic of restrained shrinkage. The proposed optimized concrete mixtures might be satisfactory applied at the repair works in fields, because of its durability and crack control capacity against freeze-thaw and contraction at early age, respectively.

폐타이어로 성형제조된 부정형 과립담체에 부착된 미생물의 측정방법

박종웅,송주형 대한상하수도학회 2003 상하수도학회지 Vol.17 No.2

This study was carried out to know the physicochemical properties and determine the measurement method of attached biomass in irregular shape granular (ISG) media molded with waste tire. The size of ISG media and specific surface area were Φ4-10㎜ and 0.00412㎡/g, respectively. The using of pretreatment agents as 0.8N CuSO_4-0.7N Sulfamic acid was proper to prevent self-oxidation of attached biomass on ISG media. The detaching method of attached biomass in ISG media was suitable for conducting ultrasonic and alkali treatment at the same time. The optimum alkali concentration and washing time were 0.125N NaOH and 120min, respectively. Finally, it was concluded that the result of this study could be establishing as a measurement method of attached biomass on ISG media molded with waste tire.

셀레콕시브 및 그 합성유도체들의 항암활성 스크리닝

박정란,강진형,구효정,노지영,류형철,박상욱,고동현,조일환,이주영,황다니엘,김인경 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.2

Selective COX (cyclooxygenase)-2 inhibitors including celecoxib have been shown to induce apoptosis and cell cycle changes in various tumor cells. New inhibitors are recently being developed as chemomodulating agents. We evaluated celecoxib and screened 150 synthetic compounds for anti-proliferative activities in vitro. Effects of celecoxib on COX activity, cell growth, cell cycle distribution, and apoptosis induction were determined in A549 COX-2 overexpressing human non-small cell lung cancer (NSCLC) cells. The COX inhibition of celecoxib increased with concentration up to 82% at 1μM after 24 hr exposure. Forty μM and 50μM of celecoxib induce G_1 arrest, and TUNEL-positive apoptotic cells, respectively. Among 150 compounds, several compounds were selected for having greater COX-2 inhibitory activity and higher selectivity than celecoxib with growth inhibitory activity. Celecoxib showed concentration-dependent COX inhibitory activity, and ability to induce cell cycle arrest and apoptosis in human NSCLC cells in vitro. Among synthetic analogues screened, several compounds showed promising in vitro activity as COX-2 inhibitory anticancer agents, which warrant further evaluation in vitro and in vivo.