DDC,MEA,WR-2721의 放射線 防護效果에 關한 硏究

柳星烈,陳秀一,鄭鉉佑,鄭引溶,高柱煥,고경환 대한방사선 방어학회 1986 방사선방어학회지 Vol.11 No.2

放射線障害 豫防藥劑의 人體適用은 副作用으로 臨床的 利用이 되지 못한 實情으로서 生理學的 및 藥理學的 毒性, 物理學的 諸性質, 藥劑의 作用機轉究明 및 臨床的 技術開發이 未洽하여 放射線 障害者에 對한 治療는 對症療法에 不過한 實情이다. 著者들은 放射線에 依한 人體障害豫防에 必要한 基礎資料를 얻기 위하여 現在까지 比較的 毒性이 적고 化學的으로 安定하며 藥效가 優秀하다고 알려진 DDC, MEA, WR-2721을 選定하여 實驗動物 非近交系 Swiss Webster(NIH-GP)마우스에 利用한 放射線 防護作用에 關한 實驗結果는 다음과 같다. 1) 各種 放射線 防護劑(DDC, MEA, WR-2721)의 마우스에 대한 適定 投與量은 各各 DDC; 1,000, MEA; 200, WR-2721; 400mg/kg이었다. 2) 實驗動物에 放射線 反致死線量 LD50/10에 對한 藥劑의 防護效果을SMS DDC;1.2, MEA; 1.4, WR-2721; 1.9이었고 LD50/30에 對 한 DMF는 DDC; 1.7, MEA; 1.8, WR-2721; 2.5이었다. 3) 空腹 小?腺(Jejunum crypt)의 放射線平均致死線量(Do)에 對한 防護效果 DMF는 DCC; 1.07, MEA; 1.21, WR-2721; 1.76이었고, 小?腺細胞의 致死線 平均致死線量에 對한 DMF는 DDC; 1.04, MEA; 1.08, WR-2721; 1.38이었다. 4) 以上으로 上記 3種의 放射線 防護劑中 WR-2721의 放射線 防護效果가 가장 優秀하였고 이 結果는 向後 臨床的 適用에 關한 硏究의 基礎資料가 될 것으로 思料된다. At present, the treatments of the radiation-induced diseases are only performing by the palliative treatment technique. Moreover, radiation protective agents are a little toxic for human being and this seriously limits their applicability with various complications in clinical uses. Accordingly, as a part of the aim of gain of the basic data for protective roles of some radioprotectors, the present investingation was carried out to evaluate the comparative radioprotective effects by the administration of DDC, MEA, WR-2721. Results are shown for statistically significant analysis and correlation with each group as follows; 1. The proper doses of the radioprotectors were DDC; 1,550mg/kg, MEA; 450mg/kg, WR-2721; 780mg/kg of the mouse body weight. 2. DMF(Dose modification factor) of LD50/10 and LD50/30 for whole body irradiation was DDC; 1.2, MEA; 1.4, WR-2721; 1.9 and DDC; 1.7, MEA; 1.8 and WR-2721; 2.5 respectively. 3. DMF for radiation reaction of jejunal crypt was DDC; 1.07, MEA; 1.21 and WR-2721; 1.76 and that of jejunal crypt cell was DDC; 1.04, MEA; 1.08 and WR-2721; 1.38 respectively. 4. Conclusively, WR-2721 was the most effective drung among the three radioprotectors and this result must be a supportive data for further study for clinical application.

청소년의 부모 양육행동 지각과 학교적응과의 관계

유안진,이점숙,서주현 한국가족관계학회 2004 한국가족관계학회지 Vol.9 No.3

This study was to investigate adolescents' perception of parenting behaviors and adolescents' school adjustment by their sex and age. Also, this study examines the relationships between those two variables. The subjects were 3586 middle and high school students who live in Seoul and Incheon. All respondents answered by self-report questionnaire. Data were analyzed by two-way ANOVA, t-test, and Pearson's correlations. The major findings were as follows. First, adolescents' perception of parenting behaviors was significantly different depending on their sex and age. Second, adolescents' school adjustment was significantly different depending on their age, not on sex. There was an interaction effect by sex and age on the rule adjustment. Third, there were significant correlations between adolescents' perception of parenting behaviors and their school adjustment.

준설토의 건조수축에 의한 강도증가 특성과 지지력에 관한 연구

유남재,이종호,이명욱,김현주 강원대학교 산업기술연구소 2000 産業技術硏究 Vol.20 No.A

This research is results of experimental and numerical works on characteristic of strength increase and bearing capacity in dredged and reclaimed soil due to desiccation shrinkage. For a soil sampled from southern coastal area in Korea, basic soil property tests and standard consolidation test with falling head permeability tests were carried out to obtain consolidational characteristics of soil. Double cone penetration test. laboratory vane test and unconfined compression test were also performed to investigate the change of shear strength with degree of desiccation. Model tests were performed in 1G environment and 30G level artificially accelerated condition by using the centrifuge model test facilities to investigate the bearing capacity of desiccated ground. Test results were analyzed by using the bearing capacity of desiccated ground. Test results were analyzed by using the theoretical and load-settlement characteristics method proposed by Meyehof & Hanna(1978). On the other hands, the numerical technique, using the finite strain consolidation theory considering the effect of desiccation was used to estimate the appropriate time of using heavy construction equipments in field with respect to strength increase due to desiccation.

수학적 사고의 교수방법으로서의 수학화

유현주 全州敎育大學校 科學敎育硏究所 1997 科學 敎育 硏究 論文集 Vol.19 No.1

Researchers have insisted that mathematics should be learned not as a product but as a process. Nevertheless school mathematics has chosen 'top-town' method and has usually instilled into the mind of students the mathematical concepts in the form of product. Consequently school mathematics has been learned by students without the process of inquiring and mathematical thinking. According to Freudenthal, it is a major source of all problems of mathematical education. He suggested mathematising as the method for "teaching to think mathematically" "Teaching to think mathematically" through the process of mathematization, interpreting and analysing mathematics as an activity, is a means to embody the purpose of mathematics education.

재발성 류마티즘 환자에서 발작의 유발인자

주유철,이동민,양종태,신병철,임태영,서정균,정기영,최동헌,김원,조영신,고희관 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Background and Objectives : Palindromic rheumatism (PR) is known to be triggered without any obviously inciting events in most patients, although, in a few cases, attacks have been noted to relate to another events such as weather change, childbirth, ingestion of certain foods, or over-exercise. The aim of this study was to characterize the triggering factors on palindromic attacks. Materials and Methods : We evaluated sixty-four patients with PR for the presence of triggering factors and the relationship between attacks and triggering factors by interview of patients. We considered that there was an probable association between episodes and PR, if episodes within 24 hours prior to PR had triggered at least 50% of all attacks and a definite association between episodes and PR, if episodes within 24 hours prior to PR had triggered 100% of all attacks. Results : In 15 patients (35.9%), there was a possible association between episodes of PR and initiating events. In 8 patients (12.5%), there was a definite association between episodes of PR and initiating events. The triggering factors were physical over-activity including exercise (19/64: 29.7%), foods, such as rawfish, crab, and chicken, including alcohol (19/96: 19.8%). However, there were no difference between the groups with and without the triggering factor in sex ratio, duration and onset of PR, the positive rate of rheumatoid factor and involved sites. Conclusion : Our observations showed that PR was triggered by physical over-activity more than in previous reports and hypersensitivity to foods was a causative factor in some patients with PR. However, patients with triggering factors had a similiar clinical profile to patients without triggering factors.

중학교 가정과 교수-학습 방법의 개선을 위한 집단탐구 수업모형의 적용연구

남현주,유태명 한국 가정과 교육 학회 1996 한국가정과교육학회지 Vol.8 No.2

This study was to develop and to suggest a lesson plan for the area of 'Human Development and Family Relationship' in home economics for junior high school, based on Thelen's'Group Investigation Model', Group investigation model by Thelen was developed from the theory that the education with special purpose such as societic knowledge is a method to lesson one's conflict. This study further developed from three main concepts : inquiry, knowledge and activities of learning group. This model can be used for any age and any subjects in order to solve the arised problems, rather than to accept pre-organized and pre-decided information. This study is organized around activities for seeking and practicing the rages of action to create dispersal home. First, one unit 'Understanding of Family' was chosen that concerns and suitable for group investigation model Second, From the chosen chapter and problem were analyzed organized. Third, the chosen problem were re-analyzed, then a model lesson for group investigation was proposed.

Forward Scattering Meter 측정에 의한 부산의 하계 시정 특성

김유근,배주현,이수현 한국환경과학회 2000 한국환경과학회지 Vol.9 No.5

Visibility reduction is a barometer of air pollution, which people can notice easily. First of all, we need to measure quantified visibility continuously in order to examine visibility reduction. Prevailing visibility is not practical to measure visibility depending on observer's expertness. Scattering visibility using Forward Scattering Meter (Belfort Visibility Sensor 6230) has been measured at Kwangan-Dong in Pusan and analysed since July, 1998. According to the analysis, the correlation coefficient(R) between prevailing visibility and scattering visibility was 0.7235. The visibility appeared that each frequency of poor visibility (under 6㎞) and good visibility(over 25㎞) was 10.6%, 9.7% on summertime in Pusan and the visibility range from 10km to 20km ranked high frequency as a half of whole ranges. The order of correlation coefficients between visibility and air pollutants are ranking CO, PM_10 and NO_2, that values are 0.5878, 0.5369, 0.5284 respectively. In meteorological factor, the case of poor visibility presented more weakly wind speed and higher relative humidity than the case of good visibility. The correlation coefficient between calculated visibility of multiple linear regression model and observed visibility was 0.7215. But the trend of calculated and observed visibility variation was similar with the exception of several good visibility cases.

자동 경계 탐지(Automated Border Detection)심초음파도를 이용한 좌심방 면적 및 기능의 평가

김현주,주승재,임진형,정효균,이영수,유호대,차태준,이재우 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.2

광원의 종류에 따른 복합레진의 중합거동 및 중합률에 관한 연구

류주희,이인복,유현미,김미자,석창인,권혁춘 大韓齒科保存學會 2004 Restorative Dentistry & Endodontics Vol.29 No.4

Objectives: The purpose of this study was to observe the reaction kinetics and the degree of polymerization of composite resins when cured by different light sources and to evaluate the effectiveness of the blue Light Emitting Diode Light Curing Units (LED LCUs) compared with conventional halogen LGUs. Materials and Methods: First, thermal analysis was performed by a differential scanning calorimeter(DSC). The LED LCU (Elipar Freelight, 320㎽/㎠) and the conventional halogen LCU (XL3000, 400㎽/㎠) were used in this study for curing three composite resins (SureFil, Z-250 and AEliteFLO). Second, the degree of conversion was obtained in the composite resins cured according to the above curing mode with a FTIR. Third, the measurements of depth of cure were carried out in accordance with ISO 4049 standards. Statistical analysis was performed by two-way ANOVA test at 95% levels of confidence and Duncan's procedure for multiple comparisons. Results: The heat of cure was not statistically different among the LCUs (p > 0.05). The composites cured by the LED (Exp) LCUs were statistically more slowly polymerized than by the halogen LCU and the LED (Std) LCU (p< 0.05). The composite resin groups cured by the LED (Exp) LGUs had significantly greater degree of conversion value than by the halogen LCU and the LED (Std) LCU (p = 0.0002). The composite resin groups cured by the LED (Std) LGUs showed significantly greater depth of cure value than by the halogen LCU and the LED (Exp) LGU (p < 0.05).

부산지역 시정악화의 원인 분석

김유근,문윤섭,배주현,곽진 한국환경과학회 1999 한국환경과학회지 Vol.8 No.6

After analyzing the correlation between air pollution and visibility, TSP and NO_2 is responsible for poor visibility in Pusan. After analyzing the correlation between meteorological factors and visibility, general pattern of humidity has clear negative correlation. The variation of wind speed has a positive correlation. In order to investigate the cause of poor visibility in Pusan area, the Andersen sampler and PM-2.5 are used to collect and analyze aerosol. This study was carried out to monitor the visibility using Forward scattering meter and to find out the characteristics and the cause of good visibility case and poor visibility case by measuring and analyzing a variety of parameters, such as particle size distributions, chemical compositions, and meteorological conditions in Pusan. According to the analysis of intensive sampling, NO_3^-, NH_4^+ ion concentration increased together with the mass concentration around 0.5∼2.5㎛ approximately during the case of poor visibility. NH_4NO_3, NH_4Cl, and NaCl were thought to be the major components of fine particles.