The Reactions of O(3P) Atom with Halomethanes:Discharge Flow-Chemiluminescence Imaging Method

Jee-YonLee,Hee-SooYoo 대한화학회 2002 Bulletin of the Korean Chemical Society Vol.23 No.2

reaction by oxygen atom from bromine orchlorine substituted methanes are known to be 5 orders ofmagnitude slower than reaction 6.6 The rate of reaction 7 inthis work is much faster than that of CH3Br + O.5,6 The OBror OH formation pathway in the reaction 7 is not feasible atroom temperature since the pathways are estimated to behighly endothermic by comparing the reaction CF2HBr +- kw kbia + ( )294 Bull. Korean Chem. Soc. 2002, Vol. 23, No. 2 Jee-Yon Lee and Hee-So YooO(1D).12 No kinetic and thermodynamic data are availablefor CHCl2Br and its reaction with O(3P). The thermo-dynamically possible pathways which enhance the overallreaction, not accounting the spin conservation, could beproposed by comparing the CF2HBr + O(1D) as reactions 7a-7f:CHCl2Br + O(3P) CCl2O + HBr (7a)CHCl2Br + O(3P) CCl2O + H + Br (7b)CHCl2Br + O(3P) CHClO + BrCl (7c)CHCl2Br + O(3P) CHClO + Br + Cl (7d)CHCl2Br + O(3P) CHCl2O + Br (7e)CHCl2Br + O(3P) CO + HCl + BrCl (7f)Acknowledgment. This work was supported by grantnumber BSRI-01-5 from Basic Science Research Institute,Chungbuk National University.

흰쥐 Kupffer 세포에 대한 Propofol의 작용

박세훈,지대림,성언기,김희선,송인환,박희영,김준수,이덕희,박대팔 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.43 No.4

Background: Propofol has an antioxidant capacity and can be used for ischemia-reperfusion injury of the liver. However, the effects of propofol on the Kupffer cells have not been establisked. Methods: Kupffer cells were isolated and cultured from male Sprague-Dawley rats. The effects of propofol on the Kupffer cells were evaluated by a phagocytosis assay, TNF-α gene expression, and superoxide anion release after administering propofol in different concentrations on the cultured Kuprrer cells. Results: The latex bead phagocytosis by the Kupffer cells was suppressed when the Kupffer cells were exposed to propofol irrespective of concentrations. Higher propofol concentrations decreased the loss of Kupffer cells after latex bead phagocytosis. Propofol induced TNF-α mRNA expression in the Kupffer cells, but the mRNA expression level after 50㎍/ml of propofol decreased. The pattern of TNF-α mRNA expression induced by propofol was different to that induced by LPS: TNF-α mRNA was expressed continuously in the propofol-treated cells until 16 hours after exposure to propofol, whereas the level of TNF-α mRNA expression induced by LPS was evident after 2 hours and was not found thereafter. TNF-α production after propofol treatment was not higher than that of the control. Formazan presipitation did not show any qualitative differences between cells untreated or treated with propofol concentrations of 0.5, 5.0, and 50 ㎍/ml. Conclusions: These results showed that propofol might inhibit Kupffer cells. This suggests that propofol and be used for patients with ischemia-reperfusion injury of the liver. (Korean J Anesthesiol 2002; 43: 475~484)

The Time Course Effects of Conjugated Linoleic Acids on Body Weight, Adipose Depotsand Lipid Profiles in the Male ICR Mice Fed Different Fat Sources

Hwang, Yun Hee,Kang, Keum Jee 덕성여자대학교 대학원 2005 덕성여자대학교 대학원 논문집 Vol.7 No.-

This study examined the time course effects of conjugated linoleic acids(CLA) on the body weight, lipid depots and lipid profilesof ICR male mice using two different sources of fats in the diet. Ninety eight mice weighing 25 to 30g were divided into four groups: beef tallow (BT) and fish oil (FO), beef tallow with CLA supplementation (BTC), and fish oil with CLA supplementation (FOC) group. Eight to nine mice in each group were fed with the experimental diets for 1,2 or 4 weeks, respectively. All mice were fed experimental diets containing 12% of total dietary fat (w/w) with or without 0.5% CLA (w/w). CLA supplementation did not affect the body weight. The weight of epididymal and visceral fats were significantly lower in BTC compared to those in BT groups during the periods examined (p<0.05), whereas they were significantly lower in FOC than those in FO only at 4 weeks (p<0.05). The levels of triglycerides in the plasma were significantly decreased in the BTC group than in BT group throughout the experimental periods (p<0.05). But, FOC was only effective at 4 weeks as compared to FO. The levels of total cholesterol and HDL-C weresignificantly increased in the BTC than in BT during the entire period (p<0.05), whereas there were no difference between FO and FOC on the levels of total cholesterol and HDL-C. The levels of free fatty acids (FFA) were significantly decreased in BTC than in BT at 1 and 4weeks and in FOC only at4 weeks as compared to FO (p<0.05). Taken these results together, CLA was more effective in the beef tallow diet in lowering the epididymal and visceral fat weights and triglyceride level rather than fish oil diet with CLA. Furthermore, the effect became clearer at 4 weeks than at one week of the experiment.

쑥 급여 돼지고기의 냉장저장 중 품질특성

김일석,진상근,송영민,하경희,김회윤,남기윤,류현지,하지희 한국국제농업개발학회 2004 韓國國際農業開發學會誌 Vol.16 No.4

쑥 분말 사료를 암돼지 및 거세돈에 첨가하여 그 수준에 따라 0%(T1, 암돼지, T2; 거세돈)와 1.5%(T3; 암돼지, T4, 거세돈)로 각 구별 45두씩 배치, 42일간 급여하여 생산된 돈육의 육질특성은 다음과 같다. 도체중량과 등지방두께는 73가 가장 낮았으며, 도체등급에서는 처리구간 유의차가 없었다(P>0.05). 쑥 분말 급여시 암돼지간(T1과 T3)에서는 조회분, 거세돈간(T2와 T4)에는 조지방 및 조회분 함량이 유의적으로 증가하였다(P<0.05). pH는 저장기간에 증가함에 따라 모든 처리구에서 감소하였으며, 쑥 분말 급여 처리구(T3와 T4)에서다소 높은 pH값을 나타내었다 드립감량은 처리구간에 일정한㎏/㎠경향을 나타내지 않았지만 저장기간이 경과함에 따라 높아졌다. 전단가(shear force, ㎏/㎠)는 T1을 제외한 모든 처리구에서 저장기간이 길어짐에 따라 감소하였다. 명도와 적색도는T3가 T1 보다 다소 높은 수치를 보였으나, 거세돈간(T2와 T4)에서는 오히려 낫게 나타났다. 저장기간이 증가함에 따라 TBARS와 VBN값은 공히 유의적으로 증가하였으며(P<0.05),쑥 분말 급여 처리구(T3 및 T4)에서 유의적으로 더 높게 나타났다(P<0.05). 지방산 분석결과, 포화지방산(saturated fatty acids)은 대조구에 비해 쑥 분말 첨가수준 증가에 따라 포화지방산은 높아지고 상대적으로 불포화지방산(unsaturated fatty acids)은 낮아지는 경향이 있었으나 유의차는 없고, 콜레스테롤의 경우에도 동일하게 유의적인 차이가 없었다. 전체적인 기호도는 신선육 및 조리육 공히 처리구가 낮은 점수를 얻었다. 향후 쑥 분말 급여에 대한 보다 많은 연구가 진행되어야 할 것으로 판단된다. This study was carried out to investigate the feeding effects of mugwort powder on meat quality characteristics for 42 days. The results obtained were as follows; Carcass weight(㎏) and backfat thickness(㎜) of T3 showed the lowest compared with other treatments. Grade scores were not significantly differ among the all treatments. In the proximate composition, crude ash content was higher(P<0.05) in the T3 than that of T1, while, crude fat and crude ash contents in T4 were higher(P<0.05) than those of T2. pH values were tended to low as storage period extended, in particular, those values slightly higher in the T3 and T4. Drip loss(%) was tended to increase during storage. Shear force(㎏/㎠) in all samples showed the decreased during the storage, except for Ti. L^(*) and a^(*) of T3 were slightly higher than those of T1, while, T4 was lower than T3. TBARS and VBN of all samples were significantly increased(P<0.05) as storage period extended, those values significantly higher(P<0.05) in the T3 and T4. There were no differences in saturated fatty acids, unsaturated fatty acids and cholesterol of pork meat between control(T1 and T2) and treatments(T3 and T4). The sensory score of pork samples fed with mugwort power were lower than that of control(T1 and T2) in both fresh and cooked meat. Further studied are needs on the pigs fed with mugwort powder.

Hepatic Cirrhosis Occurring in a Young Woodchuck(Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus(WHV)

Kyu-shik Jeong,정원일,Jae-yong Chung,Mi-young An,Chae-yong Jung,Gyoung-jae Lee,Jong-soo Kang,Byeong-cheol Kang,Young-heun Jee,Bruce H Williams,Young-oh Kwon,Da-hee Jeong 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

Cirrhosis Occurring in a Young Woodchuck (Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus (WHV)Da-hee Jeong, Won-il Jeong, Jae-yong Chung, Mi-young An, Chae-yong Jung, Gyoung-jae Lee1, Jong-soo Kang1, Byeong-cheol Kang2, Young-heun Jee3, Bruce H Williams4, Young-oh Kwon5 and Kyu-shik Jeong*College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea1Shinwon Scientific Co., LTD, Research Institute, Suwon, Korea2Clinical Research Institute, Seoul National University, Seoul 110-744, Korea3College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea

C_57BL/6계 생쥐와 Nude계 생쥐의 오금림프절내 림프소절 및 종자중심의 분포에 관한 3차원적 연구

지연근,이원규,안희경 慶熙大學校 1992 論文集 Vol.21 No.-

This study was aimed to clarify the distribution of lymph follicles and germinal centers in the lymph nodes of the C_57BL/6 and nude strain mice. Male adult mice were used in this study. After animal were sacrificed, the right popliteal lymph nodes were removed and fixed in Zenker-formol solution for 3 hours and embedded in JB-4 resin. One of every two section, cut 3㎛ in thickness serially, was stained with May-Gru‥nwald and Giemsa solution. The results obtained from this study were as follows; 1. The number of lymph follicles per popliteal lymph node was average 11.25 C_57BL/6 mice but, the number of lymph follicles in nude mice was 20.25. In C_57BL/6 mice major distribution(8.5) of the lymph follicles situated in peripheral cortex overlying the unit(PCOU). In unde mice major distribution(14) is peripheral cortex beyond the unit(PCBU). 2. The thickness of most lymph follicles was between 0.01-0.19 mm in C_57BL/6 mice. But in nude mice the thickness of most of lymph follicles was between 0.20-0.39mm 3. The number of lymph follicies contained germinal center was 8.75 in nude mice. But C_57BL/ 6 mice was not observed germinal centers. 4. The average number of deep cortex is 1.5 and shape is semiovoid in C_57BL/6 mice. Spherical shaped deep cortex was observed and the number of that is one in nude mice. In stained section low density deep cortex was observed in nude mice specifically. 5. The size of lymph follicle in C_57BL/6 mice is 0.405mm and in nude mice 0.795mm

사회인지론에 근거한 낮병원 정신질환 입원환자 대상비만 예방 및 관리를 위한 영양교육 효과평가

한민지,이지연,이해연,한은경,최경순,김희선 순천향대학교 기초과학연구소 2021 순천향자연과학연구 논문집 Vol.27 No.1.2

Mental illness such as schizophrenia, bipolar disorder and depression have shown high prevalence of obesity. According to the previous studies, nutrition education has therapeutic effects on patients, however mentally ill patients rarely have opportunities of long term nutrition education. In this study, nutrition education based on the social cognitive theory was conducted. Patients with mental illness received education program once a month during 18 months in a day hospital. Fifteen patients were included and divided into two groups according to the attendance rate. Results showed that the group attended the education more than 10 times showed weight loss, while the group less than 10 times showed weight gain. Five long-term hospitalized patients gained weight during one year prior to the nutrition education, but showed weight loss during one year with the nutrition education. Regardless of the number of attendance, the group of BMI≥30kg/m2 showed weight loss. Although this study has several limitations and did not obtain a statistically significant results, it confirmed the necessity of providing clinical nutrition services including nutrition education for mentally ill patients.

복수과 진료 환자의 중복 처방에 대한 분석 및 평가

이지은,장혜경,오지영,유윤경,김현지,임숙인,연숙희,강진숙,최귀령 한국병원약사회 2003 병원약사회지 Vol.20 No.1

In an aging society, there is an increasing possibility of the duplication of the drugs given to patients because they take many kinds of drugs. Among the prescriptions given to the patients who was treated at multiple ambulatory clinics in St. Mary's hospital for one month of September, 2002, in which drugs that has identical or similar effects are prescribed, we analysed and evaluated them by patients' characteristics, kinds of medication, severity of side effects on a case by case basis. More, we assessed the potential additional costs. As a result of this study, the duplication rate turned out to be 6.69% and it was shown that the proportion of the elderly patients over 60 was high. The gastro-intestinal medications took up a large part and most of the cases showed that the danger caused by double taking of medicine was slight, but there were some examples in which the serious side effects were predicted. Expected additional costs were the average 11.349 won and it ranges from the minimum of 56 won to the maximum of 135,720 won. In conclusion, the management of drug histories of the patients who need the plural treatments is very important and the necessity of the individual and professional guidance of taking medicines for the elderly patients is emerged, too.

거대 신생아의 혈당치와 철함유량의 관계에 관한 연구

정지희,김창휘 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.2

Infants of large for gestational age have a higher incidence of birth injury. neonatal hypoxia and congenital anomalies. Also they likely to have a hypoglycemia due to hyperinsulinemia, and changes in serum ferritin and transferrin levels. We investigated the relationship between hemoglobin, hematocrit, serum iron, ferritin, transferrin and insulin levels according to blood glucose level in 61 large(11 cases of hypoglycemic and 50 cases of normoglycemic) and 21 appropriate for ges-ational age infants. The results are as follows: 1. The incidence of large for gestational age(LGA) infant was 12%(70 among 584) and the incidence of LGA from gestational diabetic mother was 16.4%(10 among 61). 2. The mean birth weights were 4.1 kg in hypoglycemic LGA, 4.2 kg in normoglyce-mic LGa and 3.4 Kg in normoglycemic appropriate for gestational age(AGA) infants. 3. The mean hemoglobin levels were 16.1±1.2 g/dl in hypoglycemic LGA, 15.2±1.3 g/dl in normoglycemic LAG and 15.1±1.7 g/dl in normoglycemic AGA infants. The mean hematocrit levels were 53.3±5.2% in hypoglycemic LGA, 49.4±4.6% in normoglycemic LGA and 49.5±6.3% in normoglycemic AGA. 4. Serum iron and ferritin levels were significantly lower in hypoglycemic LGA(60.4±34.3 g/dl , 73.1±22.8 ng/ml, respectively) than normoglycemci LGA(99.8±59.1 ug/dl, 158.1±84.0 ng/ml, respectively) and AGA(108.0±51.9㎍/dl, 144.3±99.6 ng/ml, respe-ctively) infants(p<0.05). The serum transferin levels were significantly increased in LGA than AGA(203.5±20.8 mg/dl) infants(p<0.05), but there was no significant differences between hypoglycemic(262.4±28.2 mg/dl and normoglycemic(241.0±36.1 mg/dl) LGA infants. 5. Serum insulin levels were significantly higher in LGA(6.8±2.8 μU/ml for hypoglycemic and 5.8 ± 4.3 μU/ml for normoglycemic) than AGA(0.1μU/ml) infants(p<0.05).

그림좌절 검사와 다면적 인성검사에서 나타난 살인 정신분열증 환자와 정상대조군의 공격반응의 차이

조지희,이근후 大韓神經精神醫學會 1992 신경정신의학 Vol.31 No.3

The purpose of this study was to investigate the difference between normal control group and schizophrenic patients who committed homicidal behavior in response to frustration using P.F.T.(Picture-Frustrations-test) and MMPI. The study subjects were 77 homicidal schizophrenics who were admitted to the Forensic Psychiatric Institution from October, 1989 to February, 1990 and 83 normal control group who had no crime history and psychiatric problem. The following results were obtained : 1) As to the direction in P.F.T., homicidal schizophrenics responded rather in intropunitive or impunitive direction than in extrapunitive direction compared with normal control group. 2) As to the reaction type in P.F.T., homicidal schizophrenics showed more need-persistence(N-P) type and less obstacle-dominance(O-D) type than normal control group. 3) Regarding the superego factors in P.F.T., homicidal schizophrenics showed significantly less socore in E, I, E+E, E-E and M+I response than normal control group. 4) Homicidal schizophrenics exhibited significantly less G.C.R. score than normal control group, which is correlated with sociality and appropriateness for age in response to frustration. 5) In the validity scale of L, F, K and in the clinical scale of D, Pd, Pa, Pt, Sc on MMPI, homicidal schizophrenics remarked significantly high T score than normal control group. Especially in L scale and Pa scale, the difference of two groups was most prominent.