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Novel Repair Technique for Articular Cartilage Defect using a Fibrin and Hyaluronic acid Mixture
( Jae Deog Jang ),( Young Seok Moon ),( Yong Sik Kim ),( Nam Yong Choi ),( Hyun Su Mok1 ),( Young Ju Kim1 ),( Asode Ananthram Shetty ),( Seok Jung Kim ) 한국조직공학·재생의학회 2013 조직공학과 재생의학 Vol.10 No.1
We evaluated the cartilage repair potential of a hyaluronic acid and fibrin mixture when transplanted into cartilage defects. Circular, articular, cartilage defects 4-mm in diameter were made in the trochlear region in 21 New Zealand white rabbits divided into three groups. The seven rabbits in the control group underwent microfracture (M group), the seven rabbits in the experimental group underwent microfracture with subsequent injection of hyaluronic acid mixed with fibrin (MH group), and seven rabbits in the other experimental group underwent microfracture followed by injection of bone marrow concentrate and hyaluronic acid mixed with fibrin (MBH group). At week 12 following surgery, the cartilage was observed and histologically compared in the three groups. The surface of the newly generated cartilage was very smooth and even, and we noticed that the entire area was completely regenerated in both experimental groups. The control group showed incomplete and irregular cartilage formation in the defect. In histologic scoring, comparison of the MBH group (M= 2.333) and the M group (M= 9.000) differed significantly (P= 0.046). Therefore, injection of a mixture of bone marrow concentrate, hyaluronic acid and fibrin to treat articular cartilage defects of the knee appears to be an effective method of cartilage regeneration.
Gray 사상을 이용한 이진 낮은 상관구역 수열군의 생성법
장지웅(Ji-Woong Jang),김영식(Young-Sik Kim),임대운(Dae-Woon Lim) 한국통신학회 2009 韓國通信學會論文誌 Vol.34 No.2C
본 논문에서는 이진 낮은 상관 구역 수열군의 새로운 생성법을 제안한다. 새로운 수열군은 Kim과 Jang, No, Chung이 제안한 4진 낮은 상관 구역 수열군에 Gray 사상을 적용하여 생성한다. 새로 생성된 이진 수열군의 주기는 생성에 사용한 4진 수열군의 주기의 2배이며, 낮은 상관구역 내 상관 값의 최대 크기 및 수열군의 크기는 생성에 사용한 수열군의 그것의 2배가 된다. 그러나 낮은 상관 구역의 크기는 그대로 유지된다. 생성에 사용한 4진 낮은 상관 구역 수열군의 최적인 경우 새로 생성된 이진 수열군은 높은 확률로 최적의 수열군이 된다. In this paper, we propose a new construction method of binary low correlation zone (LCZ) sequence set. New construction method applies Gray mapping to conventional quaternary LCZ sequence set that has specific property. The period of new binary sequence set is twice as that of used sequence set in construction, and maximum magnitude of correlation value within the LCZ and cardinality of new set is also twice as those of used quaternary sequence set. But the LCZ size is the same with that of used sequence set. If the used quaternary sequence set is optimal, the constructed binary sequence set is optimal with high probability.
윤장효,염경호,김우식,김원규 연세대학교 대학원 1986 延世論叢 Vol.22 No.1
The dynamic characteristics and mass transfer effects in Para-type plate pulsed column was investigated. The axial dispersion coefficient of continuous phase was constant in the range above that continuous phase flow rate was 200ml/min, and was more influnced by amplitude than by frequency. The hold-up of continuous phase was more influnced by amplitude and saunter mean diameter was more influnced by frequency. As the experimental results of acetone extraction, the column efficiency was slightly decreased with the pulse velocity increased, but was stabilized in the range of 80~90%. The acetone concentration profiles with the change of column height at steady state more approached to the backflow model than the diffusion model.
김윤성,구본길,차종식,박장규,이영 충남대학교 의과대학 지역사회의학연구소 1984 충남의대잡지 Vol.11 No.1
Mondor's disease has been regarded as an obliterative phlebitis usually affecting superficial vein of the chest wall. It is characteristic that the cord-like thrombosed vein which is red and tender at first changes into painless fibrous band. In the past, it was confused with lymphatic spread of carcinoma but it was confirmed that it was benign and related with the systemic diseases or cancer. The authors observed a 57-year-old female with Mondor's disease. 15 days ago, she notified the cord-like lesion on the right chest well, from right axillar fold to right iliac crest. 1. month later, the skin lesion much improved without special treatment.
초소형 구조물의 부착 방지를 위한 새로운 자기 집합 물질에 대한 연구
김봉환,오창훈,전국진,정택동,변장웅,이윤식 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1
In order to achieve stiction-free polysilicon surfaces, we have suggested a new chemical grafting precursor and confirmed their excellent characteristics. When dichlorodimethylsilane(DDS, C_(2)H_(6)SiCl_(2)), a dialkyldichlorosilane widely used in silicon machining, have been used as a precursor, experimental results were clearly comparable to those of monoalkyltrichlorosilanes octadecyltrichlorosilane (OTS, C_(18)H_(37)SiCl_(3)) or 1H,1H,2H,2H-perfluorodecyltrichloro-silane (FDTS, C_(10)H_(4)F_(17)SiCl_(3)) in terms of stiction reduction. The polysilicon cantilevers were fabricated in the carefully controlled conditions and laser interferometer indicated that their residual stress gradient was 2 MPa/μm upward from the substrate. The SEM images of polysilicon cantilever beams with DDS coating are upward and no stiction is observed up to 2 mm in length.
김용식,최병호,원장섭 大韓神經精神醫學會 1984 신경정신의학 Vol.23 No.4
The present study purported to explore the relationships between alcoholism and depression in 26 chronic alcoholics who were admitted to National Seoul Mental Hospital. Each of these patients was assessed by Minnesota Multiphasic Personality Inventory, Self-Rating Depression Scale at least 2 weeks after admission, and by dexamethasone suppression test at least 3 weeks after admission according to the medical exclusion criteria(except abnormal hepatic enzyme). The results are summarized as follows: The prevalences of depression in chronic alcoholics are 15% on clinical impression, 23% on self rating depression scale, 53% on Hamilton depression rating scale, 0% on Depression scale of MMPI, 16.7% on Mania scale of MMPI, and 61.5% totally. No significant difference between the normal and the abnormal hepatic enzyme groups was found in 2 serum cortisol levels suppressed by dexamethasone. The two of 26 patients(7.8%) were found to be nonsuppressor by the dexamethasone suppression test. These two patients were converted to suppressor 4 weeks after elavil medication.