Bacillus sp. FF-7에 의한 항산화물질 생산조건과 항산화 활성

차재영,김효정,전방실,박진철,옥민,조영수 한국응용생명화학회 2003 Applied Biological Chemistry (Appl Biol Chem) Vol.46 No.3

발효식품 시료로부터 분리된 세균을 DPPH(α,α¹-diphenyl-β-picrylhydrazyl) 전자공여능으로 항산화 활성을 측정하여 가장 활성이 강한 균주를 선별하여 형태학적, 생화학적, 생리학적 특성 및 16S rRNA 염기서열을 조사한 결과 Bacillus sp.으로 판명되어 FF-7로 명명하였다. DPPH 전자공여능법에 의한 Bacillus sp. FF-7이 생산하는 항산화물질의 최적 생산 배지조건은 탄소원 2% galactose와 질소원 1% tryptone 첨가였다. Bacillus sp. FF-7에 의해 생성된 항산화 물질의 활성을 DPPH 전자공여능, 흰쥐 각 조직 microsomal 실험계 및 linoleic acid 과 산화지질 실험계에서 malondialdehyde를 thiobarbituric acid(TBA)방법으로 측정하였다. 흰쥐 각 조직 microsomal 실험계에서 지질과산화에 대한 항산화 효과는 뇌(97.50%)>심장(79.95%)>신장(77.84%)>비장(77.47%)>고환(69.96%)>간장(62.45%) 순이였다. Linoleic acid의 과산화지질률 TBA법으로 측정한 결과 반응 4일째까지 억제 효과가 강하게 나타났으며, 동시에 대조구로 사용한 0.05% BHT 첨가구에서도 실험종료시까지 항산화 활성이 강하게 나타났다. The antioxidative activity of antioxidative substances produced from several bacterial strains isolated from fermented foods were tested by DPPH (α,α'-diphenyl-β-picrylhydrazyl) free radical scavenging activity. One of the strains showing the highest antioxidative activity was identified as Bacillus sp. based on the morphological, biochemical, physiological characteristics, and 165 rRNA sequence, and named FF-7. The molt optimal medium condition for the production of antioxidative substance from Bacillus sp. FF-7 was 2% galactose as carbon source and 1% tryptone as nitrogen source. The antioxidative substance produced from FF-7 in these cultural medium was also tested by in vitro experimental models, the peroxidation of linoleic acid and the peroxidation of rat tissues microsomes by using thiobarbituric acid (TBA) for assay of free rnalondialdehyde production. The antioxidative avtivity against lipid peroxidation of rat tissues microsomes was shown in the following order; brain 97.50% > heart 79.95% > kidney 77.84% > spleen 77.47% > testis 69.96% > liver 62.45%. The antioxidative substance produced from FF-7 on linoleic acid peroxidation by TBA method was effectively inhibited during four days, and 0.05% BHT(butylated hydroxytoluene) used comparative control was also effectively inhibited. Results showed that the highest antioxidative activity by DPPH method of antioxidative substance produced from Bacillus sp. FF-7 was obtained by supplementing 2% galactose as carbon source and 1% tryptone as nitrogen source in cultured medium, this substance effectively inhibited the formation of TBARS in brain microsome in vitro system and in linoleic acid peroxidation.

CXTFIT기법을 이용한 오염토양의 중금속 이동특성에 관한 연구

오광중,김효진,박창웅,오방일 부산대학교 환경문제연구소 2002 環境硏究報 Vol.20 No.-

The sorption and transport characteristics of Cd and Pb is founded by changing of soil concentration and velocity of injected Cd and Pb solution. The results of batch-type experiment indicated that sorption capacity of Pb was stronger than sorption capacity of Cd. Batch-type experiment indicated that the results of Cd and Pb adsorption experiment fitted in the Freundlich isotherm equation well and were highly nonlinear. Results from column experiment showed the retention of the transport of heavy metals at low concentration, low velocity and high pH in soil of different characteristics. The BTCs of the heavy metals were analysed by using a two-site model, and transport parameters were derived by using the CXTFIT curve-fitting program. The model results indicated that the partitoning coefficient(β), forward rate coefficient(Ks) and backward rate coefficient(kd) were in proportion to the concentration, velocity and pH.

미세혈관 협심증 환자의 임상상 및 지표에 관한 연구

박상호,온영근,김현정,이태훈,길효욱,김현건,박수진,송해정,한대희,방덕원,신원용,이내희,김성구,권영주 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

Background : Microvascular angina or syndrom X is heterogenous and encompasses different pathogenetic entities. Several studies suggest that microvascular angina have good prognosis and occurs predominantly in postmenopausal women. Lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and fibrinogen are the independent risk factor of acute coronary syndrome and are the chief underlying cause of atherosclerosis. We investigated clinical characteristics and markers in patients with microvascular angina. Methods : We studies 23 patients diagnosed with microvascular angina and 16 control group with negative treadmill exercise test and no significant coronary angiogram. We investigated clinical characteristics in patients group and evaluated symptom during a follow-up period of 4.2± 2.5 month. Exercise time in treadmill exercise test was compared between patients and control group. We assessed the level of markers, such as lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, CRP and ESR in two groups. Results : There is no difference in age between two groups. Patients group had a tendency to increase in female, hypertension, DM, and smoking history, but there was no statistical significance difference. Exercise duration time was significantly decreased in patients with microvascular angina (p<0,05). Serum lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholestrol, Triglyceride, ESR, Fibrinogen and Homocystein value were no significant difference between microvascular angina and control group. Only CRP was significantly high in patients with microvascular angina (p<0.05). Conclusion : There was no statistical significance difference in age, sex, hypertension, DM and smoking history between two groups but patients group had a tendency to increase the prevalence in hypertension, DM and smoking history, female. Also, Symptom improvement and disappearance in follow-up was presented in 11 patients of 19(57.9%). Exercise tolerance was worse in patients group than control group. CRP value was significantly higher in patients group than control group. There was no statistical significance difference in lipoprotein (a), total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, homocystein, ESR and Fibrinogen between two groups.

Hepatoprotective effects of allyl isothiocyanate in CCl4-induced chronic hepatic damage in rats

Hyo-jin Bang,Yun-a Choi,Mee-jung Ahn,Jeong-tae Kim,Gi Ok Kim,Tae-kyun Shin 대한수의학회 2016 대한수의학회 학술대회발표집 Vol.2016 No.-

Hepatoprotective effects of Allyl isothiocyanate in CCl4-induced hepatic damage in rats

Hyo Jin Bang,Mee Jung Ahn,Ji Hwan Moon,Giok KIim,Tae Kyun Shin 한국실험동물학회 2015 한국실험동물학회 학술발표대회 논문집 Vol.2015 No.8

Regeneration inverter for DC electric traction system with the capability of reduction of harmonic

Hyo-Jin Bang,Chang-Youl Choi,Su-Jin Jang,Chang-Han Bae,Kyu-Bok Ahn,Chung-Yuen Won 전력전자학회 2004 ICPE(ISPE)논문집 Vol.- No.-

This paper proposes a dc power system, which can generate the excessive dc power from dc bus line to ac source in substations for traction system. The proposed regeneration inverter system for dc traction can be used as both an inverter and an active power filter (APF). As a regeneration inverter mode, it can recycle regenerative energy caused by decelerating tractions and as an active power filter mode, it can compensate for harmonic distortion produced by the rectifier substation. From the viewpoint of both power capacity and switching losses, the system is designed on the basis of three phase PWM inverters output transformers and an LCL filter.

Group

Bang, Hyo Jin 한국콘텐츠학회 2019 ICCC International Digital Design Invitation Exhib Vol.2019 No.8

직류전철용 에너지 회생장치 성능개선

방효진(Hyo-Jin Bang),김용기(Yong-Ki Kim),장수진(Su-Jin Jang),송상훈(Sang-Hun Song),안규복(Yu-Bok Ahn),원충연(Chung-Yuen Won) 한국조명·전기설비학회 2004 한국조명·전기설비학회 학술대회논문집 Vol.2004 No.5월

Recently, when electric traction system used DC 1500[Vdc] runs on decline of rail road track and slows down, dc voltage goes beyond regular voltage. In this case extra power is forcibly wasted by resister because rectifier of substation and electric train including power convertor and so on are out of order. Therefore this paper proposes that the extra power is regenerated through regeneration inverter to AC utility in result this system obstruct to go beyond regular voltage and improve the efficiency. In addition, electric traction system products harmonic current and voltage distortion and reactive power because power converter is used so regeneration inverter normally runs such as active power filter(APF) for improving power quality.

내향성 발톱의 교정을 평가하기 위한 발톱 C커브 각도 계측 방법의 제안

방효진 ( Hyo Jin Bang ),이성석 ( Sung Suk Rhee ) 한국미용학회 2011 한국미용학회지 Vol.17 No.4

In this paper, we proposed a new method to measure the C-curve angle of a toenail to evaluate an ingrowing toenail, and analyzed the measured angle of C-curve of toenail to find the related variables, such as, self-judged angle, presence of an ingrowing toenail, walking style, type of shoes, height of heel, the experience of foot care, education and occupation. Basically, in the study of ingrowing toenail, it is important for the C-curve angle of toenail to be a tool of measuring the degree of refraction of toenail, and of evaluating an ingrowing toenail. The survey was performed with questionnaires and the picture of the toenail of respondents were taken. The data from 197 respondents who are female students or female customers of the nailcare shop were analyzed by frequencies, t-test, and F-test (ANOVA). The results of this study were as follows. First, the measured angle of C-curve is very important to study the evaluation of an ingrowing toenail. Second, it is more fit to study the ingrowing toenail than the self-judged angle. Third, it is differed by the presence of an ingrowing toenail. Four, it is differed among the position of the center of mass during walking. Five, it is narrowed in the case of high hill typed footgear. Six, it is narrowed for the group not taken footcare.

유리 기판에서 RF 마그네트론 스퍼터링법으로 증착한 비정질 투명전극 스트론튬 루세네이트 박막 두께에 따른 광학 및 전기적 특성

방효진(Hyo Jin Bang),김현민(Hyun Min Kim),이종훈(Jong Hoon Lee),안지훈(Ji-Hoon Ahn),김홍승(Hong Seung Kim) 한국물리학회 2022 새물리 Vol.72 No.10

스트론튬 루세네이트 (SrRuO₃)의 전극은 페로브스케이트 구조 유전체의 유전 특성을 향상시킬 수 있어 DRAM(Dynamic Random-Access Memory) 에 가장 적합한 전극 재료로 사용되고 있다. 이러한 장점들을 가지고 있는 스트론튬 루세네이트 (SrRuO₃) 박막이 투명 전극(Transparent Conductive Oxide; TCO) 으로의 사용 가능성을 확인해 보기 위해 연구하였다. 본 연구에서, 스트론튬 루세네이트(SrRuO₃) 박막을 유리 기판 위에 RF 마그네트론 스퍼터링 법으로 상온에서 증착 하였다. 박막의 두께에 따른 광학적 특성과 전기적 특성을 관찰하기 위하여 증착 시간을 5분과 50분으로 설정하여 실험을 진행하였다. 증착 시간이 증가할수록 박막 두께가 5nm에서 68nm로 증가하였고 광 투과율이 80%에서 40%로 감소하였다. 전기적 특성인 비저항은 박막 두께가 증가 하면서 1.99 mΩ·cm 에서 26.3 mΩ·cm 로 증가하였다. 결과적으로, 스트론튬 루세네이트(SrRuO₃) 박막을 유리 기판 위에 5분 증착 하였을 때, 약 80%이상의 투과율과 4.57eV의 밴드 갭, 그리고 1.99 mΩ·cm의 비저항을 보여주었다. The SrRuO₃ electrode can improve the dielectric properties of the perovskite structure. Thus, it is the most suitable electrode material for Dynamic Random-Access Memory (DRAM). This study was conducted to investigate the possibility of the SrRuO₃ thin film as a transparent conductive oxide (TCO). In this study, an SrRuO₃ thin film was deposited on the glass substrates by the RF magnetron sputtering method at room temperature. To observe the difference in optical and electrical properties as per the thin film thickness, the deposition times were set to 5 and 50 min. As the deposition time increased, the film thickness increased from 5 to 68 nm, the optical transmittance decreased from 80% to 40%, and the resistivity (an electrical property) increased from 1.99 to 26.3 mΩ·cm. Consequently, when the SrRuO₃ thin films were deposited on the glass substrates for 5 min, a transmittance of about 80% or more, a band gap of 4.57 eV, and a resistivity of 1.99 mΩ·cm were observed, thus verifying that an SrRuO₃ electrode can improve the dielectric properties of perovskite.