측모두부방사선사진과 측면얼굴사진 중첩 시 적합도에 관한 연구

박지영,이기헌,황현식,이종석 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.3

The purpose of this study was to compare the geometric displacement between the lateral cephalometric radiograph and photograph. For the present study, 52 subjects with Angle Class I occlusion and no severe skeletal discrepancy were selected. The Head Posture Aligner and the standardized camera set up were adopted to obtain photographs and radiographs in a standardized manner. Six metal markers were placed on the subject's right side face representing Glabella (G), Zygoma (Zy), Philtrum (Ph), Soft tissue Gonion (Go'), Soft tissue Pogonion (Pog'), Soft tissue Menton (Me') before taking the lateral cephalometric radiograph and photograph. The 14 linear, 28 angular, and 5 area differences were measured after superimposition of the radiograph and photograph using nose and upper lip as a reference on the Image Analyzer. The paired t-test and the percentage of differences were used to compare the geometric displacement of metal markers between the lateral cephalometric radiograph and photograph. Through the statistical analysis, the following results were obtained. 1. When the linear measurements were compared between the lateral photograph and radiograph, the measurements related to Zy and Go' except Zy-Me' and Go'-Ph showed significant differences on both images. 2. On the angular comparison, the overall measurements except Me'-Ph-Pog', Ph-Pog'-Me', Ph-Me'-Pog', G-Me'-Ph, Me'-G-Ph. Ph-Go'-Pog', Go'-Zy-Me' and G-Go'-Me' showed significant differences on both images and especially the measurements related to Zy showed greater difference. 3. In area measurements, the overall measurements except G-Zy-Go' showed enlargement of the radiograph. 4. On the superimposition of the radiograph and photograph, the measurements related to the profile tended to be well matched. However, Zy on the lateral radiograph tended to be displaced downward and backward more than Zy on the photograph. Furthermore Go' on the lateral radiograph tended to be displaced upward and backward more than Go' on the photograph. The results suggested that the precise superimposition between the lateral cephalometric radiograph and photograph was not feasible due to differences in enlargement.

고정식 교정 환자에서 전동치솔 효과에 관한 연구

박창헌,이기헌,황현식,홍석진 전남대학교 치의학연구소 2002 구강과학 Vol.14 No.4

Patients with fixed orthodontic appliances frequently have increased levels of plaque accumulation leading to the possibility of gingivitis or enamel decalcification. Although many methods may be helpful in reducing dental plaque formation, optimal mechanical removal of plaque is tile most important factor during orthodontic treatment. The porpose of this study was to evaluate the efficacy of'an electric toothbrush, with a specially designed orthodontic brush head. compared with a manual toothbrush in controlling plaque and gingivitis for patients with fixed orthodontic appliances. Oral hygiene status was measured in thirty four patients, using a plaquc index, a gingival index and a bleeding index. before and four weeks after attachment of fixed orthodontic appliances. Patients were randomly divided into two groups, the electric and the manual toothbrush groups. Oral hygiene instruction was given according to the type of toothbrush used. The Braun Oral-B D9511 with Braun Oral-B Ortho OD 15-1 brush head was used as the electric toothbrush while the Butler G.U. M 124 was given as the manual toothbrush. After 4 weeks and 8 weeks, oral hygiene status was measured again. Through the comparison berween the electric and the manual toothbrush grpups. following results were obtained. 1. All oral hygiene indices showed increasing tendency after 4weeks of fixed orthodontic appliances. 2. All indices presented decreasing tendency four and eight weeks after oral hygiene instruction. 3. In case of gingival index and bleeding index. decreasing tendency did not show a statistically significant difference between the electric and the manual toothbrush groups. 4. The decreasing tendency of plaque index presented statistically significant difference between the two groups. showing that the electric toothbrush was more effective in terms of oral hygiene. These findings suggest that an electric toothbrush is useful to the orthodontic patients with fixed appliances.

고정식 교정 환자에서 전동치솔 효과에 관한 연구

박창헌,황현식,이기헌,홍석진 대한치과교정학회 2004 대한치과교정학회지 Vol.34 No.4

고정식 교정장치를 부착한 경우 장치주위의 치태 축적 가능성이 증가되고 이로 인해 치은염, 법랑질 탈회 등의 부작용이 초래 될 수 있는 바 치태 제거를 위한 효과적인 치솔질이 필요하다. 본 연구는 교정환자에서 일반적으로 사용되고 있는 치솔에 비하여 전동치솔이 구강위생에 도움이 되는지 알아보기 위하여 시행되었다. 고정식 장치에 의한 교정치료 예정인 환자 34명을 본 연구의 대상으로 하여 고정식 교정장치 부착 전에 치태지수, 치은염지수, 치은출혈지수를 측정하였다. 장치 부착 4주 후에 각 지수를 측정한 다음, 연구대상을 치솔의 종류에 따라 전동치솔군과 수동치솔군으로 임의 구분하여 수동치솔 또는 전동치솔을 사용하도록 구강위생교육을 각각 시행하였다. 이때 전동치솔의 경우 본체는 Braun Oral-B D9511을 브러쉬 헤드는 Braun Oral-B Ortho OD 15-1을 사용하게 하였으며, 수동치솔의 경우는 Butler G.U.M 124를 사용하게 하였다. 구강위생교육 4주 및 8주 후에 각 지수를 측정한 다음 시간 경과에 따른 전동치솔군과 수동치솔군의 구강위생 상태를 비교 분석하여 다음과 같은 결과를 얻었다. 1. 고정식 교정장치 부착 4주 후 치태지수, 치은염지수, 치은출혈지수 모두 증가 양상을 나타내었다. 2. 구강위생교육 후 치태지수, 치은염지수, 치은출혈지수 모두 감소 양상을 나타내었다. 3. 치은염지수, 치은출혈지수의 경우 감소양상이 수동치솔과 전동치솔군 간의 유의한 차이를 보이지 않았다. 4. 치태지수의 경우 수동치솔에 비해 전동치솔군에서 감소효과가 유의하게 크게 나타났다. 이상의 연구 결과는 고정식 교정장치로 치료받는 환자에서 전동치솔이 구강위생에 도움이 됨을 시사하였다. Patients with fixed orthodontic appliances frequently have increased levels of plaque accumulation leading to the possibility of gingivitis or enamel decalcification. Although many methods may be helpful in reducing dental plaque formation, the optimal mechanical removal of plaque is the most important factor during orthodontic treatment. The purpose of this study was to evaluate the efficacy of an electric toothbrush (with a specially designed orthodontic brush head) compared to a manual toothbrush in controlling plaque and gingivitis for patients with fixed orthodontic appliances. Oral hygiene status was measured in thirty-four patients using a plaque index, a gingival index and a bleeding index, before and four weeks after the attachment of fixed orthodontic appliances. Patients were randomly divided into two groups: electric and manual toothbrush groups. Oral hygiene instruction was given according to the type of toothbrush used. The Braun Oral-B D9511 with Braun Oral-B Ortho OD 15-1 brush head was used as the electric toothbrush while the Butler G.U.M. 124 was given as the manual toothbrush. After four and eight weeks, oral hygiene status was measured again. Through a comparison between the electric and the manual toothbrush groups, the following results were obtained. 1. All oral hygiene indices showed an increasing tendency after four weeks of fixed orthodontic appliance. 2. All indices presented a decreasing tendency four and eight weeks after oral hygiene instruction. 3. In case of the gingival index and bleeding index, the decreasing tendency did not show a statistically significant difference between the electric and the manual toothbrush groups. 4. The decreasing tendency of plaque index presented a statistically significant difference between the two groups, showing that the electric toothbrush was more effective in terms of oral hygiene. These findings suggest that an electric toothbrush is useful to orthodontic patients with fixed appliances.

Sertraline이 Bleeding Time에 미치는 영향

박현숙,장기용,김은남,강병조 대한생물치료정신의학회 1998 생물치료정신의학 Vol.4 No.2

본 연구는 선택적 세로토닌 재흡수 억제제(SSRIs), 특히 sertraline이 출혈 시간에 미치는 영향을 알아봄으로써 선택적 세로토닌 재흡수 억제제의 안전성과 혈액학적 부작용 측면을 평가하고자 하였다. 선택적 세로토닌 재흡수 억제제의 치료적 적응증에 해당하는 95명의 환자를 무작위 할당으로 sertraline 50mg 투여군, sertraline 200mg, 투여군, nortriptyline100mg 투여군, 위약(thiamine 100mg) 투여군으로 분류하여 정해진 양을 4주간 투여한 후 출혈 시간을 약물 투여 전, 약물 투여 2주 후, 약물 투여 4주 후의 3회에 걸쳐서 측정하였다. 95명의 환자 중 78명이 실험을 마쳤다. Sertraline 50mg 투여군에서 실험 전과 비교하였을 때 시간에 따르는 출혈 시간의 증가가 있었다. 다른 군에서는 실험 전과 실험 2주 후, 4주 후의 출혈 시간을 비교하였을 때 시간에 따르는 출혈 시간의 증가가 없었다. 연구 기간 동안 지혈 이상을 보인 환자는 없었다. 결론적으로 Sertraline 투여 초기에 정상 범위 내에서 출혈 시간의 증가가 있었다. Objective : This study was designed to assess the safety and hematological complications of the selective serotonin reuptake inhibitors(SSRIs) by examining the effect of sertraline on bleeding time. Method : Ninety five patients included in therapeutic indications of SSRIs were divided into sertraline 50mg, sertraline 200mg, nortriptyline 100mg, placebo(thiamine 100mg) groups. Bleeding time was measured at baseline, and repeated 2 and 4 weeks after the initiation of treatment with sertraline, nortriptyline and placebo 78 patients completed the study protocol. Result : Bleeding time was prolonged within normal range after 2 and 4 weeks of treatment in sertraline 50mg administration group. Bleeding time was not prolonged in the other groups. No patient developed clinical signs of abnormal hemostasis during the study period. Conclusion : Bleeding time was prolonged within normal range at initial period of treatment with sertraline.

알루미늄과 헤테로폴리산으로 개질된 메조포러스 실리카 상에서의 AKD 합성

김현국,우창수,최재석,박민태,이병민,이호인 한국공업화학회 2003 응용화학 Vol.7 No.1

AKD(alkyl ketene dimer) used widely as a neutral sizing agent is produced industrially by halogenization of stearic acid followed by dimerization of alkyl ketene. In the present work, to suppress the byproduct of hydrochloric acid and to improve reaction pathway. AKD was prepared through of ketene intermediate by dehydration of stearic acid in gas phase using reaction with silanol on silica as active sites of the catalyst SBA-15 showed the highest activity due to the large and open tubular pores. It was found that main products were dimer and trimer. Our goal of the present work was to increase of the selectivity for the dimer.

다운증아 어머니의 기대성향이 비계화 교수와 문제해결학습에 미치는 효과

여광응,윤숙경,박현옥 한국특수교육문제연구소 2003 특수교육저널 : 이론과 실천 Vol.4 No.1

이 연구는 어머니-다운증아의 상호작용을 통한 문제해결과정에서 어머니의 기대성향이 어머니 교수중재의 양과 수준에 미치는 영향과 다운증아의 적목피라미드 문제해결과제에 미치는 효과를 밝히는데 두고 다운증아 어머니의 기대성향에 따른 어머니의 비계화 교수와 아동의 문제해결학습간의 관계를 탐색하고자 하는 것으로,만 6세인 다운증아 남아 3 명과 여아 3명인 전체 6 명 그리고 그 어머니들을 대상으로 하였다. 어머니-아동의 문제해결상호작용과정을 비디오로 촬영하여,어머니의 교수중재는 중재 수준,중재 양,유관 및 비유관 여부를 중심으로 그리고 아동의 문제해결은 성패를 중삼으로 양적 · 질적 분석을 병행 하였다. 연구결과 어머니의 기대성향이 긍정적일수록 아동의 문제해결 성패에 기반하여 중재 양과 중재 수준을 조절하는 유관 중재를 많이 사용하고 문제해결학습에서 부정적 기대성향의 다운증 자녀보다 더 긍정적 학습결과를 보인다. 또한 어머니의 비계화 교수 변인과 자녀의 문제해갤학습 변인사이에는 상호 관련작 양방향성 효과가 있다. The purpose of this study was to examine the relationships between maternal expectancy and maternal use of scaffolded instruction and problem-solving skills of children with Down syndrome. For this purpose, three boys and three girls with Down syndrome whose age were six years old and their mothers participated in this study. The mother-child interaction regarding problem-solving tasks was videotaped and analyzed. The qualitative and quantitative analyses were conducted to find out the condition and quantity of scaffolded instruction used by mothers, and degree of their contingency of the tasks. In addition, it was analyzed whether these children resolved given problems successfully or not. As a result, it was found that the mothers who had more positive expectancy relied more on contingent intervention that regulated the quality and quantity of instructions based on the success or failure of their child' s problem solving tasks, and that their children produced better learning outcome than the children of the mothers who had more negative expectancy. In addition, two-way interrelationships between the scaffolded instruction variable of the mothers and their children ’ s problem-solving learning variable were found.

오원천의 식물플랑크톤 군집에 대한 연구

주현수,김진,박종천,정원석,송현철,이용탁,이우범 國立麗水大學校 環境問題硏究所 2004 環境硏究論文集 Vol.6 No.-

We carried out a study on phytoplankton community at Owon stream, Jeollabukdo, Korea. The author have examined 83 taxa of the phytoplankton from researched area. These were composed of 5 classes, 11 orders, 21 families, 44 genera, 79 species, and 9 varieties. The composition of occurrence species were as follows: green algae are 48.2%, diatoms are 33.7%, blue green algae are 10.8% and etc(7.3%). Dominant species were Chlamydomonas angulosa, Pandorina morum, Coelastrum microporum, Scenedesmus quadricauda, Staurastrum gracile, Melosira varians, Me. italica, Synedra ulna, Sy. acus, Cocconeis placentula, and Cymbella tumida. The standing crops varied from 1,650cells/ℓ to 47,000cells/ℓ. Phytoplankton density of Owon stream were lower about 8.6 times to a 1,531 times than those of other lakes and rivers in Korea. So, to preserve the water quality in Owon stream we have to manage continuously on the nitrogen and phosphorus.

남자 만성 정신분열증 환자에서 Risperidone 투여에 의한 치료반응과 혈장HVA 및 5-HIAA 농도와의 관계

김형섭,조숙행,강대엽,박성덕,김광현 용인정신의학연구소 1997 용인정신의학보 Vol.4 No.2

항암화학요법을 받는 암 환자에 대한 Nucare^R의 영양지지효과

조덕연,김현수,곽상혁,강정현,김철희,배광봉,김종숙,박상준,윤환중,김삼용 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

Purpose : The purpose of this study was to evaluate the effect of nutritional support with enteral liquid supplement in cancer patients receving chemotherapy for possible benefit in nutritional, immunologic and golbal function of patients. Patients and Methods : From October 1995 to February 1997, 30 advanced cancer patients receving chemotherapy were divided two roups. The Nycare group, in addition to normal diet, Nucare^R enteral supplement was given for 1week right after chemotherapy for the duration of 2 chemotherapy cycles. Control group received only normal diet without parenteral fluid supplement for 2 chemotherapy cycles. Results : Median ages were 53 end 56 years for Nucare group and Contrl group respectively. Performance scores was less than 2 by ECOG scale. All patients were stage Ⅲ or Ⅳ. The physical parameters, such as weight, arm muscle circumference(AMC) and triceps skin fold(TSF) were decreased in both groups after 2 cycles of anticancer therapy. but it was less severe in Nucare group(p<0.05). Serum transferrin was maintained in mild deficit state in Nucare group, whereas it aggravated form mild to moderate deficit in Control group(p<0.05). Serum albumin level increased in Nucare group without statistical significance. but it decreased from normal to mild deficit in Control group. Serum total protein did not change significantly in Nucare group. but in Control group, serum total protein was decreased from 7.24±0.9 to 6.52±0.5(P<0.05). Total lymphocyte count did not change significantly in both groups. Conclusion : This study shows that the nutritional support with Nucare^R was effective in the prevention of nutritional deficit status in patients receving a nticancer chemotherapy.

FCL(5-FU, Carboplatin, Leucovorin) 항암 화학요법에서 Gm-CSF의 효과

최지영,김현수,김종숙,박상준,윤환중,조덕연,남상륜,김삼용 忠南大學校 癌共同硏究所 1998 癌共同硏究所 硏究誌 Vol.2 No.1

Background: One of the major side effects of cancer chemotherapy is myelosuppression. Neutropenia and/or thrombocytopenia are dose-limiting factors in chemotherapy. Colony-stimulating factor induces proliferation and functional maturation of hematopoietic progenitor cells. GM-CSF is primarily active on progenitor cells of granulocytic and monocytic lineage. Methods: Fifteen patients with histologically proven malignancy diagnosed at Chungnam National University Hospital from January 1993 to August 1995 were included in this study. We could evaluate the clinical efficacy of GM-CSF in 13 patients undergoing FCL(5-FU, Carboplatin and Leucovorin) chemotherapy; the first cycles involved no GM-CSF while the second cycles involved GM-CSF on day 6 through 15 of chemotherapy. Results: 1) The subjects were fifteen patients in all, there were five patients with head and neck cancer, which was the most common types of maligancy. There were four patients with colon cancer, two patients with stomach cancer, and one patient with breast cancer, gallbladder cancer, cervix cancer and cholangiocarcinoma respectively, two patients, who did not complete two cycles of chemotherapy were excluded. 2) Age distribution was from 38 years to 78 years with a median age of 57. 3) In FCL chemotherapy cycles with GM-CSF, the duration of neutropenia(<500/μL) was 0.5±0.3 day, while FCL chemotherapy cycles without GM-CSF, it was 2.9±0.7 day(P=0.008). 3) There was no significant difference in platelet count between the two chemotherapy cycles(P=0.133). 4) Febrile duration without GM-CSF was 4.9±2.1 day, but with GM-CSF the duration was 1.3±0.7 day, which was significantly different(P=0.003). The duration of antibiotics use with GM-CSF was 1.7±1.2 day and without GM-CSF was 6.8±3.2 day, also significantly different(P=0.002). But hospital stay between the two cycles were not significantly different(P=0.064). Conclusion: GM-CSF was effective in preventing or restoring bone marrow depression after FCL chemotherapy.