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      • 무용수의 심상 자극 동안 두뇌 영역별 뇌파 활성도 변화

        송채훈,정혜선,심준영 한국스포츠리서치 2005 한국 스포츠 리서치 Vol.16 No.2

        This study is to examine electroencephalogram (EEG) activity by regions of brain during imagery stimulation with 33 women who majored in dance and has a 10-year dance career and 33 general women university students. EEG was measured at stability state before imagery stimulation as the first measurement and during imagery stimulation as the second one for five minutes respectively. Relative powers at 8 EEG channels including FP1, FP2, F3, F4, C3, C4, P3 and PI by frequency bands. As a result of analysis, 8 channels of theta waves including FP1, FP2, F3, F4, C3, C4, P3 and P4 showed significant difference between groups. In particular, In the mean value of 8 channels by groups, dancer group showed a larger increase of theta wave than general group during imagery stimulation. Also in relative activity of left and right brain of theta wave. danger group showed a dominant activity at right brain. F4, C4 and P4 compared to general group. These results suggested that in dancers' imagery. EEG kept efficient stability state and their ability to give attention to internal experience was also excellent.

      • 갑상선기능저하증 이환견에 대한 치료 증례

        김혜원,이선희,임수정,박형진,김태신,송은식,송근호 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2009 動物醫科學硏究誌 Vol.16 No.1

        A 10-year-old, male, poodle dog was referred to the Veterinary Medical Teaching Hospital of Chungnam National University because of continuous cough and cardiomegaly. Weight gain, lethargy, unwillingness to exercise and decreased activity was revealed on history. Obesty and alopecia was also observed on physical examination. Hypercholesterolemia and increased ALP was revealed on blood exam. So, evaluation of thyroid gland function was performed and cTSH concentration was increased. tT4 and fT4 concentrations was decreased. Results of a history, physical examination, blood exam, and thyroid gland fuction test support a diagnosis of hypothyroidism. Initial therapy with sodium levothyroxine was indicated. On 32 days after treatment of hypothyroidism, clinical signs was relieved and cTSH concentration was decreased, tT4 and fT4 concenctrations was increased.

      • 감귤류의 Ascorbate 및 Phenolic 획분이 N-nitrosodimethylamine의 생성에 미치는 영향

        송미향,이수정,신정혜,최선영,성낙주 한국식품영양학회 2002 韓國食品營養學會誌 Vol.15 No.2

        감귤류 (자몽, 레몬, 금귤, 밀감 및 오렌지)를 착즙하여 얻은 쥬스를 sep-pak C_18 cartridge를 사용하여 ascorbate 및 phenolic 획분으로 분리한 다음 pH를 달리한 in vitro 반응계에서 아질산염 소거 및 N-nitrosodimenthylamine(NDMA) 생성억제 효과를 분석하였다. 감귤류 쥬스 ascorbate 획분의 아질산염 소거능은 5ml 첨가시 pH 2.5 에서 79.9 ~ 98.6%, pH 4.2에서 48.5 ~ 86.3%였으나, pH6.0에서는 35.2% 이하였다. Phenolic 획분은 ascorbate 획분에 비해 높은 소거능을 보였으며 특히 pH6.0 에서는 ascorbate 획분에 비해 2배 이상의 높은 소거능을 나타내었다. NDMA 생성억제 효과는 phenolic 획분의 첨가시에 월등히 뛰어나 pH 2.5의 반응용액에 금귤, 밀감 및 오렌지쥬스의 phenolic 획분을 첨가했을 때 92.8% 이상이었으나, ascorbate 획분이 첨가된 경우에는 NDMA 생성 억제 효과를 거의 나타내지 못하였다. 따라서 감귤류 쥬스의 NDMA 생성억제와 관련된 주된 인자는 phenol 화합물인 것으로 사료된다. Five citrus juices were separated into a ascorbate and phenolic portion using sep-pak C_18 catridge, respectively, in order to elucidate the nitrite scavenging effect and N-nitrosodimethylamine (NDMA) formation in model system. the nitrite scavenging effect of ascorbate portion from citrus juices, in the different pH, when added with 5ml were 79.9 ~ 98.6% under the condition of pH 2.5, 48.5 ~ 86.3% at pH 4.2 and lower than 35.2% at pH 6.0. The nitrite scavenging effect was excellent phenolic portion rather than ascorbate portion. Particularly, the effect was more 2 times than ascorbate portion under the reaction condition of pH 6.0. When added the phenolic portion in the reaction mixture, NDMA formation was inhibited 92.8% or more in kum quat, mandarin orange and sweet orange juices. But the ascorbate portion was a negative response of the inhibition of NDMA formation. The inhibition on NDMA formation in citrus juice may be due to phenolic compounds were reacted.

      • 무용수들의 스트레스 요인에 관한 고찰

        송채훈,정혜선 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.3

        As modern society becomes highly industrialized, pluralized and specialized, man urges his way to success through ceaseless challenges for Information and competition, During the course, the discrepancies between personal desire and environment lead one to stress, one of the necessary evils in modern society, and excessive stress will cause serious psychological or physical damage, whose degree is diverse among individuals, When the dancers suffer from emotional anxiety or struggle due to stress, though not in the state of physical illness or injury, they would surely fall in exerting every effort, and such failure will give them a crucial harm in their lives as dancers, On the contrary, however, having dancers sustain certain amount of stress through proper degree of reaction or awakening might be an important factor to help the dancers develop their dance techniques and adapt themselves as successful dancers, Therefore, in order to fulfill such alms of study, this paper investigated the courses and causes of stress, and the physical and psychological influence of it on individual dancers. And the ways to cope with the stress and their psychological aspects have been discussed, For the dancers, who express their works through the movements of their bodies, to exert the best performing ability, they have to do their best to sustain their psychological condition in an optimum state. Dance trainers and leaders and dance psychologists as well should find out the causes of diverse stresses, and provide effective programs to cope with them, creating some buffering methods against stresses for the dancers.

      • KCI등재
      • 식도암과 위암이 동시에 발생한 원발성 중복암 1예

        윤혜원,심기남,나선경,송도경,정정화,정가영 이화여자대학교 의과학연구소 2012 EMJ (Ewha medical journal) Vol.35 No.2

        Double primary cancers are two independently developed cancers in an individual. There have been some reports on double primary cancer since Billroth reported it for the first time in 1879. Double primary cancer of the stomach and esophagus has been revealed a very low incidence worldwide. The incidence of an esophageal cancer with another primary cancer is reported to be 9.5∼27%, but double primary cancers in the esophagus and stomach have been rarely reported to our knowledge. In this study, we present here a case of double primary esophageal and stomach cancer in a 66-year-old man because of progressive dysphagia.

      • KCI등재

        인체혈장 중 에탐부톨의 HPLC 분석법의 검증 및 단일용량 투여에 의한 약물동태 연구

        곽혜선,박경호,최준식,송진아,성민경,장정옥,이화정 한국약제학회 2005 Journal of Pharmaceutical Investigation Vol.35 No.2

        An HPLC method was employed for the determination of ethambutol in human plasma. After addition of internal standard (IS, octylamine, 2 μg/mL) and alkalinization of the plasma with 5 M sodium hydroxide, the drug and IS were extracted into the mixture of chloroform and diethyl ether (40:60, v/v). Following a 15-min vortex-mixing and a 10-min centrifugation, the organic phase was spiked with 100 pL of phenylethylisocyanate (2000 μg/mL) for chemical derivatization, mixed for 5 min and evaporated to dryness under a stream of nitrogen. The residue was reconstituted with 100 μL of mobile phase and 20 pL was injected into Cl8 column with a mobile phase consisting of methanol:water (70:30, v/v). The samples were detected utilizing an ultraviolet detector at 200 nm. The method was specific and validated with a limit of 0.15 μg/mL. Infra- and inter-day precision and accuracy were acceptable for all quality control samples including the lower limit of quantification. The applicability of this method was demonstrated by analysis of human plasma after oral administration of a single 1200-mg dose to 20 healthy subjects. From the plasma ethambutol concentration vs. time curves, the mean AUC was 9.61 ± 1.64 μg hr/mL. and Cmax of 2.68 μg/mL reached 2.73 hr after administration. The mean biological half-life of ethambutol was 3.46 ± 1.21 hr. Based on the results, this simple and validated assay could readily be used in any pharmacokinetic studies using humans.

      • KCI등재

        한・일 의뢰표현의 일고찰 - 수수동사에서 파생된 의뢰형을 중심으로

        송혜선(Song, Hye?sun) 가천대학교 아시아문화연구소 2020 아시아문화연구 Vol.54 No.-

        수수동사구문에는 이익주체와 이익대상이 구문에 존재하고 있고 구문에 따라서는 이익물이 더해지거나 하는 구조를 이루고 있다. 그와 같은 수수동사구문의 문의 내부구조에 이익주체와 이익대상이 존재하지 않고 화자가 청자에게 영향을 미치는 구조로 바뀌게 되면, 「의뢰」구문으로 이행가게된다. 본고에서는 수수동사에서 파생된 의뢰표현의 구조를 화자(話者)와 청자(聴者)사이의 대우(待遇)적인 면과 젠더의 측면에서 용례를 분석하는 방법으로 고찰하였다. 그 결과 일본어의 수수동사에서 파생된 의뢰형은 화자의 젠더와 청자에 대한 대우의 정도에 따라 다양한 형태가 사용되고 있으며. 그중에서 「tekure」 「teokure」「tekudasai」「temoraitai」 형태는 의뢰형에서 청자에 대한 권유(완곡한 명령)의 의미까지를 나타내고 있었다. 그에 반해 한국어의 「아/어/여 받다」형은 문법적으로 수익태로 발달해 있지 않기 때문에 의뢰형으로서도 쓰이지 않으며 「아/어/여주다」 동사에서 파생된 형태가 의뢰형을 담당하고 있었다. 또한 한국어의 의뢰형은 일본어의 의뢰형과는 달리 화자의 젠더의 구별도 없다는 것을 알 수가 있었다. 더욱이 한국어의 의뢰형은 아직 화자의 이익을 위해서 청자에게 어떤 행동을 의뢰한다고 하는 의뢰의 본래의 의미를 가지고 있으며 청자의 행동에 대한 권유의 의미까지는 나타내고 있지 않다는 것을 알 수가 있었다. Giving and receiving verb phrases contain both the principal and the target of the benefitting act; depending on the phrase, the object of benefit may be added as well. When the principal and target of the benefitting act do not exist in a giving and receiving verb phrase, with the structure reflecting an impact by the speaker on the listener, the phrase takes on requesting characteristics. This may be because of the fact that most of the requesting modality in Japanese branch out of the giving and receiving verb, and because the requesting modality is deeply related to the benefits conferred on the speaker. The current study focuses on the treatment between the speaker and the listener, as well as the analysis of usage in terms of gender. The results indicate that the requesting expressions emanating from Japanese giving and receiving verbs display varying forms depending on the gender of the speaker and the treatment for the listener. Among them, the tekure, teokure, tekudasai, temoraitai forms take on various forms from requesting to suggesting (indirect command). On the other hand, the Korean 「-a/-e/-ye patta」 forms are not grammatically developed as a benefitting voice; as such, they are also not used to express requesting. Forms branching out from 「-a/-e/-yechuta」 verbs play the role of requesting forms. Also the requesting expressions in Korean, unlike those in Japanese, do not distinguish the gender of the speaker. Moreover, the requesting expressions in Korean retain the original requesting function of requesting the listener to do something, and they do not suggest that the listener take a certain action.

      • 學校相談에서 思考過程의 誤謬와 偏見에 關한 情報處理的 接近

        李蕙先,宋在鴻 전주대학교 교육문제연구소 1996 敎育論叢 Vol.11 No.-

        Experimental research on cognitive structures and cognitive processes has important implications for the practice of cognitive-behavior modification. The purpose of this paper was to examine some of the concepts being studied by social and cognitive psychologists in light of their potential application to counseling psychology and the practice of cognitive-behavior modification. In the information-processing perspective, the concepts of cognitive structures and cognitive processes have been examined. The concept of schemata , particularly self-schemata, was introduced. Schemata are knowledge structures that guide cognitive processing. Self-schemata are particularly important in the development and maintenance of maladaptive behavior patterns, and related to the construct of self-efficacy. The cognitive processes include cognitive strategies and excusive functioning, which may lead to the biases in judging or decision making. For counselee and counselor, various cognitive processes, particularly some shortcomings in human judgment arising from cognitive structures were presented. These include selective attention, confirmatory biases and prototype matching, use of availability and representativeness heuristics, and problems with egocentric biases and illusory correlation. Particularly, These shortcomings might affect the judgment of counselors in clinical decision making. Finally, some ways in which the counselor can minimize the bias effects of cognitive structures and resulting cognitive processes were suggested. If we can agree that counselors may be more or less biased in their clinical judgment, then the most important future step is to design research studies that can evaluate the efficacy of different inferential approaches in clinical practice. It was our intention in this paper to foster renewed interest into the nature of the problem of biases in clinical inference and judgment ; however, as our behavioral colleagues continually remind us, insight is insufficient if it does not lead to behavioral change. The time has come for the counselor to stop defensively avoiding these issues and the researcher to stop wagging a condescending finger at the hapless counselor. Rather, we need to develop and examine programs that may improve clinical judgment.

      • 젊은 성인 남자의 흡연과 혈청 지질과의 관련성

        조선,류소연,박종,강명근,김은숙,김형철,박광희,윤혜은,노희송 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

        Objectives: This study was performed to find the association of cigarette smoking and blood lipid profiles in healthy young adults. Methods: The data was collected by a self-administered questionnaire and health examination in 489 professional soldiers from 6 to 12 May, 2004. The status of cigarette smoking was classified by non-smoking, ex-smoked, ≤4.9, 5-9.9, and ≥10 pack-years. The statistical analysis were used by chi-square test, analysis of variance and analysis of covariates. Results: In status of subjects cigarette smoking, current smoking, ex-smoked, and non-smoking were 71.8%, 11.2%, and 17.0%, respectively, In distribution by amount of smoking, non-smoking, ex-smoked, ≤4.9 pack-years, 5-9.9 pack-years, and ≥10 pack-years were 17.0%, 11.2%, 37.4%, 21.3%, and 13.1%, respectively. At other confounding variables were controlled, total cholesterol and LDL-cholesterol were increased significantly when amount of smoking was increased. However, triglyceride and HDL-cholesterol did not showed statistically significant differences, Conclusion: Smoking has relevant to total cholesterol and LDL-cholesterol and it is need to perform the further study for finding how blood lipid profiles are affected its level by cigarette smoking and to find an influence of cigarette smoking on cardiovascular disease.

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