Dong-Chun Lecture : Cell-based High Content Screening (HCS) for action modes of drug targets by using systematic deletion mutants of Schizosaccharomyces pombe

( Dong Uk Kim ),( Im Seon Woo ),( Mi Sun Won ),( Young Joo Jang ),( Kyung Sook Chung ),( Han Oh Park ),( Hyang Sook Yoo ),( Kwang Lae Hoe ),( Doo Sik Kim ) 생화학분자생물학회 2005 생화학분자생물학회 춘계학술발표논문집 Vol.2005 No.-

新聞에 揭載된 韓國人 自殺記事 內容 分析

박동철,이영식,박두병,곽동일,이길홍 중앙대학교 의과대학 의과학연구소 1991 中央醫大誌 Vol.16 No.4

To analyze the suicide patterns of Koreans, a research study was conducted from the suicide cases taken from the Dong-A Newspaper from 1981 to 1990. Four hundred and eleven cases were obtained from the collected data, which were composed of 275 cases of males and 136 cases of fe-males. The age groups were classified into 6 groups for convenience, 10's, 20's, 30's, 40's, 50's, and 60's. The group differences were then compared for analysis. The characteristics in relation to the socio-demographics and family environment were conpared for analysis. Suicide types compared and analyzed by gender and age group in terms of frequency, type, time, place, method, motivation, location and size of articles, and risk factors for suicide. Sta-tistical analysis used SPSS/PC^+ for cross-tabulation analysis. 1. In relation to the rate of Koreans' suicide, male suicide rate was at least double that of fe-male(2.02 : 1). The age group of the 20's(118 cases) and 30's(96 cases) accounted for a pre-dominant rate of 52.6% of the sample. 2. The distribution of occupation of suicides showed that most were students(22.5%), followed by the unemployed(17.8%) and housewives(12.7%), retrospectively. In relation to the residency of those that had committed suicide, residents who lived in large cities accounted for the greatest number as 70.3%, Especially, females and cases in their 40's were more likely to live in large cities. In the marital status, singles were in the lead(144 cases, 33.0%). With respect to marital status by age group, cases in their 40's(17.4%) tended to have an unstable status such as divorce, separation, co-habitation, remarriage, or widowed, In birth order, the first child were the highest ones as 22.1%. 3. In relationship to the family structure, data revealed that nuclear families were the most(163 cases). Especially, males and cases in their 40's were likely to be form a nuclear familiy, while those in their 60's were from and extended family. In relation to parental survival, data showed that both parents dead were at the highest frequency as 264 cases. In case of female, loss of both parents were more frequent. 4. With respect to the frequency of recurrent suicide, data presented that 6.3% of the cases ex-perienced recurrent suicide. In case of the recurrent suicide of male(8.0%), the rate was about 2.3 times higher than of female(2.9%) 5. For the relationships of homicide and suicide, data showed that 128cases(31.2%) hurt others and attempted suicide. Among them, 96 cases(23.4%) attempted co-suicide and 32 cases(7.8%) attempted homicide others. Analyzed by the characteristics of gender and age group, 10's males were more likely to commit solo-suicide, women in their 30's or 40's commit co-suicide, and 50's commit suicide after homicide. Among the victims of homicide, family members were the most(42 cases). Analysis by age difference between the suicide partners, the cases of 30's or 40's were with family members, 20's with lovers, and 10's with their peers. 6. In relation to the annual distribution of frequency of suicide, data revealed that most cases of suicide were reported in 1990(95 cases), 70 case in 1981, 45 cases in 1982, 44 in 1983, 30 in 1986, 1987, 1989, each, the fewest cases were in 1985(14 cases). In terms of the trend of sui-cide, recently the rate of male and old cohorts over 50's has been increasing. A great number of suicide were in 1981∼1982 and 1989∼1990, the period of a treat political-economical up-heaval. On the other hand, the number of suicide was low during the period of political-economical stability of 1985 and of political thawing in 1988. These fact demonstrated that there were some relationships between political-economical change and the rate of suicide. 7. For the month of suicide, data showed that the highest frequency of cases were in May and June(21.7%), followed by 44(10.7%) in September. For the season of suicide, the fewest cases were in winter(78 cases). The cases of 10's or 20's were more likely to suicide in May and June, and those of older aged group above 50's in fall, weekend, between 1 : 00∼6 : 00 A.M. 8. With respect to the place of suicide, data presented that in most cases suicide was attempted at home(210 cases). Compared by gender, the rate of femal's suicide at home(71.3%) was remarkably higher than that of male's(41.4%). On the other hand, the rate of male's suicide in indoors was much higher(36.4%) than that of female's(15.4%). Analyzed by age groups over 50's were more likely to attempt suicide at home, 30's in indoors, 20's in the office or outdoors. 9. For the methods of suicide, 31.9% resort to intoxication followed hanging(21.9%), jumping(13.1%), burning(10.2%), CO poisoning(6.1%), gunshot(3.9%) or drowning(2.9%), Compared by gender, while females were more likely to take such passive methods as intoxication or CO poisoning, males were more likely to take rather fatal methods such as hanging, burning, gunshot. 10. In relation to the general motives of suicide, data showed that economic poverty was the lead(20.9%), followed by emotional conflict(19.2%), marital conflict(16.1%), demonstration(8.5%), health problem (6.3%), school problems(5.8%), and job problems(5.6%). Analyzed by age group, in case of 10's adolescent conflicts such as school problems, scolding of parents of teachers, mockery, and frustration were the major motivations of their suicide, in the cases of 20's hetero-sexual problems, job and demonstration were their motivators. In case of 30's marital and legal problems were the motivators, economic problems in the age of 40's, loss of objects in 50's and health problems in 60's were their major motivations of suicide. 11. Analyzed by subtypes of suicide in the socio-psychological perspective, data showed that fatalistic suicide was the most frequent(30.2%), followed by anomic suicide(29.4%), egoistic suicide(21.7%), altruistic suicide(11.2%). Whereas in case of males altruistic and egoistic suicide were relatively more frequent, in case of females fatalistic and egoistic suicide were relatively more frequent. Analyzed by age group, fatalistic suicide in the 60's, anomic suicide in the 40's, egoistic suicide in the 10's adolescents and altruistic suicide in the 20's were more frequent. 12. For the psychodynamic factors of suicide, data revealed that most cases were escape from despair and loneliness(28.5%), followed by revenge toward the objects that hurt him or her(14.8%), inferiority(12.7%), escape from a conflict situation(11.4%), altruistic(7.8%), self-punishment for guilt(6.8%), pessimism(3.9%), reunion fantasy(1.0%), and other(13.1%). Whereas the psychodynamic factors of males were altruistic and inferiority, those of females were despair and revenge. Analyzed by age group, incase of old age groups over 50's despair and loneliness were the major fcators, revenge in the 30's and 40's, altruistic in the 20's inferiority and escape from a conflict situation in the 10's were more frequent psychodynamic factors. 13. With respect to the suicide risk rescue factors, data showed that as the helpers at the time of trying suicide, family members were the most(111 cases). Family members as helpers were more frequent in the case of females and in those of 10's or 60's. While passerbys were more frequent in the case of males and in those of 50's. For the suicide notes, 17.3% left the notes behind and those in their 60's males were more likely to have a relatively higher rate of leaving motes behind. 14. In relation to the experience rate of the suicide risk factors, data demonstrated that 16.8% had a history of depression which comprised the highest rate, followed by an alcoholism history(10.0%), unemployment and retirement(7.1%), recent death of intimates and separation(4.6%), health change(3.2%). Analyzed by gender and age groups, males were more likely to have an alcoholism or depression history, those in their 40's were more likely to have an alcoholism history than those of any other age group cohorts.

확장형 칼만필터를 이용한 현수교의 감쇠성능 평가

박동욱(Park Dong-Uk),김남식(Kim Nam-Sik) 대한토목학회 2011 대한토목학회논문집 A Vol.31 No.2A

감쇠비는 현수교에 있어서 교량진동을 평가하기 위한 중요한 동적 요소 중 하나이다. 하지만, 실재 현수교에서 계측된 상시 진동신호로부터 감쇠비를 직접적으로 추정하는 것은 현실적으로 매우 어려운 일이다. 뿐만 아니라, 한정된 계측자료를 이용하여 추정된 감쇠비로부터 공기역학적 감쇠와 마찰 감쇠를 구분하는 것은 더욱 어렵다. Macdonald는 2005년 발표한 자료에서 공기 역학적 감쇠성능은 풍속에 따라 선형적으로 증가한다고 하였으며, Park등은 감쇠성능은 진동의 크기에 따라 변화할 수 있다고 하였다. 따라서 본 논문에서는 이러한 감쇠비, 풍속, 진동의 크기 사이의 관계를 연구하여, 추정 감쇠비로부터 공기역학적 감쇠와 마찰 감쇠를 구분하고자 하였다. 본 논문에서 감쇠비 추정대상으로는 전라남도 고흥에 위치한 소록대교를 선택하였으며, 감쇠비 추정에는 Hilbert 변환법을 이용한 방법과 확장형 칼만필터를 이용하였다. 또한 두 방법으로 추정된 감쇠비들을 상호 비교를 실시하였다. 그 결과, 상시진동 자료와 차량재하실험으로부터 얻어진 자료를 이용하여 추정된 감쇠비와 풍속, 그리고 가속도의 크기를 이용하여 추정 감쇠비로부터 공기역학적 감쇠 성능과 마찰 감쇠 성능의 구분이 가능하다는 것을 알 수 있었다. The damping ratio as an index of bridge vibration could be considered as one of the important dynamic characteristics of a suspension bridge. But estimating of damping ratio on an existing suspension bridge under ambient vibration condition could be a laborious task. Moreover, it is not simple to directly distinguish aerodynamic damping and friction damping from apparent damping. According to previous studies, the aerodynamic damping properties can be linearly affected by wind speed level, and apparent damping ratio can be affected by amplitude of vibration. Therefore, in this article, the relationships among damping ratio, wind speed level and amplitude of acceleration were studied for separating extract aerodynamic damping and friction damping from apparent damping. Damping ratios on Sorok Bridge, a suspension bridge which is a located in Go-Heung, Korea, were estimated by two different methods as using Hilbert transform and extended Kalman filter which were well known as effective estimation methods for non-linear state. It was possible to distinguish aerodynamic damping and friction damping from apparent damping using averaged normal components of wind speed, RMQ values of acceleration, and estimated damping ratios from wind-induced vibration responses and vehicle loading responses.

Event Mean Concentrations (EMCs) and First Flush Characteristics of Runoff from a Public Park in Korea

Jung, Jae-Woon,Park, Ha-Na,Yoon, Kwang-Sik,Choi, Dong-Ho,Lim, Byung-Jin The Korean Society for Applied Biological Chemistr 2013 Applied Biological Chemistry (Appl Biol Chem) Vol.56 No.6

Characteristics of non-point source (NPS) pollution runoff from a public park in Gwangju, Korea were investigated. Results exhibited the highest pollutant concentrations at the start of the rainfall events due to their build-up and wash off processes. The average event mean concentrations (EMCs) were 27.8, 7.2, 56.3, 7.5, and 0.84 mg/L (range: 4.2-54.8 mg/L) for COD, (0.5-20.8 mg/L) for TOC, (22.3-138.4) for SS, (1.4-18.5 mg/L) for T-N, and (0.17-2.02 mg/L) for T-P, respectively. The study site presented a strong first flush effect for most rainfall events. However, no first flush effect was observed in rainfall events with small rainfall factors (e.g. intensity, amount, and runoff depth). On the other hand, the ratios of total pollution loads discharged by the first 20% of runoff volume were 32% for COD, 34% for TOC, 36% for SS, 42% for T-N, and 50% for T-P. Especially, $MFF_{20}$ (mass first flush) values of T-N and T-P were larger than those of other pollutants (COD, TOC, SS), indicating that T-N and T-P are easily transported by stormwater runoff from the public park. First flush management of T-N and T-P, therefore, is required for efficient water quality management of the public park.

골수 검사상 양성 혈구 탐식 조직구가 나타난 소아의 임상적 고찰

박진아,박주영,박지민,박샛별,김흥식,전동석,Park, Jin A,Park, Joo Young,Park, Ji Min,Park, Seat Byoul,Kim, Heung Sik,Jeon, Dong Seok 대한소아청소년과학회 2002 Clinical and Experimental Pediatrics (CEP) Vol.45 No.8

목 적: 혈구 탐식 조직구 증식증은 양성 질환으로는 드물게 치명율이 높은 질환으로, 발열, 간비장 종대, 림프절 종대 등의 증상이 있고, 검사 소견에서 양성의 혈구 탐식 조직구가 나타난 경우 진단되나 치료가 혼란스러운 경우가 많다. 골수 검사상 양성의 혈구 탐식조직구가 나타난 예들의 임상적 특징을 분석하여 진단 및 치료 방향과 예후 판정에 도움이 되고자 이 연구를 시행하였다. 방 법 : 1995년 1월부터 2001년 11월까지 계명대학교 동산병원에서 골수 검사상 양성의 혈구 탐식 조직구가 나타난 환아 30례를 대상으로, 특징적 임상 증상, 진찰 소견, 혈액 검사 소견, 골수 검사 소견, 치료 방법과 예후에 대하여 임상 기록지를 후향적으로 분석하였다. 또한 골수 도말에서 혈구 탐식 조직구의 수에 따라 a few, some, many로 나누어 환아의 예후와 비교하였다. 결 과 : 골수 검사상 양성 혈구 탐식 조직구를 보인 예들을 분석한 결과 이들의 연령 분포는 2개월에서 15세로, 평균 연령은 5.6세였고, 남녀비는 2.3 : 1로 남아가 많았다. 입원 당시 증상으로는 발열이 가장 많았으며, 호흡기 증상, 위장관 증상 등의 순이었고, 평균 발열 기간은 19.5일이었으며, 진찰 소견은 간비종대, 피부 발진, 림프절 비대 순으로 많았다. 혈액 검사 소견상 백혈구 감소증이 23례(76.7%)로 가장 많았고, 혈소판 감소증이 16례(53.3%), 빈혈이 15례(50.0%), 간기능 검사 이상이 15례(50.0%)로 나타났다. 기저 질환으로 급성 림프구성 백혈병, 악성 림프종 등 면역 저하된 상태가 5례였고, 건강했던 경우가 25례 였으며, 관련 질환의 종류로는 패혈증, 폐렴, 전염성 단핵구증 등의 순이었고, 원인으로는 세균이 많았으며, 바이러스로는 EBV가 4례였고, candida가 1례였다. 골수 도말 소견상 세포 충실도가 정상이 25례(83.3%)였고, 5례(16.7%)에서 감소되어 있었으며, 혈구 탐식 조직구의 수에 따라 분류하였을 때, some이 15례(50.0%), many가 9례(30.0%), a few가 6례(20.0%)이었다. 치료는 보존 요법, 항생제와 항바이러스제, 항진균제, 면역 글로불린, steroid, etoposide, cyclosporine 등의 병용 요법을 시행하였다. 사망율은 30명 중 8명으로 26.7%였으며, 연령이 낮은 군과 혈구 탐식 조직구 수가 some 이상인 경우에 사망률이 높았다. 결 론 : 고열, 간비종대, 범혈구 감소증과 간기능 이상 등의 소견을 보이는 환아에서 조기에 골수 검사를 시행하여 혈구 탐식 조직구가 보일 때, 원인 치료 및 대증 요법과 함께 면역 화학 요법을 시행하는 것이 예후에 도움이 될 것으로 생각되며, 골수 소견과 예후와의 관계는 지속적인 연구 관찰이 필요할 것으로 사료된다. Purpose : The aim of this study is to find a method to diagnose and treat children who showed benign hemophagocytic histiocytes in bone marrow examination. Methods : We analyzed the clinical data of thirty patients retrospectively who showed benign hemophagocytic histiocytes in bone marrow examination from January 1995 to November 2001 at Keimyung University Dong-san Hospital. Bone marrow histiocytes were classified into a few, some, and many according to the number of histiocytes comparing with the white cells. Results : The age of thirty patients ranged from two months to 15 years. The median age was 5.6 years with male predominance(2.3 : 1). The most frequent clinical manifestation was fever; others were respiratory symptom, hepatosplenomegaly, lymphadenopathy and skin rash(in order of frequency). Common laboratory findings were leukopenia, thrombocytopenia, anemia and abnormal liver function test. Infection was present in 30 patients; causative organisms were documented in 15 patients, and bacterial infection was more common. Epstein Barr virus was the cause of infection in four patients. Bone marrow examination showed a few(20.0%), some(75.0%) and many(30.0%) hemophagocytic histiocytes. Combination immunochemotherapy including immunoglobulin, steroids and cyclosporine were helpful in 22 out of 30 patients. The mortality rate was high in young patients who showed some to many hemophagocytic histiocytes. Conclusion : Bone marrow examinations and early detection of histiocytes will be helpful in children who have fever, hepatosplenomegaly and abnormal liver function test. Immunochemotherapy were helpful and further investigation will be needed for the detection of the relationship between the bone marrow findings and prognosis.

우리나라에서 솔껍질깍지벌레의 분포확산

임유진,이상명,김동수,김준범,최광식,이신혜,박정규,이동운,Lim, Eu-Gene,Lee, Sang-Myeong,Kim, Dong-Soo,Kim, Joon-Bum,Lee, Shin-Hye,Choi, Kwang-Sik,Park, Chung-Gyoo,Lee, Dong-Woon 한국응용곤충학회 2012 한국응용곤충학회지 Vol.51 No.1

솔껍질깍지벌레는 우리나라 곰솔림의 주요한 해충의 하나이다. 본 연구는 우리나라에서 솔껍질깍지벌레의 분포를 알아보기 위하여 7개도 3개 광역시, 91개 시군구, 686 읍면동의 해송림에서 2010년 밀도를 조사하였다. 5개도 2개 광역시에서 솔껍질깍지벌레가 서식하고 있었는데 시군구별로는 조사대상의 64.8%인 59개 시군구에서 서식이 확인되었다. 솔껍질깍지벌레의 분포는 남해안 전역과 동해안의 포항, 서해안의 충남 보령지역까지 분포하였다. 충북과 대전광역시 및 제주도에서는 솔껍질깍지벌레의 분포가 확인되지 않았다. 부산지역은 16곳의 모든 구에서 솔껍질깍지벌레가 분포하였고, 시군 단위에서는 전남 해남군의 솔껍질깍지벌레 평균밀도가 1.713마리/0.785 $cm^2$로 가장 높았으며 읍면동 단위에서는 해남군 송지면이 6.36마리/0.785 $cm^2$로 가장 높았다. 곰솔 가지 내의 솔껍질깍지벌레 밀도와 솔껍질깍지벌레가 서식하고 있는 빈도와는 높은 상관관계가 있었다(상관계수=0.89). The black pine bast scale, $Masucoccus$ $thunbergianae$ (Hemiptera: Margarodidae), is a serious pest of the Japanese black pine, $Pinus$ $thunbergii$, in Korea. The distribution of the black pine bast scale was examined, looking overall at 686 towns (eup), townships (myeon) or neighborhoods (dong). There were Japanese black pine ($Pinus$ $thunbergii$) forests in 91 cities, counties (gun) and borough (gu), in seven provinces and three metropolitan cities during 2010. Black pine bast scale were found in 64.8% of cities or counties or borough (59) in 7 provinces and 3 metropolitan cities, and were distributed in all South Costal regions, Pohang in East Costal region and Boryeong in West Costal region. Chungcheongbukdo, Daejeon and Jeju did not have black pine bast scale. All the gu regions in Busan had black pine bast scale, of which the area with the highest prevalence was Haenam in Jeollanamdo (1.713 crawlers/0.785 $cm^2$). Songji-myeon had the highest occurrence rate (6.36 crawlers/0.785 $cm^2$) from the towns, township and dong. The density of black pine bast scale in twigs was highly correlated with percentage of the sample with scale (Correlation coefficacy=0.89).

국립공원 관리를 위한 해양생태계 장기 모니터링 프로그램의 발전 방향

이채린(Chae-Lin Lee),유재원(Jae-Won Yoo),정병관(Byungkwan Jeoung),김창수(Chang-Soo Kim),안동식(Dong-Sik Ahn),김성태(Sungtae Kim),성은주(Eun-Ju Sung),김성현(Sung-Hyun Kim),정수영(Su-Yeoung Jeong),박영석(Young-Seuk Park) 국립공원연구원 2021 국립공원연구지 Vol.12 No.2

생태계 변화의 모니터링은 효율적 생태계 관리를 위한 기초 정보 수집을 위해 중요한 과정이다. 많은 생태 현상과 그 과정은 오랜 시간에 걸쳐 진행되므로 국립공원의 지속적인 보전 및 효율적 관리를 위해 생태계 모니터링은 장기적으로 이루어질 필요가 있다. 본 연구는 국내외 장기 모니터링 프로그램 사례 분석을 통해 성공적인 장기 모니터링을 위한 방법으로써, 최적화된 모니터링 설계, 표준화된 운용방안 마련, 인적 자원 및 DATA 관리 체계 수립, 안정적인 재정 마련 및 후속지원 등을 제시하였다. 이를 바탕으로, 현재 10년 넘게 수행되고 있는 ‘HS호 유류유출 사고 해역 장기 모니터링 프로그램’의 발전 방향으로 적응형 모니터링 방식이 적용된 표준화된 프로토콜의 정립, QA/QC와 지속적인 자료 관리, 조사 항목의 연계성 강화 등의 구체적 방안을 제안한다. Monitoring ecosystem changes is an important process for collecting basic information for ecosystem management. Since many ecological phenomena and their processes take place over a long period of time, it is necessary to conduct long-term monitoring of ecosystems for the continuous conservation and efficient management of national parks. This study suggested an optimized monitoring design, standardized operation plan, human resource and data management system, stable financial preparation and follow-up support as methods for successful long-term monitoring through case analysis of domestic and foreign long-term monitoring programs. Based on this, it proposes specific measures such as establishing a standardized protocol with adaptive monitoring methods, continuous data management with QA/QC, and strengthening the linkage of investigation items in the development direction of the “HS oil spill accident long-term monitoring program” that has been conducted for more than a decade.

외국인지분율이 기업가치에 미치는 영향

박천식,윤동훈 경북대학교 경제경영연구소 2007 經商論集 Vol.34 No.2

본 연구는 외국인 투자자들이 우리나라 기업들의 기업가치에 미치는 영향에 대하여 검토하고자 한다. 기업가치와 외국인투자자지분율의 관계를 분석하기 위해 1996년부터 2006년 사이에 걸친 금융업을 제외한 405개 기업들을 대상으로 외국인투자자지분율은 기업가치에 정(+)의 상관관계를 가질 것이라는 가설을 검증하기 위해 기업가치의 대용변수로써 Tobin’s Q 비율과 주당순자산비율을 설정하였고, 설명변수로는 외국인투 자자지분율을 사용하였으며 또한 기업규모, 재무레버리지비율, 총자산이익률, 자기자본 이익률, 연구개발비비율, 광고비비율, 매출액증가율을 통제변수로 사용하여 상관분석 및 회귀분석을 실시하였다. 검증 결과로 외국인투자자지분율과 기업가치는 정(+)의 상관관계를 나타냈고 외국인투자자지분율은 전기의 Tobin's Q 비율 기업규모 광고비비율과 정(+)의 효과가 있고, 주당순자산비율, 재무레버리지비율과는 부(-)의 효과가 있는 것으로 나타났다. In this study we examined the influence of the share of foreign investors on corporate value of which proxy variable is input Tobin's Q and Price to Book Ratio(PBR) in turn. The data of 405 corporations listed between 1996 and 2006 excluding financial companies is analysed in this study, the methodology such as correlation and regression analysis is used, The hypothesis that foreign investor share ratio has a positive effect on corporate value was established, and to verify the hypothesis, a regression model was built. As dependent variables of the regression model, Tobin Q ratio, PBR were used, and foreign investor share ratio as independent variable and corporate size, financial leverage ratio, return on asset, return on equity, research and experimental costs ratio, marketing and advertising costs, and net sales growth rate as control variables were used. And multiple regression analysis model was adopted for verification. The findings in empirical analysis of this study are as follow. First, we found that Tobin's Q and PBR have positive relationships with foreign investors' share ratio. In other words, corporations with higher foreign investor share ratio have increased corporate value. Second, variables that affect foreign investor share ratios were examined. The results showed that the Tobin's Q, corporate scale, marketing and advertising costs at (t-1) have significant positive effects on foreign investor share ratio at t, and PBR and financial leverage ratio at (t-1) has a significant negative effect on foreign investor share ratio at t.

麗水沿海 漁場의 夏季 海況에 관하여

朴容石,金東守,金在植 여수대학교 1988 論文集 Vol.2 No.-

The oceanic condition characteristic in the coastal fishing ground of Yeosu is investigated by the oceanographic observation in summer, 1988. The results to analyze the data obtained from this observation are as follows: (1) The coastal surface water accepted influence of land is high temperature and low salinity, and the off shore water and bottom water are low temperature and high salinity. (2) In summer the eddy current and discontinuity appeared in the fishing ground of the set net, so a good catch expected in this fishing ground. (3) In summer the sharp thermocline appeared between the depth of 30m and 40m in coastal fishing ground. This thermocline prevents vertical mixing.

발달성 고관절 이형성증 환자에 발생된 고도의 탈구에 대한 전자하부 단축 절골술을 통한 인공고관절 치환

박명식,서동주,박종혁,오상수,황병연 대한고관절학회 2004 Hip and Pelvis Vol.16 No.1