급성전골수성백혈병에서 백혈구성분채집술에 이은 치명적인 뇌출혈 2예

오윤정,박소윤,김윤정,한동석,김현수,최진혁,남동기,임호영,김효철,주희재 아주대학교 의과학연구소 1998 아주의학 Vol.3 No.1

The aim of this study is to report 2 cases of acute promyelocytic leukemia who died from intracranial hemorrhage following leukapheresis and to provide proper preventive measures against hemorrhage following leukapheresis. From 1994 to 1997, a total of twenty-six patients with leukemia underwent leukapheresis to control hyperleukocytosis at Ajou University Hospital. Two patients with acute promyelocytic leukemia received all-trans retinoic acid but developed drug-induced hyperleukocytosis. Shortly after leukapheresis, they died from intracranial hemorrhage. The risk factors for fatal hemorrhage are thought to be coexisting disseminated intravascular coagulation(DIC), thrombocytopenia aggravated by leukapheresis, exacerbated coagulopathy related to mechanical trauma through leukapheresis and the excess use of citrate during leukapheresis. To reduce the risk of the bleeding associated with leukapheresis, it is necessary to replace platelet sufficiently before and after leukapheresis and to give calcium to correct coagulopathy induced by excess citrate which is used as anticoagulant as well as the correction of disseminated intravascular coagulation.

광학 마이크로패턴의 광산란 Simulation에 관한 연구

윤철용,현동훈,유경선 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-

This paper has to gain visual effect as light scattering by various angle and phase using optical micro pattern for metal. Also applying to optical micro pattern for metal surface design by developing optical technology and ultra-precision machining technology.

석유화학 공정의 가상사고 시나리오 유형분석

윤동현,강미진,이영순,김창은 한국안전학회 2003 한국안전학회지 Vol.18 No.3

This paper presents a set of typical pseudo-accident scenarios related to major equipments in petrochemical plants, which would be useful for performing such quantitative risk analysis techniques as fault tree analysis, event tree analysis, etc. These typical scenarios address what the main hazard of each equipment might be and how the accident might develop from an "initiating event". The proposed set of accident scenarios consists of total thirteen (13) scenarios specific for five (5) major equipments like reactor, distillation column, etc., and has been determined and screened out of one hundred and twenty-five (125) potential accident scenarios that were generated by performing semi-quantitative risk analysis practically for twenty-five (25) petrochemical processes, considering advices from the operation experts. It is assumed that with simple consideration or incorporation of plant-specific conditions only, the proposed accident scenarios could be easily reorganized or adapted for the relevant process with less time and labor by the safety engineers concerned in the petrochemical industries.

데이타베이스산업과 저작권

윤영철,변동현,박흥수 연세대학교 언론연구소 1992 언론 사회 문화 Vol.- No.2

음향방출을 이용한 콘크리트 부재의 미시적 파괴특성의 온라인 모니터링

윤동진,이진경,이준현 韓國非破壞檢査學會 1999 한국비파괴검사학회지 Vol.19 No.1

콘크리트는 다상(multi-phase)의 재료로서 구성되어지는 복합재료의 일종으로써 준취성(quasi-brittle)적인 재료적 특성을 가지고 있기 때문에 실제 복잡한 미시적 파괴특성을 나타낸다. 따라서 콘크리트 구조물의 안전성 확보를 위해서는 먼저 하중의 증가에 따른 콘크리트 내부의 변형특성 및 미시적 파손기구를 파악하여야 하며, 특히 실제 구조물에 있어서는 이들 특성들을 비파괴적으로 상시(on-line) 모니터링 하여야 할 필요가 있다. 따라서 본 연구에서는 3점 굽힘 하중을 받는 콘크리트 부재의 미시적 파손기구 및 각 파손기구에 대한 AE 특성을 명확히 함으로써 콘크리트 부재의 미시적 손상 및 파괴 특성을 비파괴적으로 평가하고 AE 발생원 위치 추정 기법을 이용하여 균열 발생 및 진전거동을 평가하였다. Since concrete is an inhomogeneous material consisting of larger aggregates and sand embedded in a cement paste matrix, it relatively shows a complex failure mechanism. In order to assure the reliability of concrete structure, microscopic fracture behavior and internal damage progress of concrete under the loading should be fully understood. In this study, an acoustic emission(AE) technique has been used to clarify microscopic failure mechanism and their corresponding AE signal characteristics of concrete under three-point bending test. In addition 2-dimensional AE source location has been performed to monitor the progress of an internal damage and the successive crack growth behavior during the loading. The relationship between AE signal characteristics and microscopic fracture mechanism is discussed.

The Relationship among Engagement in Workplace Learning Activities, Openness to Learning, and the Extent of Participant Involvement in Informal Learning

Yoon,Dong-Yeol,You,Jieun,Yun,Wi Seok,Hyun,Sunhae 한국인적자원관리학회 2011 인적자원관리연구 Vol.18 No.4

일터학습에 있어서 비공식학습의 중요성이 대두함에 따라, 많은 기업들은 직원들의 비공식 학습을 촉진할 수 있는 다양한 학습전략응사용하고 있다. 기존의 연구들은 기업 내 공식학습과 비공식학습은 상호 연관되어 있어, 공식학습을 제공할 경우 비공식학습도 동시에 활성화된다고 주장한다. 본 연구는 직원들이 기업에서 행해지고 있는 일터학습에 참여하는 정도가 비공식학습활동에 어떠한 영향을 미치는지 연구함으로써, 일터학습의 참여도와 비공식학습의 관계를 알아보고자 하였다. 일터학습에 참여하고 있는 제약회사의 직원들을 대상으로 한 설문조사에 대하여 회귀분석을 실시한 결과, 일터학습에 참여하는 것 자체는 직원들이 비공식학습에 몰입하는 정도에 유의미한 영향을 미치지 못하는 것으로 나타났다. 특히 실천공동체와 온라인 학습의 경우 비공식학습에 부정적 영향을 미치는 것으로 나타났다. 이는 기업이 일터학습을 제공하더라도, 체계적인 형태를 갖추지 못했거나 직원들 간의 상호작용을 촉진하지 못할 경우 일터학습이 오히려 비공식학습을 저해할 수 있다는 것을 보여준다. 그러나 개인의 학습 개방성은 비공식학습의 정도에 영향을 미치는 것으로 나타나, 일터학습의 참여도가 비공식학습의 정도에 미치는 영향에 조절효과를 보이는 것으로 나타났다. 끝으로 연구결과는 관리자 직급에 있는 근로자들의 경우 그렇지 않은 직원들에 비하여 비공식학습활동에 더 많이 참여하고 있다는 것을 보여준다. 관리자 직급의 근로자들은 학습에 대한 경험이 풍부하고, 학습의 필요성에 대해서도 충분히 인식하여 비공식학습활동에도 적극적으로 참여하고 있다고 볼 수 있다. 따라서, 기업 내에서 비공식학습을 활성화시키기 위하여, 종업원들에게 일터학습을 제공하고 이것에 참여하도록 유도하는 것뿐만 아니라, 직원들 스스로 학습에 참여할 수 있는 개방적 태도를 지닐 수 있도록 지원하는 것이 중요하다는 것을 보여준다. Informal learning in the workplace is becoming more important for improving employees’ competencies and organizational performance. Many business organizations use a variety of workplace learning strategies in order to facilitate informal learning among employees. Research on workplace learning explains that formal learning and informal learning interrelate and facilitate each other. This study investigated the relationship among engagement in workplace learning activities, openness to learning, and the extent of participant involvement in informal learning. As a result of quantitative research in a pharmacy company, this study showed the following: (a) openness to learning affects participant involvement in informal learning more than engagement in workplace learning activities does; (b) among types of workplace learning, communities of practice negatively influence internal informal learning, and web-based learning also has a negative effect on involvement in internal, external informal learning and informal learning among newly hired employees, but traditional classroom training positively affects participants’ involvement in informal learning among new employees; and (c) employees at the managerial level involve in informal learning activities more than other employees. These results suggest that business organizations and corporate management should support and facilitate employees to learn with openness as well as provide them with workplace learning opportunities.

머리염색이 인체에 미치는 영향

윤형식,황성호,이현륭,김수호,박연석,권낙현,정호진,김동훈,노현주,홍성호,박병찬,이관,정해관 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

일상생활에서 모발염색은 흔히 접할 수 있는 미용의 한 종류로 특히 젊은층을 중심으로 폭발적으로 유행하고 있다. 염색을 위항 사용하는 약제는 표백제와 발색제 등 각종 화학약품이 사용되고 있으나 이로 인한 건강장해에 대한 연구는 그리 많지 않다. 저자들은 염색이 인체의 모발건강에 미치는 영향을 파악하기 위하여 염색과 관련된 주관적 증상과 모발의 변화에 대한 실험적 연구를 시행하였다. 동국대학교 경주 캠퍼스 재학생 80명을 대상으로 설문조사를 시행하여 염색 유 ·무 및 염색 후에 경험한 증상에 대해 설문 조사하였고, 의과대학 재학생 46명을 대상으로 피부 반응 테스트를 실시하였다. 또한 염색 전후의 모발 탄성도를 측정하였고 모발의 상태를 파악하기 위해 전자 현미경검사를 실시하였다. 설문조사 결과 염색 전에 비하여 염색 후 안구혼탁, 안구건조, 시력저하, 발진 및 접촉성 피부염, 모발손상, 모근손상 등의 증상을 더 많이 경험한다고 호소하였다(p<0.05). 모발손상과 모근손상은 헤어드라이어 사용 빈도에 따라 증가하는 것으로 조사되었다(p<0.05). 피부반응검사에서 가려움증이 가장 많은 증상이었으며 이는 여성보다는 남성에서 높은 것으로 조사되었다. 염색 전후의 모발장력은 염색 전 134.5±10.37g, 염색 128.0±30.69g, 염색 이틀 후 112.5±19.69g으로 나타났다. 염색 전후의 모발의 전자현미경 케라틴 층이 현저히 감소하고 모발이 가늘어지는 차이를 보였다. 염색은 모발손상, 모발 케라틴 손상 및 모근 손상, 발진 및 접촉성 피부반응, 안구혼탁, 안구건조, 시력 저하를 유발한다. 따라서 염색약으로 인한 손상에 대한 주의와 예방이 필요하다고 생각한다. 예방대책으로 염색 전 피부테스트를 통한 적합성 여부를 판단하는 것이 필요하며 가급적 염색을 피하는 것이 좋을 것이다. 염색약에 발암물질이 포함되어있다는 보고도 있어 염색 제조사의 철저한 실험과 염색 물질의 선별이 염색으로 인한 부작용을 최소화하는데 중요한 역할을 할 것이다. Hair coloring has became one of the most popular cosmetic activities to younger generations during last decade. However, there are few studies on the health effect of widespread use of chemical dyes. This study was conducted to study the effects of hair coloring dye on hair and other systems. We conducted a questionnaire survey of 80 persons in Kyongju campus, Dongguk University. We have done open patch skin test on 46 medical students. We also conducted scanning electron microscopy to examine the hair strength and structure before and after hair coloring process. Injury of hair and hair bulb, contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity were the main symptoms complained after hair coloring (p<0.05). Injury of hair and hair bulb were increased by frequency of hair-dryer use(p<0.05). In open patch test, pruritus was complanined by more than half of the subjects. Mean strength of hairs before and after hair coloring was as follows; 134.5 (SD 10.37)g before hair coloring, 128.0 (SD 30.69)g immediately after hair coloring, and 112.5 (SD 19.69)g after two days. The scanning electron microscopic findings of hair surface before and after hair coloring showed decreased keratin layer and thinning of the hair. Hair coloring induces injury to hair, its keratin layer, and hair bulb as well as contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity. Therefore, we think that precaution is needed in use of hair coloring dye. To prevent complications induced by hair coloring dye, it is necessary, especially to those with allergy or skin disorders, to perform skin test before action and avoid hair coloring whenever possible. Longterm health effects of hairdye should be studied and manufacturing companies should try to minimize complications induced by hair coloring dye.

주행속도에 따른 부상마그네트의 특성을 고려한 상전도 자기부상시스템의 부상제어에 관한 연구

玄東石,洪正杓,鄭因城,許眞,尹相伯 창원대학교 공작기계기술연구센터 1999 연구업적집 Vol.1 No.1

A collective controller for electromagnetic suspension (EMS) system considering the speed characteristics of electromagnets is presented. The speed characteristics of the electromagnet are analyzed by finite element method (FEM) and Neural Network algorithm is used for the controller considering speed. The proposed controller is examined and the dynamic characteristics are compared with those of other controllers. The simulation results show that proposed controller has a better performance at high speed.

공간고조파해석법을 이용한 영구자석 선형 동기전동기의 특성해석

尹相伯,洪正杓,玄東石,鄭因城 창원대학교 공작기계기술연구센터 1999 연구업적집 Vol.1 No.1

This paper presents a two dimensional analytical method of a permanent Magnet Linear Synchronous Motor(PMLSM) based on the concept of space harmonic The air gap flux densities due to permanent magnets and primary current are calculated separately, and the resultant air gap flux density is obtained by superposition of those, Maxwell's stress tensor is used to calculate thrust and normal force. The static thrutst and normal force according to exciting current and power angle are calculated, and the harmonics of the thrust are analyzed using discrete Fourier transform In order to verify the validity of the proposed analytical method, we make a test facility and compare the analysis results with the experimental ones.

한국과 스웨덴의 생활체육에 관한 비교 연구

윤상화,남동현 龍仁大學校 體育科學硏究所 1998 體育科學硏究論叢 Vol.8 No.1

This study is with regard to the physical Education and Sports of Sweden, and has the purpose to give the assistance to the development of Physical Education and Sports in Korea, by use of the characteristics in the Physical Education and Sports of Sweden. As the results of this study, we would like to suggest the under-mentioned for the development of Korea Physical and Sports. 1. The Korean Physical Education and Sports Program must use the geographical conditions. 2. We must its importance to the Social Physical Education from the administration based on the Elite Physical Education, and thus it is necessary to make it as 2 base in the Korean Physical Education. 3. We make promote the Physical strength from the young times and guide to be interested in the use of leisure by the strict performance of School Sports Time. 4. The person graduated from the Dept. of Social Physical Education of each University or Social Sports Instructor are sure to be dispatched in the General Sports Field, and thus it is necessary to take charge of the sports guidance for the public sincerely. 5. The Social Sports Class of Health Class related to the housewives is operated in each Village Ward Office or upon the school during the vacation, and thus progress the concern on Physical Education, and acknowledge the service credits for the students who perform the voluntary service in the program, and thus it is necessary to promote the participation degree. 6. We are out of the department which takes charge of the formal Social physical education, and thus it is necessary to make the research part for the national-wide network. 7. The law on promotion of national sports is changed to the compelling law, and then it is strongly required which the Government shows the powerful will on the Sports Making as Living.