아르곤 레이저에 의한 복합레진의 중합시 물성 변화에 관한 연구

김덕,민병순,최호영,최기운,박상진 大韓齒科保存學會 1998 Restorative Dentistry & Endodontics Vol.23 No.1

After polymerizing composite resin with argon laser and visible light, four test, to be concretelv, measurement of compressive strength using Instron testing machine, surface microhardness using Rockwell hardness tester, quantitative analysis of residual monomer using HPLC and analysis of degree of conversion using FTIR, were accomplished. Test groups were a sort of specimen with 3mm diameter, 4㎜ thickness for measuring compressive strength, two sort of specimen with 7mm diameter, 2mm and 3㎜ thickness for measuring surface microhardness, quantitative analysing of residual monomer after curing and measuring the degree of conversion, each were divided by according to the condition of light exposure. In case of argon laser. in 1.0W and 0.5W output. the exposure time for specimen were 5 sec, 10 sec respectiyely. In case of visible light, the exposure time obtained. 1. Compressive strength of composite resin was the highest in the group of 1W output, exposing for 10 sec with argon laser, followed by the group of 0.5W, exposing for 10 sec with argon laser, the group of exposing for 40 sec with visible light. But there were statistically no significant difference between these three groups(p>0.05). 2. Surface microhardness of composite resin wasn't significantly affected by light curing conditions. 3. BIS- GMA within residual monomer was least detected in the group of exposing for 40 sec. TEGDMA was least detected in the group of 1W output, exposing for 10 sec with argon laseboth 2㎜ and 3㎜ thickness specimen. 4. The degree of conversion of all groups in the 2㎜ thickness specimen were more than 5%, similar to each other but in the group of 1W, exposing 10 sec with argon laser the degree of conversion was highest in the 3㎜ thickness specimen. 5. Argon laser could make composite resin to has similar properties with 25% lesser exposure time than visible light.

광중합형 글라스아이오노머 시멘트와 복합레진의 전단결합강도에 관한 연구

김덕,민병순 大韓齒科保存學會 1994 Restorative Dentistry & Endodontics Vol.19 No.2

광중합형 글라스아이오노머 시멘트와 복합레진과의 전단결합강도에 관한 연구

김덕,민병순,최호영,박상진,최기운 慶熙大學校 齒科大學 1994 慶熙齒大論文集 Vol.16 No.1

The purpose of this study is to evaluate of shear bond strength of light-curing composite resin to light-curing glass ionomer cement. Composite resin and glass ionomer cement have been widely used as an esthetic filling materials in dental clinics. To achieve better clinical results, sandwich technic was developed with conpensating for disadvantages of these two materials. Especially, light-curing glass ionomer cement provided greately improved bonding strength of teeth or composite resin, and then excellent clinical results can be acquired. In this study, 6 commercial light-curing glass ionomer cements(3 commercial restorative materials Fuji II LC, Vanglass VLC, Vitremer, and 3 commercial lining materials : Fuji Lining LC, Baseline VLC, Vitrebond) were devided two groups. According to manufacturer's appointment, no surface treatment was referred to N groups. Supposing of clinical practice, surface grinding with water ;spray at 320 grit sand paper, 40 seconds etching with 37% phosphoric acid, 20 seconds washing 20 seconds air drying was referred to E groups. Totally 12 experimental groups were devided, and all 120 specimens from 10 specimens of each groups were made. After light-curing composite resin was bonded to right-curing glass ionomer cement, shear bond strength was tested by Instron universal testing machine between glass ionomer cement and composit resin. The data were analyzed statistically by Student's t-test and ANOVA. The obtained results were as follows; 1. In light-curing glass ionomer cement, restorative materials showed higher shear bond strength to composite resin than lining matenals(p<0.05). 2. Variglass VLC of restorative material group and Baseline VLC of lining material group have highest shear bond strength to composite resin(p<0.001). 3. In light-curing glass ionomer cement:, surface grinding and acid etching reduced shear bond strengthto composite resin(p<0.001). 4. VGN group is highest shear bond strength to composite resin, VBE group is lowest shear bond strength to composite resin(p<0.001).

휠체어 검도 경기를 위한 경기규정에 관한 연구

김영학,공병덕,이병기 龍仁大學校 武道硏究所 2002 武道硏究所誌 Vol.13 No.1

The purpose of this study was to build revised game rules for wheelchair Kumdo for the physically challenged confined to wheelchair, after teaching 10 people how to play Wheelchair Kumdo. It's ultimately intended to determine whether or not the revised game regulations were appropriate and workable and ultimately to promote Wheelchair Kumdo. There Kumdo trainees of the 4th, 5th and 6th grades respectively and three physically different people were coached to draft game rules in three phases, and they were finalized through an advice of a specialist. And then five disabled Kumdo trainees, who included three of the 3rd grade and two of the 2nd grade, learned the regulations for a month to find out their adequacy. As a result of interviewing them and analysing the collected data, the following findings were given: First, the stadium should have a flat floor, by using proper materials such as wood or concrete, to guarantee the smooth operation of wheelchair. It should be in a square form and 11 meter or higher in length. The starting lines should bo marked 'T' on both sides from the central line, and the upper parts of the marks should face each other. There should be 1.7m distance between the central and starting lines and 2 meter or higher extra spaces in the external sides. Second, the bamboo sword should be redesigned to be 114cm in length and 370g in weight to fit in wheelchair Kumdo. Third, among Kumdo equipment, Homyun(護面, Headgear), part of HoKu(Protection-equipment, 護具), should be made of lighter materials, thicker in the head part, and easy to wear. Gab(甲, Chest-guard) should have a sort of shock absorber in it, and a remodeled Hoku that has no wings on both sides should be used. To prevent wheelchair from shock and ensure its safety, a Quickie All Court model should be selected, and each contestant should wear a suit of different color that has his or her name on the shoulder portion. Fourth, each game should run four minutes, constituted by two periods, and a break time should be given. The judgment should be made without no extra time, and a contestant who hits one of the due points ahead of the other should be a winner. Fifth, as for Yuhyo-Geokja(有效擊刺, Point), action against the head, wrist or waist should be considered Geokja(擊刺, Strike), and one against the chest part should be regarded as Jabu(刺部, Stab). Based on the above-mentioned findings, there are some suggestions about wheelchair Kumdo games: First, as games could be held out in the field, outdoor programs should be attempted. Second, every game is divided into the first and second periods, and coaches need to develop programs suitable for the two-part competition to give better guidance. Third, general Kumdo equipment isn't suitable for wheelchair Kumdo, and a lot of research efforts should urgently be dedicated to developing separate equipment for that.

Polylysine을 입힌 배양면이 GH₃ 뇌하수체 종양 세포에 미치는 영향에 관한 연구

김정진,백상호,황덕호,황영일,이왕재,이병란 대한해부학회 1998 Anatomy & Cell Biology Vol.31 No.3

Simple Sequence Repeat Primer에 의한 딸기의 Genomic DNA 분석

양덕춘,최성민,김무성,민병훈 경희대학교 생명자원과학연구원 2002 硏究論文集 Vol.22 No.-

본 연구는 진핵세포에 널리 산재되어있는 repeat sequence를 primer로 사용하여 딸기의repeat sequence 좌위를 증폭시켜서 분석하고 이를 같은 종일지라도 지역간의 차이로 인한 환경의 변화 또는 재배방법의 차이에 의해서 일어나는 변이를 분석하는 방법에 활용할 수 있도록 하기 위하여 수행하였다. GGC repeat sequence의 딸기 genomic DNA에 존재여부를 판명하기 위하여 (GGC)_(6) probe를 DIG을 사용하여 labeling하여 딸기 genomic DNA에 hybridization한 결과 확실한 spot이 나타났다. 또한 repeat sequence로 이루어진 UBC SSR primer 100개중에서 4가지 서로 다른 primer에서 선명한 band를 확인할 수 있어서 딸기의 genomic DNA내에 여러 종류의 repeat sequence가 있는 것으로 판단되었다. 따라서 각 품종별 표지로서 이용성을 알아보고자 PCR을 수행하였는 바 (ACC)_(6)와 (CCG)_(6)의 primer에서는 다른 band에 비해 매우 확실한 밴드를 형성하였다 이러한 PCR product의 염기서열분석을 위해 우선 대량증식을 위한 PCR의 적정 조건은 primer 10p㏖, DNA 50ng으로서 수행하는 것이 DNA의 증폭에 좋았다. 증폭된 1 Kb DNA 절편을 이용하여 염기서열을 조사하였던 바, 808bp의 서열을 알아냈고 그 반복염기서열은 효모와 사람에 존재하는 유전자이었으며 Cdontella sinensis와의 유의성 검정결과 ACC 반복염기에 62% 동일성을 나타내었다. This study was carried out to investigate genetic variation caused by environmental change or cultural method difference, which was performed by amplifying repeat sequence loci of strawberry widely dispersed in eukaryotic cell. DIG labeled(GGC)_(6), probe was used to test if GGC repeat sequence exists in strawberry genomic DNA, resulting in clear spot on the filter. Among the 100 UBC SSR primers which contain repeat sequence, four different primers amplified clear DNA fragments, suggesting that the repeat sequence exist in the genome of strawberry. PCR was also performed to test whether these primers could be used for a marker among strawberry cultivars. (ACC)_(6), (No. 861) and (CCG)_(6) (No. 865) primers showed very clear bands compared to the other primers. The amplified 808 bp of 1 kb DNA was sequenced, and database search using the sequence information showed that the repeat sequence was the gene existed both in yeast and human, and a significant sequence homology to Odontella sinensis was found.

Life-threatening Hemorrhage Caused by Mandibular Arteriovenous Malformation: A Case Report

( Dong Wook Kim ),( In Suk Sol ),( Min Jung Kim ),( Soo Yeon Kim ),( Jong Deok Kim ),( Bong Seok Choi ),( Yoon Hee Kim ),( Dong Joon Kim ),( Byung Moon Kim ),( Seo Yeon Jung ),( Woong Nam ),( Kyung Wo 대한응급의학회 2018 대한응급의학회지 Vol.29 No.1

Arteriovenous malformation (AVM) of the mandible is a rare vascular condition that can manifest as a wide range of symptoms and, on rare occasions, cause fatal hemorrhage. The symptoms of mandibular AVM can range from soft tissue swelling and tooth mobility to severe hemorrhage. The recognition of early symptoms is crucial for the prevention of a fatal hemorrhage and for the proper diagnosis and treatment of mandibular AVM. For emergency hemostasis of a ruptured mandibular AVM, manual compression with gauze, topical thrombin, absorbable hemostat, suturing the lesion, and replanting the extracted tooth is recommended. Multiple treatment options for mandibular AVM are available, such as arterial embolization, venous embolization, direct surgical closure, and bone resection. A combination of treatment options should be considered in complicated cases. We report a case of a 10-year-old girl with a previous history of telangiectasia on the right cheek presented with cardiac arrest resulting from massive bleeding immediately after a tooth extraction.

Impact of Time Interval between Trauma Onset and Burr Hole Surgery on Recurrence of Late Subacute or Chronic Subdural Hematoma

Kim, Dae-in,Kim, Jae-hoon,Kang, Hee-in,Moon, Byung-gwan,Kim, Joo-seung,Kim, Deok-ryeong The Korean Neurosurgical Society 2016 Journal of Korean neurosurgical society Vol.59 No.5

Objective : Although subdural hematoma (SDH) is commonly treatable by burr hole surgery in the late subacute or chronic stage, there is no clear consensus regarding appropriate management and exact predictive factors for postoperative recurrence also remain unclear. The aim of this study was to evaluate risk factors associated with recurrence of SDH that requires burr hole surgery in the late subacute or chronic stage. We also identified the appropriate timing of surgery for reducing the recurrence. Methods : We retrospectively reviewed 274 patients with SDH in the late subacute or chronic stage treated with burr hole surgery in our hospital between January 2007 and December 2014. Excluding patients with acute intracranial complications or unknown time of trauma onset left 216 patients included in the study. Results : Of 216 patients with SDH in the late subacute or chronic stage, recurrence was observed in 36 patients (16.7%). The timing of the operation in patients with late subacute stage (15-28 days) resulted in a significant decrease in recurrence (RR, 0.33; 95% CI, 0.17-0.65; p=0.001) compared to chronic stage (>28 days). Otherwise, no significant risk factors were associated with recurrences including comorbidities and surgical details. Conclusion : The results indicated that time from trauma onset to burr hole surgery may be important for decreasing the risk of recurrence. Therefore, unless patients can be treated conservatively without surgery, prompt surgical management is recommended in patients diagnosed as having late subacute or chronic subdural hematoma treatable by burr hole surgery, even when neurological deficits are unclear.

Alpha-Pinene Exhibits Anti-Inflammatory Activity Through the Suppression of MAPKs and the NF-κB Pathway in Mouse Peritoneal Macrophages.

Kim, Dae-Seung,Lee, Hyun-Ja,Jeon, Yong-Deok,Han, Yo-Han,Kee, Ji-Ye,Kim, Hyun-Jeong,Shin, Hyun-Ji,Kang, JongWook,Lee, Beom Su,Kim, Sung-Hoon,Kim, Su-Jin,Park, Sang-Hyun,Choi, Byung-Min,Park, Sung-Joo,U Institute for Advanced Research in Asian Science a 2015 The American journal of Chinese medicine Vol.43 No.4

<P>In this study, we found that alpha-pinene (α-pinene) exhibits anti-inflammatory activity through the suppression of mitogen-activated protein kinases (MAPKs) and the nuclear factor-kappa B (NF-κB) pathway in mouse peritoneal macrophages. α-Pinene is found in the oils of many coniferous trees and rosemary. We investigated the inhibitory effects of α-Pinene on inflammatory responses induced by lipopolysaccharide (LPS) using mouse peritoneal macrophages. α-Pinene significantly decreased the LPS-induced production of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and nitric oxide (NO). α-Pinene also inhibited inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expressions in LPS-stimulated macrophages. Additionally, the activations of MAPKs and NF-κB were attenuated by means of α-pinene treatment. These results indicate that α-pinene has an anti-inflammatory effect and that it is a potential candidate as a new drug to treat various inflammatory diseases.</P>

최근 국내 유입 Vibrio cholerae균 및 1995년도 국내 집단 발생 콜레라의 역학적 양상

김호훈,신영학,강연호,유천권,박미선,김동술,유재연,전정훈,이복권,박기덕,김동진,정태화,이종구,박기동,김상순,이동모,김문식,조병륜 대한감염학회 1996 감염 Vol.28 No.6

목적 : 1992년 이후 국내에 유입, 확인되는 V. cholerae 균은 현격한 증가 추세를 보이고 있으며, 1995년도 국내 집단 발생 콜레라의 역학적 양상이 종래의 경우와 상이한 바 있어 최근의 콜레라균 유입상황과 국내 역학적 특성을 정리하여 향후의 방역 대책에 참고로 하기 위하여 본 연구를 시행하였다. 방법 : 국내 유입 V. cholerae 균은 세균학적 방법에 의해 1986-1995년 사이에 확인된 균주를 대상으로 분석하였고, 국내 집단발생 콜레라는 1995년도에 내국인 거주자에게서 진성 콜레라 환자로 구명된 환자를 대상으로 역학적 양상을 살펴보았다. 결과 : 국내 유입 V. cholerae균은 1992년 이후 1995년 사이에 계절과 무관하게 뚜렷한 증가 추세를 보였다. 1995년도 콜레라 국내 집단 발생의 역학적 양상은 초발 환자가 인지되면서 단기간 사이에 지역적 연고가 없는 다양한 지역에서 콜레라 환자 발생이 확인되었다. 환자 발생 지역 내에서는 비교적 소규모 환자 발생에 그쳤고 진성 콜레라 환자로 확인된 환자 중 사망자는 없었으며 남성에서 여성보다 발병율이 높았다. 결론 : V.cholerae O1균의 국내 유입이 최근 현격히 증가되었고, 1994년에는 V. cholerae O139균의 국내유입이 처음으로 확인되었다. 콜레라 환자의 국내 집단 발생 위험은 1992년 이후 증가되었으며 1995년도의 집단 환자 발생은 지역적 연고가 없는 다양한 지역에서 비교적 단기간에 사망자 없이 소규모의 환자 발생양상을 보였다. Background: Imported Vibrio cholerae strains have increasingly been found since 1992 and the pattern of recent cholera epidemic outbreak in Korea showed a little difference from that of former epidemic outbreak. Methods: We had collected suspected V. cholerae isolates from Quarantine Stations or Public Health Laboratories, which were identified as V. cholerae O1 or O139. Epide miological analysis was made on the base of field surveys. Results: During the period from 1986 through 1995, 138 V. cholerae strains were imported. Nearly 85.5% of the strains (118 strains) were imported within recent 4 years from 1992 to 1995. One hundred and twenty-eight strains were E1 Tor-Ogawa type V. cholerae O1, 6 strains were V. cholerae O139 and 4 strains were E1 Tor-Inaba type V. cholerae O1. Of 138 strains, 71 strains were isolated from the airplane toilet swab and 67 strains from the passengers who entered into Korea after international travel. From 1993 to 1995, 101 strains were imported from the Southeast Asian countries; including Thailand(65), Indonesia(17), Philippines(10), Hongkong(6) Singapore(2) and Vietnam(1). During the cholera epidemic in 1995, 68 patients with V. cholerae O1 (E1 Tor-Ogawa) were found. Oneset of the index-case occurred on August 26th and the last on September 13th. Geographically it occurred in Incheon city(25), Chungcheongnam do(25), Kangwon do(6), Kyungsangbuck do(5), Kyunggi do(4), Daejeon city(2) and Pusan city(1). Of total 68 cases, 39 were male. Cases were found in all age groups, but it was more common in elderly groups. During the epidemic, E1 Tor-Ogawa type V. cholerae O1 strains were also isolated from the coastal sea water of Kanghwa kun where the epidemic outbreak occurred. Conclusions: In Korea, the imported V. cholerae O1 and V. cholerae O139 strains have increasingly been found without seasonal variation since 1992. Cholera epidemic outbreak in 1995, occurred simultaneously at many different local areas within a short period without mortality.