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장애유아 통합교육의 효과에 관한 고찰 : 사례분석을 중심으로
具本權 강남대학교 1999 (강남대학교)논문집 Vol.34 No.1
지난 30여년간 특수교육을 요구하는 아동교육이 발전되고 있으나 장애유아에 대한 취학전 교육은 아직도 충분한 보장을 하지 못하고 있다. 20년 전 까지 만해도 어린 장애유아의 부모들은 자녀가 조기에 치료와 교육을 받으면 많은 효과를 얻을 수 있다는 사시를 모르고 있었다. 불행하게, 특수교육교사, 의사, 발달심리학자, 아동복지사들 조차도 치료 교육에 대한 인식이 낮았다. 부모들이 장애유아의 상담을 요청하면 장차 예후가 있는지 없는지 잘 모르고, 유아가 장애로 확인되면 곧 복지 시설에 수용할 것을 권고했다. 전무가들이 장애 유아를 집에서 잘 먹이고 보호하는 것이 자녀를 위하여 최상의 대책이라고 생각하였다. 대부분의 부모들은 전문가들의 권유를 전적으로 받아드렸다. 그러나 1980년대에 전문가들은 장애아동을 시설에 수용하여 치료나 교육하는 것을 우려하기 시작했다. 장애아동 시설이 불리한 환경이기 때문이다. 국가의 경제 규모가 늘어나고 가정의 교육 향상으로 장애유아를 가정에서 보호하기 시작하고, 그들에게 교육은 특수학교보다는 일반 학교에서 교육하기를 원했다. 장애아동이 잘 계획된 일반학교에서 공부하면 이익을 얻을 수 있다는 이해가 증가했기 때문이다.
금형의 자동 계측시스템을 위한 측정 모듈설계 및 시뮬레이션 소프트웨어 개발
김옥삼,구본권 한국공작기계학회 2001 한국생산제조학회지 Vol.10 No.5
On-machine automatic measuring system of Numerically control(NC) machines permit computer control of basic material cutting processes of moulds. A part of mould designed within a CAD/CAM system can be manufactured by generation of tool paths by the measuring systems. Since the three-dimensional geometry by AutoCAD of the part is contained in the data base, the manufacturing specialist, combined with the appropriate software simulation, can not only create the commands to drive the virtual measuring and standardization of measuring modules but also can check for mistakes by viewing the computer graphics simulation of the tool cutting sequence.
관상동맥 질환에서 CD14 유전자형에 따른 세균 및 Heat Shock Protein에 대한 반응의 차이
한주용,최수연,조현주,김화평,강현재,구본권,김남중,김효수,손대원,오병희,박영배,최윤식 대한감염학회 2007 감염과 화학요법 Vol.39 No.1
Background : CD14 is the receptor for lipopolysaccharides and heat shock protein (HSP), which has been suggested being associated with increased risk of coronary artery disease (CAD). We investigated whether the response to infectious agents or HSP is different according to CD14 polymorphism in Koreans. Materials and Methods : Antibody titers to Helicobacter pylori, Chlamydia pneumoniae, and human HSP60 (hHSP60) were measured in 48 patients with stable CAD and in 41 healthy controls by ELISA. CD14 genotype was determined by PCR and high-sensitivity C-reactive protein (hs-CRP) was measured. Results : Seropositivity to C. pneumoniae and H. pylori, and antibody titer to hHSP60 were not significantly associated with the presence of CAD. CD14 genotype distribution was 31 TT (35%), 43 CT (48%), and 15 CC (17%). To compare the response to the infectious organism and hHSP60, we divided study population into 3 groups; CAD patients with non-TT genotype (group I, n=30), CAD patients with TT genotype (group II, n=18), and normal controls (group III, n=41). Seropositivity to C. pneumoniae and H. pylori, and antibody titer to hHSP60 were not significantly different among 3 groups. Though hs-CRP level was significantly different among 3 groups, post-Hoc analysis showed that hs-CRP level was not significantly different between group I and group II (group I: 1.6[1.1-3.5] mg/L and group II: 0.35[0.1-2.0] mg/L). Conclusions : This study suggests that the inflammatory responses to infectious organisms and HSP do not differ according to the CD14 genotype in Koreans. 목적 : 만성적인 세균 감염이나 자가 면역 반응이 동맥경화와 연관되어 있다는 주장이 제기되어 왔다. CD14은 lipopolysaccharides (LPS)와 heat shock protein(HSP)의 수용체로 C(-260)→T 다형성이 관상동맥 질환의 위험과 관련되어 있다고 제안되어 왔다. 본 연구에서는 한국인에서 CD14 다형성에 따른 LPS와 HSP에 대한 반응성을 염증표지자를 측정하여 살펴보고자 하였다. 재료 및 방법 : 안정형 관상동맥 환자 48명과 정상 대조군 41명을 대상으로 Chlamydia pneumoniae, Helicobacter pylori 항체 및 인체 HSP60 (hHSP60) 항체 역가를 enzyme-linked immunosorbent assay (ELISA) 방법으로 측정하였다. CD14 유전자형은 중합효소연쇄반응을 이용하여 결정하였고 hs-CRP를 측정하였다. 결과 : C. pneumonias 및 H. pylori 항체 양성 여부 및 항체 역가, 그리고 hHSP60에 대한 항체 역가는 안정형 관상동맥 질환의 유무와 유의한 상관관계는 없었다. CD14 유전자형의 분포는 TT 30명(39%), CT 31명(40%), 그리고 CC 16명(21%)이었다. 관상동맥 질환 군에서 TT 유전자형은 38%, 대조군에서는 32%로 TT 유전자형과 관상동맥 질환의 유무와는 유의한 상관관계가 발견되지 않았다(P>0.05). CD14 유전자형에 따라 C. pneumonias와 H.pylori 감염 및 hHSP60에 따른 반응에 차이가 있는지 여 부를 알아보기 위해, 관상동맥 질환 군을 다시 TT 유전자형 군과 non-TT 유전자형 군으로 나누어, 전체적으로 세군에서 항체 양성률과 역가를 비교하였다(I군: CD14 TT 유전자형을 가진 안정형 관상동맥 환자, II군: CD14 TT 유전자형을 가진 안정형 관상동맥 환자, III군: 정상 대조군). 세 군에서 C. pneumonias와 H. pylori 항체 양성률 및 hHSP60 항체 역가에는 유의한 차이가 없었다. 세 군사이에 hs-CRP 값에 유의한 차이가 있었지만, post-Hoc분석에서 II군의 hs-CRP 값이 I군에 비해 유의하게 높지는 않았다(0.35 [0.1-2.0] mg/L in group II vs. 1.6 [1.1-3.5]mg/L in group I, P>0.05). 결론 : 본 연구는 한국인에서 CD14 유전자형에 따라 LPS나 HSP에 대한 반응이 유의하게 다르지 않음을 시사한다.
이상준,박진용,임태형,윤영호,권순대,남창욱,허규찬,박근용,구본식,김상표,장종억 啓明大學校 醫科大學 1997 계명의대학술지 Vol.16 No.3
저자들은 인슐린 비의존형 당뇨병 환자에서 통증성 구강내 미란 및 전신성 수포성 미란을 동반한 심상성 천포창 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Various skin conditions such as diabetic dermopathy, necrobiosis lipoidica diabeticorum, bullosis diabeticorum, granuloma annulare occur frequently in diabetes, although common lesions may be associated by chance. Pemphigus vulgaris(PV) is a blistering skin disease seen predominantly in elderly patients. This disorder is characterized by the loss of cohesion between epidermal cells with the resultant formation of intraepidermal blisters. These blisters rupture easily, leaving denuded areases that may crust and enlarge peripherally. In half or more of patients, lesions begin in the mouth: approximately 90% of patients have oromucosal involvement at some time during the course of their disease. But the relationship of this disorder with diabetes is not clear. We experienced a case of pemphigus vulgaris associated with NIDDM in 67 years old woman who was admitted due to painful oral ulcer and control of blood glucose, so we present this case with a review of literatures.
Virological and pathological characterization of an avian H1N1 influenza A virus
Koo, Bon-Sang,Kim, Hye Kwon,Song, Daesub,Na, Woonsung,Song, Min-Suk,Kwon, Jin Jung,Wong, Sook-San,Noh, Ji Yeong,Ahn, Min-Ju,Kim, Doo-Jin,Webby, Richard J,Yoon, Sun-Woo,Jeong, Dae Gwin Springer-Verlag 2018 Archives of virology Vol.163 No.5
Koo, Bon-Kwon,Waseda, Katsuhisa,Kang, Hyun-Jae,Kim, Hyo-Soo,Nam, Chang-Wook,Hur, Seung-Ho,Kim, Jung-Sun,Choi, Donghoon,Jang, Yangsoo,Hahn, Joo-Yong,Gwon, Hyeon-Cheol,Yoon, Myeong-Ho,Tahk, Seung-Jea,Ch Ovid Technologies Wolters Kluwer -American Heart A 2010 Circulation. Cardiovascular interventions Vol.3 No.2
<P>BACKGROUND: We sought to investigate the mechanism of geometric changes after main branch (MB) stent implantation and to identify the predictors of functionally significant 'jailed' side branch (SB) lesions. METHODS AND RESULTS: Seventy-seven patients with bifurcation lesions were prospectively enrolled from 8 centers. MB intravascular ultrasound was performed before and after MB stent implantation, and fractional flow reserve was measured in the jailed SB. The vessel volume index of both the proximal and distal MB was increased after stent implantation. The plaque volume index decreased in the proximal MB (9.1+/-3.0 to 8.4+/-2.4 mm(3)/mm, P=0.001), implicating plaque shift, but not in the distal MB (5.4+/-1.8 to 5.3+/-1.7 mm(3)/mm, P=0.227), implicating carina shifting to account for the change in vessel size (N=56). The mean SB fractional flow reserve was 0.71+/-0.20 (N=68) and 43% of the lesions were functionally significant. Binary logistic-regression analysis revealed that preintervention % diameter stenosis of the SB (odds ratio=1.05; 95% CI, 1.01 to 1.09) and the MB minimum lumen diameter located distal to the SB ostium (odds ratio=3.86; 95% CI, 1.03 to 14.43) were independent predictors of functionally significant SB jailing. In patients with > or =75% stenosis and Thrombolysis In Myocardial Infarction grade 3 flow in the SB, no difference in post-stent angiographic and intravascular ultrasound parameters was found between SB lesions with and without functional significance. CONCLUSIONS: Both plaque shift from the MB and carina shift contribute to the creation/aggravation of an SB ostial lesion after MB stent implantation. Anatomic evaluation does not reliably predict the functional significance of a jailed SB stenosis.</P>
Koo, Bon-Kwon,Park, Kyung-Woo,Kang, Hyun-Jae,Cho, Young-Seok,Chung, Woo-Young,Youn, Tae-Jin,Chae, In-Ho,Choi, Dong-Ju,Tahk, Seung-Jae,Oh, Byung-Hee,Park, Young-Bae,Kim, Hyo-Soo W.B. Saunders [etc.] 2008 European heart journal Vol.29 No.6
<P>This study was performed to evaluate the functional outcomes of fractional flow reserve (FFR)-guided jailed side-branch (SB) intervention strategy.</P>
구본권 ( Bon Kwon Koo ) 대구대학교 한국특수교육문제연구소 2006 특수교육저널 : 이론과 실천 Vol.7 No.2
This study investigated the personality characteristics of 342 students who majored in special education. Those 342 participants completed the MMPI (Minnesota Multiphasic Personality Inventory) from 1991 to 2004. First, the result indicated that male participants had a higher mean t-score in 10 sub-tests than female participants. In particular, male participants had significantly higher t-scores in Hysteria scales than female participants. Second, the result showed that there was an annually significant difference of t-scores in Psychasthenia and Schizophrenia. t-scores increased in Hypochondriasis, Depression, and Hysteria scales, and decreased in Paranoia, Psychasthenia, Schizophrenia, and Hypomania scales. Third, 232 participants (67.8% of 342 participants) had 70 or above in t-scores. Among those 232 participants, 49 participants (68% of 232 participants who had 70 or above in T-scores) had the highest mean t-score in 1998. The high mean t-scores in sub-tests were showed in Psychopathic Deviation, followed by in Psychasthenia and in Schizophrenia.
구본권 ( Bon Kwon Koo ) 한국유아특수교육학회 2001 유아특수교육연구 Vol.1 No.1
This study focused on investigating students in elementary school as to occurring events in integrated education of children with disabilities by having an - interview. There were more students who had an affirmative attitude than those who had a negative attitude, on integrated education of students. Students who had experienced integrated education showed more affirmative attitude than those who had not; however, significantly many students reacted to a negative attitude for questions directly relevant to themselves. In consequence, many students negatively recognized that they study along with children with disabilities. For instance, students were asked if a student with disabilities became their partner in class. They answered that they would not like it to do so because they felt inconvenience. A reason was due to the fact that students had to help the student with disabilities if they became a partner of the student with disabilities in class. But students also answered that they would not care if they were not the partner of the student with disabilities in class. These students who answered the question showed a dual attitude. In other words, students showed an affirmative reaction to questions unrelated to themselves, and on the other hand, they showed a negative reaction if the student with disabilities had a relationship with them. Other students without integration experience even showed an affirmative reaction which they would assist students with disabilities, however, it was recognized as their sympathy since students with disabilities are pitiful in their temperament.