말에서 급성장염과 관련된 페장에서의 Aspergillus감염증

윤병일,허권,김대용,박응복,하태영,서일복,Yoon, Byung-Il,Hur, Kwon,Kim, Dae-Yong,Bak, Ung-Bok,Ha, Tae-Young,Seo, Il-Bok 한국임상수의학회 1998 한국임상수의학회지 Vol.15 No.1

A 5 year-old male Throughbred horse housed in Korean Racing Association died after having enteritis and respiratory disorder for about 10 days. At necropsyi the left and right caudal lung lobes were reddenedi swolleni and contained numerous well-defined sublobular consolidated foci. The large intestine was diffusely reddened and covered with pseudomembranous exudates. Microscopicallyi multifocal areas of necrosis with mild to moderate infiltration of neutrophilsi macrophages and Iymphocytes as well as hemorrhage and edema were noted in the lung. The fungi having conidiophorei dome-shaped vesicles phialides and conidia which are characteristic of Apergillosis fumigatus was isolated from the lung. The colonic mucosa was transmurally necrotic and severe congestions edema and thrombi were observed in the submucosa. The embolic mycotic pneumonia present in this case Probably occured secondary to antibiotic therapy given for treatment of enteritis.

The Anti-Inflammatory Effects of a New Herbal Formula (WSY-1075) in a Nonbacterial Prostatitis Rat Model

윤병일,배웅진,김수진,김효신,하유신,손동완,황성연,김세웅 대한남성과학회 2013 The World Journal of Men's Health Vol.31 No.2

Purpose: The aim of this study was to investigate the anti-inflammatory effects of a new herbal formula (WSY-1075) in a nonbacterial prostatitis rat model.Materials and Methods: Prostatitis was induced in male Wistar rats (n=32) by treatment with 17 beta-estradiol and dihydrotestosterone for 4 weeks. After the induction of prostatitis, the rats were randomly divided into one of four treatment groups: control (n=8), ciprofloxacin (n=8), WSY-1075 (100 mg/kg) (n=8), and WSY-1075 (400 mg/kg) (n=8). After 4 weeks of treatment, the prostatic proinflammatory cytokine (tumor necrosis factor-α, interleukin [IL]-6, and IL-8) levels and histological findings were noted.Results: The ciprofloxacin and WSY-1075 treatment groups showed significantly decreased proinflammatory cytokine levels compared with the control group. Histologically, treatment with ciprofloxacin and WSY-1075 significantly suppressed the severity of prostatitis lesions compared with those in the control group. No differences in the proinflammatory cytokine levels or histologic findings were observed with the dose dependent treatment of WSY-1075.Conclusions: The new herbal formula, WSY-1075, showed effective anti-inflammatory activities in the prostate and may be useful for the clinical treatment of nonbacterial prostatitis. Our findings suggest that WSY-1075 has a beneficial effect on the prevention and treatment of nonbacterial prostatitis.

만성 세균성 전립선염 흰쥐 모델에서 셀레늄 함유 온천수 음용의 항염 및 항균효과

윤병일,김세웅,배웅진,하유신,홍성후,이지열,윤건호,황태곤,조용현 대한남성과학회 2012 The World Journal of Men's Health Vol.30 No.1

Purpose: The conventional primary therapy for chronic bacterial prostatitis (CBP) is the use of antibiotics. However, the therapy has a low cure rate and long-term use of antibiotics can lead to adverse effects including bacterial resistance. For these reasons, a new therapy for CBP is strongly needed. Materials and Methods: To evaluate the anti-inflammatory and antimicrobial effects of selenium-rich hot spring water on CBP, rats were divided into four groups and treatment was administered for four weeks as follows: (1) control (n=8), (2) ciprofloxacin (n=8), (3) selenium-rich hot spring water (n=8), and (4) selenium-rich hot spring water with ciprofloxacin (n=8). Drip infusion of bacterial suspension (E. coli Z17 O2:K1;H−) into Spargue-Dowley rats was then conducted to induce CBP. Four weeks later, the results of prostate tissue and urine culture and histological analysis on the prostate were analyzed in each group. Results: The use of ciprofloxacin, and selenium-rich hot spring water with ciprofloxacin showed statistically significant decreases in bacterial growth and improvements in prostatic inflammation compared with the control group (p<0.05). The selenium-rich hot spring water with ciprofloxacin group showed a statistically significantly lower rate of bacterial growth and and greater improvements in prostatic inflammation than the ciprofloxacin group (p<0.05). Conclusions: These results suggest that spring water may be an effective material in the treatment of CBP. Notably, the combination treatment of selenium-rich hot spring water and ciprofloxacin has synergistic effects. Therefore, we can suggest that the combination of selenium-rich hot spring water and ciprofloxacin may be effective in the treatment of CBP, and with a higher success rate than ciprofloxacin alone.

경기만 한강하구 수로별 조석전파 특성 분석

윤병일,우승범,김민하 대한조선학회 2011 대한조선학회 학술대회자료집 Vol.2011 No.6

난소암에서 CA125의 임상적 의의

윤병일,김수녕,손인숙,유연웅,최원석 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

The concentration of the tumor marker CA125 in serum from patients with ovarian tumor was measured to define the usefulness of them in differentiating malignant ovarian tumor from benign ovarian mass. In the study of 105 patients with gynecologic neoplasm, of whom 38 were myoma uteri, 42 benign ovarian tumor, and 25 ovarian cancer, the level of serum CA125 were measured. CA125 was greater than 35 U/ml in 2.6% of myoma uteri, in 2.4% of benign ovarian tumors and 68.0% of ovarian cancers. Using a cut-off level of 35 U/ml, the results can be characterized by a 68.0% of sensitivity and 97.5% of specificity in detecting an ovarian cancer. Among 25 patients with ovarian cancer, 11 of 14 (78.6%) patients with serous cystadenocarcinoma, 4 of 6 (66.7%) patients with mucinous cystadenocarcinoma and 2 of 5 (40.0%) patients with endometrioid carcinoma had CA125 values greater than 35 U/ml. In relation to a higher tumor stage, there was an increasing incidence of elevated levels of CA125. As a result, it is likely that the measurement of CA125 is useful for early diagnosis of ovarian cancer.

천수만 주변해역에 출현하는 부유성 어란 및 자치어의 분포특성

윤병일,최동혁,최윤석,이승환,권대현,김맹진 한국수산해양기술학회 2022 수산해양기술연구 Vol.58 No.4

To provide information needed for managing fish resources and protecting the ecosystem of Cheonsu Bay, bimonthly variations in species composition and abundance of fish eggs and larvae were investigated. The samples were collected by using bongo net at three different stations from February 2020 to December 2021. Fish eggs were divided into Engrualis japonicus and unidentified eggs, of which Engragulis japonicus accounted for 85.6% of the total eggs collected. A total of 21 species representing 17 families and 6 orders were collected. The three dominant species were Gobiidae spp, Thryssa hamiltonii and E. japonicus and these three species accounted for 74.1% in the total number of individuals. The number of species was highest in August, 2020 and lowest in February, 2020 and 2021; the number of individuals was highest in August, 2020 and lowest in February, 2020. Temporal changes in the abundances of pelagic eggs and larval fishes corresponded with temperature. 천수만 주변해역에서 위치한 3개 정점에서 2020년부터 2021년까지 격월로 연 6회에 걸쳐 부유성 어란 및 자치어를 채집하였다. 조시기간 중 수온염분변화는 표층 수온은 8월에 28.4℃로 가장 높았으며, 2월에는 4.7℃로 낮게 나타났다. 어란은 멸치가 28,211 ind./1,000 ㎥로 출현량의 85.6%로 가장 우점하였고, 자치어는 망둑어과 2,499 ind./1,000 ㎥로 출현량의 37.0%, 다음은 반지가 1,730 ind./1,000 ㎥로 출현량의 25.6%가 출현하여 우점하였다. 생태학적 지수는 다양도지수가 0.354-1.704, 균등도지수는 0.497-0.951, 우점도지수는 0.490-1.000, 풍부도지수가 0.191-1.253로 나타났으며, 자치어의 월별 유사도는 6월과 8월이 하계그룹으로 가장 유사하게 나타났다.

평수기 한강하구 염하수로 인근의 낙조 우세 및 조석 평균 흐름의 정량적 분석

윤병일,우승범 대한조선학회 2012 대한조선학회 학술대회자료집 Vol.2012 No.5

서해 5도 주변해역에서 출현하는 홍어(Okamejei kenojei)의 식성

윤병일,최동혁,이승종,이승환,한경호,김맹진 한국어류학회 2020 韓國魚類學會誌 Vol.32 No.3

The feeding habits of ocellate spot skate (Okamejei kenojei) were studied by analysis of stomach contents. Specimens of O. kenojei (n=379) were collected in the cosatal waters five west Islands of the Korea, monthly from January to December 2019. The size of O. kenojei ranged from 5.9 to 34.5 cm in disc width (DW). O. kenojei was consumed mainly macrura (77.9%) and pisces (21.9%) in % IRI. But, brachyura, stomatopoda, cephalopods, and others showed a low ratio. The macruara feeding rate was highest in summer, whereas the proportion of pisces was the higher in winter than other seasons. 2019년 1월부터 12월까지 서해5도 주변해역에서 채집된 홍어 379개체의 위내용물 조성을 조사하였다. 홍어의 체반장은 5.9~34.5 cm의 범위를 보였고, 새우류가 가장 우점한 먹이생물 분류군으로 나타났으며, 그 다음으로 어류의 비율이 높았고, 그 외 집게류, 갑각류, 두족류 등이 낮은 비율로 섭식되었다. 새우류의 비율은 하계에서 가장 낮은 비율을 보였고, 동계에서는 높았으며, 어류는 하계에서는 높았고, 동계에서는 낮게 나타났다.

한강하구 염하수로 주변에서의 조석·조류 비대칭과 창·낙조 우세 분석

윤병일,우승범,Yoon, Byung-Il,Woo, Seung-Buhm 한국수자원학회 2012 한국수자원학회논문집 Vol.45 No.9

한강하구 염하수로 주변의 조석 조류 변형과 창 낙조 우세를 분석하기 위해서 4개 정점에서 동기간에 관측한 조류자료와 기 관측된 조석자료를 분석하였다. 조석 및 조류의 변형 정도는 $M_4/M_2$ 진폭비를 분석한 결과 상류로 갈수록 증가하며, 조석의 상대 위상차($2M_2-M_4$)를 계산하면 모든 정점의 값이 $180^{\circ}C$ 이하로 창조 우세를 보여준다. 그러나 조류자료의 통계분석 결과를 보면 조석 조화상수의 상대 위상차 결과와는 다르게 최강 평균 낙조가 창조에 비하여 강하게 나타나며, 정조시각을 이용하여 창조, 낙조 지속시간을 계산하면 낙조 지속시간이 길게 나타난다. 각 조류 관측정점의 주축 방향 유속성분의 상관도를 분석한 결과 인천항 이후 염하수로 북쪽입구까지는 상관도 값이 0.9 이상으로 높게 나타났다. 조류 분석결과에서 보여지는 낙조가 우세하고 낙조 지속시간이 긴 형태의 원인을 분석하기 위해서 조화분해 결과를 재구성하였다. 주 분조($M_2$)와 천해 분조($M_4$)를 결합하면 창조가 우세하고 낙조 지속시간이 긴 전형적인 창조우세 형태의 곡선이 나타난다. 그러나 이 곡선에 조류 성분의 산술 합으로 계산한 비 조류성분(잔차류)의 값을 더하면 낙조가 강해지고 낙조 지속시간이 긴 형태로 나타난다. 즉, 천해분조에 의해서 발생하는 상류방향의 흐름을 극복하는 담수와 하구 비선형 효과에 의해서 생성되는 장주기 조류성분과 같은 낙조방향의 평균적인 흐름이 존재하기 때문에 독특한 낙조심화 현상이 염하수로에서 나타난다. Han River estuary (HRE) is located at the middle of the western coast of Korea, and tidal currents were measured at 4 stations in this estuary during the winter season, and previously observed tide data was analyzed. The results of amplitude ratio of $M_4/M_2$ showed that increasing upward to estuary in the HRE. Tide harmonic constants of relative phase $2M_2-M_4$ represent flood dominance, with under 180 degree. But this method has a limit of analysis that typically based on the non-linear distortion of the tidal current in tidal lagoon system where freshwater discharge is assumed to be relatively small. The results of statistically tidal current data indicated that ebb current velocity would be great unlike tide data. Ebb and flood duration time is calculated by slack time of tidal current showed that ebb duration time is longer than flood. The results of correlation of analysis show high value (0.9) between tidal current stations from Incheon harbor to north entrance of Yeomha channel. We reconstructed to find the reasons for the features of ebb dominance the results of harmonic analysis. As major component ($M_2$) in combination with shallow water component ($M_4$), the tidal curve was presented flood dominance that has a flood current is stronger. However, these curve were changed to ebb dominance add up the non-harmonic components that had ebb direction flow by calculated tidally averaged current. The characteristic of enhancement on ebb is showed around the Yeomha channel in the HRE, because averaged flow which acts seaward such as long-term tidal current components due to non-linear effect and freshwater which overcome the flood current.

복강경하 질식 자궁적출술 30예의 임상적 고찰 : A Review of 30 Cases

윤병일,김소정,정두용,김수녕,손인숙,이지영 건국대학교 의과학연구소 2003 건국의과학학술지 Vol.13 No.-

Hysterectomy is the most common gynecologic operation. Traditionally, hysterectomy was performed either through an abdominal approach or through a vaginal approach. Recently, laparoscopic hysterectomy is quite often tried. To evaluate the effectiveness and value of LA VH(Laparoscopy Assisted Vaginal Hysterectomy), and to evaluate the possibility whether to rep;ace abdominal hysterectomy to LAVH, we analyzed our clinical cases. This clinical study is a retrospective review of 30 cases of LAVH from May 2002 to February 2003 at the department of Obstetrics and Gynecology, Chung- Ju hospital, Konkuk University. We evaluated age, parity, previous abdominal operations, indications of hysterectomy, combined operation, operating time, hemoglobin change, weight of uterus, hospital stay and postoperativeThe average operating time was 146 ± 42 minutes, the uterine weight was 239 ± 126 grams, and the mean postoperative hemoglobin loss was 1.7 ± 1.4 g/dl. The most common pathologic finding was myoma uteri(37%), and the second most pathologic finding was adenomyosis(20%) and myoma uteri with adenomyosis (20%). Serious complications were not appeared. LAVH provides a shorter hospital stay, quicker recovery, and the acceptable complication rate except incerased operating time than abdominal hysterectomy. This study suggests that LAVH appears more useful than TAH(Total Abdominal Hysterectomy) and could replace abdominal hysterectomy.