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Visceral Lymphosarcoma in a Dog
박응복,성재기,이창우,김정환,Bak, Ung-bok,Sung, Jai-ki,Lee, Chang-woo,Kim, Jung-whan The Korean Society of Veterinary Science 1985 大韓獸醫學會誌 Vol.25 No.2
3주간에 걸쳐 심한 수척, 혈뇨, 질루, 구토중상과 경부종류(頸部腫瘤)가 촉진된 18개월령 암컷의 Great Dane개가 임상적으로 검사되고 사후에 부검되었다. 경부종류(頸部腫瘤)의 주사침 생검에서 관찰한 세포소견에서 종양세포가 대식구 유래임을 짐작하였고 종양조직 표본에서도 주요 구성세포는 조직구의 특성을 나타내고 있었다. 육안적으로는 임파절, 편도선 및 비장에서 큰 결정상의 종양괴를 확인하였다. 이상과 같은 종양의 생검 및 조직소견과 육안소견의 특징에서 본 종양예는 다중심성으로 발생한 조직구성 임파육종(淋巴肉腫)으로 진단되었다. An eighteen months old, female, Great Dane dog which had shown signs of severe cachexia, dehydration, hematuria, vomiting and the palpable cervical mass during three weeks was examined clinically and necropsied after death. Diagnosis of this tumor case was made by gross pathology, cytology of the aspirate, radiography of the abdomen and the tumor tissse as multicentric, histiocytic lymphosarcoma. Cytologic findings of the needle aspirate of the cervical lesion were typical of macrophage origin cell. The tnmor was encountered predominantly in the lymph nodes, tonsils and spleen. The predominant cell type of these tumor masses manifested characteristics of histiocytic cells.
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박응복 진주농과대학 1964 진주농과대학 연구논문집 Vol.- No.3
Mass-examination into a herd of calves accompaning with severe anemia and emaciation in an endimic area(Chinju diteict) of cattle hookworm was held from hematological and pathological aspects. In this case, by fecal examination every calfe of the herd (20 calves) was revealed the infection with hookworms, among them 5 calves were dead of extreme inantion. Results obtained from these investigations were summerized as follows. Identification of the parasite: In the hejnum and numerous small round worms occured, for example; 546 in case 2,783 in case 3. The male was 12∼18mm, and female 9∼26mm. long. In the buccal capsule bore three pairs of lancets. The male spicules were slender and 3.8∼4.1mm long. The eggs measured about 92.3∼98.8 by 48.2∼50.16μ. (Fig. 4,5,6,7.) O1 above morphological findings these worms were identified with Bunostomum phlebotomum Railliet(1990). Hamatological findings; (1) The blood was very thin in color and the numbers of eruthrocyter were than 1.92 million per cmm. blood, in case 3 it accounted as 0.98 million. (Fig 1) (2) On measuring of the erythrocytes diameter the ranges of variation was very wide, 3.2∼9.1μ and so marked anisocytosis was recognized. In Price-Jones curve is peaks shifed to left side. (Fig. 2,8) (3) The amount of hemoglobin in the blood was much reduced under 6gm/100ml, in case 3 the measurement through Sahli's apparatus was immposible. (Fig 1) (4) The leukccyte count was generally within the normal and without significant in the differential count except eosinophiles which was increased fairly. (Fig. 1,3.) Painological findings; (1) Most visceral organs were showing grossly edematous swelling and anemia espicially in the abomasum, intestines and skeletal muscles. (2) The mucoid degeneration occured in every adipose connective tissue around the viscera ot under the skin of jaw and neck. (3) In the mucosa of the small intestine hemorrhagic catarrh was shown and in the Brunner's gland its proli feration was prevalent (Fig. 9, 10, 11) (4) In the spleen there were a marked accumulation of phagocytized hemosiderins and erythrocytes. n(Fig. 15) (5) The lesions consist of wide areas of skeletal muscle which were whitish in color and which were found microscopically to be progressing hyaline degeneration with swelling fragmentation and disappgrarence of many muscle fibers. (Fig. 14)
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An Outbreak of Ibaraki Disease in Korea
박응복,정창국,최희인,이창우,오효성,이영옥,조명래,임영일,Bak, Ung-Bok,Cheong, Chang-Kook,Choi, Hee-In,Lee, Chang-Woo,Oh, Hyo-Sung,Rhee, Young-Ok,Cho, Myung-Rae,Lim, Young-Il The Korean Society of Veterinary Science 1983 大韓獸醫學會誌 Vol.23 No.1
Epizootics and sporadic outbreaks of the cattle disease characterized by fever, stomatitis and dysphagia were observed in Korea in September through November, 1982. The number of cattle showed typical symptoms of the disease was estimated to 73 and these animals were concentrated in Gyongido province, the central district of Korea. In other districts around Gyongido province the disease tended to be sporadic occurrence. The main lesions of the disease were defined as edema, hemorrhage, degeneration and necrosis of the oral mucosa and musculatures of the esophagus and laryngopharyngeal area, and abomasum. Of these lesions hyaline degeneration and hemorrhage of the striated muscle of the esophagus and laryngopharyngeal area were the most striking changes of the disease and rated to be the lesion of diagnostic significance. The serum samples of the cattle with typical symptoms showed significant positive titer of the antibodies against Ibaraki virus. On these clinical, epidemiological, pathological and serological findings of the disease it was diagnosed as Ibaraki disease presenting the only report on the epizootics in the countries other than Japan. 1982년 9월부터 11월까지 사이에 경기도(京畿道) 일원의 소에서 발열(發熱), 구내염(口內炎), 연하장애(嚥下障碍)를 나타내는 질병(疾病)이 유행성(流行性)으로 발생하였다. 이와같은 질병(疾病)은 같은시기에 충청남도(忠淸南道), 강원도(江源道), 전라남도(全羅南道) 및 경상남도(慶尙南道)의 일부지역에서도 산발적으로 발생하였고, 특징적인 임상소견(臨床所見)으로서 확인된 발생두수(發生頭數)는 73두에 달하였다. 이 질병(疾病)에서 관찰된 주요 병변(病變)은 구강점막(口腔粘膜), 인후두(咽喉頭), 식도(食道) 및 사위(四胃)의 수종(水腫), 출혈(出血), 변성(變性) 및 괴사(壞死)이었으며 이들 병변(病變)중에서도 식도(食道)와 인후두근육(咽喉頭筋肉)의 초자양변성(硝子樣變性)과 출혈(出血)은 진단적(診斷的)인 소견(所見)으로 간주되었다. 특징적인 임상소견(臨床所見)을 보인 소에서 채취한 혈청(血淸)에서 Ibaraki바이러스에 대한 중화항체(中和抗體)가 증명되었다. 이상과 같은 임상(臨床), 역학적(疫學的), 병리학적(病理學的) 및 혈청학적(血淸學的) 소견(所見)에 의하여 질병(疾病)은 Idaraki병(病)이라고 진단(診斷)되었으며 일본(日本) 이외지역의 발생보고는 처음인 것이다.
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박응복,김대춘,김태현,예재길,Bak Ung-Bok,Kim Dae-Choon,Kim Tae-Hyon,Ye Jae-Gil 한국임상수의학회 1984 한국임상수의학회지 Vol.1 No.1
Among the 308 breeding pigs imported via airway from Canada, 15 pigs died from the respiratory disease. Three of the carcases were examined by pathological and bacteriological means. In the lungs of the necropsied cases there was a lobar pleuropneumonia characterized by parenchymal hepatization, carnification and extensive adhesion between the thoracic organs due to fibrinous pleural thickening. Histologically the affected lungs had lesions of thrombosis and coalesced area of necrosis delineated by packed macrophages. A strain of Haemophilus Pleuropneumoniae was isolated from the affected lungs. The isolate was serologically identified as serotype 5.
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