효과적인 지식공유를 위한 질적 연구지역 기업들의 업무인수인계 상황을 중심으로 -

문효성,구은영,정무관 경남대학교 산업경영연구소 2020 지역산업연구 Vol.43 No.3

This study focuses on the work transition, which is the most frequently occurring knowledgesharing situation in companies, and attempts to find the successful work transition. To attain theresearch purpose, a qualitative research was carried out through an interview of the officials involvingwork transition, eliminating subjective factors at maximum, with the focus on the situation of worktransition happening in the four places, manufacturer, financer and semi-public agency. The results ofthe qualitative analysis of the interview reveal that important variables to be considered in thesituation of work transition are classified into the three: relational, vocational and organizationalfactors. First, regarding the relational factors, it is revealed that establishing trust and ties betweenofficials involving work transition is important. It is considered that establishing such relations ismore highly effective when smooth communication is made. Also it is found that similar workposition or similar age range bring about smooth ties. Second regarding the vocational factors,smooth work transition can be made through interdependence. As for work procedure, it was foundthat a highly similar tendency causes a quick understanding about work. In the case otherwise, itwas shown that just conveying explicit knowledge becomes the entire focus of attention. Lastlyregarding organizational factors, it was found that each conglomerate undergoes the work transition,based on corresponding procedures and manuals. As mentioned foregoing, most conglomeratesremained just conveying explicit knowledge. But it was found that small organizations make smoothrelational factors, which leads to a smoother procedure of work transition. 본 연구는 기업에서 가장 빈번하게 발생되는 지식공유 상황인 업무의 인수인계에 초점을 두고, 성공적인 업무 인수인계 방안을 찾고자 하였다. 본 연구의 목적을 달성하고자 제조업, 금융업, 준공공기관 등 4개 조직의 업무인수인계 상황에 초점을 두고, 인수인계 당사자들을 대상으로 최대한 주관적인 요인을 배제하고 인터뷰를 통한 질적 연구를 실시하였다. 특히 업무인수 인계 후의 성과에 대한 객관적인 평가를 위하여 상사 및 관계자에 대한 인터뷰도 실시하였다. 인터뷰들을 대상으로 질적 분석을 실시한 결과, 업무인수인계 상황에서 중요하게 고려해야 될 변수들은 크게 관계적 요인과 직무 요인, 조직 요인의 세 가지로 분류되었다. 먼저, 관계적 요인에서인수인계 대상자 간의 신뢰와 유대감 형성이 중요한 것으로 나타났으며, 이러한 관계형성은 의사소통이 원활할수록 더 효과가 높은 것으로 판단되었다. 그리고 인수인계 당사자 간의 직급이나 연령대가 비슷할수록 유대관계 형성이 원활하다는 것도 발견할 수 있었다. 두 번째, 직무 요인 측면에서 보면, 유기적인 상호작용이 필요한 직무의 인수인계에서 대상자들 간 보다 원활한지식공유가 이루어졌다. 또한 인수 전 업무와 인수 후 업무간의 유사성이 높을수록 업무에 대한이해도가 빨랐지만, 반대인 경우에는 형식지의 전달에만 급급한 모습을 보였다. 마지막으로, 조직 요인의 측면에서 보면, 각 기업들 마다 업무인수인계에 대한 절차와 매뉴얼을 가지고 시행하고 있었지만, 주로 형식지의 전달에 머무는 경우가 많았다. 다만, 소규모 조직일수록 관계적인요인 형성이 원활하여 업무인수인계가 더 원활한 것으로 파악되었다.

레이저절제술을 받은 조기성문암 환자의 음성평가

문효성,최소희,이형신,홍종철,한영진,김경아,이강대 대한이비인후과학회 2008 대한이비인후과학회지 두경부외과학 Vol.51 No.3

Voice quality may be an important issue for choosing treatment options of early glottic cancer. It has been reported that voice quality is worse after laser cordectomy compared to that of radiation therapy. But, with developed visualization tools, the precise localization of lesions became possible enabling surgeons to decide the appropriate surgical extent to preserve voice after laser cordectomy. The authors assessed the postoperative voice quality of patients who underwent laser cordectomy according to the classification by the European Laryngological Society. Subjects and Method:Thirty patients who were diagnosed with glottic cancer and treated with laser cordectomy between April, 1999 and January, 2006, were evaluated. All the patients were followed-up more than 6 months. Objective evaluations included maximal phonation time, fundamental frequency, jitter, shimmer, noise-to-harmonics ratio and subjective evaluation was performed by the GRBAS scale. Results:The type II laser cordectomy group and some cases of the type III cordectomy showed no significant differences compared with the normal control group in both objective and subjective evaluations. Conclusion:This study shows that the group of laser cordectomy type II and some cases of type III had acceptable results compared to that of the normal control group. Thus, laser cordectomy could be considered as an alternative to radiation therapy in selected patients with early glottic cancer, even when preserving the quality of voice is an important issue. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:250-5)

인후두 증상 및 후두경 소견으로 인후두 역류를 예측할 수 있는가?

문원 ( Won Moon ),박무인 ( Moo In Park ),김경미 ( Gyung Mi Kim ),김규종 ( Kyu Jong Kim ),박선자 ( Seun Ja Park ),문효성 ( Hyo Sung Mun ),이강대 ( Kang Dae Lee ),김윤정 ( Yoon Jung Kim ),임대관 ( Dae Kwan Lim ),노지훈 ( Ji Hun Roh 대한소화기기능성질환·운동학회 2007 Journal of Neurogastroenterology and Motility (JNM Vol.13 No.1

목적 : 인후두 역류는 아직 잘 이해되지 않고 있으며 아시아인에서 더욱 그렇다. 이에 본 연구자 등은 한국인에서 인후두 역류의 심한 정도와 증상 및 증후들 사이의 관계성에 대해 평가하고자 하였다. 대상 및 방법 : 비흡연자로서 후두 증상을 갖고 reflux symptom index (RSI)로 구성된 증상설문지, 후두경검사를 통한 reflux finding score (RFS), 식도내시경, 식도내압검사 및 24시간 인두 pH 검사를 모두 마친 환자들의 자료를 후향적으로 분석하였다. 결과 : 대상자 52명은 1회 이상의 인후두 역류가 있는 역류 양성군 25명과 27명의 역류 음성군으로 나뉘었다. 양군 모두에서 가장 두드러진 증상은 목소리가 자주 쉬거나 목소리를 내는데 어려움을 느낀다였고 후두경적 소견은 후연합 비대였다. RSI (11점 vs. 14점), RFS (4.8점 vs. 4.9점), 역류성 식도염의 빈도, 식도 괄약근 기저압, 식도연동운동의 양상 모두에서 양군간의 차이가 없었다. 역류 양성군에서 역류횟수의 평균은 9.0회였고 %시간은 1.2%시간이었다. 역류의 심한 정도가 증상 및 증후와 상관성은 없었으나 하부식도 괄약근압과는 역상관 관계가 있었다. 결론 : 한국인에서 인후두 증상 및 후두경 소견은 인후두 역류 유무를 예측할 수 없다. Background/Aims: The pathophysiology of laryngopharyngeal reflux (LPR) is not completely understood yet, especially in Asian people. The aim of this study was to evaluate the relationship between reflux severity and laryngeal symptoms and signs in Koreans. Methods: Non-smoking patients with laryngeal symptoms, who completed reflux symptom index (RSI) questionnaire, laryngoscopic reflux finding score (RFS), esophagoscopy, esophageal manometry and 24-hour pharyngeal pH testing were evaluated retrospectively. Results: Fifty-two patients were enrolled. Twenty-five patients had one or more reflux episodes and were classified as a reflux group (RG) and the remaining twenty-seven as a non-reflux group (NRG). The most predominant symptom was voice problem and predominant sign was posterior commissure hypertrophy in both groups. There was no difference in total scores of RSI (11 vs. 14) and RFS (4.8 vs. 4.9), the rate of reflux esophagitis, the basal pressures of upper and lower esophageal sphincters (PUES and PLES) and the rate of normal peristalsis between RG and NRG. In the RG, the mean number and the %time of pharyngeal acid reflux were 9.0 and 1.2% and none of symptoms and signs were correlated with reflux severity but the reflux number were correlated inversely with PLES. Conclusions: Laryngeal symptoms and laryngoscopic findings did not seem to predict LPR in Korean patients. (Kor J Neurogastroenterol Motil 2007;13:8-14)

Vista Hall : The Relationship between Laryngopharyngeal Reflux and Symptoms and Signs

문원,박무인,김경미,서정훈,김규종,박선자,문효성,이강대 대한소화기학회 2006 대한소화기학회 추계학술대회 Vol.2006 No.-

가족성 갑상선 수질암에 대한 RET 유전자의 점돌연변이 분석

이강대,문효성,김주연,정헌,최소희,하남욱,Shinya Uchino 대한이비인후과학회 2004 대한이비인후과학회지 두경부외과학 Vol.47 No.9

Background and Objectives:Hereditary medullary thyroid carcinoma is presented as a part of MEN2A (65- 75% ) or MEN2B, but can also be inherited alone, which is called familial medullary thyroid carcinoma. The author sought to detect point mutations of the RET proto-oncogene using the molecular genetic method on the family line of the familial medulary thyroid carcinoma, which is identified by the family history of an index patient, and to investigate the presence of point mutation cariers among the Subjects and Method:DNA was extracted from the peripheral blod leukocyte of 5 patients who were asumed to have sporadic medulary thyroid carcinoma and 1 patient who was an index of a family line asumed to contain hereditary medullary thyroid carcinoma according to the family history. The PCR amplification of exons, 10, 11, 13, 14, 15, 16 was then caried out, and we investigated point mutations of the RET proto-oncogene using a DNA sequence analyzer. After family. Results:We identified point mutation of TGC (Cys)→CGC (Arg) at codon 618 of the RET proto-oncogene exon 10, using the automatic DNA sequence analyzing method on the index patient and detected the same point mutation with 4 of the 9 family members. Among them, the index patient and her mother who had biochemical and clinical symptoms underwent a total thyroidectomy and neck disection and are now being folowed up;operations are scheduled for two other members later on. Conclusion:test and that more complete aproach through early diagnosis would be posible by carrying out the screning test for point mutation in patients with the hereditary medulary thyroid carcinoma .

방사선 치료 후 국소 재발한 성문암에서 구제 수술로서의레이저 성대 절제술

최소희,이강대,문효성,김성원,김영록,유태현 대한이비인후과학회 2007 대한이비인후과학회지 두경부외과학 Vol.50 No.2

Background and Objectives:Salvage surgery for recurrent glotic cancer after radiation failure has been reported in the li-terature as a treatment for total laryngectomy and partial laryngectomy (vertical partial laryngectomy, supracriocoid partial la-ryngectomy) in selected cases. Also, CO2glotic cancer. However, salvage laser surgery for recurrent glotic cancer has been rarely reported. Our experience of transoral laser cordectomy on recurent glottic cancer after radiotherapy is reported. Subjects and Method:Twelve patients with early recurrent glottic cancer after full-course radiotherapy (rT1a, n= 4;rT1b, n= 1;rT2, n= 7) underwent laser cordectomy between October, one type IV, and eight type V performed. One patient underwent type II at one side and type II at the other. Surgery in all the cases were performed at one stage with curative intent. Results:The mean follow-up interval was 30 months (range 17- 44 months) with five out of 12 cases (42% ) having local recurence. Four of the five cases with local recurence underwent total laryn-gectomy. Thre cases were salvaged while one had additional recurence. The other one was under palliative treatment. The local (range 2- 26 days) after surgery, and tracheotomy was performed in four cases (duration:3- 20 days). There was no postope-rative aspiration pneumonia and nasogastric tube was not performed in any of the cases. Conclusion:Transoral laser microsurgery may be a feasible salvage method for recurent glottic cancer to gain oncologic and functional results, and could be used as an or-gan-preserving procedure with curative intent in selected cases. (Korean J Otolaryngol 2007 ;50 :139-44)

Small molecular solar cells with new non-fullerene acceptor

성민재,황민주,문상훈,이택호,박송이,김진영,최효성,김윤희,권순기 한국고분자학회 2018 한국고분자학회 학술대회 연구논문 초록집 Vol.43 No.1

제 1 형 다발성 내분비선종증을 가진 한 가계의 유전자 변이 분석

이강대,김주연,문효성,최소희,이환호,최영식,박요한,Shinya Uchino 대한이비인후과학회 2005 대한이비인후과학회지 두경부외과학 Vol.48 No.3

Background and Objectives:MEN I is an autosomal dominant disorder characterized by multiple tumors occurring in the parathyroid, pituitary, and pancreas. There is a variety of mutations in MEN I that are scatered throughout the coding region, thus MEN I family has its unique type of mutations. The aim of this study is to investigate the significance of genetic screning via analyzing the MEN I gene in the MEN I family. Subjects and Method:Three family members related to MEN I were involved for studying the MEN I gene mutation by using single strand conformational polymorphism and DNA sequence an-alysis of the coding region and the exon-intron boundaries of the MEN I gene. Results:A specific germline mutation of 1023 a to g transition at the splice aceptor site of exon 7 was identified in all three members of the family in the direct sequence analysis of MEN I gene. Conclusion:Genetic analysis for mutations in the MEN I family allows identification of individuals predisposed only in genetic counselling of clinical management of the MEN I families but also in reducing health care expenses and psycho-logical burden of the diseases.

두경부암 환자의 객담으로부터 Common MAGE Primer를 이용한 MAGE A1-6 mRNA의 검출의 의의 - 예비 보고

이강대,손성환,문효성,이영수,정헌,김주연,이환호,장희경,전창호,박종욱 대한이비인후과학회 2003 대한이비인후과학회지 두경부외과학 Vol.46 No.12

Background and Objectives:We have reported that the expression of MAGE gene is specific to the mRNA level or protein level in head and neck cancer tissues. In this study, we investigated the applicability of MAGE gene to molecular diagnosis of head and neck cancer by detecting MAGE mRNA with common MAGE primers in sputa of patients. Materials and Method: Nested RT-PCR with MAGE common primers were designed by authors and were performed to detect MAGE 1, 2, 3, 4a, 4b, 5a, 5b, and 6 (MAGE A1-6) genes in sputa obtained from 22 cancer patients (17 squamous cell carcinoma of laryngopharynx, 2 lung metastsis after surgery for tongue and hypopharyngeal cancer, 2 neck metastasis from primary lung cancer, and 1 case of sarcoma of hypopharynx) and 40 normal persons. Results:Of 17 sputa from squamous cell carcinoma patients, expression of MAGE mRNA was positive in 13 (76.5%) cases. MAGE was detected in 72.7% (8/11) of laryngeal cancer, 50% (1/2) of base of tongue cancer, and 100% in hypopharyngeal (2/2) and tonsillar cancer. According to T stage, T1, T2, T3, T4 was positive in 50% (2/4), 100% (5/5), 66.6% (2/3), and 80% (4/5) respectively. In case of primary lung cancer, metastatic lung cancer, and hypopharyngeal sarcoma, all expressed MAGE mRNA. Among 22 cancer patients, 81.8% (18/22) were positive. MAGE expression was detected in 5% (2/40) of the normal control. Conclusion:Nested RT-PCR with common MAGE primers was helpful for assessing the presence of cancer cell in the sputa of the respiratory tract. This examination can be used as a tumor marker for the screening of laryngopharyngeal cancers and early detection of recurrent cancers or lung metastasis after treatment. (Korean J Otolaryngol 2003;46:1070-6)

왈틴씨 종양에서 기원한 다형성 저등급 선암종 1예

이강대,이형신,문효성,허방 대한이비인후과학회 2006 대한이비인후과학회지 두경부외과학 Vol.49 No.2

Warthins tumor is the second most common benign tumor of the parotid gland. Malignancy arising from Warthins tumor is extremely rare, and only 29 cases have been reported. Diagnosis can be made prior to the surgery, but in many cases, the disease is detected through postoperative pathology report or by recurrence of the mass lesion. We report a case of polymorphous low grade adenocarcinoma arising from Warthins tumor diagnosed by the excision of a parotid mass and treated by an additional surgery of superficial parotidectomy. The postoperative pathology report revealed no residual cancer cells and the patient is free of disease for 8 months since the operation. (Korean J Otolaryngol 2006;49:232-5)