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고압호모지나이저처리가 TEMPO산화 셀룰로오스의 나노해섬도에 미치는 영향
김보연,한송이,원종명,이승환 한국공업화학회 2014 한국공업화학회 연구논문 초록집 Vol.2014 No.1
고압호모지나이저 처리는 큰 전단력과 간단한 조작법으로 셀룰로오스 나노섬유의 제조에 있어 일반적으로 사용되는 방법이다. 본 연구에서는 TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl radical) 촉매로 산화된 표백 활엽수 펄프의 나노해섬도에 미치는 고압호모지나이저 처리 횟수의 영향을 조사하였다. 원자력간 현미경을 사용하여 단섬유의 치수를 측정하고 나노해섬도를 관찰하였으며 비표면적을 측정하여 해섬도를 평가하였다. 비표면적 측정용 샘플은 최대한 나노섬유의 응집을 억제하기 위하여 t-butyl alcohol로 용매치환 후 동결건조 방법으로 제조하였다.
정신분열병 환자의 병식에 대한 정신병리와 약물순응도의 관계
김보연,이창욱,박종원 대한신경정신의학회 1993 신경정신의학 Vol.32 No.3
The authors studied insight in order to investigate its relationships to psychopathology and drug compliance in the schizophrenic patients. The subjects were 60, acutely and subacutery hospitalized patients who had relapsed more than one time. A measure of insight reflecting patients’ recognition of their illness and need for treatment was revalidated against ratings from a semistructured interview after translation and modification of the original questionnaire of McEvoy et als(19811989). The measure of drug compliance was performed by the use of original method of Van Puttens(1974). Degree of insight was consistently related to the degree of drug compliance but not severity of acute psychopathology. Nor did changes in insight during hospitalization vary consistently with changes in acute psychopathology. After running mutiple regression to see the effect of the explanatory variable including demographic variable, psychopathology and drug compliance to insight it was revealed that only drug compliance was the reponse variable in equation which had explanatory power with 8% and 23% each time. The authors discussed the possibility of existence of other variable such as socialization after admission which might explain insight on the other aspects. The authors also dicussed that the impairment of cognitive function might be reponsible for poor insight in schizophrenia. As a result these data suggest that only little of the deficiency in insight in schizophrenic patients is explanable on the basis of psychopathologic feature.
김보연,이봉희,성수일,진병래,강필돈,황재삼,장종수,박남숙,이상몽 한국잠사학회 2005 International Journal of Industrial Entomology Vol.10 No.1
In our research to identify gene involved in the cuticle protein, we cloned a novel cuticle protein gene,ApCP15.5, from the Chinese oak silkmoth, Antheraea pernyi, larvae cDNA library. The gene encodes a 149 amino acid polypeptide with a predicted molecular mass of 15.5 kDa and a pI of 9.54. The ApCP15.5 contained a type-specific consensus sequence identifiable in other insect cuticle proteins and the deduced amino acid sequence of the ApCP15.5 cDNA is most homologous to Tenebrio molitor-C1B (43% protein sequence identity), followed by Locusta migratoria-76 (42% protein sequence identity). Northern blot and Western blot analyses revealed that the ApCP15.5 showed the epidermis-specific expression. The expression profile of ApCP15.5 indicated that the ApCP15.5 mRNA expression was detected in the early stages after larval ecdysis and larval-pupal metamorphosis, and its expression level was most significant on the first day of larval ecdysis and pupal stage. The ApCP15.5 was expressed as a 15.5 kDa polypeptide in baculovirusinfected insect cells.
도시가로변 건축물 외장색채의 분포조사에 관한 연구 : 제주시 탑동지역을 중심으로
김보연,박철민 제주대학교 산업기술연구소 2001 尖端技術硏究所論文集 Vol.12 No.1
Appraising an image of a city, we first consider a street landscape, which depends on its shape and colors and so on outside colors of building are affected by features of location and symbolic meanings in buildings. Therefore, A purpose of this study is to realize we have any need to plan colors of buildings to make a beautiful street of a city and to search for Jeju landscape. The procedure to satisfy the purpose is as following : First, I studied a theory of colors, Second after choosing Top-Dong as a place to have JeJu peculiar characters. I surveyed the present condition of colors on the street and analyzed it to see if there are problems on it. Third, I suggested better alternatives by looking up Jeju peculiar colors, based on studies in the reference. It is expected that this study helps an appropriate plan of environmental colors improve the identity of the area.
김보연,목지오,정찬희,김재욱,이승원,김철희,강성구 연세대학교의과대학 2012 Yonsei medical journal Vol.53 No.5
Purpose: We evaluated whether the clinicopathological factors of papillary thyroid microcarcinoma (PTMC), especially tumoe size, are associated with subcinical central lymph node metastasis. Materials and Methods: A total of 160 patients diagnosed with PTMC who underwent total thyroidectomy with bilateral central lymph node dissection were enrolled in this study. All patients were clinically lymph node negative PTMC. Patients were divided into 2 groups according to the size of tumor (≤5 mm vs. >5 mm). Clinicopathologic risk factors for subclinical central lymph node metastasis were analyzed. Results: Subclinical central lymph node metastasis was detected in 61 (38.1%). Patients with tumors ≤5 mm had a lower frequency of extrathyroidal extension, multifocality and subclinical central lymph node metastasis. On multivariate analysis, only male and tumor size >5 mm were independent predictors of subclinical central lymph node metastasis; age, multifocality, bilaterality, extrathyroidal extension, lymphvascular invasion and lymphocytic thyroiditis were not. Conclusion: In this study, male and tumor size >5 mm were two independent predictive factors for subclinical central lymph node metastasis in PTMC. These are easier factors to assess before surgery than other factors when planning the central lymph node dissection. However, further long-term follow-up studies are needed to confirm the prognostic significance of subclinical central lymph node metastasis in PTMC.
고등학생의 폰 중독 및 인터넷 게임중독과 스트레스 반응: 수면부족의 매개효과를 중심으로
김보연,서경현 한국건강심리학회 2012 한국심리학회지 건강 Vol.17 No.2
This study investigated how phone addiction and internet game addiction are related to the stress responses of adolescents. The study examined the mediating effects of sleep deprivation between these relationships. The participants were 475 male and female high school students, whose ages ranged from 14 to 19. Researchers developed items to measure phone addiction. The addiction to internet game, sleep deprivation, and stress responses were also measured. In the different types of phone addiction, gender differences was found. Futhermore, males were more likely to show an addiction to internet games more than females, whereas females were more likely to experience sleep deprivation more than males. The correlational analysis results indicated that both phone addiction and internet game addiction were positively correlated with sleep deprivation as well as stress responses. Sleep deprivation shared approximately 16% of the variance with stress responses. In the hierarchial regression analyses, sleep deprivation was the mediating variable of phone addiction or internet game addiction and stress responses. It partially mediated these relationships. These results suggest that if high school students become addicted to the phone or to internet games, they easily become sleep derived, and thus, they portray various kinds of stress reponses. 본 연구에서는 청소년의 폰 중독이나 인터넷 게임중독이 스트레스 반응과 어떤 관계가 있는지를 탐색하고, 그 관계를 수면부족이 매개하는지 검증하였다. 본 연구의 참여자는 남녀 고등학생 475명이었으며, 연령 분포는 만 14세에서 19세 사이였다. 본 연구에서는 폰 중독을 측정할 수 있는 문항들을 개발하였고, 인터넷 게임중독, 수면부족 및 스트레스 반응도 측정하였다. 분석 결과, 폰 중독 양상에 성차가 발견되었으며, 인터넷 게임중독 수준은 남자 청소년에게서, 수면부족 수준은 여자 청소년에서 더 높게 나타났다. 상관분석에서는 폰 중독과 인터넷 게임중독 모두가 수면부족은 물론 스트레스 반응과도 정적 상관이 있었다. 수면부족도 스트레스 반응과 약 16%의 변량을 공유하고 있었다. 위계적 회귀분석에서는 수면부족이 고등학생의 폰 중독이나 인터넷 게임중독과 스트레스 반응 간의 관계에서 매개변인으로 작용하는 것으로 나타났다. 수면부족은 그 관계들을 부분적으로 매개하고 있었다. 이런 결과는 고등학생이 폰 중독이나 인터넷 게임중독에 빠질 경우 수면이 부족하게 되고 그 결과 스트레스 반응을 보이게 될 수 있음을 시사한다.