한국토양비료학회 발표요지 : 답토양에 있어서 규산과 인산의 상호관계에 대하여

백남인,임선욱 한국토양비료학회 1982 한국토양비료학회 학술발표회 Vol.1982 No.28

腦性麻痺로 因한 Swan-neck Deformity와 Thumb in Palm Deformity의 治驗 1例

白南仁,金德永,邊永壽,李弘鍵 최신의학사 1977 最新醫學 Vol.20 No.5

There is a small group of patients with cerebral palsy who can be benefited by reconstructive surgery on the upper extremity. In cerebral palsy long standing muscle imbalance, which can be improved only by surgical treatment, may prevent a hand from reaching its full potential for function. This case is a 18 yrs old girl had a flexed wrist, swan neck deformity of the fingers and a clasped thumb. She was treated by surgical measure of the tenodesis of the flexor sublimis tendon at the proximal interphalangeal joints of the index; transference of flexor carpi radialis to abductor pollicis brevis: and myotomy of adductor pollicis. We obtained very good result without other complication.

식용 식물자원으로부터 활성물질의 탐색-IV. 달래(Allium monanthum Max.)로부터 Galactosyldiglyceridem의 분리

백남인,안은미,김해영,박영두,장영진,김세영 한국생명과학회 2001 생명과학회지 Vol.11 No.1

n-BuOH fraction obtained from MeOH extracts of Allium monanthum was applied to repeated silica gel column chromatographies to give a glycosylglyceride. The chemical structure of the compound was determined to be 1-O-linolenoyl-2-O-linolenoyl-3-O-$\beta$-D-galactopyranosyl-누-glycerol on the basis of NMR data and by the adaptation of chemical methods.

산딸나무(Cornus kousa Burg.)의 열매로부터 sterol 화합물의 분리

백남인,이대영,송명종,김성훈,정인식,김대근,박미현,권병목 한국작물학회 2006 한국작물학회 학술발표대회 논문집 Vol.2006 No.-

Steroids from the Aerial Parts of Artemisia princeps Pampanini

백남인,이대영,최명숙 한국약용작물학회 2006 韓國藥用作物學會誌 Vol.14 No.5

Three stigmastane-type sterols and one ergostane-type sterol were isolated from the ethyl acetate soluble fractionof the aerial parts of Artemisia princeps Pampanini (Sajuarissuk). From the results of physico-chemical data includingNMR, MS and IR, the chemical structures of the compounds were determined as stigmasta-5,22-dien-3β-ol (stigmasterol, 1),stigmast-5-en-3β-ol (β-sitosterol, 2), 5,8-epidioxy-5β,8β-ergosta-6,22-dien-3β-ol (ergosterol peroxide, 3), and β-sitosterol 3-O-β-D-glucopyranoside (daucosterol, 4).

損傷骨端成長板의 骨架橋 抑制에 關한 實驗的 硏究

白南仁,邊永壽 고려대학교 의과대학 1982 고려대 의대 잡지 Vol.19 No.1

The post-traumatic deformity resulting from the injury of the epiphyseal plate in the growing child is the matter of the great disaster in the orthopedic field and the prevention of those deformities is the important task for orthopedic surgeons. Several experimental studies on pathophysiology of bone bridge formation after growth plate injury have been reported but the prevention of ti has been controversial. To observe bone bridge formation after surgical manipulation for the injury of growing epiphyseal plated, forty-five rabbits weighing 700-1,000gm were divided into following 3 groups each group comprising of 15 rabbits. Group Ⅰ : Injuries to the epiphyseal plate with Kirschner wire. Group Ⅱ : Transplantation of autogenous fat tissue into the defect of the injured epiphyseal plate produced by K-wire. Group Ⅲ : Interposition of medical silicone rubber implant into the defect of the injured epiphyseal plate produced by K-wire. The animals were sacrificed at 2,4,6,8 and 12 weeks after the experimental procedures and the histological examination of the injured epiphyseal plated of distal femur were made. The results obtained are as follows: 1. In group Ⅰ, all fifteen cases started to form new osseous tissue from the fourth week, all of which developed to bone-bridge at the twelfth week between the metaphysis and the epiphysis. 2. In group Ⅱ, transplanted fat tissue was mostly necrotized at the second week which was replaced with fibrous tissue between the second to the twlfth week. And the bone bridge was observed one case each at the fourth, sixth, and eighth week and two cases at the twelfth week. 3. In group Ⅲ, thirteen out of fifteen cases did not from bone bridge up to the twelfth week. and only thin bone bridge was observed on case each at the eighth and twelfth week. 4. Prevention of bone bridge formation was ten out of fifteen cases (66.7%) in group Ⅱ and thirteen out of fifteen cases (86.7%) in group Ⅲ. The above mentioned results clearly show that implant of the medical silicone rubber is better than autogenous fat tissue in preventing the bone bridge formation across the traumatized epiphyseal plate.

알팔파(Medicago sativa L .)로부터 지표성분의 분리

백남인,안은미,방면호,김무성,한재택 한국국제농업개발학회 1998 韓國國際農業開發學會誌 Vol.10 No.2

1. 알팔파 MeOH 추출물의 n-BuOH 분획으로부터 silica gel column chromato- graphy를 반복하여 glycosyl diglyceride 화합물을 분리하였다. 2. 화합물의 화학구조를 NMR, IR 등의 기기분석 결과와 산 및 알칼리 가수분해 반응을 이용하여 (2S)-1-O-linolenoyl-2-O-linolenoyl-3-O-[α-D-galactopyranosyl (1→6)-β-D-galactopyranosyl]-sn-glycerol 로 결정하였다. 3. 구성지방산의 종류 및 조성은 알칼리 분해하고 methyl ester 화한 후 GC/MS를 이용하여 분석한 결과 linolenic acid (84.2%), linoleic acid (7.2%), palmitic acid (5.2%), oleic acid (2.2%), stearic acid (1.2%)으로 결정되었다. The MeOH extracts obtained from the whole plants of Medicago sativa L. were fractionated with solvent system of EtOAc, n-BuOH, and H₂O, successively. From the n-BuOH extract, a major component, a glycosyldiglyceride compound, was isolated through the repeated silica gel column chromatographs. On the basis of several spectral data and hydrolysis results, its chemical structure was determined to be (2S)-1-O-linolenoyl-2-O-linolenoyl-3-O-[α-D-galactopyranosyl (1→6)-β-D-galactopyranosyl]-sn-glycerol. The kind and composition of fatty acids in the glyceride were determined through alkaline hydrolysis, methyl esterification, and followed by GC/MS such as ; linolenic acid (84.2%), linoleic acid (7.2%), palmitic acid (5.2%), oleic acid (2.2%) and stearic acid (1.2%).

식용식물자원으로부터 활성물질의 탐색-XXII. 사자발쑥 (Artemisia princeps PAMPANINI)의 지상부로부터 Triterpenoid의 분리

백남인,방면호,조진경,송명종,이대영,한민우,정해곤,정태숙,이경태,최명숙 한국응용생명화학회 2008 Journal of Applied Biological Chemistry (J. Appl. Vol.51 No.3

The aerial parts of Sajabalssuk (Artemisia princeps PAMPANINI, Sajabalssuk) was extracted with 80% aqueous MeOH, and the concentrated extract was partitioned with EtOAc, n-BuOH and H2O, successively. From the EtOAc fraction, three cycloartane-type triterpnoids and one ursanetype triterpenoid were isolated through the repeated silica gel, ODS and Sephadex LH-20 column chromatographies. From the results of physico-chemical data including NMR, MS and IR, the chemical structures of the triterpenoids were determined as wrightial (1), wrightial acetate (2), 27- norcycloart-20(21)-ene-25-al-3β-ol acetate (3) and ursolic acid (4). No report has been found for isolation of compound 3 in the literature so far, and compounds 1, 2 and 3 were the first to be isolated from Sajabalssuk (Artemisia princeps PAMPANINI, Sajabalssuk). Also, compound 1 showed Acyl-CoA:Cholesterol acyltransferase (hACAT-1) and hACAT-2 inhibitory activity with the IC50 values of 33.0 and 45.0 μg/ml, respectively. Compounds 2 and 3 inhibited hACAT-1 activity with the IC50 values of 12.0 and 16.0 μg/ml, respectively. The aerial parts of Sajabalssuk (Artemisia princeps PAMPANINI, Sajabalssuk) was extracted with 80% aqueous MeOH, and the concentrated extract was partitioned with EtOAc, n-BuOH and H2O, successively. From the EtOAc fraction, three cycloartane-type triterpnoids and one ursanetype triterpenoid were isolated through the repeated silica gel, ODS and Sephadex LH-20 column chromatographies. From the results of physico-chemical data including NMR, MS and IR, the chemical structures of the triterpenoids were determined as wrightial (1), wrightial acetate (2), 27- norcycloart-20(21)-ene-25-al-3β-ol acetate (3) and ursolic acid (4). No report has been found for isolation of compound 3 in the literature so far, and compounds 1, 2 and 3 were the first to be isolated from Sajabalssuk (Artemisia princeps PAMPANINI, Sajabalssuk). Also, compound 1 showed Acyl-CoA:Cholesterol acyltransferase (hACAT-1) and hACAT-2 inhibitory activity with the IC50 values of 33.0 and 45.0 μg/ml, respectively. Compounds 2 and 3 inhibited hACAT-1 activity with the IC50 values of 12.0 and 16.0 μg/ml, respectively.

幼若家兎의 關節軟骨 및 骨端成長板에 Kirschner wire 및 screw 揷入이 미치는 影響에 關한 實驗的 硏究

白南仁,邊永壽 고려대학교 의과대학 1976 고려대 의대 잡지 Vol.13 No.1

The effect of surgical traumata upon the epiphyseal plate of the growing bone has been controversial among many authors. The resultant deformity subsequent to the epiphyseal plate injury yields numerous different pattens and any of the explarations of the pathogenesis is also not accepted for all. Therefore, the author made an experiment to elucidate more clearly the histological changes of the epiphyseal plate of immature rabbits following insertion of Kirschner-wire and screw. Thirty rabbits weighing 700-1200gm mere divided into 2 groups, as following and the direction of longitudinal insertion form articular surface of the epiphysis into metaphysis of the distal femur. Group 1: Insertion of Kirschner-wire Group 2: insertion of screw The animals were sacrificed at 1,2,4,8, and 10 weeks after the operative procedure and the histological examination of the injured epiphyseal plate of distal femur were made. The summary of the histological findings were follows: 1. The margin of the epiphyseal plate adjoining the Kirsckner wire showed a new osseous tissue which formed a bony bridge running from the epiphysis to the metaphyseal bony trabeculae. 2. The margin of the damaged epiphyseal plate adjoining the screw revealed new bone formation and the amounts of the reactive new bone is less than Kirschner-wire. 3. Histological findings of the epiphyseal plate showed to be uniform and normal except in the adjacent area of the Kirschner-wire and screw.

달래 (Allium grayi R.)로부터 이차대사산물의 분리, 동정

백남인,안은미,방면호 한국토양비료학회 2000 한국토양비료학회 학술발표회 초록집 Vol.2000 No.5