정상 체중인 성인 남성에서 지방과다와 심혈관질환의 위험요인간의 관련성

권우성,김준수,채진욱,이근미,정승필,문용 영남대학교 의과대학 2003 Yeungnam University Journal of Medicine Vol.20 No.1

정상체중을 가진 성인 남성에서 지방과다(adiposity)와 심혈관계 질환의 위험요인과의 관련성을 알아보고자 하였다. 2001년 1월 3일부터 12월 31일까지 영남대 학교의료원에서 종합검진을 받은 만 28∼69세 성인 남성 129명을 대상으로 연령, 신체계측, 혈압, 공복 혈당, 혈청 지질대사치와 체성분 검사를 실시하였다. 체질량지수(BMI)가 18.5∼23 kg/㎡(76명)인 정상체중군과 23∼25 kg/㎡(53명)인 과체중군으로 분류하고, 체비방률, 체지방량과 위험인자들(수축기혈압, 이완기혈압, 공복시 혈당, 중성지방, 저밀도지단백, 고밀도지단백)의 상관관계를 분석하고, 정상체중군을 지방과다에 따라 3군으로 나누고, 각 군과 과체중군에서 심혈과 질환의 위험인자를 평가하였다. 정상체중의 제1군을 기준으로 제2, 3군과 과체중군의 위험인자 존재에 대한 비차비(odds ratio)를 조사하였다. 정상체중군에서 지방과다 변수들(adiposity variables: 체지방량, 체지방률)과 수축기 및 이완기 혈압, 저밀도지단백, 중성지방에서 유의한 상관관계가 있었다. (P<0.01). 나이를 보정하고 난 뒤 제1군을 기준으로 제3군(체지방율: 3.7, 체지방양: 4.7)과 과체중군(체지방율: 6.6, 체지방양 11.5)에서 위험인자에 대해 더 높은 비차비를 가졌다. 지방이 많은 정상체중의 성인남성은 적은 지방을 가진 성인 남성보다 심혈관 질환에서 더 높은 유병 위험도를 가졌다. 지방 측정은 정상체중군에서 심혈관계 질환의 위험인자외에 추가적인 정보를 제공할 수 있었다. Background: Most of all studies about the relation between the health risk and obesity are based on the European and American data. The purpose of this study is to examine the relation between adiposity and factors for cardio vacular disease (CVD) in normal weight individuals. Materials and Methods: Normal weight subjects with a body mass index (BMI) between 18.5 and 23 kg/㎡(76 subjects) and overweight subjects with a BMI between 23 and 25 kg/㎡ (53 subjects) were retained for this study. Normal weight subjects were divided into three group of each adiposity variable, then three group and the overweight group were evaluated for the presence of CVD risk factors and analyze the correlation coefficients between adiposity variables and risk factors controlled for age in normal weight, overweight groups. Using logistic regression analysis, the odds ratio (OR) for the prevalence of risk factors for each group of adiposity variables and the overweight group was estimated relative to the first group in normal weight subjects. Results: Systolic BP, diastolic BP, LDL cholestrol, HDL cholesterol, triglycerides in normal weight subjects were significantly correlated with all adiposity variables (P<0.01). Third group (3.7 for %fat and 4.7 for fat mass) of adiposity variables in the normal weight group and the overweight group (6.6 for %fat and 11.5 for fat mass) tended to have higher ORs compared to first group for risk factor variables. Conclusion: Normal weight subjects with elevated adiposity had higher prevalence of risk factors than normal weights subjects with less adiposity. Measuring of adiposity added additional information of cardiovascular disease risk factors in normal weight subjects.

비타민 K₁피부 과민반응 2예

정우권,김영근,황규왕,박영립,이홍규 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.1

Vitamin K₁ is frequently used in the treatmet of the hypoprothrombinemia found in diseases of the liver, biliary tract and small intestine. We observed allergic cutaneous reaction to vitamin K₁injection in two patients who developed pruritic erythematous indurated plaques at the sites of injection 8 to 14 days after subcutanceous injection of vitamin K₁preparation.

변형된 미끄럼 탐색 기법을 이용한 고속 프랙탈 영상압축

오우진,권상근 金烏工科大學校 1998 論文集 Vol.19 No.-

Fractal image coding applies the self-similarity of image. But it takes long time to search for the self-similarity block. To shorten the searching time. we proposed the modified sliding search algorithm which employs the classification of variance of range and domain blocks. For some blocks which have small variance, only mean value of range block is transmitted without searching. Compared with sliding search algorithm, our algorithm shows 15% lower in bit rate and 21% gain in searching time, but PSNR decreases only 0.05 dB.

수도관의 생물막 형성에 미치는 잔류염소와 파이프 재질의 영향

박세근,박재우,성권식,최성찬,김영관 江原大學校 産業技術硏究所 2001 産業技術硏究 Vol.21 No.B

This laboratory study examined the impact of free chlorine residual and pipe material on the formation of biofilm in drinking water distribution pipe surfaces. Result of heterotrophic plate counts(HPC) of the biofilm in the tap water- supplied reactor averaged 2.17×105CFU/cm2 on PVC and 2.43×105CFU/cm2 on STS 316, respectively. HPCs on the surface exposed to the tap water containing 0.2mg/L of free chlorinne residual averaged 4.24×104CFU/cm2 on PVC and 6.54×104CFU/cm2 on STS 316, respectively Average of HPC/Total direct counts in the tap water-supplied reactor ranged from 1.08%(PVC) to 1.26%(STS 316) and from 0.38%(PVC) to 0.65%(STS 316) in the reactor supplemented with disinfectant, resfectively. No correlation was observed between disinfectant addition and biofilm density. With regard to the biofilm formation, little difference existed between PVC and STS 316. Yellow and red pigmented bacteria were the dominant expressions in bulk fluid, whereas non-pigmented bacteria were found dominant in the biofilm. Pink/red pigmented bacteria were found to be facultative anaerobic, while yellow pigmented bacteria and non-pigmented bacteria were found to be obligate aerobic.

Holstein種의 血液化學値에 關한 硏究 : Ⅱ. 송아지와 未産牛의 血液化學値 Ⅱ. Blood Chemical Values of Calves and Heifers

金宇權,韓邦根,鄭璣柝 全南大學校 農漁村開發硏究所 1984 農業科學技術硏究 Vol.19 No.-

國內에서 飼育되고 있는 Holsrein種 송아지와 未産牛의 血液化學植를 얻고자 全南地域에서 飼育되고 있는 外觀上 健康하다고 認定된 송아지 및 未産牛 180頭를 對象으로 血液化學植를 調査檢討하여 다음과 같은 結論을 얻었다. 1. 血淸의 平均化學植는 TP量이 5.89(4.1~8.5)g/100ml, Alb量이3.26(2.0-4.3)g/100ml, Glb量이 2.61(1.1-5.8)g/100ml, cholesterol量이 104.13(44.0-297.0), glucose量이 54.12(31.9-96.0)mg/100ml, Mg量이 2.59(0.02-8.60) mg/100ml, P量이 7.09(3.6-9.4)mg/100ml, Ca量이 4.41(3.4-5.4)mEq/l, K量이 5.08(4.0-6.7)mEq/L, Na量이 139.82(130-150) mEq/L, Cl量이 99.87(84.6-115.3)mEq/L 이었다. 2. 血淸의 A/G比는 1.25(0.40-3.33)이었으며 CA/P比는 1.25(0.83-2.28) 그리고 Na/K比는 27.52(21.49-35.00) 이었다. 3. 血淸의 Alb量과 Na/K比는 1個月未滿牛의 植가 特히 낮았으며 Ca量은 전반적으로 낮은 植이었다. 4. 血淸의 TP量과 Glb量은 月齡의 增加에 따라서 減少하여 6個月未滿牛에서 가장 낮은 植를 이루고 다시 점차 增加함을 볼 수 있었으나 A/G比는 月齡의 增加에 따라서 增加하여 6個月未滿牛를 頂点으로 다시 下向의 傾向을 나타내고 있었다. 5. 血淸의 Glucose, Ca, P 및 重量은 月齡의 增加에 따라서 점차 減少하는 傾向이 있었으나 Ca/P比는 月齡의 增加와 더부러 漸漸 增加하는 傾向이 있었다. 6. 血淸의 cholesterol, Mg, Na 및 Cl量에서는 月齡別로 數植上의 多少의 差異点은 있었으나 어떤 特徵的인것은 發見할수 없었다. The present study was conducted to determine the blood chemical values of Holstein calves and heifers in Korea. Blood samples were taken from 180(♀ 123, ♂ 57) healthy calves and heifers in Chonnam province. The results obtained in this study were summarized as follows. 1. The content of mean serum total protein (TP), albumin(Alb) and globulin(Glb) was 5.87(4.1-8.5), 3.26(2.0-4.3) and 2.61(1.1-5.8)g/100ml respectively. The concentration of mean serum cholesterol, glucose, magnesium(Mg) and inorganic phosphate(P) was 104.13(44.0-297.0), 54.12(31.9-96.0), 2.59(0.02-8.60) and 7.09(3.6-9.4)mg/100ml respectively. The concentration of mean serum calcium(Ca), potassium (K), sodium(Na) and chloride(Cl) was 4.41(3.4-5.4), 5.08(4.0-6.7), 139.82(130-150)and 99.87(84.6-115.3)mEq/L respectively. The ratio of mean serum albumin to globulin(A/G), calcium to inorganic phosphate(Ca/P) and sodium to potassium(Na/K) was 1.25(0.40-3.33), 1.25(0.83-2.28) and 27.52(21.49-35.00) respectively. 2. The Alb content and Na/K ration appeared to be especially lower in the age group of less than 1 month than in the other age groups, and the Ca concentration was low compared with other results. 3. The content of TP and Glb decreased to the age group of less than 6 months and thereafter it tended to increase with aging, whereas the reverse was the case with A/G ratio. 4. The concentration of glucose, Ca, P and K tended to decrease with aging, whereas the reverse was the case with Ca/P ratio. 5. No differences were found in the concentration of cholesterol, Mg, Na and Cl between various age groups.

Holstein種의 血液像에 關한 硏究 : Ⅱ. 송아지와 未産牛의 血液像 Ⅱ. Hematologic Values of Calves and Heifers

金宇權,韓邦根 全南大學校 農漁村開發硏究所 1981 農業科學技術硏究 Vol.16 No.2

, In order to get the normal blood values of Holstein calves and heifers in Korea, blood samples were taken from 180(♀123, ♂57) healthy calves and heifers Chonnam province. The results obtained in the present study are as follows: 1. Determined average red blood cell count was 5.61(4.00∼9.96)×10??/㎕, whereas average red blood cell count obtained from the results in the normal range(normal) was 6.19(5.08∼9.23)×10??/㎕. The red blood cell count appeared to decrease with age. 2. Determined average hemoglobin content was 10.40(6.5∼15.3)g/100㎖, whereas normal hemoglobin content was 11.20(9.3∼14.4)g/100㎖. The hemoglobin content tended to decrease with age. 3. Determined average packed cell volume(PCV)was 31.43(22∼46)㎖/100㎖, while normal PCV was 33.75(28∼43)㎖/100㎖. The PCV tended to decrease with age. 4. Determined mean corpuscular volume(MCV) was 56.02(35.71∼70.00) fl. Normal MCV was 54.52(42.25∼61.87) fl, which was lower than the determined MCV. 5. Determined mean corpuscular hemoglobin concentration(MCH) was 18.54(12.35∼24.00) pg. Normal MCH was 18.09(14.01∼20.58) pg, which was lower than the determined MCH. 6. Determined mean corpuscular hemoglobin concentration(MCHC) was 33.09(24.21∼40.83)g/100㎖. Normal MCHC was 33.19(28.33∼36.33)g/100㎖, which was higher than the determined MCHC. 7. Determined average white blood cell(WBC) count was 9,681(3,590∼18, 630)/㎕ whereas normal WBC count was 9,104(4,780∼13,184)/㎕. The WBC count tended to increase with age. 8. In the normal WBC differential count, the values were lymphocyte 67.83(44∼86)%, monocyte 2.63(0∼8)%, neutrophil 26.57(8∼53)%, eosinophil 2.48(0∼9)% and basophil 0.49(0∼2)%, respectively. No differences were found between the determined and normal values. 9. Lymphocyte count appeared to increase with age, while the reverse was the case with neutrophil count. 10. Determined average platelet count was 261,981(119,000∼964,000)/㎕, whereas normal platelet count was 283,064(135,000∼964,000)/㎕, which was slightly higher than the determined platelet count. The platelet count between age groups appeared to be higher in the age groups of 1 day to 1 month and 2 months to 3 months than the other age groups.

反芻動物의 Hemoglobin型에 關한 硏究

金宇權,李載洪,金五南,林貞澤,韓邦根 全南大學校 農漁村開發硏究所 1977 農業科學技術硏究 Vol.12 No.-

牛와 緬羊 그리고 山羊의 hemoglobin phenotype 및 遺傅子의 出現頻度를 檢討하고자 牛 460頭(韓牛 430, Holstein 30), 緬羊 214頭(Corriedale 140 Polworth 74), 山羊 150頭(在來山羊 黑色種 60, 在來山羊 白色種 40, Saanen 雜種 50)에 對하여 寒天 gel 電氣泳動法을 實施하여 다음과 같은 結果를 얻었다. 1. 牛의 hemoglobin phenotype는 HbAA, HbAB, HbBB, HbAC 그리고 HbAD의 5型으로 나타났으며 이들의 出現頻度는 HbAA型이 78.70%, HbAB型이 20.00%, HbBB型이 0.43%, HbAC型이 0.43%, 그리고 HbAD型이 0.43%이었다. hemoglobin型, 支配遺傅子은 ??, ??, ?? 그리고 ??의 4種으로 그 出現頻度는 ??가 89.13%이고 ??가 10.43%이며 ??와 ??는 名名 0.22%이었다. 단지 Holstein種은 hemoglobin phenotype가 HbAA型과 HbAB型만이 나타났으며 그 出現頻度는 HbAA型86.67%이고 HbAB型이 13.33%이었다. Holstein種의 hemoglobin 支配遺傅子는 ??와 ??의 2種으로 그 出現頻度는 ??가 93/33%이었고 ??가 6.67%이었다. 2. 緬羊의 hemoglobin phenotype는 HbAA, HbAB 그리고 HbBB의 3型으로 나타났으며 이들의 出現頻度는 HbAA型이 63.08%, HbAB型이 29.91% 그리고 HbBB型이 7.01%이었다. hemoglobin型 支配遺傅子는 ??와 ??의 2種으로 그 出現頻度는 ??가 78.04%이었고 ??가 21.96%이었다. Carriedale種과 Polworth種과는 hemoglobin型에는 差異가 없었으나 型의 出現頻度와 그 支配遺傅子의 出現頻度에는 큰 差가 있었다. 즉 Corriedale種는 hemoglobin phenotype의 出現頻度가 HbAA型이 80.71%이며 ??의 出現頻度는 89.64%나 되었으나 Polworth의 hemoglobin phenotype의 出現頻度는 HbAA型이 29.73%이며 HbAB型이 52.70%로 가장 많았으며 ??의 出現頻度가 43.92%나 되었다. 3. 山羊의 hemoglobin phenotype는 全部 同一型으로 나타났으며 牛나 緬羊의 HbAA型에 類似하였다. The hemoglobin phenotypes and the gene frequencies of 460 cattle(430 Korean native cattle, 30 Holstein), 214 sheep(140 Corriedale, 74 Polworth) and 150 goats(60 black Korean native goats, 40 white Korean native goats, 50 Saanen hybrid) were examined by agar gel electrophoresis. The results obtained were as follows; 1. In cattle hemoglobin phenotypes, HbAA, HbAB, HbBB, HbAC and HbAD were observed and their frequencies of appearence were 78.70, 20.00, 0.43, 0.43, and 0.43 per cent respectively. The distribution of gene frequency were calculated 89.13 in ??, 10.43 in ??, 0.22 in ?? and 0.22 per cent in ??. Among the cattle hemoglobin phenotypes two hemoglobin types, HbAA and HbAB, were observed in Holstein and their frequencies of appearence were 86.67 and 13.33 per cent respectively. The distribution of gene frequency were calculated 93.33 in Hb?? and 6.67 per cent in ??. 2. In sheep hemoglobin phenotypes, HbAA, HbAB and HbBB were observed and their frequencies of appearence were 63.08, 29.91 and 7.01 per cent respectively. The distribution of gene frequency were calculated 78.04 in ?? and 21.96 per cent in ??. The distribution of gene frequency of Hb?? was 89.64 per cent in Corriedale but 56.08 per cent in Polworth. 3. Only one hemoglobin type was found in the goats and the type was similar to the HbAA type which was showed in cattle and sheep.

류마티스 관절염 환자에서 발생한 Mycobacterium intracellulare에 의한 관절염 1예

박근우,권현희,정승혜,김경찬,최정윤,이영환 대한감염학회 2007 감염과 화학요법 Vol.39 No.1

비정형 항산균에 의한 근골격계 감염은 매우 드물며, 진단이 지연되는 경우가 많다. 저자들은 류마티스 관절염환자에서 수차례 스테로이드 주사 후에 생긴 M. intracellulare에 의한 관절염을 진단하고 수술적 치료없이 약물 치료만으로 좋은 결과를 보인 예를 경험하였기에 보고하는 바이다. Nontuberculous mycobacteria are ubiquitous organisms that are frequently present in the water, soil and animal reservoirs. Nontuberculous mycobacterial infections of the musculoskeletal system are rare and usually associated with predisposing factors, such as prior joint disease, trauma, use of intraarticular or oral corticosteroids, or an immunocompromised state. A sixty five-year-old patient with rheumatoid arthritis was hospitalized due to swelling on the left wrist. M. intracellulare was cultured from the aspirated joint fluid. The patient was successfully treated with clarithromycin, ethambutol, and rifampin. We report this case with review, emphasizing high suspicion for nontuberculous mycobacterial infection in patients with predisposing risk factors.

하수슬러지를 이용한 복합소재 개발연구

연규석,권윤환,유근우,김남길,김동준,이윤수 강원대학교 부설 석재복합신소재 제품연구센터 2002 석재연 논문집 Vol.7 No.-

본 연구는 하수 종말 처리에 의해 발생되는 하수 슬러지를 잔 골재(경량골재)로 사용하여, 폴리머 콘크리트를 제조하여 그 때의 역학적 성질에 대하여 검토하였다. 하수 슬러지는 5일간 110±5℃에서 수분함량 0.1%미만으로 건조한 후 파쇄하여 No.4∼No. 200 번체의 잔골재 표준 시방서 기준에 부합되도록 사용하였다. Pellet는 보통 회전pan에서 만드나, 본 실험에서는 수동으로 제조하였다. 제조한 하수 슬러지 경량 골재는 평균 겉보기 비중은 1.58(g/㎤), 단위용적중량은 1.98(t/㎥)으로 KS F 2534의 경량골재의 절건비중과 단위용적에 따른 분류에 의하면 중위급(medium weight) 경량골재에 속하는 것으로 측정되었다. 또한 잔 골재 중 하수 슬러지 경량 골재를 0%, 5%, 10%, 15%, 20%, 25%, 30%로 치환하여 그때의 압축, 휨, 인장강도를 측정하였다. 그 결과 하수 슬러지의 증가에 따라 강도 감소를 보였으나, 일반 경량콘크리트 제조 또는 단열용 콘크리트 블록 제조에 사용이 가능하다고 사료된다. 그러므로 앞으로 건조수축, 크리이프 특성 및 내구성에 관한 연구가 더욱 심도 있게 이루어져야 폐자원인 하수 슬러지를 이용한 건자재의 개발이 가능하리라 판단된다. In this study, the polymer concrete was produced by using the lightweight aggregate that had been manufactured using the sewage sludge and its physical properties were experimentally examined. Experimental results show that when the portion of sewage sludge lightweight aggregate in the fine aggregate increases, slump values decreases. Also, the compressive, the flexural and the tensile strengths decrease when the portion of sewage sludge lightweight aggregate increases. Although its strengths decreases, the sewage sludge lightweight fine aggregates is thought to be used for construction materials.

호산구성 간농양 54예의 임상상

강혜련,권혁수,송우정,이상민,김태범,박혜경,장윤석,김윤근,조상헌,민경업,김유영 대한알레르기학회 2004 천식 및 알레르기 Vol.24 No.2