동씨침을 시술한 안면경련의 치험 3례

김태우,김효은,조명제,강영화,이재동,Kim, Tae-woo,Kim, Hyo-eun,Cho, Myung-je,Kang, Young-hwa,Lee, Jae-dong 대한침구의학회 2003 대한침구의학회지 Vol.20 No.1

Objective : Hemifacial spasm is painless uncommon disorder characterized by involuntary paroxysmal movement of one side of face, In this study, the effect of Dong-Si acupuncture therapy for three patients with hemifacial spasm were evaluated. Methods : We have treated them with acupuncture treatment of Dong-Si acupuncture points(Cheuk-Samni and Cheuk-ha-Samni) and evaluated the effect by Scott's scale, For the first two weeks, it was dine once a day, and after two weeks, the other day. Results : Before therapy, the grades of spasm intensity classified by Scott's description in three cases were 3. And after Dong-Si acupuncture therapy, the grade of one case was 0, and two cases were 1. Conclusion : The Dong-Si acupuncture therapy for hemifacial spasm was effective and will be attempted to the patients with it.

관상동맥내 스텐트 삽입후 발생한 관상동맥류 2례

제인수,허민영,문치숙,이재호,정수룡,조길현,이영민,김대경,김두일,김동수 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3

Coronary artery aneurysms are detected with increasing frequency because of the routine use of coronary angiography in the diagnosis and management of coronary artery disease. Although some coronary artery aneurysms are congenital or inflammatory, most are atherosclerotic. The prognosis of atherosclerotic coronary artery aneurysm may depend on the morphology of the aneurysm or the presence of coexisting obstructive disease. Coronary artery aneurysms have been also reported to occur after ballon angioplasty, directional athrectomy, laser angioplasty, and stent implantation with a frequency of 2% to 4%. The long-term outcome of post-intervention coronary artery aneurysm is unknown. We report two cases of the development of a coronary aneurysm 6 months after stent implantation as a treatment of severe obsructive coronary artery disease.

낮병원 치료 : 2년간 추적연구

조맹제,이부영,신동수 大韓神經精神醫學會 1994 신경정신의학 Vol.33 No.1

저자들은 1989년 1월 1일부터 1990년 12월 31일까지 서울대학교병원 낮병원에서 퇴원한 만성정신분열병 환자 30명을 같은 기간 보호병동에서 퇴원한 정신분열병 환자 30명과 성별, 연령, 주치의의 예후에 대한 평가등을 1:1로 짝지워 총30쌍, 60명을 대상으로 낮병원 입원이 환자의 예후에 미치는 영향을 기준 퇴원후 2년간을 후향적 추적방법으로 비교 연구하였다. 결과는 다음과 같다. 1) 추적기간동안 양군의 사회인구학적인 변인은 통계적으로 의미있는 차이를 보이지 않았다. 사회인구학적 변인 중 기준 퇴원시 학력과 이전 입원횟수에서 유의한 차이를 보였다. 2) 재입원율, 재입원횟수, 재입원환자수, 누적재입원횟수, 누적재입원환자수 등의 일반 예후변인에서 통계적으로 유의한 차이가 없었다. 단지 낮병원군에서 기준 퇴원후 1년간의 재입원율이 통계적으로 유의하게 더 컸는데, 2년후 전체 재입원율에 있어서는 양군이 유사하였다. 3) 사회적응도에 있어 양군에서 유의한 차이를 발견할 수 없었다. 단지 낮병원군에서 재입원한 환자들 (n=6)의 경우 시간이 지남에 따라 사회적응정도가 향상하는 양상을 보였다. 또한 기존의 연구들에서 퇴원후 주로 6개월 내지 1년 이내에 입원에 의한 사회적응효과가 나타난다고 했으나 본 연구에서는 오히려 추적 기간의 후반부에 사회적응도가 향상하는 경향을 보여 저자들은 이점에 대해 낮병원에서의 사회적응훈련이 '후기 효과'를 보일 가능성에 대해서 토론하였다. 본 연구의 결과만으로 낮병원 치료가 정신분열병환자의 예후에 어떠한 영향을 미치는가에 대한 확실한 결론은 얻을 수 없었다. 그러나 유병기간이 더 길고 사회적응이 어렵다고 판단된 낮병원 환자들과 보호병동군을 비교한 결과 기준퇴원후 2년간 각 예후변인들이 유의한 차이가 없었던 것은 낮병원 치료가 만성 정신분열병 환자의 사회재적응에 장기적으로 도움이 되었기 때문이라고 추론할 후 있다. 향후 본 연구에서는 고려되지 못한 정신분열병의 예후에 관련이 있는 좀더 많은 변수들을 충분히 고려한 전향적 연구가 필요하다. A two year retrospective follow up analysis of outcome was done comparing 30 chronic schizophrenic patients discharged from standard in-patient hospital to day hospital treatment with 30 matched patients discharged directly to the community. The authors developed an 80 item interview questionnaire for sociodemographic characteristics, social functioning, family functioning, psychopathology and rehospitalization. Index numbers of rehospitalization within two years were six in day hospital group, and eight in the comparative group respectively. When the duration was divided into three month intervals, cumulative percentage of number of patients rehospitalized was lower in the day hospital group. Readmission rate calculated by rehospitalization days divided by total follow-up days was, however, higher significantly in the day hospital group within one year. It seemed that this result within one year was due to the bias of selection of day hospital patient. That is, the poorer prediction of community adjustment by the psychiatrist was related with the day hospital treatment. Social functioning score checked on the rehospitalized patients showed little difference between the two groups.

레니텍^(�) 정(말레인산 에날라프릴, 10mg)에 대한 에나레이스 정의 생물학적 동등성

조성희,하용화,홍성제,서성훈,류재환,김동현,이경태 한국약제학회 2003 Journal of Pharmaceutical Investigation Vol.33 No.3

The purpose of present study was to evaluate the bioequivalence of two enalapril maleate tablets, Renitec^(™) (MSD Korea Ltd.) and Enalace ^(™) (Welfide Korea Ltd.), according to the guidelines of Korea Food Drug Administration (KFDA). Twenty-four normal male volunteers, 22.33±2.55 year in age and 66.54±8.30 ㎏ in body weight, were divided into two groups and a randomized 2×2 cross-over study was employed. After two tablets containint 10 ㎎ of enal-april maleate per tablet wre orally administered, blood was taken at predetermined time intervals and concentrations of enalapril in plasma were determined using LC-MS-MS. Pharmacokinetic parameters such as AUC_(t), C_(max) and T_(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC_(t) and C_(max) untransformed T_(max). There were no sequence effects between two formulations in these parameters. The 90% confidence intervals for the log transfored data were acceptance range of log0.8 to log1.25(e.g., log1.02∼log1.14 and log1.03∼log1.19 for AUC_(t) and C_(max), respectively). The major parameters, AUC_(t) and C_(max), met the criteria of KDFA for bioequivalence indicating that Enalace^(™) tablet is bioequivalent to Renitec^(™) tablet.

中國 會社法上 土地使用權 出資에 관한 연구

趙東濟 한국기업법학회 2003 企業法硏究 Vol.14 No.-

The basic concept formed by the 1988 amendments to the Constitution is the separation of land use rights from the ownership of land. Subsequently, a series of laws and regulations have been promulgated to perfect the legal framework of China' s land use system. According to the Constitution, all land located in urban areas is owned by the State, while the land in mal and city suburban areas is collectively owned. Collective owners of land generally include farmer economic collectives, village communities or township farmers collectives. In other words, all land is publicly owned by either the State or the collectives. On the other hand, land use rights are distinguished as type of intangible property, and may be sold by the State to various land users including companies, enterprises, organizations, or individuals for value. Land users who have acquired land use rights from the State may, in a further step, sell or transfer in some other way, the land use rights to third parties, but the land always remains in public ownership. It is critical for investors to locate a good site and acquire legally transferred land. As detailed above, the land use rights may be obtained mainly by means of transfer, lease, allocate, purchase or equity contribution. Each method involves different legal implication, requirements and procedures. Therefore, foreign investors have to take all necessary precautions to examine the origin of land and distinguish the nature of transfer. It must be ensured that all necessary legal procedures have been gone through and every land-related document is in place.

한국 주요정신장애의 유병률 및 관련요인 : 2006 전국정신질환역학조사

조맹제,장성만,함봉진,정인원,배안,이영문,안준호,원승희,손정우,홍진표,배재남,이동우,조성진,박종익,이준영,김진영,전홍진,이해우 大韓神經精神醫學會 2009 신경정신의학 Vol.48 No.3

Objectives The aims of this study are to estimate the prevalence of the DSM-IV psychiatric disorders in the Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI), and to compare those with previous studies. Methods The Korean Epidemiologic Catchment Area study Replication (KECA-R) was Conducted between August 2006 and April 2007. The sampling of the subjects was carried out across 12 catchment areas. A multistage, cluster sampling design was adopted. The target Population included all eligible residents aged 181o 64 years. Face-to-face interviews were conducted with the Korean version of Composite International Diagnostic Interview (K-CIDI) based on the DSM-IV (N=6,510, response rate=81.7%). Results A total of 6,510 participants completed the interview. The lifetime and 12-month prevalence rates for all types of DSM-IV disorders were 30.0% and 17.3%, respectively. Those of Specific disorders were as follows : 1) alcohol use disorder, 16.2% and 5.6% ; 2) nicotine use disorder, 9.0% and 6.0% ; 3) specific phobia, 3.8% and 3.4% ; 4) major depressive disorder, 5.6% and 2.5% ; and 5) generalized anxiety disorder, 1.6% and 0.8%. Data relating to nicotine and alcohol use disorder revealed a very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among females than males. Conclusion The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in the distribution of psychiatric disorders across the country and times were observed.

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

One Arm Curl 동작의 Simulation

조동욱,서국웅,윤양진,김정태,조승제 釜山大學校 附設 體育科學硏究所 1997 體育科學硏究所 論文集 Vol.13 No.-

In recent years, numerical simulation of human body motion has received an increasingly wider range of application. Computer simulations have greatly contributed to the understanding of kinematics and dynamics of human motion. Such simulations are being used in ergonomics to better understand and thus improve the interaction of persons with machines and with workplace configurations. In sports, the simulations are being used to optimize performance, to develop equipment for injury prevention, and to speed and enhance recovery from injury. Then in this study simulated one arm curl motion for understanding force and moment in arm's each joint, and this segment modeling was used 2-dimension, 3-link system. From simulation of mathematica 3.0 we found kinematic and kinetic factors with imaginatively lift of dumbbell and simulated random value of the last curl angle, weight of dumbbell, cycle of motion and so on. The conclusions of this study is as follows ; 1. As this study link system, weight of dumbbell influence not a stance and motion but magnitude of force and moment. 2. The force showed even as smooth curve in all cycle. Moment showed biggist between 0.5sec and 1.5sec. The magnitude order is shoulder, elbow and wrist joint. 3. Motion of system in this study is very similar human arm's motion considering that law of inertia and helped effectively delegation of force. 4. Mathematica is useful language as simulation program. Forward it needs study about modeling and simulation on muscle factors, also human body simulation.

한국어판 Composite International Dianostic Interview(K-CIDI)의 개발

조맹제,함봉진,서동우,홍진표,배재남,김장규,이동우,조성진 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.1

연구목적 : 본 연구는 국제적인 정신장애 진단도구인 Composite International Diagnostic Interview(CIDI)를 한국의 사회문화적 상황에 적합하게 번역하고 신뢰도 및 타당도를 평가하여 한국어판으로 개발하기 위한 것이다. 방 법 : CIDI는 정신장애를 평가하고 진단할 수 있는 포괄적이고, 완전히 표준화된 진단도구로 훈련받은 일반인들이 적용할 수 있기 때문에 대규모 역학조사에 적합하다. 세계보건기구에서 제공하는 CIDI 번역 지침에 따라 한국어판 CIDI(K-CIDI)를 제작하였다. 영어권과 한국의 언어 및 사회문화적 차이를 고려하여 번역 및 개정을 하였고 역번역을 통하여 원본의 의미와 일치하는지를 확인하였다. 임상환자를 135명과 일반인 5명을 대상으로 신뢰도와 타당도 검사를 실시하였다. 두 명의 평가자가 K-CIDI를 이용하여 동일한 대상자를 동시에 면담하고 일주일 뒤에 재검사를 실시하였다. K-CIDI로 검사를 받은 대상자들을 정신과 전공의와 임상심리사가 한국어판 Structured Clinical Interview for DSM-Ⅳ를 이용하여 진단을 내렸다. 두 가지 진단의 일치도에 대한 kappa값을 산출하였다. 결 과 : CIDI의 번역에서 한국어 표현이 복잡하고 긴 문항은 두 개의 문장으로 분리하였고, 성과 관련된 표현과 의료체계 및 의료추구행태에서 사회문화적 차이를 반영하였다. 공포장애의 대상과 알코올 및 물질의 종류도 한국의 실정에 맞게 조정하였다. 현장 검사와 역번역 과정에서 K-CIDI가 적절하게 제작된 것으로 평가되었다. K-CIDI의 평가자간 신뢰도 검사는 140명에 대하여 이루어졌고 kappa값은 진단에 따라 0.86∼1.00범위였다. 검사/재검사 신뢰도 검사는 47명에 대해 이루어졌고 kappa값은 진단에 따라 0.42∼0.89였다. K-CIDI의 타당도 검사는 50명에 대해 이루어졌고 kappa값이 진단에 따라 0.50∼1.00의 범위였다. 결 론 : K-CIDI는 한국의 사회 문화적 배경에 적합하게 제작되었고 신뢰도 및 타당도 검사에서 역학연구에 적절한 진단도구로 평가되었다. Objectives : This study aims to develop a Korean version of the Composite International Diagnostic Interview(K-CIDI). Methods : The Composite International Diagnostic Interview(CIDI) is a comprehensive, fully standardized interview that can be used to assess psychiatric disorders and provide diagnoses. The K-CIDI was developed according to the guidelines provided by the WHO. The reliability and validity of the K-CIDI was evaluated by examining 135 psychiatric patients and five community residents. Subjects were jointly interviewed twice with a one-week interval. A psychiatric resident and clinical psychologist jointly determined clinical diagnoses using the Structured Clinical Interview for DSM-Ⅳ. Results : Notable modifications were done on sex-related expression, health system and help seeking behavior, subjects for phobic disorder, and kinds of alcohol and substance. Long and complex questions were divided into two or more questions. Field test and back-translation of the K-CIDI confirmed the appropriateness of the translation of the CIDI. The inter-rater reliability, test/retest reliability, and validity of the K-CIDI indicated kappa values ranging from 0.86-1.00, 0.42-0.89, and 0.50-1.00, respectively. Conclusion : The K-CIDI was deemed to be appropriate for the sociocultural background of Koreans. The reliability and validity of the K-CIDI were judged to be exceptionally acceptable.

中國 外國人投資企業 法規範에 관한 小考

趙東濟 東亞大學校 法學硏究所 2004 東亞法學 Vol.- No.34