최근 9년간 신경정신과에 입원한 환자에 대한 임상적 고찰(1972∼1980년)

이정호,안일남,오석환,정영조,최영민,원장섭,김영훈,하혜경,이승탁,이영주 인제대학교 1983 仁濟醫學 Vol.4 No.2

정신질환 환자들에 대한 정확한 생태를 파악함은 정신 건강과 치료 대책을 세우는데 중요하다. 이에 본 저자들은 1972년부터 1980떤 사이에 인제의대 부속 서울백병원 신경정신과에 입원하여 치료 받았던 환자들에 대한 제반 요인들을 분석 검토하였다. Clinical charactristics of neuropsychiatric inpatients were evaluated and discussed with special referrence to their diagnostic distribution. All discharged cases from neuropsychatric ward of Seoul Paik Hospital during nine years from 1972 to 1980 were 2863. Among them 813 cases were discarded from this study because their clinical charts were vague in description of failed to find out. The materials of this study were extracted from 2050 discharged cases. Total number of cases of inpatients were gradually increasing by each year from 1972 to 1980. Psychoneurosis was diagnosed in 45.2%, schizophrenia in 26.9%, organic brain syndrome in 8.9%, major affective disorder in 5.5%, personality disorder in 4.8%, other psychiatric disorder in 1.5%, psychophysiologic disorder in 1.0%, mental retardation in 0.5%, paranoid state in 0.5%, and other psychosis in 0.3%. The gruop of patients, ranging in age from 21 to 40 was the highest (75.2%) in this study. Male patients were 43.9% and female patients were 56.1%. Schizophrenia leas diagnosed in 32.9%, depressive neurosis in II.3%, anxiety neurosis in 9.3%, and personality disorder in 8.1% in male patients. Hysterical neurosis was diagnosed in 25.5%, depressive neurosis in 22.2%, schizophrenia in 22.2%, and anxiety neurosis in 7.0% in female patients. The authors evaluated the route of admission of patients. Sixty-eight point three percent of total studied cases were admitted through outpatient department, 20.9% of cases were admitted through emergeney room, and 8.2% of cases were transfered from other department or hospital. Among patients who were admitted to psychiatric wards through emergency room and transferred from other department or hospital, psychoneurosis was the hightest diagnostic group in rate. Most of patients who were transferred from other department or hospital were from Internal Medical Department. There were no relationship between seasonality of admission and diagnostic group in this study. readmission rate of total studied patients in neuropsychiatric department of Seoul Paik Hospital was 30%. The readmission rate of personality disorder, mental retardation, schizophrenia, and major affective disorder were relatively high. The cases who were discharged against medical advice were 441. Among them misunderstanding about psychiatric treatment was predominent. Twenty seven percent of patients had physical illness at or during admission. The patients who were diagnosd as psychophysiological disorder had physical illness in 42.8%, 35.4% in personality disorder, 33.9% in major affective disorder, and 24.3% in schizophrenia. About nine percent of total studied cases had the history of attempted suicide. Major affective disorder, Personality disorder, Deressive neurosis, and Other Psychosis showed high incidence of history of attempted suicide prior to admission.

철도교통안전진단제도 발전방향 제시

정연욱(Yeun Wook Jung),이주영(Ju Young Lee),김영선(Young Sun Kim),노남진(Nam Jin Noh),이승열(Seung Yeoul Lee),송병호(Byung Ho Song) 한국철도학회 2015 한국철도학회 학술발표대회논문집 Vol.2015 No.10

철도실시설계단계에서 이용자 중심의 안전성을 강화하고자 교통안전법 및 교통안전진단 지침이 개정됨으로써 14 년 10 월 13 일 철도교통안전진단제도가 시행되었다. 이후 중앙선, 하남선 등 15 개 철도건설사업 실시설계에 대하여 철도교통안전진단이 시행되었고, 그 결과 이용자 및 열차운행측면에서의 안전위험요인이 도출 및 개선되었다. 본 연구에서는 철도교통안전진단제도가 보다 더 실효성 있게 시행될 수 있도록 진단대상 · 진단시기 등을 명확화 하였고, 진단항목 고도화를 위하여 기존 진단항목 보완 및 신규진단항목을 개발하였다. 이와 함께, 철도교통안전진단에 대한 평가제도 도입의 필요성 및 시행방안을 제시하였다. To enforce safety of passenger at enforcement design stage of rail, Railroad Traffic Safety Diagnosis is introduced at Oct 13, 2014 by revising Traffic Safety Act and Traffic Safety Diagnosis. Railroad Traffic Safety Diagnosis is implemented about enforcement design which is for 15 railroad construction like Jung-Ang Line and Ha-Nam Line, therefore, danger factors about safety are deducted and improved in respect of passenger and train operation. In this study, diagnosis object, diagnosis time and other article are clarified for effectiveness of the Safety Diagnosis and diagnosis articles are supplemented and developed for enhancement. In addition, necessity and execution plan of evaluation system are proposed.

40세 이하 관상동맥 질환자에서 장기적 임상 관찰

이승욱,정명호,박종철,박형욱,조상희,김원,김계훈,이상현,강경태,조장현,김남호,김건형,안영근,조정관,박종춘,강정채 全南大醫大 2001 전남의대학술지 Vol.37 No.2

만성 B형 간염에서 라미부딘 치료중 발생한 Viral Breakthrough 예의 임상 결과

안수현,장윤정,오성남,최도원,백수정,정원석,최창원,김경오,임형준,조남영,박종재,김재선,박영태,이명석,연종은,변관수,이창홍 대한간학회 2002 Clinical and Molecular Hepatology(대한간학회지) Vol.8 No.4

목적: 만성 B형 간염의 치료 중 발생하는 약제 내성 변이종은 임상적으로는 치료 중 음전되었던 혈청 HBV DNA가 다시 양전되는 viral breakthrough 로 진단할 수 있다. 현재 약제 내성 변이종이 발생했을 경우라도 라미부딘 치료를 계속 유지하는 것을 권장하고 있으나, viral breakthrough 발생 예들의 장기적 임상경과가 아직도 불명확하여 이것을 일반화하기는 어려운 상황이다. 이에 라미부딘 사용 중 viral breakthrough 가 발생한 예들을 대상으로 그 임상경과를 알아보고자 하였다. 대상과 방법: 9개월 이상 라미부딘을 투약한 만성 B형 간염 환자로 viral breakthrough가 발생한 74명을 대상으로 하였다(남/여 54/20, 평균연령 42세). Viral breakthrough 후 혈청 ALT치, 총 빌리루빈치, HBV DNA 역가, HBeAg, anti-HBe를 정기적으로 검사하면서 임상경과를 관찰하였다. Viral breakthrough 후 라미부딘의 투약기간은 평균 13개 월(1-41개월)이었다. 결과: Viral breakthrough 발생후 혈청 ALT치가 정상으로 유지되었던 환자는 8예(11%)에 불과했고 나머지 66예(89%)에서는 ALT치가 증가하였으며, 이중 30예(41%)에서 급성 악화(ALT 정상 상한치의 5배 이상 상승)를 보였다. 급성악화는 viral breakthrough 후 3개월 내에 19예 (63%)에서 발생하여 3개월 내에 발생한 예가 많았으나 12개월 이상 지나서 나타나는 예도 약 20%에서 있었다. 비대상성 악화는 6예에서 관찰되었다. Viral breakthrough 후 급성악화가 일어난 예와 없었던 예의 비교에서 급성악화를 예측할 수 있는 인자는 발견할 수 없었다. Viral breakthrough 후 발견할 수 없었다. Viral breakthrough 후 HBeAg이 음전된 예는 8예(11%)였으나 그 임상경과는 양호하지 않았다. 결론: 만성 B형 간염 환자 에서 라미부딘 투여 중 발생한 viral breakthrough 예 중 상당수에서 급성악화가 발생하였으며, HBeAg 이 소실되더라도 그 임상경과는 양호하지만은 않았다. Viral breakthrough 발생 후 주의 깊은 임상경과 의 관찰이 요구되며, 앞으로 viral breakthrough 후 급성악화 예에 대한 대규모 연구와 적절한 치료방향의 제시가 이루어져야 할 것으로 생각된다. Background/Aims: Long-term lamivudine therapy can induce the emergence of lamivudine resistant hepatitis B virus (HBV) mutants. Clinically emergence of the mutant is expressed by the reappearance of disappeared HBV DNA in serum. Continued lamivudine treatment has been usually recommended in cases of viral breakthrough. However, the clinical outcome in patients with viral breakthrough is not clear. The aim of this study was to investigate the clinical course of chronic hepatitis B patients after viral breakthrough during lamivudine therapy. Methods: A total of 74 patients with chronic hepatitis B who showed viral breakthrough after at least 6 months of lamivudine treatment were included in this study. They had positive HBeAg and HBV DNA before treatment. The median follow-up duration after breakthrough was 13 months. Results: After viral breakthrough, only 8 patients (11%) maintained normal ALT levels and 66 patients (89%) showed elevation of ALT. 30 patients (41%) showed acute exacerbation of hepatitis (ALT increase over five-times upper normal limit). These acute exacerbations occurred within three months after breakthrough in 19 patients (63%). In the cases of acute exacerbation, 6 patients showed decompensated progression such as elevation of serum total bilirubin. One of them died of hepatic failure. A predictive factor for acute exacerbation was not found. HBeAg seroconversion occurred in 8 patients after viral breakthrough but their clinical course was highly variable. Conclusions: Chronic hepatitis B patients who had viral breakthrough during lamivudine therapy should be followed carefully and regularly in mind of potential clinical deterioration. New strategies are needed to manage the cases of acute exacerbation after viral breakthrough.(Korean J Hepatol 2002;8:389-396)

대동맥 협착증과 동반된 출혈성 위장관 동정맥 기형에서 Estrogen-Progesterone 치료 1예

김도연,김화정,김효정,남준식,박수영,박영미,신정은,주미순,황민규,정혜경,손혜영,이선영,이한주 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

산업자재용 폴리에스터 섬유의 강도 향상에 관한 연구

박영신,남영식,정상영,최재호,장기혁,박원호,Park, Young-Shin,Nam, Young-Sik,Jung, Sang-Young,Choi, Jae-Ho,Jang, Ki-Hyuk,Park, Won-Ho 한국섬유공학회 2012 한국섬유공학회지 Vol.49 No.1

In this work, effects of total draw ratio change on the mechanical properties of polyester fibers were studied. The process parameter was a total draw ratio and the draw ratios that were used ranged from 6.6 to 7.0. Tensile properties are determined from the tensile tester, and crystallite parameters from the density measurement and X-ray diffraction were discussed with the different total draw ratios. The tenacity, young's modulus and crystallinity were increased to 10.6 g/d, 123.2 g/d and 42.1%, respectively, with increase in the total draw ratio. The relations between total draw ratio and mechanical properties of high tenacity polyester fiber were discussed.

고령자 남녀와 20대 남녀에 있어서 다양한 등속수축중 최대 모멘트의 비교

金智源(Ji-Won Kim),金相佑(Sang-Woo Kim),文基旭(Ki-Wook Moon),嚴光文(Gwang-Moon Eom),李泳揆(Young-Gyu Lee),南貞淑(Jung-Sook Nam),朴寬龍(Kwan-Yong Park),金耀翰(Yo-Han Kim),洪廷和(Jeong-Hwa Hong),朴炳奎(Bung-Kyu Park) 대한전기학회 2008 전기학회논문지 Vol.57 No.10

In this paper, we investigated the maximum ankle joint plantarflexion moment (MPM) of young and elderly subjects during various modes of isokinetic contractions with special interest in the elderly females who were reported to have higher fall rate than the elderly males. Subjects include the young subjects (14 males: 22.7±2.5yrs, 13 females: 20.5±1.3yrs) and the elderly subjects (17 males: 65.8±10.5yrs, 26 females: 71.4±5.2yrs). The MPM was normalized by each subject's body weight. The MPM of elderly females was the weakest among the groups, particularly, at the eccentric contractions. The male-to-female ratio of MPM was greater in the elderly than in the young and the young-to-elderly ratio of MPM was greater in female than in male, both during the eccentric contractions. The result suggests that the decreased muscle force per body weight, especially at the eccentric contraction, may be one reason for the more frequent fall of the elderly female than the elderly male.

지역사회 정신보건사업을 위한 환자 발견 체계에 관한 연구 : Case Detection and Delivery Method

남정현,박준혁,박용천,신영전 漢陽大學校 精神健康硏究 1998 精神健康硏究 Vol.17 No.-

GIS를 이용한 수문매개변수에 관한 연구

정남선,김영균 서강정보대학 2002 論文集 Vol.21 No.-

The main objective of this study is to extract the hydro-Parameter of the Tamjin River basin. A GIS is capable of extracting various hydrological factors from DEM(digital elevation model). One of important tasks for hydrological analysis is the division of watershed. In this study, watershed itself and other geometric factors of watershed are extracted from DEM by using GIS technique. The data of topographical map with scale of 1:25,000 and 1:250,000 in the Tamjin River basin is used for this study and it is converted to DEM date. Various forms of representation of spatial data are handled in main modules and a GRID module of ArcView. A GRID module is used on a stream in order to define watershed boundary. Based on the spatial analysis using those GIS technique, it would be possible to obtain the reasonable results of watershed characteristics. The stream network itself of watershed and the other characteristics of stream network are generated, which can be defined by the relationship of flowdirection and cell size of Tamjin River basin as follws ; - the relationship of total stream length(km) between the count of flowaccumulation Y=14633.45^(*)X^(-0.552345) where, Y is total stream, length and X is the count of flowaccumulation - the relationship of total stream length between the cell size(m) Y=23567.73^(*)X_(c)^(-1.112332) where, Y is total stream, length and is the cell size From the above equation, it can be concluded that the optimal count of flowaccumulation is 432 and cell size is 48m for spital analysis by using GIS technique in Tamijin River basin. Also, the results show not only that GIS can aid watershed management, research and surveillance, but also that the geometric characteristics as parameters of watershed can be quantified more accurately and easily than conventional graphic methods.

연질폴리우레탄폼의 물리적 성질 및 흡음율에 관한 연구

정종원,박남국,박선정,박종래,김영철 全南大學校 觸媒硏究所 1997 觸媒硏究 論文集 Vol.19 No.-

The effects of polyols, isocyanates. surfactants and water on the physical properties of the polyurethane foam were investigated. The resin used in this study was prepared from a variety of polyol mixtures by adding catalyst, surfactant and cross-linker. The polyurethane was foamed from the resin by adding an equivalent amount of isocyanate and was used in property measurements. The physical properties were more affected by the type of isocyanates and the amount of water than the sound absorption coefficient. The sound absorption coefficient of the polyurethane foam was superior for the polyol mixture of KE-810(40%)FA-733(40%)/FA-703(20%). The sound absorption coefficient was increased with the amount of surfactant L-5309 up to 3000Hz, but was decreased above that frequency.