http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
수복재에 함유된 불소가 치질의 미세경도와 불소 함유량에 미치는 영향
이수종,조영곤,김종욱,박병철 大韓齒科保存學會 2004 Restorative Dentistry & Endodontics Vol.29 No.1
The purpose of this study was to compare the microhardness and the fluoride content of enamel and dentin around fluoride- or non fluoride-containing restorations. Forty extracted human teeth were used and prepared cervical cavities on proximal surface. Experimental teeth were divided into five groups. Group 1 : Prime & Bond NT and Z100. Group 2 : Prime & Bond NT and F2000. Group 3 : Scotchbond Multi-Purpose and Z100. Group 4 : Scothcbond Multi-purpose and F2000. Group 5 : Fuji II LC. The cavities were filled with dentin adhesives and restorative materials. After each tooth was bisected, one half was tested microhardness and the other half was analyzed the fluoride at the enamel and dentin by an EPMA-WDX device. The results were as follows: 1. There was no statistical difference among the microhardness of enamel surface in all group. 2. The microhardness at dentin of 100 ㎛ point in Group 2 and 20 ㎛ point in Group 4 was lower than that of normal dentin (p>0.05) 3. There was no statistical difference among the fluoride content of enamel surface in all group. 4. The fluoride content at the dentin of 30 ㎛ point in Group 2 and 5 were higher than those at 100 ㎛ and 200 ㎛ point in Group 2 and normal dentin (p<0.05) 5. At the dentin of 30 ㎛ point, Group 2 showed higher fluoride content than Group 1 and 3, and Group 5 showed higher fluoride content than other groups.
조백기,박종갑,김형옥,김성욱,백승철,김진우,김시용,안규중,전재복,오지원,김낙인,이규석,오칠환,김수남,김상태,손숙자,신용우,김동석,이원우,권경술,서대헌,황규왕,이종석,고재경,강원형,정기양,최응호,김기홍,박석돈,강승주,함정희,명기범,김방순,구상완,김병수,원영호,김한욱,송은섭,정병수,노병인,홍창권,박장규,한지윤,김광중,구대원,김종민,김재홍,유희준,양경미 대한의진균학회 1998 대한의진균학회지 Vol.3 No.2
Background: Onychomycosis, especially toenail onychomycosis has become one of the common fungal infection and has historically been regarded as a cosmetic rather than medical problem by many patients, even by physicians. Recently, however, there are several reports that is a refractory disease which may cause a deleterious effect on patiets quality of life (QOL). Objective: The purpose of this study was to investigate the impact of toenail onychomycosis on QOL in Korea and to assess the chandes of QOL after treatment. Methods: Total 1004 patients with toenail onychomycosis which was confirmed by clinical findings and KOH preparation were were enrolled at 47 dermatologic centers in Korea, and interviewed with standardized QOL questionnaire before and after sytemic antifungal treatment. Responses to the questionnaire were scored by 5-point scale (1∼4) and averaged, and were analyzed for 5 dimensions of emotional impact, social impact, symptorn and functional impact, patients views concerning treatment, and relationship with doctor. Results: 1. Before and after treatment, the most serious impact was emotional dimension showing 1.90 and 1.30 in average score (AS), and social (AS: 1.14 and 0.83) and symptom and functional impact (AS: 1.05 and 0.92) was also affected. 2. In female rather than male, statistically more significant impact on patients QOL was observed in all dimensions. 3. After treatment, 3 of 5 dimensions were improved significantly - emotional dimension (AS : from 1.90 to 1.30), social dimension (AS: from 1.14 to 0.83), patients view concerning treatment (AS: from 1.34 to 1.02). 4. The drgree of patients satisfaction at the therapeutic effect was very high- 62.4% (immediately after treatment) and 65.8% (9 months affer initiation of treatment) of patients answered excellent or good. Conclusion: This study confirms that toenail onychomycosis has significant impact on the overall QOL of patients. Also the effect of antifungal therapy on patients QOL were watisfactory. Therefore, both doctor and patient should pay more attention to the treatment of onychomycosis. [Kor J Med Mycol 3(1): 115∼124]
Alu-Derived Old World Monkeys Exonization Event and Experimental Validation of the LEPR Gene
Huh, Jae-Won,Kim, Young-Hyun,Kim, Dae-Soo,Park, Sang-Je,Lee, Sang-Rae,Kim, Sang-Hyun,Kim, Ek-Yune,Kim, Sun-Uk,Kim, Myeong-Su,Kim, Heui-Soo,Chang, Kyu-Tae Korean Society for Molecular and Cellular Biology 2010 Molecules and cells Vol.30 No.3
The leptin receptor (LEPR) is a crucial regulatory protein that interacts with Leptin. In our analysis of LEPR, novel AluJb-derived alternative transcripts were identified in the genome of the rhesus monkey. In order to investigate the occurrence of AluJb-derived alternative transcripts and the mechanism underlying exonization events, we conducted analyses using a number of primate genomic DNAs and adipose RNAs of tissue and primary cells derived from the crab-eating monkey. Our results demonstrate that the AluJb element has been integrated into our common ancestor genome prior to the divergence of simians and prosimians. The lineage-specific exonization event of the LEPR gene in chimpanzees, orangutans, and Old World monkeys appear to have been accomplished via transition mutations of the 5' splicing site (second position of C to T). However, in New World monkeys and prosimians, the AluJb-related LEPR transcript should be silenced by the additional transversion mutation (fourth position of T to G). The AluJb-related transcript of human LEPR should also be silenced by a mutation of the 5' splicing site (first position of G to A) and the insertion of one nucleotide sequence (minus fourth position of A). Our data suggests that lineage-specific exonization events should be determined by the combination event of the formation of splicing sites and protection against site-specific mutation pressures. These evolutionary mechanisms could be major sources for primate diversification.
Kim, Uk Su,Park, Jeong Woo American Scientific Publishers 2018 Journal of nanoscience and nanotechnology Vol.18 No.3
<P>A direct mechanical nanomachining, tribo-nanolithography (TNL), has been developed to fabricate micro mold on Si substrate in mechanical milling mode. An atomic force microscope (AFM) tip is replaced by a lab-made Si cantilever with a polycrystalline diamond (PCD) tool. Mechanical cutting by PCD tool enables simple fabrication of micro molds with several tens of nanometers depth. Machined cavities of the Si substrate are prepared as a master mold for additional micro molding using polydimethylsiloxane (PDMS). Micro cavities are successfully duplicated in positive patterns similar to soft lithography. Normal loads of cantilever and AFM topographical images are used to discuss micro mold and micro molding characteristics.</P>
Kim, Kyu Min,Wijerathne, Tharaka,Hur, Jin-Hoe,Kang, Uk Jung,Kim, Ihn Hyeong,Kweon, Yeong Cheon,Lee, Ah Reum,Jeong, Su Ji,Lee, Sang Kwon,Lee, Yoon Young,Sim, Bo-Woong,Lee, Jong-Hee,Baig, Chunggi,Kim, S National Academy of Sciences 2018 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.115 No.20
<P>Store-operated calcium entry (SOCE), an important mechanism of Ca2+ signaling in a wide range of cell types, is mediated by stromal interaction molecule (STIM), which senses the depletion of endoplasmic reticulum Ca2+ stores and binds and activates Orai channels in the plasma membrane. This inside-out mechanism of Ca2+ signaling raises an interesting question about the evolution of SOCE: How did these two proteins existing in different cellular compartments evolve to interact with each other? We investigated the gating mechanism of Caenorhabditis elegans Orai channels. Our analysis revealed a mechanism of Orai gating by STIM binding to the intracellular 2-3 loop of Orai in C. elegans that is radically different from Orai gating by STIM binding to the N and C termini of Orai in mammals. In addition, we found that the conserved hydrophobic amino acids in the 2-3 loop of Orai1 are important for the oligomerization and gating of channels and are regulated via an intramolecular interaction mechanism mediated by the N and C termini of Orai1. This study identifies a previously unknown SOCE mechanism in C. elegans and suggests that, while the STIM-Orai interaction is conserved between invertebrates and mammals, the gating mechanism for Orai channels differs considerably.</P>
P044 : Dermoscopic findings of Tinea capitis
( Su Ran Hwang ),( Dae Woo Kim ),( Joo Ik Kim ),( Seong Min Kim ),( Jin Park ),( Seok Kweon Yun ),( Han Uk Kim ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2
Background: Dermoscopic findings of various hair and scalp disorders are available in the literatures, however the data on dermoscopic findings of tinea capitis is lacking. Objectives: The aim of this study is to determine dermoscopic findings of tinea capitis and their relations with clinical, mycological features. Methods: Dermoscopic findings of 21 tinea capitis patients who had been diagnosed with mycological study were compared with 320 healthy individuals and 329 other alopecia patients respectively. Results: Interfollicular and perifollicular scales, dirty dots, broken hairs and black dots were common dermoscopic findings of tinea captitis. Comma hair, corkscrew hair, septate hyphae-like hair, and zigzag hair were highly characteristic findings of tinea capitis which were hardly seen in control group. Among clinical subtypes, comma hairs and perifollicular pustules were more common in kerion celsi; on the other hand, broken hairs were less common in seborrheic dermatitis-like scaling types than other clinical subtypes. However, there were no significant relationship between dermoscopic findings and other clinical and mycological parameters. Conclusion: Comma hair, corkscrew hair, septate hyphae-like hairs, and zigzag hairs can be a diagnostic maker in tinea capitis. We believe that dermoscopic evaluation is a useful, non-invasive, quick method for the diagnosis of tinea capitis in order to differentiate with other alopecias.
Vibration-Assisted Electrochemical Polishing for Extremely Smooth Surface Generation
Kim, Uk Su,Park, Jeong Woo Trans Tech Publications, Ltd. 2013 Advanced materials research Vol.813 No.-
<P>This study demonstrates a novel hybrid surface polishing process combining non-traditional electrochemical polishing (ECP) with external artificial ultrasonic vibration. ECP, typical non-contact surface polishing process, has been used to improve surface quality without leaving any mechanical scratch marks formed by previous mechanical processes, which can polish work material by electrochemical dissolution between two electrodes surfaces. In recent paper, ECP using ultrasonic vibration have demonstrated surface improvement. This study verifies improved results than conventional ECP for additional experiments to vibration electrochemical polishing (VECP) using ultrasonic vibration. The localized roughness of work material is measured by atomic force microscopy (AFM) and scanning electron microscopy (SEM) for detailed information on surface. Besides roughness, overall surface quality, material removal rate (MRR), and productivity etc. are compared with conventional ECP.</P>