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가면 현상 : 비일상적인 안면 자반증 5 예 Five Cases of Unusual Facial Purpura
송은섭,원지연,정기동 대한피부과학회 2000 대한피부과학회지 Vol.38 No.7
Purpura is discoloration of the skin and mucous membranes due to extravasation of red blood cells and may be due to a variety of factors, but it is sometimes difficult to identify the exact cause. Some forms of purpura can frighten the patient and puzzle the physician. Mask phenomenon is an unusual purpura of the relatively loose tissues of the face and neck occuring after prolonged coughing, vigorous vomiting, valsalva's maneuver, parturition, or any other exertion that raises intrathoracic or abdominal pressure. This occurs with acute onset and fades within twenty-four to seventy-two hours spontaneously. A work-up for a coagulation or platelet defect is usually not required. We herein describe five cases of mask phenomenon(unusual facial purpura).
2차성 구제항암제로 Hexamethylmelamine 과 Tamoxifen에 현저히 반응을 보인, 원격장기에 전이로 재발된 난소암 1예 보고
송은섭,이우영,조숙,고승권,임영구,황성욱,이정례,김세련 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.5
저자들은 일차성 구제화학요법 후 간, 비장, 골반 및 복강내의 장기에 원격 전이 재발된 난소암 환자에서 이차성 구제화학요법으로 hexamethylmelamine과 tamoxifen을 사용하여 매우 호전을 보인 난소암 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. An advanced, recurrent epithelial ovarian cancer that had metastasized to the liver, spleen and pelvic cavity after secondary debulking surgery and first-line salvage chemotherapy, was treated with hexamethylmelamine [260 mg/m2, orally daily] and tamoxifen [20 mg orally twice daily] as a second-line salvage therapy. After 3 courses of a salvage chemotherapy, the metastatic lesions of the liver and spleen were nearly disappeared and the metastatic pelvic mass was not discovered on the abdomino-pelvic CT. This case represents our experience that hexamethylmelamine and tamoxifen can provide one of the salvage regimens to a selected patient with a advanced, metastatic ovarian cancer.