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당뇨병, 만성 신부전증 및 고혈압이 합병된 환자에서 발생한 후천성 어린선
구대원,석상미 대한피부과학회 2000 大韓皮膚科學會誌 Vol.38 No.3
Acquired ichthyosis is a rare condition and ususually occurs in adult patients with various systemic diseases and drugs that affect cholesterol metabolism. As a rule when the underlying disease goes into remission, the ichtyosis regress. Clinically and histopathologically it is similar to ichthyosis vulgaris. We report a 43-year-old man with acquired ichthyosis, who associated with diabetes mellitus, chronic renal failure and hypertension.
구대원,석상미,정승준 대한피부과학회 2000 大韓皮膚科學會誌 Vol.38 No.2
Clear cell acanthoma has been described clinically as a well circumscribed round 1-2cm sized pink to brown colored solitary nodule or plaque. It develops slowly and affects people aged 40-60 years, and the lower legs are the site of predilection. It is composed of clear cells, and reveals hyperkeratosis, parakeratosis, acanthosis, and no granular layer as well as exocytosis and microabscesses of neutrophils. In the dermis, slight increase of microvasculatures and perivascular inflammatory infiltrations exist. There is just one case reported in Korea about it, and we report another case of clear cell acanthoma developed on the lateral side of the right foot of a 65-year-old woman.
구대원,석상미,신덕용 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.11
Neonatal lupus erythematosus (NLE) is a transplacentally acquired autoimmune disorder, which is characterized by cutaneous lesions and/or congenital heart block and less commonly hepatic and hematologic abnormalities. Affected infants acquire anti-SSA / Ro antibody, anti-SSB / La antibody or less commonly anti-U1RNP antibody transplacentally from maternal circulation and it is generally thought that these antibodies are pathogenic. We report a case of NLE in a 40-day-old neonate who had erythematous annular patches on his face and extremities. Serological studies were reactive for antinuclear antibody of the speckled pattern and positive for anti-SSA/Ro antibodies and anti-SSB / La antibodies in both mother and infant. Addition to these findings, his mother had complained photosensitivity and arthralgia and showed hematological abnormalities including anemia and leukopenia, so we diagnosed his mother as systemic lupus erythematosus.