상염색체우성 다낭신의 임상경과 및 합병증

이상주,이영모,이한규,최대은,박기현,이강욱,신영태 충남대학교 의학연구소 2001 충남의대잡지 Vol.28 No.2

Autosomal dominant polycystic kidney disease(ADPKD) is one of most common hereditary disorder. It is potentially fatal and the major mobilities are hypertension and renal failure. To elucidate clinical characteristics and outcomes of ADPKD, 67 ADPKD patients were analyzed retrospectively. The male to female ratio was 48 years for males and 42 years for females. The factors leading to the dignosis of ADPKD were flank or abdominal pain (46%), palpable abdominal mass (24%), incidental findings (18%), gross hematuria and headache. Urinalysis result showed hematuria (31%), proteinuria (19%), pyuria (18%). Among renal complications hypertension (67%) was the most common. Other complications were urolithiasis (16%) upper urinary tract infection (9%), cyst infection (7%). Azotemia was observed in 24% of cases. Echocardiography showed left ventricular hypertrophy in 24% and valvular regurgitation in 18% of cases, but there was no mital valve prolapse. Cerebrovascular events occurred in 6 cases (2 cases of intervertebral hemorrhage and 4 cases of cerebral infarction). Hipatic cyst were observed in 64% of cases. Eighteen cases culminated in end stage renal failure (ESRF) at an of 47. According to this study, the most common complications of ADPKD was hypertension (67%), ESRF (27%), and cerebrovascular event (9%). Hypertension was more frequently observed in increased creatinine group than normal.

무증상 당뇨병성 말초신경병증 환자의 H반사 검사

이종걸,이상수,이태연,박계연,이성현,한설희 대한신경과학회 1999 대한신경과학회지 Vol.17 No.5

Adamkiewicz 동맥의 폐색에 의한 척수경색 1례

이광훈,이종걸,이태연,신동익,이성현,이상수,한설희,차상훈 대한신경과학회 1998 대한신경과학회지 Vol.16 No.4

혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

Mossbauer 분광법에 의한 Fe₂SiO₄의 연구

이성호,김웅태,채광표,정덕조 建國大學校基礎科學硏究所 1988 理學論集 Vol.13 No.-

Fe₂SiO₄에 관한 X-선 회절실험과 Mossbauer 분광실험을 하였다. X-선 회절실험 결과 본 시료는 olivine group에 속하는 fayalite로서 orthorhombic 구조(??)임을 알 수 있었다. Mossbauer 분광실험은 60K-834K의 온도구간에서 행하여 졌으며, Mossbaure 스펙트럼을 분석한 결과 철은 high spin 2+ 상태임을 알 수 있었고, X-선 회절실험 결과와는 다르게 철이 산소 이온들과 함께 일그러진 octahedron을 형성하고 있음을 알 수 있었다. The Fe₂SiO₄ has been studied by means of X-ray diffractometry and Mossbauer spectroscopy. The analysis of X-ray diffraction pattern shows that Fe₂SiO₄is fayalite of orthorhombic structure(??). The Mossbauer spectra which have been taken between 60K and 834K show that the valence state of iron is ferrous and high spin state and that the iron ions occupy sites of distorted octahedron whereas the X-ray analysis shows it is at a site of regular one.

프로 축구선수의 손상 분석

이경태,송백용,양기원,김나민,김장렬,박성률 대한스포츠의학회 2000 대한스포츠의학회지 Vol.18 No.2

Purpose : We evaluated and analyze the injury of the professional soccer player which would be helpful data for prevention of injury. Materials and Methods : Thirty-four professional soccer players were followed prospectively for one year and obtained injury exposure rate. We divided the injuries according to the position of the players incurred average 10 injuries for one year and the injury exposure rate was 2.9/1000hours, mostly strains and sprains of the lowre extremities. According to the player's position, the injured area and injury mechanism were different, Defence-Fielder and Mid-Fielder were more vulnerable to injury, 43% and 41.8% respectively, and mainly thigh and ankle injury. But Forward injury was less frequent and mainly leg and knee injury. In Goal-Keeper, neck and upper extremity injury was pre-dominant. Acute traumatic injury was 93% and recovery time was average on day, however, chronic overuse injury was less frequent but much longer time was required for recovery. Conclusion : The overuse injury is preventable by improving the environment and training program so that more attention is required.

대화식 시각화 접근법을 이용한 파스칼 삼각형의 탐구

이순주,송태성 부산대학교 사범대학 과학교육연구소 2007 科學敎育硏究報 Vol.34 No.-

The Pascal's Triangle has many numerical and geometrical patterns at connect other mathematical concepts. There are various interactive Java Applets of Pascal's Triangle available on the Internet. The purpose of this work is to create Flash versions of those Pascal's Triangle Java Applets. We create various interactive Pascal's Triangle Movies using Adobe Flash drawing API that provide the opportunity for students to easily explore various patterns contained in those movies. This work also provides material to help teachers lead class using Pascal's Triangle Movies. More precisely, we create movies constructing the Pascal's Triangle, natural numbers movies, triangular numbers movies, square numbers movies, pentagonal numbers movies, Fibonacci numbers movies, Catalan numbers movies, Hockey Stick pattern movies, application movies to combinatorics, application movies to binomial theorem, movies generating multiples of an integer, modular Pascal Triangle movies, and Sierpinski Triangle movies.

백서의 우울모형에서의 칼슘통로 길항제 에타베린(Ethaverine)의 항우울효과

이상경,김선희,김록우,윤성환,김용관,김경태,김영훈 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2

연구목적: 본 전임상연구에서는 우울증의 두가지 동물모형을 통해 에타베린이 단독 혹은 이미프라민과 병용처치 되었을 때의 효과를 알아보고자 하였다. 방법: 표준화된 검사법인 강제수영검사를 사용하여 옹성백서에게 에타베린(20mg/kg) 및 이미프라민 (20mg/kg)을 단독 혹은 병용 처치하였을 때의 부동시간의 변화를 관찰하였고, 경도의 만성 스트레스를 3주간 가한 후 4주간 에타베린과 이미프라민을 단독 혹은 병용 처치하였을때의 자당섭취량의 변화를 관찰하였다. 결과: 약물을 1회 단기처치 및 7일간 장기처치한 강제수영검사에서 이미프라민 및 에타베린 단독처치는 대조군에 비하여 부동시간의 단축을 보였고 에타베린은 이미프라민의 부동시간 감소에 대한 증강작용을보였다. 경도의 만성스트레스 실험에서도 3주간의 스트레스로 인하여 감소된 백서의 자당섭취량을 이미 프라민 및 에타베린이 회복시켰으며, 치료초기에 두 약물의 병용처치효과가 두드러졌다. 결론: 본 연구의 결과는 에타베린이 향우울 효과를 가지고 있음을 시사하며, 삼환계 항우울제인 이미프라민의 항우울효과를 증강시키므로 에타베린의 임상적 활용 가능성을 보여준다. Objectives: This pre-clinical study was performed to assess the effects of ethaverine in the two kinds of behavioral models of depression in rats. Methods: We observed the changes of the immobility time in the froced swimming test and the quantity of sucrose consumed in the chronic mild stress model, using ethaverine(20mg/kg) alone, imipramine(20mg/kg) alone, or ethaverine and imipramine concomitantly. Results: In the forced swimming test, both single treatment and chronic treatment(for 7days) with imipramine or ethaverine significantly reduced the immobility time, and concomitant chronic treatment with ethaverine potentiated the effect of imipramine. In the chronic mild stress model, both imipramine and ethaverine reversed the decreased sucrose consumption induced by 3-week stress and concomitantly treated ethaverine potentiated the effect of imi-pramine in the early phase of treatment. Conclusions: The data suggest that ethaverine can be used alone or concomitantly with other antidepressants in the clinical situation.

美國 超越主義者들의 自然觀 : R. W. Emerson과 H. D. Thoreau의 思想을 中心으로 based upon the ideas of R.W. Emerson and H.D.Thereau

李相五,鄭泰鎭 圓光大學校 師範大學 英語敎育學科 1983 論文集 Vol.5 No.-

The purpose of this thesis is to illucidate the American Transcendentalists' views on nature. With Emerson's Nature published in 1836 and Thoreau's major works American Transcendentalists could draw up the common denominator of their ideas. For them nature means the Creator's expression, by which they could listen to His voice. Idealism is an essential proposition to the American Transcendentalists, because this system of thought enabled them to seek for the correspondency between the idea and the matter. Defining Transcendentalism in a single word as Idealism, Emerson drew a contrast between Understanding and Reason. He insisted that the mind operating in the sphere of the experience of the senses is the Understanding, while the mind operating in the sphere of the intuitive is the Reason. According to him and other Transcendentalists, nature shows us God's presence in her phenomena by training our Reason. Thoreau was deeply interested in the details of natural facts, so that he could not translate nature into God as systematically as Emerson. But Thoreau always believed that to recognize one's relation with nature is the basis to find oneself and to identify oneself with God. And he was convinced that the obstacles to this knowledge and identification were removed by the simplification of life. Emerson has contributed to the vertical depth of the human beings in that he sought for his soul through nature, and Thoreau has contributed to the horizontal width of the human beings in that he sought for his self through nature. But they have the same opinion that the study of nature should be the prerequisite for the study of human nature.

상부요로계감염 환자에서 Gallium-67 Citrate 스캔 및 Tc-99m Dimercaptosuccinic Acid(DMSA)스캔의 임상적 의의

이강욱,강민규,장윤경,양종오,이상주,박기현,소영,신영태 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.2

It is often not certain whether the focal defect of renal cortex of Tc-99m Dimercaptosuccinic acid(DMSA) renal scan in patients with acute pyelonephritis means the cortical scar by previous inflammation or recent active inflammatory lesion. Gallium-67 citrate(Ga-67) also has been known to be accumulated at the active inflammatory lesion. In order to evaluate the usefulness of the Ga67 and Tc-99m DMSA renal scan in patients with acute pyelonephritis, we reviewed the results of both study and clinical findings. Nintecn patients with typical clinical findings of acute pyelonephritis and admitted to our institute from Jan. 1998 to Nov. 1998 were included in this study. Tc-99m DMSA and Ga-67 scan were performed mean 3.3 and 7.3 days after admission. Eleven of 19 patients (57.9%) showed abnormally increased focal renal uptake on the Gallium-67 citrate scan and 14 of 19 patients(73.7%) had a cortical defect on the kidneys in Tc-99m DMSA scan. Seven(36.8%) patients had an abnormality in both study. Seven(36.8%) patients had an abnormality only in Tc-99m DMSA scan and 4 (21.1%) patients had an abnormality only in Ga-67 scan. Of 7 patients who had an abnormality on both scan, 5 patients had. an abnormality at same region in both scan and 2 patients had an abnormality at the different sites on the kidneys. With the above results, we speculate that Ga-67 scan and Tc-99m DMSA scan play a complementary role in the patients with upper urinary tract infection.