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李鍾傑 忠州大學校 1996 한국교통대학교 논문집 Vol.31 No.1
This paper developed systematically the theory of Integral Expression using and based on set, and examined the relation of equality. Introducing the four rules of arithmetic operation on the basis of set theory and examining their properties, or this paper constructed a system of integral Expression, by introducing. I hope this paper will help think logically in using the Integral Expression and grope for desirable teaching method.
이종걸,윤정민,Chun-Mei Lin,정아영,정기연,이범준,윤영원,남상윤 충북대학교 동물의학연구소 2011 Journal of Biomedical and Translational Research Vol.12 No.1
Neurotoxicity and oxidative injury induced by glutamate cause neuronal degeneration related to various central nervous system diseases. Resveratrol, a polyphenolic compound, is known to have antioxidative and anti-inflammatory effects. The aim of this study was to investigate whether resveratrol has a neuroprotective effect against glutamate-induced toxicity in cultured cortical neurons. After exposure to glutamate for 15 min, cortical neurons originated from ICR mouse fetuses on embryonic days 15-16 were then treated with resveratrol for 24 h in the post-treatment paradigm. Glutamate induced a significant reduction in cell viability, but the cell viability was significantly increased by resveratrol. Glutamate induced ROS generation and apoptotic neuronal death, but resveratrol reduced them. The mRNA expressions in antioxidant enzymes, cytoplasmic glutathione peroxidase, copper/zinc superoxide dismutase (SOD), and manganese SOD, and anti-apoptotic regulator Bcl-xL were decreased by glutamate, but resveratrol significantly increased their mRNA levels. In addition, the mRNA expressions of pro-inflammatory cytokines, interleukin-1β and tumor necosis factor-α, were increased by glutamate insult, but significantly reduced by resveratrol. These findings indicate that resveratrol are neuroprotective against glutamate-induced toxicity, suggesting a useful therapeutic application in the treatment of neurodegenerative disorders.
李鍾傑 충주대학교 1994 한국교통대학교 논문집 Vol.29 No.1
This paper developed systematically the theory of real number using axiom based on set, and examined the relation of equality. Introducing the four rules of arithmetic operation on the basis of set theory and examining their properties, this paper constructed a system of real number. I hope this paper will help think logically in using the real number and grope for desirable teaching method.