한인진 추출물의 간장보호 작용에 관한 연구

이순복,조태순,윤기욱,이종찬,이선미,심성보 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

The dose-response effect of polysaccharide extracts(PS-1) from Artemisia iwayomogi was investigated under various hepatic disease models. Silymarin, DDB and UDCA were used as reference compounds. We found that the maximal effective dose of PS-1 was 100 ㎎/㎏ b.wt. in CCl_4-induced hepatotoxicity, D-galactosamine-induced hepatitis, in ANIT-induced cholestasis and 300 ㎎/㎏ b.wt. in CCl_4-induced chronic liver disease, 30 ㎎/㎏ b.wt. in chronic bile duct ligation and chronic ethanol fatty liver. These findings suggest that PS-1 fraction protects the hepatocyte against various hepatic injuries, and this fracton might be of therapeutic value.

Special Issue of Professor Kiehwa Lee`s Retirement: Geophysical Environments of the Korean Peninsula : Articles ; Geoelectrical Structure of the Kyongsang Basin from Magnetotelluric Sounding

( Choon Ki Lee ),( Heui Soon Lee ),( Byung Doo Kwon ),( In Ky Cho ),( Seok Hoon Oh ),( Yoon Ho Song ),( Tae Jong Lee ) 대한지구물리학회 2006 지구물리 Vol.9 No.3

筋小胞體의 ATPase Kinetics에 關한 硏究

朴映淳,李承兩,朴泰水,庾基洙,李 弘,金允坤 圓光大學校 1982 論文集 Vol.16 No.2

본 연구에서는 토끼 골격근 소포체에서 분리한 근소포체의 ATPase활성에 대한 일반적 특성과 수종의 2가 양이온(??)의 영향에 관한 연구를 하였다. ATPase활성과 Ca uptake에 미치는 2가 양이온의 저해 효과와 저해기작은 Dixon plot, Lineweaver-Burk plot, Hanes-Woolf plot, Woolf-Augustinsson-Hofstee plot, Eadie-Scatchard plot, Arrhenius plot등을 이용하여 분석하였으며 그 결과는 다음과 같다. 1. 근소포체의 ATPase는 ??과 ??의 존재하에서 활성화 되어지며 ??의 농도가 4mM일 때 ??의 최적 농도는 0.1mM이었다. 2. 근소포체의 ATPase는 ??-ATPase와 (??)-ATPase로 구성되어 있고 (??) - ATPase의 활성은 ??-ATPase의 활성보다 높았다. 3. ATPase의 활성화 에너지는 약 19Kcal/mol이었다. 4. ATPase 활성에 미치는 2가 양이온은 12.5㎛과 400㎛의 범위 내에서 이온 농도가 증가됨에 따라서 활성도는 점점 감소되었다. 5. ATPase활성율 50% 저해시키는데 2가 양이온의 농도는 Ki값과 같아서 ??, ??, ?? Pd ??에 대한 각각의 농도는 10㎛, 30㎛, 130㎛ 및 350㎛이었다. 특히 ??은 저 농도에서 (12.5-100㎛)는 활성제로, 고농도에서 (200-400㎛)는 저해제로 작용하는 것 같다. 6. 2가 양이온은 ATPase의 Km에는 변화를 주지 않으나 Vmax의 저하를 일으키는 것으로 보아 비경쟁 저해제임이 판정되었다. 7. 2가 양이온은 가역적 저해제임이 판명되었다. 8. Ca 吸收能에 대한 CuCl₂의 阻害는 50~500㎛의 CuCl₂농도에서 현저히 나타났으며 이 현상은 Ca 吸收能과 ATPase 活性과 밀접한 관계를 보여주는 것이다. General properties of the ATPase and the effects of the divalent cations (??) on the total ATPase activity of the fragmented sarcoplasmic reticulum (FSR) isolated from rabbit skeletal muscle were investigated in the present resent research. The inhibitory effect of divalent cations on the FSR ATPase activity and its mechanism were analyzed by various plots such as Dixon plot, Lineweaver-Burk plot, Hanes-woolf plot, Eadie-Scatchard plot and Arrhenius plot. The results obtained were as follows: 1. The FSR ATPase is activated by ?? and ??; the optimum concentration of is 0.1 mM in the presence of 4 mM MgCl₂. 2. The FSR ATPase could be distinguished as ??-ATPase and (??)-ATPase. The activity of (??)-ATPase predomiant over that of ??-ATPase. 3. The apparent energies of activation for total ATPase was approximately 19Kcal/mole. 4. The inhibitory effects of the divalent cations on the enzyme activity increased as the concentrations of the divalent cations increased in the concentrations between 12.5 and 400㎛. 5. Concentration of 50% inhibition for each divalent cation was almost identical with the inhibition constant (ki). The Ki's were 10,30,130, and 350㎛ for ??, ??, ??, and ??, respectively. ?? seemed to be anactivator at lower concentrations and an inhibior at higher concentratios. 6. The divalent cations did not change the Km but decreased the Vmax of the FRS ATPase, suggesting that they are noncompetitive inhibitors on the FSR ATPase. 7. The divalent cations were also found to be revesible inhibitors on the FSR ATPase. 8. The inhibitory effect of CuCl₂on a uptake increased as the concentration CuCl₂increased in the range between 50㎛.

工業敎育大學 敎育改善에 관한 硏究(Ⅲ)

宋周鎬,李昌岬,洪元杓,孟琦錫,任洪彬,李廷玟,李載元,李來烈,權五憲,金振淳,李文洙 충남대학교 공업교육연구소 1982 論文集 Vol.5 No.1

This paper aims at providing a concrete plan to improve technical and vocational teacher education in the College of Industrial Education of Chungnam National University. It is intended to propose a practical four-year regular and short-term course. Also, the estimated required facilities is included in this study as well as their management. The main conclusions and recommendations are summarized as follows; 1) The numbers of students enrollment should be reduced to 220 students which is the approximate number of future demand. 2) In order to offer to the students a broader education and to cope with the increase/decrease in demand of technical and vocational teacher within a specific field, the 8 department existing at the present (Department of Architecture Engineering Education, Civil Eng. Educ., Metallurgical Eng. Educ., Mechanical Eng. .Educ., Electrical Eng. Educ., Electronic Eng. Educ., Industrial Chemistry Educ. and Industrial Technology Educ.) would be combined into 5 (Department of Construction Engineering Education, Mechanical Eng. Educ., Electrical Eng. Educ., Industrial Chemistry Educ. and Industrial Technology Educ.). 3) The short-term course program is recommened to provide additional training and education to those candidates who already have experience in technical fields to meet an occasional demand. 4) It is necessary to add the Teaching Profession Section in the administrative organization of the College.

관동맥질환에서 저밀도 지단백 입자 크기의 분포

임효영,김인숙,승기배,강동헌,전두수,장기육,박준철,이수영,홍순조,최규보 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.8

서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

폴리스틸렌 입자로 된 서스펜션의 침강속도에 관한 연구

이기종,정순균 又石大學校 1996 論文集 Vol.18 No.-

An experimental study was carried out to investigate the settling rate of polystyrene particles of different sizes in monodisperse suspensions and the effect of volume concentration and size distribution on the settling rate in binary suspensions. As a results, the slope index n (the slopes obtained from the line of logarithm of settling rate versus logarithm of voidage) increased with the particle size decreasing, which were different from Richardson-zaki experiment results. The curves of log u_c versus log ε changed radically in slope between ε (voidage)=0.9 and ε=1, as shown in the result of the experiment of Davies et al. The critical volume concentretion of particles for the interlocking of two neighboring setting interfaces in binary suspensions depended not only on the ratio of particle sizes but also on the ratio of volume concentration of particles.

全南地域 金屬鑛山 周邊 耕作土壤의 重金屬合有量 調査硏究

李仲耆,白荀基,金全禧 동신대학교 환경연구소 1997 환경연구 Vol.2 No.1

휴ㆍ폐금속광산 주변의 경작지에 대해 토양오염의 실태를 파악하고 토양오염방지 및 사후관리 대책 수립에 필요한 기초자료를 제공하기 위하여 전남지역에 분포한 금속광산지역을 대상으로 중금속함유량을 조사하였다. 시료채취 지점은 광산으로부터의 거리에 따라 Ⅰ, Ⅱ 지역으로 나누어 중금속 농도를 측정하였다 그 결과 경작지의 중금속함유량은 광산으로부터의 거리보다는 선별방법이나 금속을 추출하고 남은 선광부산물인 광재나 폐석등의 주변환경에 더 크게 의존함을 알 수 있었다. 토양오염우려기준에 비교하여 볼 때 A, D, E 광산주변의 경작지에서 Cu, As, Cd 함량이 각각 높게 함유하고 있는 것으로 나타났으나 토양오염대책기준에는 조사된 9개 광산주변 경작지 모두에서 낮게 나타났다. To know a degree of soil pollution in cultivated soil around 9 un worked metal mines located in Chonnam area, we investigated concentrationes of heavy metals depending on a distance apart from mine. From the results there were little relation between the distance and the degree of pollution. It was observed that the content of heavy metals in the areas were mainly affected by a condition of the mines such as slag refining and mining methods, etc.. Compared with apprehensive standards, it showed that Cu, As, Cd concentration of Kwangyang(chonam mine), Bosung(myoungbong mine), Naju(deokeum mine) were respectively higher then other mine. But, all investigated area contained the heavy metals lower than a counter measure standards.

重金屬이온의 除去를 위한 새로운 이온 交換樹脂製造에 關한 硏究

李學沂,金祐埴,金淳植 慶北大學校 1981 論文集 Vol.32 No.-

Crosslinked polyacrylamide was prepared from acrylamide and divinylbenzene by the radical polymerization in methanol to prepare crosslinked polyvinylamine by the Hoffmann reaction. A Crosslinked aminocarboxylic acid resin was finally prepared by the reaction of the crosslinked polyvinylamine and chloroacetic acid. Another Aminocarboxylic acid resin was also prepared to make reference to the reaction of the crosslinked polyvinylamine with chloroacetic acid. The ion exchange capacities of the crosslinked aminocarboxylic acid resin for Zn^+2, Cu^+2, Co^+2, and Ni^+2 varied with pH and proved to be relatively high with the pH range of 6-7. The order of ion exchange for heavy metal ions was Zn^+2〉Cu^+2〉Co^+2〉Ni at the above pH region.

유도 지도자의 리더십 유형이 팀 성과에 미치는 영향

이기철,이봉건,안철순 부산 외국어 대학교 2001 外大論叢 Vol.23 No.1

With high school judo athletes as subjects, this study aims to reveal the relations between leadership types they favor and those they actually perceive. This analysis of the degrees of discrepancy and satisfaction felt by the athletes led to the following conclusions: 1.Leadership score according to sexes: 1) Autocratic behavior was the highest and affirmative feedback was the lowest in male teams. 2) Social support was the greatest and instructions appeared the lowest in female teams. 2.Leadership score in male teams according to team levels: 1) In superior teams, the highest and the lowest were social support and instructions respectively. 2) In inferior teams, autocratic and democratic behavior scored the highest and the lowest marks respectively. 3.Leadership score in female teams according to team levels: 1) In high-achievement teams, the highest and the lowest were social support and positive feedback respectively. 2) In low-achievement teams, autocratic behavior and instructions scored the highest and the lowest marks respectively. 4.Leadership discrepancy and athletes' satisfaction according to sexes: 1) The male group with lower discrepancy in instractions (p<0.01) and democratic behavior (p<0.001) showed greater satisfaction. 2) The female group with lower disagreement in autocratic behavior(p<0.01) indicated higher degrees of satisfaction. 5.Leadership behavior types and athletes' satisfaction degrees according to sexes and team levels: 1) In male teams, the excellent group in instructions and democratic behavior (p<0.01) revealed more satisfaction. 2) In female teams, the outstanding group in instructions (p<0.001), democratic behavior, and autocratic behavior (p<0.01) tuned out to be more satisfied.