림프절에 발생한 모반세포 봉입체 - 2예 보고 -

송지선,노태웅,김윤미,조상호,이광길 대한병리학회 2001 Journal of Pathology and Translational Medicine Vol.35 No.3

열형광선량계에 의한 선량평가 알고리즘 개발

송명재,김희근,하정우,이태영,윤석철 대한방사선 방어학회 1992 방사선방어학회지 Vol.17 No.2

본 연구의 목적은 ANSI N13. 11-1983의 시험기준에서 제시한 개인선량계의 선량평가 시험범주를 모두 만족시킬 수 있는 선량평가 알고리즘을 개발하는데 있다. 알고리즘 개발 대상 개인선량계로는 Teledyne Isotopes사의 PB-3 열형광선량계로 하였다. 개발된 알고리즘에 대한 미국 Atlan-Tech사와의 2차례의 검증결과, 본 알고리즘은 ANSI N-13. 11-1983의 선량평가 범주를 모두 만족시키는 것으로 나타났다. The purpose of this study is to develop an algorithm of TLD dose evaluation to meet all requirements stated in ANSI N13. 11-1983. It made the PB-3 TLD of Teledyne Isotopes an object of the development. Personal dosimetry performance testings of the development algorithm have been performed twice through the Atlan-Tech, INC. in accordance with the criteria of testing described in ANSI N13. 11-1983. As a result, it is assured that the developed algorithm has complied with all requirements stated in ANSI N13-1983.

서울시내 특급호텔 한식당의 현황

윤은숙,나영아,송태희 서울保健大學 1998 論文集 Vol.18 No.1

This study was investigated to the Korean restaurant menus from eight of the first class and five of the second class hotels in Seoul, and attempted to evaluate the restaurant evaluation and cooks job satisfaction with questionnaire surveys. The results were as follows : Korean restaurants of the first class hotel was on sale classified with a large table of food (so called kjo-ja-sang), Korean tabled hotel dinner(chong-sik), a Ia carte (il-pum yori), dessert, and wine with various prices and dishes. The first class hotel sold a lot of a large tables, second class hotel merchandised many Korean tabled hate dinner, both of them served from soup and stew of low price to high class dishes, served rice drink(sik-hei) and ginger tea with dried persimmons (su choung-kwa) with dessert, and served so-ju and bop-ju with Wine. Cooks whose sex were composed of 20% of female and 80% of male, ages were 52% of 20th, most of them graduated from high school or more. They had Korean, Western. Japanese or two or more of cooking license, had engaged in cooking for 5-10 years, worked 8 hours a day, made 1,000,000-1,500,000 won in a month. Most of them were satisfied with their job, possibilities, education training, and salary, whereas they dissatisfied with a cuisine environment such as room temperature, noise, illuminations. Therefore Korean restaurants need improve their working environment. Korean restaurants of the first class hotel had job description. standard cooking recipe, and job planing, hence we know that they were managed with scientific systems. We must attempt to survey menu design of food service system, western and Chinese restaurant as well.

녹지조건에 따른 상대습도의 변화

윤용한,송태갑 建國大學校 自然科學硏究所 2002 建國自然科學硏究誌 Vol.13 No.2

This reseach sought to measure the relative humidity in the green belt on clear days aimed at indentifying the relevancy of relative humidity with landcover status and the height of forest. Based on this measurement data, it used regresssion analysis and interpreted the relevancy of the relative humdity in the green belt with the landcover ratio and with the height of woody plants. As a result, high wet areas are formed in the forest land and near the water surface, while low wet areas are formed on the paved surface and bare ground. Taking a look at the relevancy between the landcover ratio and the relative humidity, the increase in forestland and grassland is ??ective in raising the relative humidity. Also, the increase in number of trees, regarless of the height of trees, is effective in raising the relative humdity, and the efficiency is big in the order of arbores and small arbores.

자궁내 발육지연이 있는 출생체중 2,500 g 이상인 환아의 주산기 예후에 관한 연구

송태복,조명숙,하진아,윤대석,김철홍,김윤하,최영륜 全南大醫大 2004 전남의대학술지 Vol.40 No.1

독성물질의 세포사 기전 및 세포사 유발물질의 검색법 개발에 관한 연구(Ⅰ) : 독성물질로 인한 파킨슨병 모델에서의 세포사 기전 연구 Study on the cell-death mechanisms of toxin-induced parkinsonism

강태석,김종민,서경원,김영옥,김준규,오재호,이윤동,김규봉,오정자,송연정,임종준,전범석,문전옥,최광식 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

MPTP 독성물질이 도파민성 신경세포에 선택적으로 작용하여 산화성 손상에 의한 신경세포사를 일으키는 것을 이용하여 파킨슨병의 동물모델을 만들고, 이를 통해서 아폼토시스를 비롯한 포사의 기전에 대한 연구 및 너코틴의 신경세포 보호효과 여부를 판정하는 실험을 병행하고자 하였다. 파킨슨꾐의 동물모델을 MPTf 독성 물질을 이용하여 확립하였으며, MPTP(30mgag, i.p.)를 투여한 후 1, 2,3, 4, 5일째 흑질 조직을 채춰하여 tarm로 박걸하여 tyrosine hydroxylase 면역조직화학염색을 수행하여 cell countif우한 결과, control은 57.635ce11s, 1일째 친.OfDells,2일째 57.9±6cells,3일릴 없.3±죠ells, 4일째 49.0츠3cells, 5일째 39.4±Scells료 4, 3일째 뚜렷한 신경세포 수의 감소를 보였다. 신경세포사 기전 규명을 위한 아폼토시스 분걱에서는 벼PTP 투여 후 1, 2, 3, 4, 5일째 조직을 채취하여 Hoechst staining, TUNEL staining을 수곡하였는데 양성 반응을 보인 신경세포는 관찰되지 않아. 아폼토시스로 인한 세포사가 관찰되지 않았다. bIPTP 파킨슨병 동물모델에서 nicotine 보호효과 탐색에 관한 실험은 nicat푸e 0.2mgAg을 5일 퐁안 투여 후 리『fP(30mgag)를 CS7Bt/6 마은스에 복강 내주사로 nicotine과 병용 투여한 후 1, 2, 3, 4, 5일째 뇌를 적출하땄다. 신경세포사가 뚜렷이 관찰되기 시작하는 4, 5일째의 신경세포 수의 감소 정도를 20. 30% 정도 약화시키는 경향을 보였으나, nicotine 보호효과에 대한 추가 실헝이 현재 수행 중에 있다. The cause of Parkinson's disease (PD) is largely unknown. However, free radical toxicit? may plaf a role ip. the degeneration of substantia nigra, which is the Hajorfocus of pathological damages in PD. Recently, a neuroprotective effect of nicotine in PD has been suggested. Therefore, the mechanism of neurodegenerafion and protective potential o( nicotine in PD were investigated in the experimental modeB of Pll using a neurotoxin, C57BL/6mice were administered with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP, 30 mg/kg,j.p.). The degree of neurodegenerafion was determined by immunohistochemical stainiHB oftyrosine hydroxylase (TH). TH-positive cells on nigral sections were found 56.0 ±4, 57.9 ±6,52.315ce11s, 49.0±3cells, and 39,4±Scells at days 1, 2, 3, 4, 5, respectively (controls : 57.6±Scells). Hoechst and TUNEL staining showed no evidence of apoptosis. The exandnation on themice co-adrunistered with nicotine(0.2mgAg) and MPTP(30mgag) revealed a tendency ofnicotine protective effects. At days 4 and 5, the degree of TH-positive cells was decreased by20-30%, In corclusiffn, the role of apoptosis was not evidenced in this MPTP modeB of PB.The possible proteccon by nicotine should be elucidated with further studies.

상추(Lactuca sativa L.)의 ACAT 억제 Diterpenoid, Phytol : 식용 식물자원으로부터 활성물질의 탐색 Development of Biologically Active Compound from Edible Plant Sources

장태오,방면호,송명종,홍윤희,김지영,정대균,배동근,권병목,김영국,이현선,김인호,백남인 한국농화학회 2003 Applied Biological Chemistry (Appl Biol Chem) Vol.46 No.1

Fluconazole로 치유된 안면백선 1예

이병송,윤태진 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.1

저자들은 fluconozole로 치료한 T. mentagrophytes에 의한 안면백선 1예를 경험하고 이를 문헉고찰과 함께 보고한다. Fluconazole is a triazole antifungal agent with a primarily fungistatic action in vitro. Its spectrum includes dermatophyte, filamentous, dimorphic and dermaticaceous fungi and some yeast species. Fluconazole inhibits the cytochrome P-450 dependent 14-demethylase (lanosterol N-demethylase), therefore inhibiting conversion of lanosterol to ergosterol. At low concentrations there is inhibition of the enzyme 14-demethylase and ergosterol synthesis, with an elevation in the ianosterol/ergostetrol ratio. At higher concentrations there is fungicidal activity with rapid fungal membrance damage. Fluconazole may also inhibits cytochrome C perixidative and oxidative enzymes, causing an increase in intercellular peroxide generation. Furthermore, there may be inhibition of transformation of candidal yeast forms to pseudohyphae. We experienced a patient with timea faciale caused by Trichophyton mentagrophytes. He was treated with fluconazole 150mg weekly for 3 weeks. After completion of therapy, skin lesions showed complete recovery and we could not see any laboratory abnormalities or adverse reactions.

산부인과 수술에서 Cephalothin Sodium(Keflin^(�))의 예방효과에 관한 임상적 연구

김윤하,위승길,신동현,김석모,송태복,최호선 최신의학사 2000 最新醫學 Vol.43 No.11-12

직장암 수술 후 국소재발과 예후

김태윤,백무준,김성용,신응진,박내경,이문수,김창호,송옥평 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

Locally recurrent rectal cancer is a difficult clinical problem. Local recurrence following treatment for rectal cancer is a major cause of morbidity and mortality. The reported range of local recurrence rates following surgical treatment for rectal cancer has varied from 4% to 50%. We retrospectively reviewed the charts of 142 rectal cancer patients from January 1991 to December 1999. Analysis of patients factors included age, gender, type of surgery, and adjuvant therapy. Tumors were assessed for level, stage, and grade. Local recurrence and distant metastases were also documented. Variables influencing local recurrence in this group were identified and disease-free survival is determined. Of the 142 patients(74 males, 68 females; mean age 62.6 years), 137 consecutive patients operated on for rectal cancer and followed up to December 2000 (range 23-118months) were analyzed. Local recurrence rate was 18.3%. Age and sex of patients, type of surgery, location of tumor in the rectum, size, morphology and grading of the tumor were all unrelated to the event under investigation. At Cox regression, the Dukes stage and the postoperative radiotherapy were the only independent prognostic factors for local recurrence, and Dukes stage (Hazard ratio=2.89, p<0.001) and local recurrence (Hazard ratio=3.31, p<0.01) were the only independent factors associated with improved survival.