팔라디움 복합막의 제조 및 응용

남승은,이규호 한국공업화학회 2002 공업화학 Vol.13 No.3

팔라디움(Pd)계 막들은 수소에 대한 선택투과도가 매우 높아서 고온의 혼합 기체 중에서 고순도 수소기체의 분리에 효과적으로 이용되고 있으며 탈수소 반응 등과 연계되어 많은 연구가 이루어져왔다. 순수한 팔라디움 금속 막의 경우 수소를 투과하면 수소농도에 따라 α 상 이외에 β 상이 형성되어 격자 평창에 의한 뒤틀림 현상이 발생하여 부스러지기 쉬우며 이를 보완하기 위해 니켈, 구리, 은 등 다른 금속과의 합금이 반드시 요구된다. 또한 높은 수소투과 속도와 기계적 강도를 함께 유지하기 위해 복합막 형태의 팔라디움 막이 제조되며 복합막 제조시 박막의 핀홀을 최소화하고 장기적 안정성을 유지하는 것이 매우 중요한 문제이다. 이러한 팔라디움 막을 막반응기에 활용함으로써 탈수소 반응이나 수증기 개질 반응 등의 반응효율을 크게 높일 수 있다. 본고에서는 팔라디움 막의 구조 및 수소와 다른 기체투과 메카니즘, 여러 팔라디움 복합막 제조 방법 및 이에 따른 특성 그리고 이들의 응용분야에 대해 살펴보고자 한다. Palladium(Pd) and palladium alloy membranes, which are well-known nonporous membranes with high perm-slectivity of hydrogen, have been used to separate hydrogen of high purity from vatious gas mixtures. The study of these membrane systems as hydrogen separation membranes and membrane reactors has been rather extensive for the past several decades. Pd alloys with other metals such as nickel, copper and silver are preferred over pure Pd, since pure Pd is subject to the α-β phase transformation due to the adsorption of hydrogen, which changes the atom spacing in the metal lattice and becomes brittle after repeated cycles of hydrogen sorption and desorption. For high flux of hydrogen permeation together with mechanical stability, Pd membranes have been mostly composite type structure with thin coating layer over a memchanically strong porous supporting layer. Minimization of pin holes and maintenance of long term stability of thin coating layer are very important factors in the preparation of composit membranes. The reaction effeciency of de-hydrogenation and water vapor reforming reaction was improve by the membrane reactors made with these palladium membranes. In this paper the structure of palladium membranes, the transport mechanism of hydrogen and gases, the preparation and characteristics of various composite palladium membranes and their applications will be discussed.

임상증례중심 성인 전문적 심장구조술 교육과정에 대한 고찰

유은영,박승현,박규남,최세민,김세경 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Background: To describe the first experience of case-based advanced cardiac life support(ACLS) course in Korea. Methods: We have given case-based ACLS course to 13 nurses(6 emergency nurses, 4 coronary care unit nurses, 3 professors) and 17 physicians(4 emergency physicians, 12 emergency residents, 1 intern). We performed the case-based ACLS course according to 1992 American Heart Association guidelines and recommendations for advanced cardiac life support by american ACLS instructors(1 pulmonologist, 4 critical care nurses). We performed final theoretical written test and 2 times written survey (immediate and 100th day after the course) about the course. Results: On final written test, all practitioners answered at least 70% of the questions correctly. There was no significant difference between nurses and physicians(86.2±3.6 of physicians and 82.5±6.8 of nurses, p=0.06). 90% of participants considered that case-based advanced cardiac life support was acceptable. 100th day after the course, 93% of participants answered that ACLS course have been helpful on his/her job and also want retraining of ACLS course. 70% of participants considered that ideal ACLS training committee in Korea is the Korean Society of Emergency Medicine. Conclusion: Case-based ACLS course is a useful educational method for physicians and nurses in Korea. In the future, we should organize Korean resuscitation committee and then make guidelines for ACLS, and then continuously educate physicians and nurses.

수술실 손 소독제의 종류에 따른 균주 수의 변화

홍성윤,김정민,김소영,이수정,오은실,양서인,김화실,김남초 병원간호사회 2006 임상간호연구 Vol.11 No.2

Purpose: The present study purposed to compare the hand washing effect of 7.5% powidone-iodine, which is used in the operation room of C university hospital in Seoul, with that of Ethyl alcohol-CHG mixture recommended by the US Association of Operating Room Nurses (2002) and to adopt a more effective hand disinfectant. Method: In a quasi-experimental design, 48 medical staff who participated in operations during the period from November 2004 to February 2005 had hand washing using the two kinds of hand disinfectants: 7.5% povidone-iodine and the ethyl alcohol-CHG mixture. Their palms were swabbed and cultured just after hand washing and again after taking dff sterile gloves after the operation. The number of colonies from the two occasions were counted and compared. Result: The number of general bacillus increased significantly in the group using 7.5% povidone-iodine compared to that in the group using the ethyl alcohol-CHG mixture. The number of general bacillus increased signficantly in doctors compared to that in nurses. The factors affecting the increase of the number of general bacillus were disinfectants and medical personnel. The number of general bacillus was expected to increase 9.41 times with 7.5% povidone-iodine than with the ethyl alcohol-CHG mixture and 14.87 times in doctors than in nurses. Conclusion: This study shows that the ethyl alcogol-CHG mixture has a stronger hand disinfection effect than 7.5% povidone iodine. Thus we need to change the hand disinfectant used in operating rooms as soon as possible in order to minimize the infection of wounds resulting from operations.

Line Stop 運營實態에 관한 硏究

金承楠,金銀源 조선대학교 경영경제연구소 1997 經營經濟硏究 = Management and economics research Vol.20 No.1

동일한 국제예후지표(International Prognostic Index)를 나타내는 미만성 대형 B-세포 림프종에서 Bcl-2와 p16의 임상적 중요성

박상은,박수진,곽승근,박남숙,천재민,윤환중,조덕연,김삼용,김진만 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

In Korea, malignant lymphoma is a common cancer, comprising about 2.7% of all malignant neoplasm. Diffuse large B cell lymphoma is the most common lymphoma, representing about 50% of all Non-Hodgkin's lymphoma. Diffuse large B-cell lymphoma is usually considered as heterogeneous group of neoplasms rather than a single clinicopathological entity. Clinical prognostic systems, including the International Prognostic Index (IPI), although useful to assess overall prognosis, embrace patients with heterogeneous prognoses. But International Prognostic Index scoring system is not sufficiently predict the prognosis. It is likely that the prognostic assessment of patients with diffuse large B-cell lymphomamight be improved by using biological features. Bcl-2 protein and p16 protein expression is recognized as useful biologic markers predicting the prognosis of patients with diffuse large B-cell lymphoma. To determine the clinical significance and prognostic value of bcl-2 and p16 proteins expression patterns, we studied 18 patients with de novo DLBL, whose archival pathology specimen were available for immunohistochemistry studies, atChungnam National University Hospital from September 1992 to December 2000. Archival specimens from each patient were immunostained with respective antibodies for bcl-2, p16. The results are as follows; 1) The median age was 54(rage : 37-69). There were 12 male patients(66.7%) and 6 female patients(33.3%) The 'B' symptom was abscentin all patients. The stages were as follows : Ⅰ, 2 patient(11.1%), Ⅱ, 10 patient(55.6%), Ⅲ, 4patient(22.2%) and Ⅳ, 2patient(11.1%). 3 patients(16.8%) had the elevated LDH level, 14 patients(77.8%) had the normal LDH level and 1 patients(5.6%) was not identified the LDH level. 2 patients(11.1%) had the bulky disease and 16 patients(88.7%) had no bulky diease. The distribution of ECOG status were O, 2 patients(11.1%c), 1, 14patients(77.8%) and 2, 2patients(11.1%). 2) Theimmunohistochemistry results are as follows bcl-2:+,10 patients(55.6%), bcl-2:-, 8patinets(44.4%), p16:+,3 patients(16.7%), p16:-, 15patients(83.3%) 3) After a median follow UP durations of 67 months, the median survival time was 57 months with a rage of 7-100+ months. 5-years overall survival rates was 44% by Kaplan-Meier method. 4) Reduced overall survival was demonstrated in the patients who expressed bcl-2 protein(P=0.0174). 5-year overall survivial rate was 12%(bcl-2 expression) versus 88%(no bcl-2 expression) 5) Among diffuse large B-cell lymphoma patients with IPI score 0-1, reduced overall survival was demonstrated with bcl-2 expression(P=0.023). 5-year overall survival rate was 18%(bcl-2 expression group) versus 100%(no bcl-2 expressiongroup) 6) Median survival durtation of diffuse large B-cell lymphoma patients negative for p16 expression was 57 months whereas p16 postive patients' median survival duration was not reached(P=0.4478). In diffuse large B-cell lymphoma patients with identical IPI scores, bcl-2 expression had additional prognostic value.

Sheehan 증후군 발생한 Torsades de Pointes

김승환,김남호,김용철,최준호,박은미,이상재,이은미,유남진,윤경호,오석규,정진원 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.1

재발하는 심실 빈맥으로 내원한 환자에서 Sheehan 증후군을 진단하였고, 적절한 호르몬 보충 치료 후 심전도 이상이 정상으로 회복된 예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Torsades de Pointes is a form of polymorphic ventricular tachycardia that is associated with prolongation of QT intervals, characterized by QRS complexes of progressively changing ampulitude and cyclic length, giving the appearance of oscillations around the baseline. A 77 years-old woman was presented with hypotention and arrhythmia. Twenty four-hour ECG showed typical episodes of torsades de pointes with QT prolongation. This arrhythmia was controlled by isoproterenol and magnesium infusion, but it was not disappeared. She was diagnosed as Sheehan's syndrome by past history, anterior pituitary stimulation test and empty sella on CT scan. After hormone replacement treatment, Prolonged QT interval was normalized and polymorphic ventricular tachycardia has not recurred. We report a case of torsades de pointes associated with Sheehan's syndrome

거대적아구성빈혈의 임상적 고찰

곽승근,천재민,박남숙,박상은,박수진,윤환중,김삼용,조덕연 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Megaloblastic anemias are disorders caused by impaired DNA synthesis and chara-cterized by the presence of megaloblastic cells. Clinical data on these disorders in Korea are limited. The aim of this study was to analyze clinical characteristics of megaloblastic anemias caused by vitamin B12 deficiency. We identified 40 cases who were diagnosed as megaloblastic anemia from January 1993 to December 2002 in a retrospective study on the basis of chart review. We investigated the annual distribution of diagnosed patients, clinical manifestations and response to treatment. 19 cases were complicated with a previous total gastrectomy(gastrectomy group) and 21 cases had no history of surgical operation(non-gastrectomy group). The most common presenting complaint was generalized weakness. The median age at diagnosis was 7(range: 38-79) years in non-gastrectomy group. The mean pos-toperative duration was 7(range: 4-25)years in group of total gastrectomy and mean level of serum vitamin B12 was lower than 100 pg/mL in both group. Peripheral blood revealed thrombocy-topenia, macrocytic anemia and hypersegmented neutrophil in all cases. After treatment of pareliteral vitamin B12, Their clinical symptoms and hematologic findings improved except two patients who had bone marrow with lower cellularity. Cobalamin replacement after total gastrectomy is still missing. Diagnoses are made too late in a population of patients, resulting in irreversible neurological sequale, and we suggest that Pernicious anemia seems not to be very rare in Korea.

신생아 고 17α-Hydroxyprogesterone치의 추이

박은영,조진형,이수진,양승,김광남,신재훈,오필수 대한소아내분비학회 2003 Annals of Pediatirc Endocrinology & Metabolism Vol.8 No.2

초등학교 과학 수행평가에 대한 교사의 인식

서승조,조태호,백남권,박강은,김성규,박장서 晋州敎育大學校 科學敎育硏究所 2001 科學敎育硏究 Vol.27 No.-

The purposes of this study are to examine how Science Performance Assesment is being well conducted in elementary schools and to check the teachers' awareness through surveying the actual condition. To achieve this purpose, the author, in this study, distributed questionnaire developed by researcher under supervision of academic advisor to the elementary school teachers in Gyeongnam province. Based on the data. the research results were mainly analyzed by the statistical method using Chi-square test. The survey was consisted of questions which was designed to perceive teachers' awareness about elementary school science performance assessment. The main findings of this study are summarized as follows', 1. Elementary teacher's are doing affirmative estimation about induction of performance assessment. 2. Most teacher are recognizing performance assessment right and teachers' understanding appeared high. 3. Material development of performance assessment is recognizing that people who have opinion which is special must develop. 4. The biggest problem of performance assessment fixing is recognizing that number of persons per class are many and amount of training courses is much also with the tribe during time. 5. It was recognizing positively whether it is in class improvement of performance assessment effect. 6. Teachers had awareness that confirm studies accomplishment degree through performance assessment, or will utilize to improvement material of teaching-learning method.

산복도로에서 보는 釜山港 景觀의 構圖的 特徵 에 관한 硏究

심은경,강영조,김승환,남정칠,박승범,이기철,박한우 동아대학교 건설기술연구소 2000 硏究報告 Vol.24 No.1

This study is to clarify the characteristics of the type of view on a prospect from the road view, approach to the purpose of the maintenance plan of the road view. First, in the viewpoint of view is understanding meaning of the road, the method come into contact with a road view. Second, in the view appear an object land is grouping to the road view and presentation to a point in dispute and a settlement. This study have the keynote to different a form of view depend on viewpoint in a point view of prospect of road view, it will be presentation of practice method to the maintenance plan of the road view of the future.