Clinical outcome and safety of holmium laser prostate enucleation after transrectal prostate biopsies for benign prostatic hyperplasia

최세민,강창석,김대현,최재휘,이천우,제성욱,감성철,화정석,현재석 대한비뇨의학회 2024 Investigative and Clinical Urology Vol.65 No.2

Purpose: This study aimed to assess the clinical outcome and safety of holmium laser enucleation of the prostate (HoLEP) following transrectal ultrasound-guided prostate biopsy (TR biopsy) in the treatment of benign prostate hyperplasia. Materials and Methods: We retrospectively analyzed data from 556 patients who underwent HoLEP between 2014 and 2021. The patients were categorized into six groups: Group 1-A (n=45) underwent HoLEP within four months post TR biopsy. Group 1-B (n=94) underwent HoLEP more than four months post TR biopsy. Group 1-C (n=120) underwent HoLEP after a single TR biopsy. Group 1-D (n=19) underwent HoLEP after two or more TR biopsies. Group 1-total (n=139, group 1-A+group 1-B or group 1-C+group 1-D) underwent HoLEP post TR biopsy. Group 2 (control group, n=417) underwent HoLEP without prior TR biopsy. We examined perioperative parameters, safety, and functional outcomes. Results: The age, body mass index, International Prostate Symptom Score (IPSS), uroflowmetry, and comorbid diseases between group 1-total and group 2 were comparable. However, group 1-total exhibited significantly elevated prostate-specific antigen levels and larger prostate volumes (p<0.01). Perioperative factors like enucleation time, enucleation weight, and catheterization duration were notably higher in group 1-total (p<0.01). All groups showed significant improvements in IPSS, postvoid residual urine, and maximum flow rate during the 1-year postoperative period (p<0.05). The rates of postoperative complications were similar between group 1-total and group 2. Conclusions: Enucleation time and catheterization duration were significantly longer in the TR biopsy group. However, postoperative complications were not significantly different between TR biopsy and non-TR biopsy groups.

예술치료 전공 대학원생을 위한 연구윤리 교육과정 개발 및 운영방법 탐색

최세민 한국예술심리치료학회 2018 예술심리치료연구 Vol.14 No.3

본 연구는 예술치료 전공 대학원생을 위한 연구윤리 교육과정의 개발 및 운영방법을 탐색하는데 목적을 두고 있다. 연구방법은 문헌 분석, 예술치료전공 대학원생과 교수를 대상으로 한 설문 및 전문가 심층면담 등의 통합적인 방법을 활용하였다. 연구를 통해 나타난 결과를 요약 정리하면 다음과 같다. 먼저, 예술치료전공대학원생을 위한 연구윤리 교육과정 개발에 대하여 알아본 결과 첫째, 예술치료 전공대학원생과 교수 모두 연구윤리 교육과정의 필요성과 효과에 대하여 긍정적인 인식을 하고 있는 것으로 나타났다. 둘째, 연구윤리 교육의 학점 및 시수에 대하여 교수와 대학원생 모두 2학점(2시간)으로 하는 것이 가장 적정하다는 반응을 보였다. 셋째, 연구윤리교육의 목표에 대하여 교수와 대학원생 모두 정직성을 가장 중요한 목표로 인식하는 것으로 나타났다. 넷째, 연구윤리교육에서 우선적으로 다루어야 할 주제에 대하여 교수와 대학원생 모두 연구논문 작성방법이라는 응답을 하였다. 다음으로, 예술치료 전공대학원생을 위한 연구윤리교육과정의 운영과 관련하여 첫째, 연구윤리 교육과정과 졸업논문의 연계에 대해서는 교수의 경우 연계가 필요하다고 한 반면 대학원생은 연계가 불필요하다는 반응을 보였다. 둘째, 연구윤리교육과정 운영시 필수/선택에 대하여 교수와 학생 모두 필수교과로 운영하는 것이 바람직하다는 반응을 보였다. 셋째, 연구윤리 교육 수업방법에 대하여 교수와 대학원생 모두 토론식 수업에 대한 선호도가 가장 높게 나타났다. 넷째, 연구윤리 교육과정 평가 방법에 대하여 교수의 경우 학점으로 평가하는 방안을 선호하는 반면 대학원생의 경우에는 패일/패스방식을 선호하는 것으로 나타났다. This study was to develop a research ethics curriculum applicable to graduate students of arts therapy and to examine how to apply it to these students. This research took an integrated approach was taken by analyzing literatures, by conducting a survey on the selected graduate students of arts therapy and by having an in-depth interviews with the selected professional. The major findings of the study were as follows: First, the professors and the graduate students placed a high value on the necessity and importance of a research ethics curriculum. Second, as for credits for this curriculum, both of the professors and the graduate students responded that two credits would be most appropriate. Third, Both professors and graduate students recognize the goal of research ethics education as honesty. Forth, regarding the connection between research ethics education and graduation thesis, the professors considered that to be necessary, whereas the graduate students responded it's unnecessary. Fifth, concerning the operation of this curriculum, both of the professors and the students responded that it's advisable to operate it as a required course. Sixth, as for the method of evaluation, the professors preferred the evaluation by letter grade, while the graduate students had a liking for pass-fail tests. Seventh, as to the themes of this curriculum, both of the professors and the students answered that how to write a research paper should be the top priority. Eighth, in regard to the teaching method of research ethics education, discussion-based instruction was considered to be most proper.

전략훈련과 설명적 교수가 학습장애 학생의 수학문장제 문제해결능력과 학습된 무력감에 미치는 영향

최세민 한국학습장애학회 2006 학습장애연구 Vol.3 No.1

본 연구는 전략훈련(인지-초인지 전략, 자기교수전략)과 설명적 교수가 학습장애 학생의 수학문장제 문제해결 능력과 학습된 무력감에 미치는 영향을 알아보기 위해 실시되었다. 연구 대상은 서울특별시 소재 중등학교에 재학 중인 학습장애 학생 30명으로 하였으며, 연구를 통해 나타난 결과를 요약 정리하면 다음과 같다. 첫째, 전략훈련(인지-초인지 전략, 자기교수전략)은 설명적 교수방법보다 학습장애 학생의 수학문장제문제 해결능력을 증진시키는데 효과적인 것으로 나타났다. 둘째, 전략훈련(인지-초인지 전략, 자기교수전략)의 효과는 학습과제의 특성에 따라 차이가 있는 것으로 나타났다. 즉 단순과제의 경우 두 방법 모두 설명적 교수방법 보다 효과적이었으나 복합과제의 경우 인지-초인지 전략훈련은 설명적 교수방법보다 효과적이었으나 자기교수전략훈련은 설명적 교수방법과 차이가 없었다. 셋째, 전략훈련(인지-초인지전략, 자기교수전략)은 설명적 교수방법보다 학습과제의 유지에 효과적이었으나, 유지효과 또한 과제의 특성에 따라 다르게 나타났다. 즉 단순과제의 경우 두 전략훈련 모두 설명적 교수방법에 비해 유지 효과가 있는 것으로 나타났으나, 복합과제의 경우에는 인지-초인지 전략훈련은 설명적 교수방법보다 유지에 효과적이었으나 자기교수전략훈련은 설명적 교수방법과 차이가 없었다. 넷째, 전략훈련(인지-초인지 전략훈련, 자기교수전략훈련)은 설명적 교수방법보다 학습장애 학생의 학습된 무력감을 감소시키는데 효과적인 것으로 나타났다.

구조화된 악기중심 음악활동이 발달지체 유아의 사회적 상호작용과 반사회적 행동에 미친 효과

최세민 한국예술치료학회 2016 한국예술치료학회지 Vol.16 No.1

본 연구는 구조화된 악기중심 음악활동이 발달지체 유아의 사회적 상호작용중진과 반사회적 행동 감소에 미치는 효과를 알아본 것이다. 연구대상은 일반 유아교육기관에 통합된 발달지체 유아 2명과 같은 반 또래 유아들이었다. 연구 설계는 중다기초선 설계를 사용하였다. 먼저, 중재를 실시하기 전 발달지체 유아 2명의 기초선을 설정하고, 자유놀이 시간에 구조화된 악기중심 음악 활동을 실시한 다음 발달지체유아의 사회적 상호작용행동과 반사회적 행동의 변화를 관찰 하였다. 이러한 절차와 방법을 통해 얻어진 결과를 요약 정리하면 다음과 같다. 첫째, 구조화된 악기중심 음악 활동은 발달지체유아의 사회적 상호작용 행동을 증진시키는데 효과가 있었다. 기초선 에서는 발달지체 유아의 또래 상호작용이 거의 관찰 되지 않았으나, 중재 이후에는 안내하기, 언어로 묻기, 놀잇감 나누어 갖기, 놀이참여하기 등과 같은 행동이 점진적으로 증가하였다. 둘째, 구조화된 악기중심 음악 활동은 발달지체 유아의 반사회적 행동을 감소시키는데 효과가 있었다. 기초선에 비해 발달지체 유아의 언어적 공격, 신체적 공격 그리고 위협행동 등이 점진적으로 감소하였다. 또한, 실험 종료 1주 후에 실시한 유지검사에서도 사회적 상호작용 행동과 반사회적 행동 모두 일정수준으로 유지되었다. The purpose of this study was to examine the effects of music activities by structured musical instruments on the social interactions and antisocial behaviors of preschoolers with developmental delay. The subjects in this study were two selected preschoolers with developmental delay and their peer classmates. The preschoolers with developmental delay attended a regular early childhood education institution. As for research design, multiple baseline design was adopted. Before the intervention was provided, baseline for the young children for developmental delay was selected, and then music activities were conducted using structured instruments in free-play sessions. And then the young children with developmental delay were observed to measure their social interaction behaviors and antisocial behaviors. The major findings of the study were as follows: First, the music activities by structured instruments were effective at increasing the social interaction behaviors of the preschoolers with developmental delay. In the baseline period, they had little interactions with their peers while they were observed. After the intervention was provided, however, there was a gradual increase in their behaviors such as giving information, asking questions in language, sharing toys or joining others for play. Second, the music activities by structured instruments was effective at relieving the antisocial behaviors of the young children with developmental delay. There was a gradual decrease in verbal aggression, physical aggression and threatening behavior in comparison with what they did in the baseline period. When a retention test was carried out a week after the experiment, they continued to show more social interaction behaviors and fewer antisocial behaviors than in the baseline period as well.

인지-사회적 역할놀이 활도이 발달지체 유아의 사회적 기술과 사회적 상호작용에 미치는 효과

최세민 公州大學校 特殊敎育硏究所 1999 특수교육논집 Vol.4 No.1

The purpose of this study was finding effects of social-cognitive role play activity and free play activity on developmentally delayed young children and peers' interaction. In order to achieve this purpose, developmentally delayed young children and norm리 young children were asked to acquire the social skill concepts through role play and free play activity using the constructive puppet performance and to use these concept through role play and feedback. Also, it is suggested that the social skills acquired by developmentally delayed young children are used by normal young children together. This study focuses on 20 developmentally delayed preschoolers and 18 normal young children in integrated classroom of nursery school in Seoul. From each the group, young children were chosen tentatively into the cognitive-role play group and free play group. Here again, the role play group were divided into high level and low level according to the personal verbal communication skill. The results of this study are the following. 1. A cognitive-role play in comparison with a free play had an effect on improving the peer acceptance of developmentally delayed young children. 2. A cognitive-social role play in comparison with a free play had an effect on improving social competence and school adjustment behavior of developmentally delayed young children. 3. A cognitive-role play in comparison with a free play had a partial effect on reducing maladjustment behavior scale of developmentally delayed young children. Such results may be derived in some views as follows. First, the result of comparison and analysis for subject' individual scores for a maladjustment behavior showed that most of them got a score close to 0 in sub-realms, accordingly it is considered as the influence of floor effect. Second, a cognitive-social role play is composed based on contents' to rise social skills of developmentally delayed young children, therefore this study have a limit to reduce problematic behaviors like aggressive behaviors or rebellious behaviors included into a maladjustment behavior scale. Third, in case of developmentally delayed young children, when they try to approach and react peers, they excessively contact physically because of their poor verbal communications. 4. A cognitive-social role play in comparison with a free play had an effect on improving social interactions of developmentally delayed young children and normal young children. Social interactions of developmentally delayed young children were examined by sub-realms. The result showed that they had an effect on the initiation and affirmative responses of interactions and expended social interactions. A negative response for peer initiations was also reduced. A more minute analysis of this results showed that a start behavior and an entry behavior were improved, and an affirmative response and an alternative response were improved. An in expanded social interaction, a question behavior out of sub-realms was improved. These results showed that developmentally delayed young children more positively started interactions to young children and affirmatively responsed on initiations of peers. In addition, a cognitive social role play in comparison with a free play had an effect on increasing social interaction times of developmentally delayed young children. That is why social interactions of developmentally delay young children got more actively proceed by the improvement of their social skills, and they could more continuously interact with peers one play This means that social interaction pattern of developmentally delayed young children are continuously changing not one time, and a cognitive-social role play has qualitatively changed an interaction pattern of developmentally delayed young children. Besides, social interactions differently indicated according to a verbal ability of developmentally delayed young children, this means that a high verbal ability made social interactions more actively performed. And a social skill(adaptive behavior) learned by a cognitive-social role play had an effect of maintenance.

특수학교 직업지도 현황과 문제점 및 개선 방안에 관한 연구

최세민,김주영 한국진로교육학회 2006 진로교육연구 Vol.19 No.2

The purpose of this study was to examine how vocational education was provided to student with disabilities, what problems it was faced with and what reform measures there would be. After literature of vocational education intended for student with disabilities was reviewed, teachers who were in charge of vocational education for student with disabilities were interviewed to acquire qualitative data on special schools. In addition, experts had a conference about ideal directions for vocational education. After problems with occupational education for student with disabilities and feasible reform measures were discussed, the following findings were given:There were several problems with vocational education provided by special schools to student with disabilities, such as uniform education, a shortage of qualified professional teachers, emphasis of school convenience, a lack of relevant facilities and insufficient opportunities for occupational exploration. There was something wrong with school-to-work in special schools as well, like a lack of identity and inadequate opportunities for professional job education. Besides, student with disabilities' diverse needs weren't satisfied.To tackle those problems, a wide variety of measures should be taken to enrich vocational education to help special schools provide quality vocational education. It's also needed to take actions to improve school- to-work and vocational education in special classes, and there should be legal and institutional aids to remedy the current situations.

원예치료 활동이 고등학교 특수학급학생의 적응행동과 정서에 미친 영향

최세민 국립특수교육원 2001 특수교육 사례연구 Vol.2 No.-

Metabolic effects of androgen deprivation therapy

최세민,감성철 대한비뇨의학회 2015 Investigative and Clinical Urology Vol.56 No.1

The therapeutic effects and side effects of androgen deprivation therapy (ADT), which is a main treatment method for metastaticprostate cancer, are well known, but the metabolic effects have only recently been studied. This review describes the effects of ADTon body habitus, insulin resistance, lipid profiles, diabetes, metabolic syndrome, and cardiovascular morbidity and mortality. Thereview was done by using KoreaMed and PubMed to search the medical literature related to prostate cancer, ADT, body habitus,lipid profile, diabetes, insulin resistance, metabolic syndrome, and cardiovascular disease. ADT increases fat mass and decreaseslean body mass. Fat mostly accumulates in the subcutaneous area. ADT increases total cholesterol, triglycerides, and high-densitylipoprotein, as well as the risk for insulin resistance and diabetes. ADT also increases the risk for cardiovascular events, but insufficientevidence is available for a correlation with mortality. ADT changes body habitus and lipid profiles and has different characteristicsthan those of classic metabolic syndrome, but it is related to insulin resistance and diabetes. ADT increases the risk forcardiovascular events. No consistent guidelines have been proposed for treating the metabolic effects of ADT, but the generallyrecommended treatment methods for lowering the risk of diabetes and cardiovascular disease should be fully understood. Additionalstudies are necessary.

특수교육지원센터 서비스 질 결정 요인 분석

최세민 이화여자대학교 특수교육연구소 2012 특수교육 Vol.11 No.3

본 연구는 특수교육지원센터의 서비스 질 결정요인을 알아보기 위하여 실시된 것이다. 연구대상은 전국 특수교육지원센터 근무자 166명으로 하였다. 이들을 대상으로 설문을 실시하여 특수교육지원센터의 서비스 질 결정요인을 알아보았다. 본 연구를 통하여 나타난 결과를 요약 정리하면 다음과 같다. 첫째, 특수교육지원센터의 서비스 질에 대한 지각은 성별, 고용형태, 그리고 지역에 따라 유의한 차이가 나타났다. 즉, 남성이 여성에 비해, 정규직이 비정규직에 비해, 그리고 농·산·어촌이 대도시에 비해 높게 나타났다. 둘째, 특수교육지원센터 근무자의 서비스 질과 관련하여 직무관련 요인에서는 직무태도와 전문성을 가장 높게 평가하고 있으며, 반면 직무프로세스와 직무환경요인은 상대적으로 낮게 평가하고 있는 것으로 나타났다. 셋째, 특수교육지원센터 근무자의 만족에서는 센터 만족과 직무만족이 비교적 낮게 나타났다. 즉, 근무자의 전반적 만족도는 낮다고 볼 수 있다. 넷째, 센터의 업무프로세스와 서비스 질 관리 및 지원센터 환경만족 또한 매우 낮은 것으로 나타났다. 다섯째, 지원센터 근무자의 센터 지원만족과 직무만족에 영향을 미치는 요인을 알아본 결과 직무태도와 직무전문성이 가장 높은 상관을 보였으며 센터지원만족은 다른 요인들과 가장 밀접한 관련이 있는 것으로 나타났다. The purpose of this study was to examine the determinants of the quality of service provided by employees of special education support centers. The participants in this study were 166 people who included teachers of special education support centers across the nation and experts in this field. A survey was conducted by visiting the selected people to determine what factors would affect the quality of service provided by the special education support centers. As for the data of the survey, a statistical analysis was conducted to look into the determinants of the quality of service and the factors related to their satisfaction with support from the centers. The findings of the study showed that when each of the determinants of the quality of service was analyzed, job attitude and professionalism were found to be major factors to affect the quality of service among the job-related factors. In contrast, the factors of job process and job environments were found to exert a relatively less influence on that. The employees of the special education support centers expressed relatively lower satisfaction with the centers and their job. In other words, it could be said that the overall satisfaction of the employees was low. There were significant differences in satisfaction with work process and environments according to the type of employment and gender. In terms of the type of employment, the regular workers were more satisfied than the irregular workers. By gender, the male employees were relatively more satisfied than the female employees. An analysis of factors that affected the satisfaction of the employees with support from the centers and their job satisfaction indicated that job attitude and job professionalism had the closest correlation to job satisfaction and the other factors were most closely correlated to satisfaction with support from the centers.

코코아 추출물의 흰쥐 음경 해면체 이완에 미치는 영향

최세민,서덕하,이승현,제성욱,감성철,정재훈,화정석,정기현,현재석 대한남성과학회 2008 The World Journal of Men's Health Vol.26 No.3

Purpose: Cocoa has antihypertensive activity, improves cerebral blood flow, and is an antioxidant. We evaluated the effect of cocoa extract on penile erection using the relaxation of the corpus cavernosal tissue in rat. Materials and methods: We used male 8-week-old Sprague-Dawley rats weighting 250-350 g divided into three groups: corpus cavernosal tissue with the endothelium (group 1), tissue without the endothelium (group 2), and endothelium pretreated with L-NAME (group 3). Changes in isometric tension were examined in an organ bath. Aortic tissues were divided into three groups and treated in similar experiments simultaneously. Results: Cocoa extract dose-dependently relaxed corpus cavernosal tissue pre-contracted by phenylephrine (10-6). In group 1, cocoa extract (10-3g/ml) induced relaxation by 97±5% (mean±SD). The extract was still effective but less potent tissue without endothelium or pretreated with L-NAME (10-4M). Similar effects were seen in aortic rings. Conclusion: Cocoa extract relaxes corpus cavernosal tissue in a dose-dependent manner via NOS and the endothelium. Cocoa extract may therefore be effective for improving erectile function.