40세 이하 관상동맥 질환자에서 장기적 임상 관찰

이승욱,정명호,박종철,박형욱,조상희,김원,김계훈,이상현,강경태,조장현,김남호,김건형,안영근,조정관,박종춘,강정채 全南大醫大 2001 전남의대학술지 Vol.37 No.2

다중 제어루프에 의한 자기부상용 DC-DC 전원장치에 관한 연구

조주현,조정민,전기영,이상집,이승환,오봉환,이훈구,한경희 明知大學校 産業技術硏究所 2004 産業技術硏究所論文集 Vol.23 No.-

The author present a modified multi-loop algorithm including feedforward for controlling a 55kW step down chopper in the power supply of Maglev. The control law for the duty cycle consists of three terms. The first is the feedforward term which compensates for variations in the input voltage. The second term consists of the difference between the slowly moving inductor current and output current. The third term consists of proportional and integral terms involving the perturbation in the output voltage. This perturvation is derived by subtracting the desired output voltage from the actual output voltage. The proportional and integral action stabilizes the system and minimizes output voltage error. In order to verify the validity of the proposed multi-loop controller, simulation study was tried using Matlab simulink.

여성 복압성요실금 환자에서 안정 시 방광조영술상 Inverted Tear-drop Sign의 의의

오승준,문경현,주명수,조경식 大韓泌尿器科學會 2001 Korean Journal of Urology Vol.42 No.4

Step test시 승강대 높이에 따른 타당도 연구

조현철,신승윤 龍仁大學校 體育科學硏究所 1998 體育科學硏究論叢 Vol.8 No.1

The purpose of this study was to verify validity of height of step test that is selected for estimation of endurance in college entrance examination. A total of 24 college male student subjects were performed two different bench heights(40cm, 50.8cm) in 30 stepping/min for 5minutes and measured heart rate during stepping and recovery and cadio-pulmonary endurance capacity using Bruce protocol. The results were obtained as follow : 1. It was showed generally lower correlation between heart rate and maximum oxygen consumption. 2. Both of 3minutes and 5minutes step test can be selected there higher correlations between recovery heart rate of in 40cm height and both of stepping time(3minutes and 5minutes). However, there were lower correlations between recovery heart rate of in 50cm height. 3. It was showed that 40cm step height was more effective then 50cm step height according to correlation between VO2max and step heights According to the results, it is considered that it is necessery to introduce new estimation method and the step height adjustment method for effective estimation of endurance capacity.

잠김 금속판을 이용한 대퇴골 전자하 골절의 치료 : 압박 고 나사와 비교

손현철, 김용민, 김동수, 최의성, 박경진, 조병기, 박지강, 배승환 충북대학교 의과대학 충북대학교 의학연구소 2011 忠北醫大學術誌 Vol.21 No.2

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Helicobacter pylori와 대장균의 Shuttle Vector 개발

조명제,이우곤,이상룡,김경희,안영숙,김성희,김현주,류복덕,최여정,윤영혜,백승철,전영석,이광호 경상대학교 유전공학연구소 1997 遺傳工學硏究所報 Vol.16 No.-

In this study, a vehicle vector using cryptic plasmids was constructed for gene transfer in Helicobacter pylori. pHP51(3.9 kb) and pHP489(1.2 kb) were selected for constructing vectors from cryptic plasmid of H. pylori isolates in Korea. The HindⅢ-digestedDNA fragment(1.2kb) of pHP489 and 1.6kb DNA fragment of pHP51 were ligated with a kanamycin resistance gene(aph3'-Ⅲ) from C. jejuni to produce the recombinant plasmids pHP489K and pHP51K, respectively. Transformation frequency of pHP51K by electroporation was low. But pHP489K could be effectively transformed into various H. pylori strains. In order to design an intermdiate vehicle vector for gene transfer into H. pylori, pBlueHP489K was prepared by recloning pHP489K DNA into pBluescript and pTZ19R vector. This vector permitted the DNA fragment containing pHP489 sequence, aph3'-Ⅲ, and cloned DNA to be cut and self-ligated in the SacⅠ site after cloning. ureA and ureB gene were inserted into pBlueHP489K, resulting in pBlueHP489K/AB. The DNA fragment containing pHP489, kanamycin resistance gene(aph3'-Ⅲ), and urease structural gene was cut away from pBlueHP489K/AB and self-ligated to generate pBlueHP489K/AB. pBlueHP489K/AB made urease-negative H. pylori strains restore their urease activity. By this experiment, pBlueHP489K was confirmed to be the vehicle system for transferring H. pylori genes.

新興家內工業의 地域形成과 存立形態 : 全南 海南郡 黃山面 옥연의 옥돌工藝業을 中心으로 Hwangsan-myeon, Haenam-gun, Chonnam Province

曺勝鉉 全南大學校 人文科學硏究所 1985 용봉인문논총 Vol.15 No.-

The purpose of this thesis is to investigate how agalmatolite-product domestic industry has grown in Ockyeon village. Through this case study, it is hoped that we can shed some light on the origin and formation process of Korean traditional handicraft industry. The primary data for the present study were collected by utilizing interview schedule. In addition, informal interviews were held to all producers. The study results can be summarized as the followings : 1) The agalmatolite-product industry in this area was originated from a village which is located 10km away from Ockyeon village, in 1930s. But one of the producers migrated to Ockyeon village in 1959. After this happened, the village had become a new center of the industry. The major reason for this relocation- diffusion was that it was much easier to acquire the material, i.e., agalmatolite, in Ockyeon village than in the original village. It is noted that the industry is material-oriented one in its nature. 2) The development of the industry can be marked by two phases : the first phase covers 1959 ~ 1969 time period, and the second phase falls into 1970 ~ 1985 time period. The first phase refers to the period when the products were made through handicraft. The second phase characterized by the use of machines in its production. During this phase, the products became more diverse, and production level increased. 3) The industry is not specialized in terms of production and merchandizing. With respect to specialization, it is also noted that about half of the producers have additional jobs.

비유피-4 정(염산프로피베린 20㎎)에 대한 건일염산프로피베린 정의 생물학적동등성

조혜영,박은자,강현아,백승희,김세미,박찬호,오인준,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.5

The purpose of the present study was to evaluate the bioequivalence of two propiverine hydrochloride tablets. BUP-4 (Jeil Pharm. Co., Ltd.) and Kuhnil Propiverine Hydrochloride (Kuhnil Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The propiverine release from the two propiverine hydrochloride formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with a variety of dissolution media (pH 1.2, 4.0, 6.8 buffer solutions, water and blend of polysorbate 80 into pH 6.8). Twenty six healthy male subjects, 23.73 ± 2.79 years in age and 67.04 ± 7.93 kg in body weight, were divided into two groups and a randomized 2 x 2 cross-over study was employed. After one tablet containing 20 mg as propiverine hydrochloride was orally administered, blood was taken at predetermined time intervals and the concentrations of propiverine in serum were determined using HPLC method with UV detector. The dis-solution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC" C _(max) and T _(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC, C_(max), and untransformed T_(max). The results showed that the differences between two formulations based on the BUP-4 were 0.17%, 7.98% and 4.55% for AUC,, C_(max), and respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically trans-formed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.88)-log(l .12) and log(0.90)-log(l.15) for AUC, and _(max), respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Kuhnil Propiverine Hydrochloride tablet was bioequivalent to BUP-4 tablet.

아마릴 정(글리메피리드 2㎎)에 대한 글리메드 정의 생물학적 동등성

조혜영,박은자,강현아,백승희,이석,김세미,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.2

The purpose of the present study was to evaluate the bioequivalence of two glimepiride tables, Amaryl^(?)(Handok/Aventis Pharm. Co., Ltd.) and Glimed (Kuhn Ⅱ Pharm. Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). The glimepiride release from the two glimepiride formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with a variety of dissolution media (pH 1.2, 4.0, 6.8 buffer solution, water and blend of PSB 80 into each dissolution medium). Twenty six healthy male subjects, 22.65±2.19 years in age and 66.55±8.85 kg in body weight, were divided into two groups and randomized 2×2 cross-over study was employed. After one tablet containing 2 ㎎ as glimepiride was orally administered, blood was taken at predetermined time intervals and the concentrations of glimepiride in serum were determined using HPLC method with UV detctor. The dissolution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC_(t), C_(max) and untransformed T_(max). The results showed that the differences between two formulations based on the Amaryl were -3.70, -8.28 and 0.61% for AUC_(t), C_(max) and T_(max), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25)(e.g., log(0.84)∼log(1.04) and log(0.82)∼log(1.03) for AUC_(t) and C_(max), respectively). Thus, the criteria of the KFDA guideline for the bioequivalence were satisfied, indicating Glimed tablet and Amaryl tablet were bioequivalent.

농구선수와 일반학생의 성격특성에 관한 연구

조동진,김재현,김승동 조선대학교 스포츠과학연구소 1998 스포츠科學硏究 Vol.9 No.-

The purpose of this study is to clarify the difference of personality between college basketball players and college students, 81 college basketball players and 120 college students answered a questionnaire which is consisted of 7 indices (kindness, stability, domination, mobility, boldness, forgiveness and toughness). 1) A comparison of personality between college basketball players and college students. There is no difference in kindness, mobility and forgiveness between the two. However, in cases of stability, domination, boldness and toughness, basketball players are significantly different from college students. Thus, it can be concluded that college basketball players are more stable, bold and tough than college students. 2) A comparison of personality among positions of basketball players (guard, forward and center forward). There is no difference in mobility and stability among positions of basketball players. Guards get more scores in boldness and dominance, Forwards get more scores in toughness and Center Forwards get more scores in kindness and forgiveness.