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      • KCI등재

        Shelf Life Determination of Precooked Frozen Meat Dumplings

        Lee, Young-Chun,Yang, Hyung-Sub,Kim, Dong-Ho 한국산업식품공학회 2002 산업 식품공학 Vol.6 No.3

        Quality of frozen foods is significantly affected by the storage temperature and tie, and the consumers' demand for safe quality frozen foods is increasing. The objective of this research was to estimate the shelf life of frozen cooked meat dumplings, based on the changes in the selected physico-chemical and sensory quality attributes. Precooked frozen meat dumplings sampled from the same lot produced at a frozen food company in Seoul were stored at -10, -15, and -20℃. The meat dumplings sampled at 3- to 4-week intervals were subjected to the determination of volatile basic nitrogen (VBN), thiobarbituric acid (TBA), peroxide value (POV), surface color and shear value after thawing at 5℃ for 15 h. High quality life (HQL) was determined through the triangle test and practical quality life (PQL) through the scoring test. VBN, TBA and POV increased as the storage period was increased. HQL of the frozen meat dumplings were 189 and 252 days at -10 and -15℃, respectively. The estimated PQL were 349, 475, and 491 days at -10, -15, and -20 ℃, respectively. Statistical analysis indicated that there were significant relationships between sensory scores and VBN and POV of the stored meat dumplings. VBN was selected as the most reliable objective quality index for the shelf life determination (PQL) of the precooked frozen meat dumplings.

      • KCI등재

        림프종 환자에서의 갈륨, TI-201 그리고 Tc-99m MIBI 섭취의 비교

        천경아,조인호,원규장,이경희,이형우,현명수,이재태,이규보 영남대학교 의과대학 2002 Yeungnam University Journal of Medicine Vol.19 No.2

        Purpose; Ga-67 scintigraphy has been used for the evaluation of tumors, especially lymphoma. Recently, Tl-201 and Tc-99m MIBI were also used to tumor imaging. Tl-201 and Tc-99m MIBI had better physiologic characteristics than Ga-67, so we studied 32 biopsy proven lymphoma patients (male 24, female 8, mean age 46 years) with Ga-67, Tl-201 or Tc-99m MIBI and compared the scan findings. Materials and Methods: Twenty-three of 32 patients were injected 74-111 MBq (2-3 mCi) of Tl-201, before chemotherapy and imaged with dual-headed SPECT (Prism 2000, Picker, USA) at 30 minutes after injection. Delayed images were obtained after 3 hr in 8 patients. Twenty seven of 32 patients were injected 740 MBq (20 mCi) of Tc-99m MIBI and imaged at 30 minutes after injection. 111-185 MBq (3-5 mCi) of Ga-67 was injected in 12 patients and imaged at 48 and 72 hours after injection. Twenty eight patients were diagnosed as non-Hodgkin's lymphoma and others were Hodgkin's lymphoma. Results: Twenty patients were positive on Tl-201 scan and 3 patients showed negative findings. One of these 3 patients, Tc-99m MIBI and Ga-67 scan were positive. Twenty two patients were positive on Tc-99m MIBI scan and 5 patients showed negative findings. One of these 5 patients, Tl-201 was positive and 2 were positive on Ga-67 scan. Ten of 12 patients showed positive findings on Ga-67 scan. The sensitivity of these agents were 83.3%, 87.0% and 81.5% for Ga-67, Tl-201 and Tc-99m MIBI, respectively. The sensitivity was highest in Tl-201 scan, but there were no significant differences among three tests. In this study, there was no significant difference of uptake ratios between early and delayed images of Tl-201. Conclusion: Scintigraphy with Tl-201 and Tc-99m MIBI in lymphoma patients have similar sensitivity with Ga-67.

      • KCI등재후보

        가상주행시험을 위한 차량 운전자 모델 개발

        이홍기,전형호,탁태오 江原大學校 産業技術硏究所 2001 産業技術硏究 Vol.21 No.B

        In this study, a driver model based on the lead-lag controller for stable maneuver of a highly nonlinear, multi-dimensional, numerically stiff multibody vehicle model according to the various handling test requirements such as steady-state cornering, double lange change, etc. is presented The lead-lag controller is developed with lead and lag compensation. Which use the transfer function with cross-over frequency by frequency response method. The proposed driver model is applied to a vehicle model in steady-state and slalom maneuver to verify its effectiveness and validity. The results show that the proposed path control strategy is excellent both in pursuing the desired course and stability of the vehicle.

      • 흰쥐 내측 전정신경핵 뉴론의 자발적 활동성의 발생에 관여하는 이온전류에 관한 연구

        이형재,최정희,천상우 원광대학교 치의학연구소 2003 圓光齒醫學 Vol.12 No.2

        Medial vestibular nucleus (MVN) neurons are found to have spontaneous electrical activity in the absence of any detectable synaptic input. To investigate the contributions of intrinsic mechanisms to the spontaneous activity of MVN neurons, we examined the effects of various channel blockers on spontaneous firing by means of patch clamp recordings. Coronal slice (400 ㎛) of the vestibular nucleus region was sequentially treated with pronase 0.2 ㎎/㎖ and thermolysin 0.2 ㎎/㎖, then single neurons were mechanically dissociated. Almost all the MVN neurons recorded in neonatal rat were shown to have spontaneous resting activity. In 300 nM TTX, spontaneous firing was blocked in all cells tested. In 8 of 11 cells, underlying fluctuation or oscillations in membrane potential was not remained, and hyperpolarization did not produce rebound low-threshold calcium spikes. Although MVN neurons possessed hyperpolarization activated cation current (Ih), cesium had no effect on firing rates. The spike afterhyperpolarization (AHP) is calcium dependent. When Ca^2+ influx was blocked in external Ca^2+ free solution, repetitive firing was abolished and the cell rested at depolarized membrane potentials. Application of apamin (300 nM) caused a profound reduction in the amplitude of the AHP and produced rhythmic burst firing. These findings suggest that the spontaneous activities of MVN neurons is regulated by interactions between the membrane depolarization mainly due to a persistent sodium conductances and hyperpolarization due to the calcium-activated potassium conductances.

      • 양식 넙치(Paralichthys olivaceus)에서 발생한 랩도바이러스성 질병의 병리조직학적 특징

        이남실,강형길,최희정,전세규,박남규,허민도 한국어병학회 2002 한국어병학회지 Vol.15 No.1

        2000년 4월경부터 (수온7-13℃) 우리나라 동해안과 남해안 육상 수조에서 사육되던 넙치에서 체색흑화, 복수저류, 비장종대의 육안적 소견을 보이는 질병이 발생하여 대량폐사를 불러왔다. 병리조직학적 소견으로, 비장과 신장의 조혈조직에서 괴사병변이 주로 나타났다. 비장과 신장의 간질조직에서 괴사소가 관찰되었으며, 임파구, 괴사세포의 침윤이 나타났다. 비장 조직의 전자현미경적 관찰에서 변성혈구 내 세포질에서 탄환형의 바이러스 입자가 관찰되었는데 직경과 길이가 각각 약 50nm, 170nm였다. 이상의 결과로 본 질병은 rhabdovirus에 의한 질병으로 판단되었다. On April of 2000 and February of 2001, a disease characterized by darkening, ascites and enlargement of the spleen occurred in flounder, Paralichthys olivaceus, farmed near northern and eastern coasts of Korea. Various degree of necrosis including liquefactive-type was observed mainly in hemopoietic tissue of spleen and kindney. Certain tissue such as branchial soft tissue including epithelium showed a similar necrotic findings. But some tissues such as intentine had several necrotic clusters of wandering cells, being possibly leukocytes. Necrotic evidences of blood cells were evident in various tissues including hemopoietic tissues. Necrobiotic bodies were frequently encountered in blood smear preparations. Bullet type-virious were detected in the spleenic cells. Each virion was about 500 nm in diameter and 170nm in length. From these results, this disease was thought to be a rhabdoviral disease.

      • Glutamate 억제제가 Pilocarpine에 의한 경련 및 기억장애에 미치는 영향

        천임순,한형수,박정숙,정헌주,이만기,김중영 慶北大學校 醫科大學 1996 慶北醫大誌 Vol.37 No.3

        목적 : Pilocarpine에 의한 경련 및 기억력 저하에 glutamate 수용체가 관련이 있는지 검토하였다. 대상 및 방법 : 생쥐에 pilocarpine을 투여하여 야기되는 경련 및 기억력저하가 glutamate 수용체 길항 약물인 MK-801 및 NBQX를 전처치하였을 때의 반응을 Morris Water Maze의 방법으로 관찰하였다. 결과 : MK-801과 NBQX를 전처치하고 pilocarpine을 투여하였는 바 pilocarpine에 의한 경련유발은 억제되지 않았으나, pilocarpine에 의한 reference memory와 working memory의 저하는 MK-801이나 NBQX를 처치로서 억제되었다. 결론 : Pilocarpine에 의한 경련작용에 비하여 기억력저허가 glutamte 수용체와 관련이 있는 것으로 보인다. The role of glutamate receptors in the genesis of pilocarpine-induced seizure and seizure-related memory deficit was studied using MK-801 and NBQX. After pretreatment with MK-801 or NBQX, pilocarpine was administered intraperitoneally. Both drugs had no effect on the behavioral seizure activity and onset of seizure activity. Memory was tested with reference and working memory version of Morris water maze at 20th day after pilocarpine treatment. Reference and working memory deficit was produced by pilocarpine. These deficit were prevented by MK-801 or NBQX, which were given in once a day for 4 day at 7th to 10th days after pilocarpine treatment. These results show that although MK-801 and NBQX do not have anticonvulsant property they can prevent pilocarpine-induced memory deficit.

      • 가시층 분석 기법을 이용한 경관고도규제계획에 관한 연구 : 진주시 역사경관 보존을 중심으로

        이춘석,강호철,류남형 진주산업대학교 1999 산업과학기술연구소보 Vol.- No.6

        Chinju is famous for an old castle located in downtown. To conserve its historic landscape, some districts on the north of the castle have been under the height regulation. The historic landscape, however, is being seriously disturbed by the huge buildings newly constructed at the south of the castle. So, and alternative height regulation is required to make up its deficiency. This study examined the ‘View Floor Analysis(VFA)’as a height regulation planning tool, and suggested an alternative ‘Building Height Regulation Plan’with its results. The VFA is a new method to find out the maximum building height permissible from the differences between the existing topography and an imaginary floor which repersents building height theresholds, The process of the VFA used in this study was ① digitizing contours, ② converting digital contours to DEM, ③ manipulating control lines(super-imposing & text editing), ④ making visual floor(TIN) and converting it to raster data, and ⑤ map calculating(map algebra). The results were as follows: 1.At most, three stories(9m) buildings were permissilbe in the districts by the rear-gate of the castle, 2.But, very tall buildings over even twenty stories were allowable at Deulmal, Okbong, and the districts near the station. 3.The closer to the castle, the shorter building permissible. And, the closer to the mountains around the city, the taller building allowable.

      • 자궁경부암의 수술 및 방사선치료 후 국소재발 판정에 대한 MR 및 CT 평가

        전하정,이명자,김형석 한양대학교 의과대학 1997 한양의대 학술지 Vol.17 No.2

        The objectives of our study were to analyze the CT and MR findings of local tumor recurrence at vaginal stump in patients of cervical carcinoma treated with hysterectomy and radiotherapy, and to assess the diagnostic value of the MR study. We retrospectively analyzed the CT(n=17) and MR (n=10) findings in 19 patients, who had uterine cervical carcinoma after hysterectomy with radiation therapy (extended-field irradiation and/or brachytherapy). The CT findings of local tumor recurrence were localized mass like lesion(n=5), slightly enhanced infiltrating lesion (n=4) and enhancing mass with central necrosis (n=1). The MR findings wer local iso-signal intensity mass on T1-weighted image and irregular high-signal intensity mass on T2-weighted image. The false positive results were three (two on CT and one on MR), due to inflammation and local fibrosis. On the basis of our study, the CT was the proper screening method for follow up in patients with cervical carcinoma after treatment. But, if any suspicion of tumor recurrence, MR was the useful tool to exclude the local fibrosis and inflammation, and to decide the next studies such as biopsy or observation with MR follow up.

      • 알콕사이드로부터 Sialon-SiC계 미분말의 합성과 분말특성

        이홍림,전명철,이형복 연세대학교 산업기술연구소 1988 논문집 Vol.20 No.2

        Fine Si-Al-OH coprecipitate powder was prepared from Si- and Al-alkoxides by a hydrolysis method. Sialon-SiC composite powder was then fabricated from the Si-Al-OH coprecipitates by carbothermal reduction, nitridation and carbiding reaction method in nitrogen-hydrogen atmospheres. The average size of alpha silicon nitride was about 1㎛ and that of beta sialon was about 0.2-0.3㎛. However, the average size of Sialon-SiC composite powder was about 0.13㎛. Sialon/SiC(45/55) composite powder was hot-pressed at 1750℃ for 60 min in a nitrogen atmosphere. Bending strength, fracture toughness and microhardness were 494.6 MPa, 3.8 MN/m?? and 13.9 GPa. respectively.

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