원광대학교 치과병원 교정과에 내원한 환자의 분포 및 변동 추이에 관한 연구

김준관,김상철 원광대학교 치의학연구소 1990 圓光齒醫學 Vol.1 No.1

1065 patients (male ; 379, female : 686)who visited at depatment of orthodontics in Wonkwang University Dental Hospital form 1983-09-05 to 1990-10-05, were surveyed and analyzed to study the distribution and the trend of malocclusion patterns. 1. The number of visiting, patients has increased, year by year. And female patients has visited more than males. 2. The percentage of the age group form 8 to 15 was 63.8 : above 20, 14.1% : under 7, 10.1%. 3. The patients lived in Iri, Kun San, lk San, Ok Gu, Kim Je, in that order of frequency. The percentage of patients in above addresses was 92.3. 4. Anterior cross bite showed the highest percentage in chief complaints. 5. Hellman dental age Ⅲ b showed the highest percentage in male : Ⅳ a, in female : Ⅳa, in total. 6. The percentage of skeletodental dysplasia was 64.9: dental dysplasia, 24.9%skeletal dysplasis, 10.1%. 7. The percentage of Class Ⅰ malocclusion was 362% : Class Ⅱ division 1, 25.0% : Class Ⅱ division 2, 2.7% class Ⅲ, 36.1%. 8. The percentage of patients, treated with preventive orthodontics, were 38.0: with comprehensive orthodontics, 62.0%, 43.5% of comprehensive orthodontics cases were extraction cases and 56.5%, non-extraction cases. And 4 first bicuspids have been extracted in the highest percentage.

하악과두골절의 외과적 처치 : Dr. 남씨 방법 Dr. Nams Method

민승기,이동근 원광대학교 치의학연구소 1996 圓光齒醫學 Vol.6 No.1

1993년 1월부터 1995년 12월 까지 원광대학교 치과대학 구강악안면외과에 하악과두 골절을 주소로 내원한 환자 25명에 대하여 Dr. 남씨 방법에 의한 관혈적 정복술을 시행하였다. 술후 악간 고정은 2주정도 하였으며 수동적 개구운동 및 능동적 개구 운동을 2에서 4주, 4주이상에서 시행하였다. 술후 약 3개월에서 1년반동안의 검사에서 개구량은 평균 45㎜ 이상 큰 불만없이 벌어졌으며 하악운동량도 비이환측에서 더 많은 하악운동을 보였으나 모두 정상범주를 나타내고있었다. 하악운동을 하고 있는 동안에 관절내 환자 스스로 호소할만할 동통 및 관절잡음이 발견되지 않았으나 가끔씩 이환측 및 비이환측 관절 잡음은 감지되었다. 두 증례에 있어서는 과두의 과도한 흡수를 보였다.

한국인의 미맹출 견치 및 소구치의 근원심 폭경 추정에 관한 연구

윤정현,김상철,조원탁,이소영 원광대학교 치의학연구소 1993 圓光齒醫學 Vol.3 No.2

In order to confirm the method for the prediction of the size of the unerupted canines and premolars in Korean, the mesiodistal widths of the teeth of 156 Korean adults with normal occlusion were measured. The sums of the mesiodistal widths of mandibular incisors, of the maxillary canines and premolars, and mandibular canines and premolars were calculated. And the correlationship of those sums were analyzed. The results were as follows. 1. The correlation coefficient of the sum of the mesiodistal widths of the maxillary canines and premolars to the sum of the mesiodistal widths of mandibular incisors was 0.503 and that of the sum of the mandibular canines and premolars was 0.559. 2. The regression equations between the sum of the mesiodistal width of the mandibular incisors(X) and the sums of the mesiodistal widths of maxillary or mandibular canines and premolars(Y) were as follow. In maxilla, Y = 12.524 + 0.418X In mandible, Y = 10.461 + 0.477X

탈회된 인체 이종골 매식체의 조직반응에 대한 실험적 연구

진국범,김수남,엄인웅,김귀희 원광대학교 치의학연구소 1992 圓光齒醫學 Vol.2 No.2

To evaluate the tissue response of demineralized and undimineralized xenogeneic bone martrix graft in extraskeletal site, we prepared human bone as a implant matrix, and outbred mouse as a recipient. Before clinical application of bank bone of human in Wonkwang university, we should confirm the allogeneic bone grafts as a biologically useful bone graft substitutes, obtained from the patients receiving oral and maxillofacial surgery. The clinical evaluation and histologic studies showed that both (demineralized and undemineralized) xenogeneic bone matrix grafts were not rejected and that they seemed to stimulate new bone formation at the transplantation site. Undemineralized xenogeneic bone martrix grafts showed minimal bone induction and gradual demineralization with slow resorption and showed that the differentiation of cells showing fibroblastic activity adjacent to the soft tissue were slowly and less frequently than demineralized bone. Characteristical differences between the demineralized and undemineralized matrix were the appearance of foreign body giant cells (multinucleated giant cells) and the evidence of slow resorption in undemineralized bone matrix.

치조골수 유래 성체줄기세포의 신경세포분화능에 관한 연구

송제봉 ( Je Bong Song ),유형근 ( Hyung Keun You ) 원광대학교 치의학연구소 2005 圓光齒醫學 Vol.14 No.1

상악제1소구치의 법랑질 두께에 관한 연구

이진한,기태석,오상천,동진근 원광대학교 치의학연구소 2002 圓光齒醫學 Vol.11 No.2

Enamel is the hardest tissue in the body. This property enables enamel to withstand the heavy loads of mastication and resist wear during the mastication. Tooth structures (enamel thickness, size of pulp chamber, etc) are influence to strength of restoration, esthetics, marginal adaptation. This study on the enamel thickness of maxillary first premolar may offer guidance about tooth reduction depth and decision of margin type in tooth preparation. The total sample consisted of 36 permanent maxillary premolars, all of which were from different individuals (16-18 years male and female), extracted for orthodontic treatment. The teeth were fixed in 5% formalin and stored in normal saline. Extracted teeth were embedded in methyl methacrylate block. Only one section was taken from each tooth through buccal and lingual cusp tips in a plane perpendicular to the cervical margin of the crown, and then sectioned through mesiodistal plane, included central groove. Thereafter the cut faces were polished with 800, 1200, 2000 grit SiC paper. Each tooth was photographed at a magnification(×7). Linear measures of enamel thickness were recoded for each sample. The data were analyzed by SPSS (One-Way ANOVA, Scheffe's test). Result obtained were as follows, 1. The thickness of the enamel at the lingual cusp tip was 1.92㎜, buccal cusp tip was 1.42㎜. 2. The thickness of the enamel at the occlusal surface was 1.21㎜ in buccal cusp, 1.23㎜ in lingual cusp, 0.94㎜ in mesial marginal ridge slope and 0.93㎜ in distal marginal ridge slope. 3. The thickness of the enamel at the 1㎜ above cementoenamel junction was 0.40㎜ in buccal side, 0.51㎜ in lingual side, 0.46㎜ in mesial side and 0.47㎜ in distal side. 4. The thickness of the enamel at the 2㎜ above cementoenamel junction was 0.67㎜ in buccal side, 0.82㎜ in lingual side, 0.82㎜ in mesial side and 0.93㎜ in distal side.

연쇄 구균의 세포벽 단백질 추출물이 림프구 활성의 억제에 미치는 영향

상현숙,임미경 원광대학교 치의학연구소 1995 圓光齒醫學 Vol.5 No.1

The inhibitory effect of cell wall extracts of streptococci, have been investigated to know hostparasite relationship or pathogenesis of abscess formation. Streptococci isolated from the infected root canals were sonicated to get cell wall extracts which have been known as one of the major factors of pyogenesis. Lymphocytes separated by density gradient were stimulated with phytohemagglutinin and exposed to cell wall extracts of Streptococcus sanguis, S. mitis, S. uberis, S. mutans(ATCC 10449), and S. jieealis(ATCC 19433). [^3H]-thymidine uptake of lymphocytes was analyzed with scintillation counter and lactate dehydrogenase (LDH) activity was measured with autochemistry analyzer. S. fieealis had the strongest inhibitory effect, beginning at 100㎍/㎖ concentration of sonic extracts. S. sanguis and S. mitis had inhibitory effect at 300㎍/㎖, while S. uberis and S. mutans showed no inhibitory effect on DNA synthesis even at 300㎍/㎖. Each streptococci showed different inhibitory effect on the DNA synthesis of lymphocytes, of which finding indicated wide spectrum of susceptibility of lymphocytes according to streptococcus spp. There were no significant difference of LD activities between control and each streptococcal extracts. Streptococcal sonic extracts did not affect the morphological findings or number of colonies of activated lymphocytes. These finding suggested the inhibitory effect of sonic extract of streptococci to lymphocytes could be detected by DNA synthesis inhibition, not by cellular membrane damage.

히알루로란이 동종골 이식술시 골 형성 과정에 미치는 영향에 관한 연구

김종구,민승기 원광대학교 치의학연구소 2002 圓光齒醫學 Vol.11 No.3

Hyaluronan is an essential component of extracellular matrices. Early in embryogenesis mesenchymal cells migrate, proliferate and differentiate, in part, because of the influence of hyaluronan. Since the features of embryogenesis are revisited during wound healing, including bone fracture repair, this study was initiated to evaluate whether hyaluronan has an effect on osteogenesis in early stage of wound healing. Grafting bone chip was applied on the two squared shaped bone defects on the total 60 rat calvarium about 7×7 mm size which were made with electric drill intentionally, the right side was grafted with allogeneic bone and the left side was autogenous bone grafting. In experimental groups, grafting materials were hydrated with 1.0 mg/ml concentration of hyaluronan solution before surgery for 30 minutes. The calvarial bone defects were covered with layer suture. In postoperative 1, 2, 4, 6 and 8 weeks, total experimental rats were sacrificed and evaluated under light microscope with routine H&E, Masson Trichrome and toluidine blue stain and found initial osteogenesis at postoperative 1 and 2 weeks under electric microscope. In postoperative 1 and 2 weeks, inflammatory changes in the wound sites were more prominent in bones to which hyaluronan had been applied. But, new bone formation had been induced by day 7 on both peri- and endosteal surfaces of the grafted areas. Newly formed trabecular bones were filled in grafted wound and the active bone remodeling by osteoblast and osteoclast had occurred till postoperative 4 weeks. The mature bone formation on both calvarial bone defects after 4 weeks without distinctive difference between control and hyaluronan groups. These results suggest that high-molecular hyaluronan is capable of accelerating new bone formation through mesenchymal cell differentiation in bone grafting.

자일리톨 함유 식품이 합성 수산화인회석에 대한 Streptococcus mutans의 부착에 미치는 영향에 관한 실험적 연구 : An in vitro study

이재춘,김대업 원광대학교 치의학연구소 2002 圓光齒醫學 Vol.11 No.2

There have been efforts that inhibit development of dental caries by sugar substitution. But, it is controversial if xylitol has anticariogenic effect in the presence of sucrose. And there are few papers dealing with the combined action of xylitol and sucrose. For the purpose of resolving this controversy, the author investigated the effect of xylitol on enamel demineralization and on adhesiveness of S. mutans to hydroxyapatite in the presence of sucrose. Five experimental solutions were prepared as follows: (S: sucrose, X: xylitol) Group 1: BHI broth Group 2: BHI + 1 % S Group 3: BHI + 0.75% S+0.25% X Group 4: BHI + 0.5% S + 0.5% X Group 5: BHI + 0.25% S + 0.75% X Group 6: BHI + 1 % X Each solution was inoculated with 100㎕ of S. mutans JC-2. And saliva coated hydroxyapatite beads were put into each experimental solution. And then each solution was incubated at 37℃ under anaerobic condition. After incubation, the adhesiveness of S. mutans on hydroxyapatite was evaluated. The Vickers hardness numbers were measured on extracted human primary teeth, and these teeth were dipped into the same experimental solution and incubated at 37℃ under anaerobic condition for 48hours. Surface microhardness were measured again after incubation. The obtained results were as follows; 1. In the presence of sucrose, xylitol can reduce the adhesiveness of S. mutans on hydroxyapatite surface from the ratio of 25% sucrose to 75% xylitol(P<0.05). 2. In the presence of sucrose, xylitol can reduced demineralization of primary teeth enamel surface from the ratio of 50% sucrose to 50% xylitol(P<0.01).

처리방법에 따른 혈소판 함유 혈장의 농축도에 관한 연구

김형주 ( Hyung Ju Kim ),민승기 ( Seung Ki Min ) 원광대학교 치의학연구소 2005 圓光齒醫學 Vol.14 No.2