전기점화기관의 분사방식에서 메탄올의 첨가가 기관성능에 미치는 영향에 관한 연구

김치원,한병호,우학남 慶南大學校 附設 工業技術硏究所 1994 硏究論文集 Vol.12 No.-

석유 자원의 유한성으로 인한 탈석유화를 위한 방법으로 대체연료로서 각광을 받고 있는 메탄올을 시험연료로 사용 하였다. 메탄올 연료는 쳔연가스, 석탄 혹은 석유계 연료인 LPG, 나프타 등으로 부터 합성할수 있으므로 가격 및 수급면에서 석유를 대신할 수 있는 연료로 평가된다. 메탄올은 가솔린에 비해 고옥탄가 연료로 고압축비화가 가능하여 출력 및 열효율의 향상을 기할수 있고 기화잠열이 커서 흡입계에 냉각효과를 크게 하여 체적효율을 증가시키므로 같은 당량비에서 출력을 향상시킬 수 있다. 본 연구에서는 메탄올-가솔린 혼합연료를 흡기관내에 분사하기 위해 전자제어식 연료분사장치를 설계 제작하였다. 전자제어식 연료분사장치는 연료의 분사시기를 검출하는 검출부와 분사량을 조절하는 타이머회로 및 인젝터로 구성하였다. Lately, Methyl alcohol to be concerned has greatly stimulated as the alternative fuel for the gasoline enigine due to the shortage of energy source of petroleum. With the comparision of gasoline and methanol, the merits of properties of methanol fuel are the effect of decreasing the mixture temperature and increasing the volumetric efficiency of the mixture induced with the high latent heat of vaporization, the results of permitting the high compression ratio in engine are increased the energy efficiency, and brake horse power because of a high research octane rating compared to gasoline. The objective of this work is to design and to investigate the effect of using fuel injection system with electronic control circuit at fuel supply system. Therefore, the electronic controlled fuel injected system has consisted a circuit to detect injection timing and control injection quantity.

솔레노이드 밸브를 이용한 고압가스의 유량제어

심한섭,이치우,김남경,안국찬,남궁재관 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

Dynamic flow characteristics of a solenoid valve are affected by pressure difference in inlet and outlet of orifice, gas temperature, and supply voltage of a coil. In this paper, the dynamic flow characteristics for deviations of various conditions are studied Static and dynamic flow for variation on-time of a solenoid valve open signal are measured in basic bench test. The solenoid valve is applied to a compressed natural gas(CNG) engine test for validation of flow control performance. The experimental results show that flow of high pressure gas can controlled precisely by using a solenoid valve.

신라대학교 주변 백양산의 동물상

노치권(외 6명) 신라대학교 자연과학연구소 2012 自然科學論文集 Vol.22 No.-

To study fauna of Silla University located in Mt. Baek-yang, we conducted six surveys from 29 May 2011 to 28 April 2012. We found five phyla 41 orders 197 species of animals inhabiting in this area: four phyla 27 orders 163 species of invertebrates and in vertebrates one order six species of fishes, three orders nine species of amphibians and reptiles, six orders 14 species of aves, and four orders five species of mammals. Of these species, some Korean endemic species were included: a fish of Rhodeus uyekii in a pond near main gate of this university, a frog of Rana coreana in a creek near a dormitory, and a rabbit of Lepus coreanus and a water deer of Hydropotes inermis in a grass region near a main stadium. A kind of hawk, Falco tinnunculus as a natural monument (animal) of no. 323-8, was observed on a building of medical and life science. A blue frog of Hyla japonica as a variation was found near a spring resort. Therefore, this area is considered an ecologically important area having a high animal diversity.

멜라닌뇨증을 동반한 전신 전이성 악성 흑색종 1예

박준수,이성우,김상원,한치동 대한피부과학회 2004 大韓皮膚科學會誌 Vol.42 No.2

A 31-yeat old woman had been diagnosed as a metastatic melanoma of unknown origin 7 month before. Multiple cutaneous nodules had developed about 2 months before. When she visited our dermatologic clinic, the number of cutaneous nodules was increased and her urine was dark-brown colored. Histopathologically, the cutaneous nodule had typical for metastatic melanoma. After cytospin of her urine, we observed melanin dusts within macrophage on Fontana-Masson stain. This is a rare case showin-g melanuria. (Korean J Dermatol 2004;42(2):211~213)

사마귀류 추출물의 생물학적 활성 비교

허진철,황재삼,강석우,윤치영,이상한 慶北大學校農業科學技術硏究所 2007 慶北大農學誌 Vol.25 No.-

In order to investigate the availability of insect resources for agrobiotechnological or medical purposes, we examined antioxidant (DPPH and FRAP assay) and cell viability by oxidant stress and NO inhibition assay by treatment of the extracts of Statilia maculata Thunberg, Tenodera angustipennis Saussure and Tenodera aridifolia Stoll. We found that Tenodera angustipennis Saussure and Tenodera aridifolia Stoll extract (DW, etanol, methanol) had high levels of anti-oxidant activity, whereas Tenodera aridifolia Stoll extract showed increased cell viability by hydrogen peroxide and inhibition of NO production. These findings suggest that Statilia maculata Thunberg, Tenodera angustipennis Saussure and Tenodera aridifolia Stoll, extract have potentials to be developed for agrobiotechnology or medicinal use, indicating that mechanistic study including inhibition against molecular inflammation will show a possibility for the development of useful insect resources.

한국인 정신분열병 환자의 지연성 운동장애와 $CYP2D6^*4$ 및 $CYP2D6^*10$ 다형성들의 연합에 대한 고찰

우성일,강동우,서한길,김봉조,이인상,정근화,박소영,정치영,이환철,정경천,손진욱,Woo, Sung-Il,Kang, Dong-Woo,Seo, Han-Gil,Kim, Bong-Jo,Lee, In-Sang,Jeong, Geun-Hoa,Park, So-Young,Jung, Chi-Yeong,Lee, Hwan-Cheol,Jeong, Kyeong-Cheon,Sohn, 대한생물정신의학회 2000 생물정신의학 Vol.7 No.2

P450 CYP2D6 enzyme(=debrisoquine hydroxylase) is known to metabolize many neuroleptics and some genetic polymorphisms in the CYP2D6 gene were reported to be associated with tardive dyskinesia(TD). We investigeted the association of two genetic polymorphisms in the CYP2D6 gene, $CYP2D6^*4$ and $CYP2D6^*10$, with TD in Korean schizophrenic subjects. Subjects consisted of 71 Korean schizophrenics and TD was evaluated using the Abnormal Involuntary Movement Scale (AIMS). There were no statistically significant differences in the demographic variables of age, male to female percentage and the current antipsychotic(CPZ equivalent) dose between the group with TD and the group without TD. But the duration of antipsychotic drug exposure was significantly higher in the group without TD(p=0.000, by independent t-test). The mean AIMS score in the group with TD was $11.2{\pm}6.6$(S.D.). Genotypings for the presence of $CYP2D6^*4$ and $CYP2D6^*10$ were done using PCR amplifications and endonuclease digestions. There were no statistically significant genotypic and alleleic associations between TD and $CYP2D6^*4$(by chisquare tests), and between TD and $CYP2D6^*10$(by chi-square tests). These results indicate that the $CYP2D6^*4$ and $CYP2D6^*10$ polymorphisms have no significant roles in the causation of TD.

혼합형 자가면역성용혈성빈혈과 동반된 Evans 증후군 1례

선길홍,윤찬영,박상곤,박경희,우정주,한경택,김진화,김영훈,정춘해,박치영 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

Evans syndrome is defined as a simultaneous or sequential occurrence of autoimmune hemolytic anemia and autoimmune thrombocytopenia. Autoimmune hemolytic anemia (AIHA) is usually induced by IgG warm autoantibody or cold-active IgM antibodies reacting specifically with antigens associated with a patient's RBC. AIHA is a fairly uncommon disorder, with estimates of the incidence at 1 to 3 cases per 100,000 per year. Mixed-type AIHA is a relatively uncommon form of AIHA, with studies noting the incidence of 7-8% among cases of AIHA. We experienced a patient, 46-year-old woman who was diagnosed having a very rare clinical presentation of mixed warm and cold antibody mediated Evans syndrome. She was treated with corticosteroid therapy only and has been maintaining a complete response for 15 weeks. 저자들은 혼합형의 자가면역성 용혈성 빈혈과 자가면역성 혈소판 감소증이 동시에 발생한 혼합형 Evans 증후군으로 진단하고 스테로이드 요법 후 혈액학적으로 회복된 상태로 15주가 지난 현재 steroid 5 mg/일 까지 감량한 상태에서 추적 관찰 치료중인 46세 여자 환자를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

신규 세파로스로린 항생제 DWC-751 합성과 물성연구

이재호,정종근,김명구,안상근,최영기,문치장,오세한,성무제,윤길중,신종만,김학형,김영도,박준우 한국응용약물학회 1993 Biomolecules & Therapeutics(구 응용약물학회지) Vol.1 No.1

The synthesis and physicochemical properties of a novel cephalosporin, DWC-751 are described. DWC-751, (6R, 7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-3-[(1-methylbenzotriazol-3-ium)methyl]-ceph-3-em-4-carboxylate monosulfate(IV_a) was conveniently obtained by the conversion of compound(IV) into the crystalline monosulfate. Adjusting pH 4.8-5.2 in aqeous solution of the crude crystalline, compound(IV) in the form of a crystalline pentahydrate was prepared with a high degree of purity. The influence of the various organic and inorganic acids on the solubility of compoud(IV) and its salts, was examined. Particularly, the solubility of DWC-751 was 92 ㎎/㎖ at pH 1.7 and 233 ㎎/㎖ at pH 3.0. DWC-751 showed a broad antimicrobial spectrum against gram-positive and negative bacteria.

CD34+ 조혈 모세포 이식 2례

김정아,정현식,김원석,윤성수,이홍기,박찬형,박성규,김동욱,이종욱,한치화,민우성,김춘추,김동집 대한조혈모세포이식학회 1996 대한조혈모세포이식학회지 Vol.1 No.1

Background: In most solid tumors, the CD34 antigen has not been detected, so positive selection of CD34+ cells may reduce tumor cell contamination and the CD34+ cells are capable of reconstituting hematopoiesis. We tried CD34+ cell transplantation in two patients. Method: CD34+ cells from chemotherapy + G-CSF mobilized PBPCs or bone marrow were positively selected with an avidin-biotin immunoadsorption column (CEPRATE SC system). Case 1. One course of chemotherapy using cyclophosphamide(200㎎/㎡) and etoposide (4.2g/㎡), combined with G-CSF(5㎍/㎏) S.C. was used in a relapsed lymphoma patient. This patient responded to the induction chemotherapy. CD34+ cells from harvested bone marrow were selected by the CellPro immunoadsorption column. The total number of mononuclear cells loaded onto the CellPro was 2.4×10^(8)/㎏, with 1.1% CD34+ cells. After column separation, the total number of positively selected cells was 5.16×10^(6)/㎏. The number of CFU-GM was 76.8×10⁴/㎏. This patient was treated with melphalan (140㎎/㎡) and TBI (1200cGy) and the positively selected CD34+ cells were infused. The time to neutrophil recovery greater than 0.5×10^(9)/L was 19 days and the time to platelet recovery greater than 50×10^(9)/L was 21 days. Case 2. Two courses of mobilizing chemotherapy were given 4 weeks apart using taxol(210㎎/m2) and adriamycin(60㎎/m2), combined with G-CSF(5㎍/㎏) S.C. in a breast cancer patients with 7 axillary node metastasis. CD34+ cells from each single leukapheresis product were selected by the CellPro immunoadsorption column. In the first collection, the total number of nucleated cells was 4.4×10^(8)/kg, with 0.42% CD34+ cells. In the second collection, the total number of nucleated cell was 2.8× 10^(8)/㎏ with 0.43% CD34+ cells. After colum separation, the total numbers of collected cells were 4.0×106/kg and 4.8×10^(6)/kg, the total number of CD34+ cells were 1.2×10^(6)/㎏ and 0.82×10^(6)/㎏. Colonogenic assays of positively selected CD34+ cells gave rise to myeloid erythroid, and multilineage colonies, with a median of 190 CFU-GM, 190 BFU-E, and 164 CFU-GEMM per 1×10³ adsorbed cells, respectively. High-dose chemotherapy with cumulative doses of 40mg/㎡ mitoxantrone, 750mg/㎡ thioptepa, and 1000mg/㎡ carboplatin was administered. Positively selected CD34+ cells were rapidly infused 24 hours after the end of high-dose chemotherapy. The time to neutrophil recovery greater than 0.5×10^(9)/L was 16 days and the time to platelet recovery greater than 50×10^(9)/L was 20 days.

Public Behavior in Korea and China in Acquiring Particulate Matter Information

Chi Woo Han,Ga Won Byeon,Lin Wang,Haiying Wang 대한인간공학회 2022 대한인간공학회 학술대회논문집 Vol.2022 No.10