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유전성 구상적혈구증환자에서 Parvovirus B19 감염에 의한 일과성 골수무형성증 1예
박상곤,윤찬영,박치영,정춘해 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.3
Hereditary spherocytosis is a kind of hemolytic anemia caused by defect of RBC membrane and show symptoms such as anemia, jaundice and splenomegaly. The disease become serious problem when the symptom of it become severe after infection and parvovirus B 19 are known to cause transient aplastic crisis in this disease. Human parvovirus B19 is a small, non-enveloped, single-stranded DNA virus. The virus is spread by respiratory droplets, and infects within erythroid progenitor cells, which results in the arrest of erythropoiesis. Erythema infectiosum is the primary clinical presentation linked to parvovirus B19 infection in childhood. The clinical features of this infection in healthy individuals are asymptomatic infection, acute arthritis and transient anemia. But, individuals with a history of hematologic abnormalities, including increased RBC destruction (eg, sickle cell disease, hereditary spherocytosis) or decreased RBC production (eg, iron deficiency anemia), can present with transient aplastic crisis. Patients with congenital or acquired immune deficiencies are at risk of developing chronic infection and lead to pure red cell aplasia. We report the case of transient aplastic crisis due to parvovirus BI9 infection in hereditary spherocytosis.
박상곤,김영대,강지은,신정현,신병철,박차영,정춘해 朝鮮大學校 附設 醫學硏究所 2003 The Medical Journal of Chosun University Vol.28 No.2
Rhabdomyolysis is a syndrome characterized by muscle necrosis and release of intracellular muscle constituents into the circulation. The spectrum of causes is quite broad and included disorders of traumatic, metabolic, infectious and toxic origin. However, rhabdomvolvsis and acute renal failure following bee sting is rare and its pathogenesis is not well known. We experienced a case of 63-year-old man with acute renal failure and rhabdomyolysis caused by bee sting. He was stung by bee on scalp and neck. Oliguria was developed within several hours. He has fully recovered after general supportive care including fluid therapy and diuretics. This case demonstrates that rhabdomvolysis with consequent acute renal failure are able to developed by bee sting.
박상곤,주성현,박원규,이광희 경상대학교 농업생명과학연구원 2010 농업생명과학연구 Vol.44 No.5
To examine the relationship between climate and tree-ring growth of Pinus densiflora S. et Z. growing in the ridges of the Baekdudaegan, it was analyzed the sample cores of 48 trees were collected from 21 sites. After the pattern of tree rings of all Pinus densiflora were cross-dating each other, it was recognized the growth of Pinus densiflora was affected by climate largely when tree-ring chronologies were standardized to remove the age-related growth. As a cluster analysis was conducted to examine the similarity of chronologies, three clusters were classified, the tree-ring growths of Pinus densiflora was not by regional or elevational gradients but by the growth tree-ring width amplitude as micro-site growth environments. Correlation coefficients between the chronologies of three clusters and monthly climate (temperature and precipitation) factors were obtained. As a result, tree-ring growth of Pinus densiflora was more affected by temperature than precipitation and the trees of high-growth cluster possessed less climatic influences. 백두대간의 마루금일대에 자라는 소나무 연륜생장과 기후와의 관계를 알아보기 위하여 21개 지역에서 48본 시료의 연륜을 분석하였다. 모든 지역의 소나무 연륜패턴이 서로 크로스데이팅 되어 우리나라 소나무의 생장이 기후에 크게 영향을 받는다는 것을 알 수 있었다. 이들 연륜연대기는 3개의 군집으로 구분할 수 있었는데, 지역적으로 그리고 해발 고도에 따라 분류되지 않아 백두대간에 분포하는 소나무의 연륜생장은 지역이나 고도보다는 미소 (microsite) 생육환경에 따른 생장량의 대소에 따라 분류되는 것을 알 수 있었다. 백두대간 소나무의 연륜생장과 기후(월 강수량과 월 평균기온)와의 관계를 상관계수로 분석한 결과, 백두대간 소나무의 연륜생장은 강수보다는 기온에 영향을 많이 받으며, 생장이 양호한 군집이 기후의 영향을 덜 받는 것으로 나타났다.