플라즈마 이온주입기에서의 시변환 쉬스 연구

김곤호,김건우,김영우,최영도,김종식,김상진,한승희,홍문표 漢陽大學校 工學技術硏究所 1998 工學技術論文集 Vol.7 No.1

Abstract- In a plasma source ion implantation, the target is successively biased by negative voltage pulses with an intrinsic finite rise time, resulting in the time-dependent sheath formation around the target. Measurement of time-dependent sheath during the pulse rise show the ion matrix sheath development which is in proportion to square root of time and pulse rise rate over plasma density but independent of the ion mass.

Class Disparity and Prosperity Gospel in Korea after the IMF Crisis

Sung-Gun Kim 한국종교사회학회 2016 종교와사회 Vol.4 No.2

The church has always been irresolute concerning the spiritual value of material wealth. Usually taking the moral high ground, the church has been renouncing excessive wealth in favor of a modest and sacrificial lifestyle. Considering the historical shift from aristocracy to meritocracy which endowed money a new moral quality in the West, we can see that South Korea has been going through a similar transformation with 1) the close bond between neo-Pentecostalism and the prosperity gospel and 2) the rise of meritocracy alongside the nation’s ‘compressed’ modernization. This study endeavors to find further evidence of this transformation with reference to Reverend Dong-Ho Kim’s ‘righteous riches.’ Reverend Kim’s conservative view on the poor and the rich is not a new perspective but only a Korean version of American prosperity gospel without a keen consciousness on social justice. The popularity of Reverend Kim’s teachings among the middle class shows that the ‘status quo’ ideology on social inequality is in fact largely derived from Korean Protestantism which has a legacy of American Biblical literalism.

Lidocaine, Thrombin, Epinephrine 의 항균효과

김진우,이동건,전혜선,김승준,김석찬,안중현,김치홍,권순석,김영균,김관형,문화식,신완식,송정섭,박성학 대한감염학회 2005 감염과 화학요법 Vol.37 No.6

목적 : 기관지내시경 검사에서 흔히 사용되는 국소마취제인 lidocaine과 내시경시 지혈목적으로 사용되는 thrombin과 epinephrine이 각종 균주에 미치는 항균효과에 대해 알아보고자 하였다. 재료 및 방법 : 균주는 가톨릭대학교 성모병원에서 2004년 3월부터 2004년 9월까지 임상검체 에서 동정된 S. aureus, S. pneumoniae, K. pneumoniae, P. aeruginosa 각각 42, 42, 42, 43주를 대상으로 하였다. Lidocaine, thrombin, epinephrine 감수성 검사는 National Committee for Clinical Laboratory Standards (NCCLS, 2002)의 기준에 따랐다. 결과 : Lidocaine은 S. aureus, S. pneumoniae, P. aeruginosa에서 MIC_(50), MIC_(90) 모두 20,000 ㎍/mL 이었다. K. pneumoniae는 각각 10,000 ㎍/mL이었다. Thrombin은 S. aureus와 P. aeruginosa에서 MIC50 500 lU/mL 과 MIC_(90) 500 IU/mL 이상이었고, K. pneumoniae에서는 MIC_(50)과 MIC_(90)이 모두 500 lU/mL이상이었으나 S. pneumoniae에서는 MIC_(50)과 MIC_(90)은 125 IU/mL이었다. Epinephrine은 K. pneumoniae, S. pneumoniae에 대한 MIC_(50), MIC_(90)가 모두 >500 ㎍/mL이었고, S. aureus와 P. aeruginosa에 대한 MIC_(50), MIC_(90)가 모두 500 ㎍/mL이었다. 결론 : 기관지 내시경 검사에서 흔히 쓰이는 lidocaine, thrombin, epinephrine 등의 약제들이 호흡기 질환의 흔한 병원균인 S. aureus, S. pneumoniae, K. pneumoniae, P. aeruginosa 균주들에 대해 항균 효과가 있을 수 있어 세균배양검사에 영향을 미칠 수 있겠다. Background : We performed this stody to find out about antimicrobial effect of lidocaine which is commonly used local anesthetic, and thrombin and epinephrine used for hemostasis during bronchoscopic procedures. Materials and Methods : The microorganisms that were cultured from specimens obtained during bronchoscopy were Staphylococcus aureus (n=42), Streptococcus pneumoniae (n=42), Klebsiella pneumoniae (n=42), and Pseudomonas aeruginosa (n=43) collected from St. Mary's Hospital, from March to Sep 2004 were used for susceptibity testing. Susceptibility to lidocaine, thrombin, and epinephrine were tested according to the National Committee for Clinical Laboratory Standards. Result : MIC_(50) and MIC_(90) of lidocaine for S. aureus, S. pneumoniae, P. aeruginosa were all 20,000 ㎍/mL and that for K. pneumoniae were 10,000 ㎍/mL. MIC_(50) and MIC_(90) of thrombin for both S. aureus and P. aeruginosa was 500 IU/mL and above 500 IU/mL, respectively; that for K. pneumoniae were all above 500 IU/mL and for S. pneumoniae they were 125 IU/mL, MIC_(50) and MIC_(90) of epinephrine for K. pneumoniae and S. pneumoniae were above 500 ㎍/mL; that for S. aureus and P. aeruginosa were 500 ㎍/mL. Conclusion : We observed possible antimicrobial effect of lidocaine, thrombin, and epinephrine in vitro against pathogens such as S. aureus, S. pneumoniae, K. pneumoniae, P. aeruginosa, which are common respiratory microorganisms. The use of these agants could affect the result of bacterial culture.

조혈모세포이식 환자에서 침습성 진균 감염에 대한 Micafungin의 예방 효과 및 안전성

김시현,이동건,최수미,권재철,박선희,최정현,유진홍,이성은,조병식,김유진,이석,김희제,민창기,조석구,김동욱,이종욱,민우성,박종원 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

Background: Micafungin, a potent inhibitor of 1,3-β-D-glucan synthase, is a novel antifungal agent of the echinocandin class. In vitro study showed that micafungin was effective against Aspergillus species as well as Candida species, but clinical data on the prophylactic efficacy against invasive fungal infections (IFIs) other than candidiasis are still lacking. Materials and Methods: We identified 60 consecutive adult hematopoietic stem cell transplantation (HSCT) recipients who received at least 3 doses of micafungin during neutropenic period. Micafungin was started as an alternative in patients who were intolerant or had adverse events (AEs) to primary prophylactic antifungal agents. We retrospectively reviewed the medical records and analyzed the efficacy and safety of micafungin for prophylaxis against IFIs. Results: The patients either had autologous (n=9) or allogeneic (n=51: 1 syngeneic, 24 sibling, 26 unrelated donor) HSCT. Itraconazole oral solution (n=58) was the most frequently used first line antifungal agent for prophylaxis and was administered for median 11 days. The most frequent cause of switch to micafungin was vomiting (n=42). The duration of neutropenia and micafungin administration was median 13 and 12 days, respectively. A successful outcome was achieved in 45 (75%) patients. Empirical antifungal therapy was initiated in 13 (22%) patients. There were 2 cases (3.3%) of breakthrough fungal infections which comprised a probable invasive pulmonary aspergillosis and a possible invasive fungal sinusitis. There was no case of invasive candidiasis. A total of 53 (88%) patients experienced at least one AE regardless of causality during micafungin administration. The most frequent AEs were hypokalemia, vomiting, diarrhea, and elevated serum aspartate aminotransferase or alanine aminotransferase. Among the aforementioned AEs, only 1 case of diarrhea could be classified as a probable relation with micafungin when causality was assessed. There was no AEs that caused discontinuation of micafungin. Conclusions: Micafungin seems to be a safe and effective agent for prophylaxis of IFIs including aspergillosis as well as candidiasis in HSCT recipients. However, further large, prospective, and randomized comparative studies are warranted for aspergillosis.

Lactobacillus plantarumCLP-1이 돼지바이러스에 미치는 효과

이건희(Gun-Hee Lee),김영희(Young-Hee Kim),조현아(Hyeon-A Cho),강성기(Sung-Gi Kang),김동건(Dong-Gun Kim) 한국생물공학회 2011 KSBB Journal Vol.26 No.1

To isolate Lactic acid bacteria for animals, we have screened from Kim-chi, swine intestine, swine feces, and dairy products by random selection and anti-viral, antipathogenic bacteria test. Among them, CLP-1 shown that inhibitory effect against rotavirus, porcine epidemic diarrhea (PED) virus, Salmonella sp, and E.coli. By examining biological property, API-ZYM and identified Lactobacillus plantarum by 16S rDNAgene sequence. CLP-1 determined resistance to low pH and bile salt. Futhermore, the cell body of CLP-1 adhered to the intestinal epithelium tissue of swine and Caco-2 cell. CLP-1 was examined on cell immune system modulating activity in vitro. The whole cell and cell culture supernatant was increasing of interferon-β activity. And then, CLP-1 increased prevention effect by Salmonella enteritidis infection in SPF chickens. And we determined similar result in pigs.

분자유전학적방법에 의해 확진된 Leber씨 유전성 시신경병증 2예

김응규,김종환,김상진,예종수,김성은,허경,원인건,황정민 대한신경과학회 1998 대한신경과학회지 Vol.16 No.1

효율적인 군 전직지원체제 정립 방안

정철영,고재관,황원채,윤희철,박가열,김재호,이성식,김동승,표성일,이건남,양안나,최수정,김은석 한국직업능력개발원 2008 직업능력개발연구 Vol.11 No.1

이 연구의 목적은 제대군인에 대한 효율적인 전직지원을 위해서 현행 전직지원 프로세스에 대한 개선 안과 이에 따른 국방부, 국가보훈처 등 제대군인 전직지원관련 기관 간의 역할분담 및 연계방안에 대해서 제안하는 것이다. 연구는 크게 세 가지 과정을 거쳤다. 첫째, 국내 군 전직지원 실태를 분석하여 문제점과 시사점을 도출하였다. 둘째, 이러한 문제점과 시사점, 군 전직지원 선행연구를 종합하여 효율적인 군 전직지원 프로세스 안을 제시하였다. 셋째, 구축한 군 전직지원 프로세스 안에 따라 주요 군 전직지원 관련 기관인 국방부, 국가보훈처의 역할 분담 안을 제안하였다. This study aims to suggest an improvement plan for the support process of effective occupation change for discharged soldiers and then role assignments among related institutions for supporting discharged soldiers such as Ministry of Defense, Ministry of Patriots and Veterans Affairs, Ministry of Labor and the cooperation plan among the institutions. The study was made in three steps. First, after analyzing currents support facts and status for discharged soldiers, it induced its problems and implications. Second, integrating the findings of previous studies related to support plan on occupation changes for the discharged soldiers, Problems and implications mentioned above, it constructed effective occupation change process for discharged soldiers. Then, according to the established process, it suggested role assignments such as Ministry of Defense, Ministry of Patriots and Veterans Affairs, Ministry of Labor.

SNCM강의 피로균열의 발생 및 전파속도에 미치는 질화처리의 영향

김민건,이상호 강원대학교 산업기술연구소 2003 産業技術硏究 Vol.23 No.A

Effect of nitriding on fatigue crack imtiation and growth rate has been studied on SNCM. Specunens were nitnded for 15 hr at 860℃. The fatigue limit of nitrided specunens was superior to that of annealed(860℃. 15 hr) specimens. Based on detailed observations of slip band and micro crack initiation, it is concluded that the excellent fatigue limit of nitrided specunens is attnbuted to improved slip initiation resistance by nitriding The charactenstic of fatigue crack growth rate of nitrided specimens was investigated and compared with those of annealed specunens It was found that by nitriding the crack growth rate was markedly decreased and the threshold stress intensity factor range was improved. It is concluded that the excellent fatigue limit of nitnded specunens is also attributed to unproved fatigue crack growth rate and threshold stress intensity factor range by nitriding

슬라이딩 모드 제어를 이용한 AC서보모터의 원호보간 오차개선에 관한 연구

김은연,이상문,김수진,곽군평 國立 昌原大學校 產業技術硏究院 2004 産技硏論文集 Vol.18 No.-

The objective of this study is aimed at reducing the contour error of AC Servo derives by improving the interpolation error of each axis through sliding mode control system. The errors in machining process by AC Servo motor are due to many elements, such as the delay of the servo drivers, friction and the gain mismatch between x axis and y axis motors and so on. Sliding mode control system is applied to a AC servo drive as a numerical example in this paper. The experiment results which are compared with those of typical PI scheme show the validity of improvement in circular interpolation error of the system.

Cyclosulfamuron과 Pyribenzoxim의 莖葉處理에 따른 논 雜草 防除效果에 관한 硏究

金健敏,金武成,盧泳德 慶熙大學校 1997 論文集 Vol.26 No.-

Experiments were carried out to evaluate weed control performance of Cyclosulfamuron and Pyribenzoxim by foliar application, especially for direct seeded rice. In addition, the combinations of the herbicides and water managements were tested for the improvement of the herbicidal activity. Herbicidal effect of Cyclosulfamuron was excellent for B. tripartita, B, frondosa, fair or fairly good for A. indica, and C. cerotinus, and good for E. crus-galli, L. prostrata, S. juncoides, and A. keisak. Herbicidal effect of Pyribenzoxim was excellent for B. tripartita, B. fonndosa, A. keisak, and A. indica, fairly good for E. crus-galli, L. prostrata and poor for s. juncoides, and C. cerotinus. The foliar treatment of two herbicides were the most effective when irrigated 3 days after treatments. The herbicidal effects became poor when saturated condition was maintained, especially E. crus-galli and S. jucoides. Both Cyclosulfamuron and Pyribenzoxim were very effective for the control of B. tripartita and frondosa even under very low concentrations. But the higher rates of Pyribenzoxim are to be used for the better control of E. crus-galli and L. prostrata. Combination treatments of the two herbicides could extended the weed control spectrum. In addition the combination treatments had some positive effects in controlling L. prostrata, S. juncoides and A. keisak