NIKKEI 225 株價指數옵션의 스마일現象에 관한 實證硏究 : NIKKEI 225 주가지수옵션의 스마일현상에 관한 실증연구

김무성 釜山大學校 商科大學 2000 釜山商大論集 Vol.71 No.-

[김무성 새누리당 대표] 맞춤형 선별적 복지 더욱 강화해 나갈 것

김무성,이강덕(사회자),김민아(토론자),이도운(토론자),이동우(토론자),정용관(토론자) 관훈클럽 2016 관훈저널 Vol.- No.139

GaAs 집적회로 제조를 위한 에피 성장 연구

김무성,엄경숙,박용주,김용,김성일,조훈영,민석기,Kim, Moo-Sung,Eom, Kyung-Sook,Park, Young-Joo,Kim, Yong,Kim, Seong-Il,Cho, Hoon-Young,Min, Suk-Ki 한국재료학회 1993 한국재료학회지 Vol.3 No.6

Bulk반절연 기판 웨이퍼에 이온 주입법에 의한 기존의 GaAs집적회로 제작시 발생하는 문제점을 보완하고자 반절연 기판 위에 반절연성의 고저항 GaAs 에피층을 성장하는 연구를 수행하였다. 먼저 반절연 기판의 EPD분포를 조사하고, MOCVD와 MBE법을 이용하여 undeped GaAs반절연성 에피층을 성장시켜 실제 집적회로의 제작에 적합한지를 평가하였다. 평가방법은 반절연성 에피\ulcorner을 buffer층으로 성장시킨 에피 기판에 ungated FET를 제작하여, 이 반절연성 에피\ulcorner을 통한 누설전류를 측정하고, 또한 반절연 기판의 EP분호의 영향을 조사하였다. 누설 전류의 측정결과 비교적 주설 전류가 큰 1$\mu\textrm{m}$ 두께의 MOCVD시료에서도 270nA/mm로 FET의 pinch-off에는 영향을 주지 못하는 매우 작은 누설 전류 값을 나타내었다. 또한 누설전류의 분포가 반절연 기판의 EPD분포와 일치하는 것을 발견하여, 에피층의 quality에 기판의 결함이 미치는 영향을 확인하였다. MBE법으로 성장한 2$\mu\textrm{m}$ 두께의 undoped burrer층 시료는 휠씬 좋은 특성을 나타내었으며, 매우 균일하고 낮은 누설전류(40nA/mm)가 측정되었다. The growth of semi-insulating(SI) high resistant undoped GaAs epilayer has been studied to solve the problems ocurring when GaAs IC is fabricated by the widely used ion implantation directly into the SI GaAs substrate. The EPD ditribution of the SI substrates has been examined, and the suitability of the buffer layers grown by MOCVD and MBE, respectively, has been tested for IC fabrication through leakage current measurement. IJngated FET has been fabricated on the SI epilayer and leakage current through the buffer layer has been measured. In the case of MOCVD grown 1$\mu\textrm{m}$-thick buffer layer, the leakage current is as small as about 270nA/mm, and this value does not affect the pinch-off of FET. In this case, the epilayer quality is affected by the substrate defects because the leakage current distribution is coincided with the EPD distribution of the SI substrate. The 2$\mu\textrm{m}$-thick buffer layer grown by MBE, however, has the better quality, and shows the lower leakage current(40nA/mrn) and higher uniformity.

Brain-expressed X-linked 2 Binds to Kinesin Superfamily Protein 3A

김무성,정영주,박성우,서미경,김상진,이원희,엄상화,이정구,석대현 한국생명과학회 2022 생명과학회지 Vol.32 No.3

Kinesin-2 comprises two subfamilies of the heterotrimeric or homodimeric motors found in mammalian cells. Heterotrimeric kinesin-2 consists of kinesin superfamily proteins (KIFs) 3A and 3B and kinesin-associated protein 3 (KAP3), which is a molecular motor protein that moves along microtubules. It plays diverse roles in cargo transport, including anterograde trafficking in cilia, and interacts with many different cargoes and proteins, but their binding proteins have not yet been fully identified. In this study, the yeast two-hybrid assay was used to identify the proteins that interact with the cargo-binding domain (CBD) of KIF3A, and an interaction between KIF3A and brain expressed X-linked 2 (Bex2) was found. Bex2 bound to the CBD-containing C-terminal tail region of KIF3A but did not interact with the same region of KIF3B or KIF5A (a motor protein of kinesin-1). KIF3A interacted with another isoform, Bex1, but did not interact with Bex3. In addition, glutathione S-transferase (GST) pull-downs showed that KIF3A specifically interacts with GST-Bex1 and GST-Bex2 but not with GST alone. When co-expressed in HEK-293T cells, Bex2 co-localized with KIF3A and co-immunoprecipitated with KIF3A and KIF3B but not KIF5B. In combination, these results suggest that Bex2 is capable of binding to heterotrimeric kinesin-2 and may serve as an adaptor protein that links heterotrimeric kinesin-2 with cargo.

유기금속 화학 증착법

김무성 대한전자공학회 1987 전자공학회지 Vol.14 No.1

알팔파(Medicago sativa L.)밭 제초제의 잡초방제 효과

김무성,박태선,유환수 한국국제농업개발학회 2001 韓國國際農業開發學會誌 Vol.13 No.3

알팔파 재배시 제초제에 의한 잡초의 효율적인 방제대책을 강구하고자 잡초발생 양상과 함께 이들 잡초에 대한 방제효과 및 약해정도를 조사한 결과는 다음과 같다. 1. 알팔파 밭에서 발생되는 우점잡초로는 바랭이(Digitaria sanguinalis), 쇠비름(Portulaca oleracea), 석류풀(Mollugo strica), 방동산이가 가장 문제 초종이었다. 2. 처리된 제초제 모두 94.2% 이상의 높은 방제효과를 보였으나, alachlor 유제와 metachlor 유제는 석류풀 및 비름과 잡초들에 각각 비효과적이었으며, clomazone 입제와 trifluralin 유제는 방동산이에 낮은 방제효과를 보였다. 3. Alachlor 유제, metolachlor 유제 그리고 trifluralin 유제는 제초제 처리후 10일과 20일에 약해는 발생치 않았다. This experiment was conducted to investigate the weed control and phytotoxicity of herbicicides in the alfalfa(Medicago sativa L.) upland. The results obtained are as follows. The dominant weeds in the alfalfa upland were Digitaria sanguinalis, Portulaca oleracea, Mollugo strica and Cyperus microiroiria. Among those weeds, the most troublesome by dry weight was Digitaria sanguinalis. All herbicides applied in this experiment controlled more than 94.2% of total dry weight to weeds occurred in alfalfa upland. However, alachlor Ec. and metolachlor Ec failed to control Mollugo strica and Amaranthus weeds(Amaranthus lividus and Amaranthus retroflexus). Also, clomazone G and trifluralin Ec were non-effective to control of Cyperus microiroiria. Alachlor Ec, metolachlor Ec and trifluralin Ec exhibited normal growth of seedling at 10 and 20 days after treatment, but clomazone G and linuron Wp showed severe growth retardation of alfalfa seedling until 20 days after treatment. It was possible to safely use alachlor Ec, metolachlor Ec and trifluralin Ec if applied the rate of application tested in alfalfa upland.

신령버섯(Agaricus blazei Murill) 균사체내외 다당체의 면역활성효과

김무성,조홍범,Kim, Moo-Sung,Cho, Hong-Bum 한국미생물학회 2007 미생물학회지 Vol.43 No.4

신령버섯(Agaricus blazei Murill)의 액체 배양으로 다당체의 균사체외 분비를 유도하였으며, 버섯 균사체의 새포내 다당체와 세포외 분비 다당체의 면역증진활성을 in vitro 시험으로 비교하였다. 부분 정제된 세포내 다당체와 세포외 다당체의 총당 함량은 각각 85.6%와 95.3%였으며, ${\beta}$-glucan 함량은 각각 67.9%와 88.1%로 측정되었다. 면역활성 실험에는 시료의 닥 함량을 동일하게 맞추어 사용하였다. In vitro에서 균사체내외 다당체는 대식세포 주인 RAW 264.7을 활성화시켜 nitric oxide (NO) 생성을 농도 의존적으로 증가시켰으며, 각각 최대 53.9%, 53.1%의 비슷한 증가활성을 나타내었다. 또 균사채내외 다당체는 모두 RAW 264.7을 활성화시켜 염중성 cytokine류인 interleukin (IL)-$1{\beta}$, IL-6, tumor necrosis factor (TNF)-${\alpha}$의 생성을 증가시켰으며, 이때 3종의 cytokine 모두에서, 세포내 다당체에 비해 세포외 다당체를 처리했을때 저농도에서 높은 증가률을 나타내었다. 두 다당체는 in vitro 상에서 비장세포를 증식시키는 효과를 나타내었으며, 세포내 다당체가 농도 의존적으로 증식효과를 보인데 반해 세포외 다당체는 저농도에서 증식이 높았고, $250\;{\mu}g/ml$ 농도 이상에서는 더 높아지지 않았다. 두 다당체 모두 암세포인 B16F0 melanoma에 대한 직접적인 세포독성 효과는 나타내지 않았다. 신령버섯 균사체 배양으로 생성된 세포내외 다당체는 in vitro에서 모두 면역활성을 증가시키는 것으로 나타났으며 전반적으로 그 활성은 세포내 다당체보다 세포외 다당체가 우수한 것으로 판단되었다. This study was performed to compare in vitro immune enhancing effects of polysaccharides extracted from cultivated mycelia of Agaricus blazei Murill. Carbohydrate contents of semi-purified polysaccharides were 85.6% and 95.3%, while ${\beta}$-glucan conents were 67.9% and 88.1% for intracellular and extracellular polysaccharide, respectively. Samples were adjusted to the same in their carbohydrate contents before efficacy tests. Both intracellular and extracellular polysaccharide increased nitric oxide (NO) synthesis of macrophage RAW 264.7 in dose dependent manner, and the maximum increase rate was 53.9 and 53.1% in intracellular and extraceltular polysaccharide, respectively. The polysaccharides also increased synthesis of cytokines such as interleukin (IL)-$1{\beta}$, IL-6 and tumor necrosis factor (TNF)-${\alpha}$ in RAW 264.7. For all the 3 cytokines, the increase rate of synthesis was much higher in extracellular polysaccharide compared to intracellular polysaccharide, especially at low concentration. Both polysaccarides increased the proliferation of splenocytes in vitro, intracellular polysaccharide showed increase in dose dependent manner while extraceltular polysaccharide showed increase untill medium concentration ($250\;{\mu}g/ml$). They did not show direct cytotoxicity against cancer cells such as B16F0 melanoma. As results, it was regarded that the both intracellular and extracellular polysaccharide from A. blazei showed immune enhancing effects in vitro, but the activity is higher in extracellular polysaccharide compared to intracellular polysaccharide.

당화 최종산물(AGE) 생성 및 지질과산화에 대한 홍삼의 작용

김무성,임자혜 경기대학교 1999 論文集 Vol.43 No.2

Diabetes mellitus is postulated to be associated with increased lipid peroxidation, which may contribute to vascular complications. One potential mechanism of the increased lipid peroxidation in diabetes is lipid-linked advanced glycosylation and oxidation. Aminoguanidine, the prototype inhibitor of advanced glycosylation end product(AGE) formation, has been recently shown to prevent oxidative modification of LDL. To investigate whether Korean red ginseng, which is shown to have an antioxidative roles in several experimental systems, has an effect in ameliorating oxidative stress which increased in diabetes, we performed a preliminary in vitro study. Korean red ginseng was shown to be markedly effective in inhibiting AGE formation in this study of in vitro incubation. It prevented lipid peroxidation in both phospholipid liposome and LDL system as dose-dependent manner. At high concentration, red ginseng completely inhibited lipid peroxidation even after three hours of incubation in both systems. From the result of this study, it seems promising to pursue in vivo study of antioxidative roles of Korean red ginseng using experimental diabetic animal model.

High Density Array of Silver Accordion Utilizing Block Copolymer Confinement for SERS Substrate

김무성,하경원,김진곤 한국고분자학회 2017 한국고분자학회 학술대회 연구논문 초록집 Vol.42 No.1

飼料作物 Alfalfa(Medicago sativa L.)品種別 生育狀에 대하여

김무성,노영덕,김세영,백남인,정우진 경희대학교 부설 식량자원개발연구소 1996 硏究論文集 Vol.17 No.-

서로 특성이 다양한 32개의 도입한 Alfalfa품종을 우리나라 중부지역인 충청남도에 재배하여 초장과 건물중 등의 생육상태를 비교, 검토한 결과는 다음과 같다. 1. 평균초장이 큰 상위 10개 품종들은 Dekalb brand 135 > Diamond > Pioneer brand 581 > Raidor > Pioneer brand532 > Pierce> Nitro > Sparta ) Florida 77 > Sapphire의 품종순 이 며, 초장이 작은 10개 품종을 최하위 순으로 열거하여 보면 Salute < Spredor 2 < LS-1920 < Arrow < Challenger < Milkmaker < Armor < Pioneer brand 545 < Pioneer brand 5262 < Saranac의 품종 순이였다. 2. 총건물 수량이 많은 상위 10개 품종들은 Diamond > Nitro > Dekalb brand 120 > Dekalb brand 135 > Drummer > Saranac > Sapphire > Raider > Magnum > Dekalb brand 167의 품종 순이며, 건물수량이 적은 최하위 순으로 10개 품종은 Milkmaker < Pioneer brand 526 < Pioneer brand 5262 < Salute < Pioneer brand 555 < Decathlon < Pioneer brand 5929 < LS-1920 < Pioneer brand 581 < Husky의 품종들이였다. 3 평균초장과 총건물 수량의 결과를 비교하여 보면 대체로 초장이 우세하였거나, 열세하였던 품 종들이 다소간 건물수량이 우세하거나 열세하였으며, 정비례한 결과는 보이지 아니하였다. 4. 생육상태 및 건물수량이 모두 좋은 품종들은 Diamond, Nitro, Dekalb brand 135, Sapphire, Raidor품종들이며, 우리나라 중서부지역의 재배환경에 적합한 품종으로 사료된다 This study was conducted to select the best adapted alfalfa cultivars among the 32 introduced alfalfa cultivars with different characteristics in Chung-Chong Nam Do, Korea, environmental condition. Mean of plant height and total dry matter yields per cultivar from May to August in 1996 were determined. On the point of mean of plant height, ten high ranked cultivars among the 32 alfalfa cultivars in high order were Dekalb brand 135>Diamond>Pioneer brand 581>Raidor>Pioneer brand 532>Pierce>Nitro>Sparta>Florida 77>Sapphire and ten low ranked cultivars in low order were Salute<Spredor 2<LS-1920<Arrow<Challenger<Milkmaker<Armor<Pioneer brand 545<Pioneer brand 5262<Saranac. Ten high ranked cultivars from 32 alfalfa cultivars on the total dry matter yields in high order were Diamond>Nitro>Dekalb brand 120>Dekalb brand 135>Drummor>Saranac>Sapphire>Raidor>Magnum>Dekalb brand 167 and ten low ranked cultivars in low order were Milkmaker<Pioneer brand 526<Pioneer brand 5262<Salute<Pioneer brand 555<Decathlon<Pioneer brand 5929<LS-1920<Pioneer brand 581<Husky. Total dry matter yields of per cultivar was also slightly greater but It was not appeared direct proportion when alfalfa cultivar was appeared higher mean of plant height compared with those which were lower mean of plant height. Leading alfalfa cultivars for plant growth and dry matter yields were Diamond, Nitro, Dekalb brand 135, Sapphire, Raidor cultivar which can be well grown under moderate temperatures zone of midwest in Korea.