서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

초소형 마이크로 부품 표면 측정 시스템 개발

홍성욱,고명준,신영현,이득우 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

This paper proposes a measurement method for the surface of micro-parts by using AFM(Atomic Force Microscope). To this end, two techniques are presented to extend the capacity of AFM. First, the measurement range is extended by using an image matching method based on correlation coefficients. To account for the inaccuracy of the coarse stage implemented in AFM's, the image matching technique is applied to two neighboring images intentionally overlapped with each other. Second, a method to measure the shape of relatively large specimen is presented by using the inherent trigger mechanism due to the atomic force. The proposed method is proved effective through a series of experiments.

SMS를 이용한 경안천 하류구간의 하천흐름 분석

홍성민,정인균,이준우,김성준 한국지리정보학회 2004 한국지리정보학회지 Vol.7 No.1

본 연구는 경안천 하류구간(13.8㎞)을 대상으로 SMS의 RMA2 모형과 SES2D 모형을 이용하여 2002년 경안관측소의 최대홍수위를 기록한 8월 7일의 수리분석을 실시하였다. RMA2 모형을 적용하기 위하여 RIMGIS 데이터의 하천측량자료를 이용하여 입력자료로 활용하였으며, 생성돈 지형자료를 2차원 유한요소망으로 변환하여 모형을 수행하였다. 본 연구에서는 부정류 상태의 모의를 적용하였으며, 모형에 민감하게 반응하는 인자에 대해서는 선행 연구에서 실시한 민감도 분석결과를 고려하였고, 기타 입력인자는 통계연보 및 하천정비계획서를 참고하였다. 또한 대상하천에 SED2D 모형을 적용하여 홍수사상에 대한 하천의 하상 변동에 대한 모의를 실시하였으며, 대상 하천의 홍수시 유속은 0.05~3.85㎧의 분포로 상류와 하류의 큰 차이를 보였고, 하상변화는 0.0003~0.0135m가 발생하였다. The purpose of this study is to analyze various hydraulic characteristics using SMS(Surface Water Modeling System) RMA2 model. It is based on 2-D finite element method, River reaches (13.8㎞) from Gyeongan gauge station to the inlet of Paldang lake was selected. Finite element was made by RINGIS Data, and the analysis of river-changes was operated by unsteady flow. The sediment concentration and bed change was simulated using SED2D model. This River's velocity was distributed that 0.05~3.85㎧ and bed change was changed about 0.0003~0.0135m.

Euclid의 평행선 공준과 동치인 명제들

홍우철,홍성관 부산대학교 사범대학 2001 교사교육연구 Vol.40 No.-

In this paper we classify statements equivalent to Euclid's parallel postulate that appears in junior and senior high school math0texts, and give new proofs of them at the level of high school mathematics.

유럽건축가들의 역사적 건물 보전복구에 관한 연구

홍성우,이두진,이명권 경운대학교 산업기술연구소 2001 産業技術硏究論文誌 Vol.3 No.2(B)

The issue of historic preservation and restoration held no interests for the architects who pioneered and developed the modern movement. To them, the architectural theory of the modern movement was useful precisely because it helped them to break free of the historical past and the theoretical tradition of earlier architecture. In our own time, however, historic preservation has become multifaceted and the area of its involvement is constantly changed, and it has assumed almost as great an urgency as the continued development of modernity. As it has broadened its areas of activity and architect has played an important role in shaping the past and present of historic preservation and restoration, preservation research should focus its priorities and understand the limits of its resources in historic preservation and restoration process. In this study, therefore, the preservation and restoration principle of the 19th century European architects which were the main stream of historic preservation and restoration movement, was investigated from comparing there works and theories.

관해된 정신분열병과 양극성장애 환자의 언어성 기억 및 학습 기능 비교

우종민,정성심,정인원,김이영,이동수,홍경수 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.4

연구목적 : 본 연구는 관해 상태에 있는 정신분열병과 양극성장애 환자의 언어성 기억 및 학습 기능을 평가하고 이를 정상대조군과 비교하여 기억 요소의 질환별 특성을 분석하고자 실시하였다. 방 법 : 관해상태의 정신분열병 환자 30명과 양극성장애 환자 28명 및 정상대조군 72명을 대상으로 성, 연령, 교육연한, 발병연령, 잔여증상, 추체외로증상, 단순주의력 수준을 통제한 후 한글언어청각학습검사를 실시하여, 초과용량 즉각기억, 기억의 등록, 유지, 인출, 재인, 학습전략, 간섭효과를 분석하였다. 결 과 : 한글언어청각학습검사 결과를 세 집단간 비교한 결과, 정신분열병은 전행성 간섭효과를 제외한 모든 항목에서 대조군보다 유의하게 저하된 기억 수행을 보였으며, 양극성장애에 비해서도 대부분의 회상 시도에서 유의한 저하를 보였다. 특징적으로 학습 전략 활용 능력이 저조하였다. 양극성장애는 대조군에비해 즉각기억, 재인,학습전략에서 유의한 차이를 보이지 않았으나, 반복에 따른 회상과 학습은 대조군에 비해 유의하게 저하되었다. 정신분열병에 비해서는 전반적으로 비슷하거나 우월했지만, 간접자극 제시에 의한 회상 저하는 세 집단 중 가장 크게 나타났다. 환자군에서 검사성적에 대한 임상적 특성의 설명력을 분석한 결과, 정신분열병에서는 BPRS의 무력증 소척도, 유병기간, 입원횟수 등이 유의한 설명력을 갖는 것으로 나타났고, 양극성장애에서는 우울삽화 횟수가 유의한 설명력을 갖는 것으로 나타났다. 결 론 : 관해상태의 양극성장애와 정신분열병 모두에서 대조군과 구별되는 언어성 기억 및 학습 기능 저하가 관찰되었다. 이러한 기억 및 학습 기능의 결함은 이들 두 장애의 고유한 질병 특성 표지자일 가능성이 높으며, 향후 이들 질환의 병태생리를 이해하고 치료적 접근 방법을 모색하는 데에 단초가 될 수 있을 것이다. Objectives : This study was to investigate the verbal memory and learning ability in remitted schizophrenic patients and euthymic bipolar patients in order to explore trait-dependent cognitive deficits of each disorder. Methods : Verbal memory was assessed with KAVLT(the Korean version of Rey Auditory Verbal Learning Test) in outpatients with remitted schizophrenia(N=30), euthmic bipolar disorder(N=28), and normal control(N=72), KAVLT is made for assessment of immediate supraspan memory, registration, retention, retrieval, recognition, learning strategy, and interference effect. Several confounding factors including age, sex, educational level, attention span, residual psychopathology, and extrapyramidal symptoms were controlled among 3 groups. Patient groups were matched according to the age of onset, duration of illness, and frequency of hospitalization. Results : 1) The performance of bipolar group generally fall between the performance of schizophrenia and normal controls, while being most impaired in retroactive interference. Schizophrenic group showed significant impairment on most variables of KAVLT in comparison with the groups of bipolar disorder and normal control. 2) Within group analysis revealed that residual negative symptoms, duration of illness, and number of admission were highly correlated with the impairment of verbal memory and learning in schizophrenics. Number of depressive episodes and age were negatively correlated with verbal memory and learning among bipolar disorder patients. Conclusions : Both remitted schizophrenia and euthymic bipolar patients showed distinctive impairment in verbal memory and learning compared with controls. These results suggest that apecific impairment of verbal memory and learning in remitted state can be trait-dependent marker in both diseases. These deficits can give clues to the understanding of the pathophysiology and searching for more appropriate therapeutic interventions of mental disorders to improve cognitive deficits in remitted patients.

글루콘산 생산을 위한 최적 배양조건

홍성란,이현절,정봉우,김춘영 全北大學校 1995 論文集 Vol.39 No.-

The production of gluconic acid by Aspergillus niger KCTC 2119 was studied. The Optimal culture conditions, such as initial pH, temperature, inoculum size and medium composition were established. Maximum overall gluconic acid productivity, 0.13g/L · hr was obtained when the cultivation was carried out at 33℃ and initial pH 5.5 for 72 hrs, with medium containing 110g/L glucose, 0.5g/L (NH_4)_2SO_4, 0.2g/L KH_2PO_4, 1.0g/L MgSO_4·7H_2O, and 0.1g/L corn steep liquor. The metabolic parameters such as specific growth rate, cell and gluconic acid yields were estimated for process improvement.

프랑스 고딕건축의 네이브 벽체입면발전에 관한 연구

홍성우 대한건축학회 2003 대한건축학회논문집 Vol.19 No.4

The gothic architectural style emerged in the end of the twelfth century had pursued the monumental lightweight structure profoundly different from its antecedents. As every age of architecture evolved out of the previous style, however, gothic architecture also had developed from Late Romanesque and Early Gothic to High Gothic architecture. The evolution of gothic architecture through this process manifests in the interior wall elevation rather than the exterior. Thus, this study examined the transition of the nave wall elevation from Early Gothic to the High Gothic Cathedrals in Ile-de-France. As the result, three-story elevations, quadripartite vault and compound pier complete the development of the nave wall elevation.

Oil Contents and Fatty Acid Composition of Korean Perilla (Perilla ocimoides L.) Collections

Hong,Seong-Taek,Son,Suk-Yeong,Jong,Seung-keun,Rho,Chang-Woo,Yun,Jong-Sun 한국자원식물학회 2003 Plant Resources Vol.6 No.3

This study was carried out to obtain informations on the variations of oil content and fatty acid composition among 90 Korean perilla collections. Average oil content of 90 perilla collections was 44.2% with a range from 29.7% to 61.9%. Perilla collections with late-maturing, super-large seed and gray seed coat showed higher oil content than other types in general. Average saturated fatty acid content in perilla oil was 9.0% with a range from 8.2% to 10.7%, while average unsaturated fatty acid content varied from 89.3% to 91.8% with a mean of 91.0%. Contents of saturated and unsaturated fatty acids were not related to maturity. There were no differences in the contents of saturated and unsaturated fatty acids according to maturity. Linoleic acid and linolenic acid contents were the highest in the super large-sized group(15.5%) and in the large-sized seed group(61.4%), respectively, while contents of fatty acids among the perilla collections were variable with different seed coat colors. Most of the traits studied were not significantly correlated with oil content, but linoleic acid($\omega$ 수식 이미지-6) content was negatively correlated (r=-0.217*) with linolenic acid(ω-3) content.

赤芍藥 藥鍼이 白鼠의 抗血栓 效果에 미치는 影響

洪儒聖,黃祐準 한국전통의학연구소 1998 한국전통의학지 Vol.8 No.2

This study was performed to prove the antithrombotic effects of paeonia japonica(赤芍葯, PJ) aqua-acupuncture solution by way of experimental methods. the thrombosis was induced by injection of collagen the mixture (0.1ml/10g, 2mg/kg B.W) plus serotonin (5mg/kg B.W) into the caudal vein of rats, 2 hours after liquid extract of paeonia japonica(PJ) was acupunctured into 'Taechung'(太衝:Liv3) of rats. The effect of aqua-acupunctures of paeonia japonica(PJ) was examined by the number of RBC and platelets, bleeding time, blood clotting time, death rate, platelet aggregation, plasma coagulation factor activity, exvivo and vitro fibrinolytic activity of englobulin fracture in the rats. The results were summerized as followings. 1. The number of RBC and platelets was significantly increased in PJ-treated group in comparison with the control group. 2. Bleeding time was significantly shortened in PJ-treated group in comparison with the control group. 3. Blood clotting time was significantly prolonged in PJ-treated group in comparison with the control group. 4. The death rate of mouse was inhibited in PJ-treated group in comparison with the control group. 5. The platelet aggregation was inhibited in PJ-treated group in comparison with the control group. 6. The prothrombin time and activated partial thromboplastin time on the test of plasma coagulation factor activity was prolonged but was not valuable in PJ-treated group. 7. Fibrinogen lyses time of rat was reduced and lyses area was increased in PJ-treated group in comparison with the control group. 8. Fibrinogen lyses time of rat in vitro assay was reduced in PJ-treated group. From the above results, it was thought that the aqua-acupuncture of PJ could be applied effectively in the thrombosis.