서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1997)

김재홍,문득곤,김정수,김용준,임동진,박상훈,김희성,이민수,송기훈,김갑형,김형석,성소영,이인섭,김석우,황지환,조창근,김경문,부태성 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.3

Background : In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. Objective & Methods : For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1997. 99 strains of N. gonorrhoeae were isolated, among which 45(45.5%) were PPNG. Conclusion : The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 45.5% in 1997.

흰쥐에서 간담관 장애가 신장에 미치는 초미세 형태학적 연구

김용임,김일,이길부,최종범,기근홍,김용일,서재홍 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.16 No.1

It has been well-known that biliary cirrhosis with concomittant impairment of renal functions were occured after prolonged obstruction of biliary tract. In the present study, an attempt was made to investigate the mechanism of impaired renal function and the ultrastructural change of the kidney in rats, ligated the common bile duct for 21, 28 and 50 days in order to induce secondary biliary cirrhosis. The results obtained were as follows ; 1. Secondary biliary cirrhosis was produced evidently 28 days after ligation of common bile duct. Prominent proliferations of bile ducts and chronic inflammatory cell infiltrations were seen in pehportal area. 2. 28 and 50 days after ligation of common bile duct, show swelling and degeneration of mitochondria, microcystic formation and lysis of endoplasmic reticulum in the hepatocytes. Loss of microvilli in the bile ductules were noted. 3. Focal fusions, edema and bleb formations of foot processes were seen. Electron dense materials with variable size and global shape were found in foot process, 21, 28 and 50 days after ligation of common bile duct. 4. There were slightly thickening of renal glomerular basement membrane with hump in the subendothelial and widening of the mesangial matrix, 28 days after ligation of common bile duct. 5. There were moderately thickening of renal glomerular basement membrane and widening of the mesangial matrix with electron dense deposits, 50 days after ligation of common bile duct. From the above findings of electron microscopy, this study revealed electron dense deposits on renal glomerular mesangium of the rats as a results of experimental secondary biliary cirrhosis by ligation of common bile duct. Also severe hepatic injury due to swelling or lysis of rough endoplasmic reticulum and destruction of bile ductules resulted in deposited electron dense materials due to inhibition of excretion of immune complex through hepatobiliary tract, therefore this change indicated that immuncomplex could be deposited on renal glomerular mesangium.

ATHB12, an ABA-lnducible Homeodomain-Leucine Zipper (HD-Zip) Protein of Arabidopsis, Negatively Regulates the Growth of the Inflorescence Stem by Decreasing the Expression of a Gibberellin 20-Oxidase Gene

Ora Son,허윤선,김윤경,이현정,김성한,김미란,남경희,이명석,김부용,박종범,박정안,이석찬,Atsushi Hanada,Shinjiro Yamaguchi,이인정,김승기,윤대진,Eva So¨derman,천충일 Sookmyung Women's University Research Institute of 2010 여성과 건강 Vol.6 No.1

ATHB12, an ABA-lnducible Homeodomain-Leucine Zipper (HD-Zip) Protein of Arabidopsis, Negatively Regulates the Growth of the Inflorescence Stem by Decreasing the Expression of a Gibberellin 20-Oxidase Gene

Ora Son,허윤선,김윤경,이현정,김성한,김미란,남경희,이명석,김부용,박종범,박정안,이석찬,Atsushi Hanada,Shinjiro Yamaguchi,이인정,김승기,윤대진,Eva So¨derman,천충일 Sookmyung Women's University Research Institute of 2010 여성과 건강 Vol.6 No.1

회귀이상점 식별 알고리즘의 계산효율성과 정확성의 개선에 관한 연구

김부용,김새봄 숙명여자대학교 자연과학연구소 1997 자연과학논문집 Vol.- No.8

Hadi와 Simonoff(1993)가 제안한 회귀이상점 식별방법은 자료에 이상점이 다수 포함된 경우에도 이상점들을 효과적으로 식별할 수 있는 것으로 알려졌다. 그러나 식별 알고리즘의 미 단계에서 유사한 진단치를 반복적으로 계산하여 이를 바탕으로 이상점을 식별하기 위한 검정을 하므로 이에 요구되는 계산의 양이 매우 방대하다. 각 반복단계에서 기본부분집합이나 깨끗한 부분집합의 구성 형태를 분석한 결과, 소수의 관찰치만 변동되며 특히 하나의 관찰치만이 새로운 부분집합에 추가되는 경우가 많다는 사실을 확인하였다. 따라서 최신화 기법을 적용하여 필요한 계산을 효율적으로 실행할 수 있는 방법을 제안하였으며, 모의실험을 통하여 제안된 방법의 계산효율성이 우수함을 입증하였다. 한편, 구성된 부분집합의 자료는 악조건상태의 행렬인 경우가 많으므로 수치안정성에 문제가 발생하여 계산의 정확성이 낮아진다. 따라서 QR분해기법에 의해 진단치들을 계산하는 방안을 강구하였으며, 나아가서 계산의 정확성을 높이기 위해 반복 정제기법의 적용을 제안하였다. We investigate a procedure proposed by Hadi and Simonoff(1993) for the identification of multiple outliers in linear regression. The procedure is effective in the detection of multiple outliers, does not require presetting the number of outliers, does not require Monte Carlo simulation to determine cutoff values, and is relatively resistant to masking and swamping problems. However, it requires a great deal of computation since the diagnostics should be computed at each iteration. We have found that a small number of observations are changed, and at many iterations only one observation is added to the basic or clean subsets. Thus, to improve its computational efficiency, we propose an updating technique which can be applied to the computation of hat matrix, estimate of regression coefficients, residuals, and estimate of variances. Also the performance of the proposed technique is compared with that of the existing computing method on the basis of real and simulated data sets. It appears, from the Monte Carlo experiments, that the proposed technique is more computationally efficient than the existing one. On the other hand, since subsets constructed at each iteration are usually ill-conditioned, the numerical instability problem occurs and hence provokes inaccurate computations. Thus, QR-decomposition approach is employed to deal with the numerical instability problem, and the iterative refinement technique is used to obtain more accurate diagnostics.

선회류 유동층 소각로를 이용한 폐백토 소각

김부영,신용섭 慶星大學校 環境問題硏究所 1994 環境硏報 Vol.4 No.1

The fluidized bed incinerator has been successfully applied to solid waste incineration. However, in case of high volatile solid waste, for example mixture of waste oil and porous solid wasre, for example mixture of waste oil and porous solid waste, fluidized bed incinerator could not provide sufficient residence time for complete comvustion of gasified volatile matter. Thus, itis aim of this study to indentify the applicabiliy of the swirl-flow fluidized bed incinerator to incineration of high volatile solid waste which contains large amount of waste oil and porous solid material. From the experiment. it was found that combustion efficiency weakly denpended on air-fuel ratio and bed temperature and showed maximum value in the rangle of primary superficial air velocity from 0.2 m/s to 0.3 m/s. From the measured temperature distributions, there exited an active combustion region is the freeboard and this region moved up as the primary superficial air velocity increased. Concentrations of SO₂and NOⅹ showed negligible values throughout the whole rage of the experiment but CO concentration showed minimum value in the range of primary superficial velocity from 0.2 m/s to 0.3 m/s.

컨조인트분석에서의 선호도 조사방법 비교연구

김부용,신금희 숙명여자대학교 자연과학연구소 2002 자연과학논문집 Vol.- No.13

제품이나 서비스에 대한 소비자의 선호도에 영향을 미치는 속성들의 중요도를 파악하고 각 제품프로파일의 선호도를 예측하기 위하여 컨조인트분석이 사용되는데, 제품 포지셔닝이나 신제품 개발 분야에 이 분석이 많이 활용되고 있다. 본 논문에서는 휴대전화기의 선호도를 조사하여 컨조인트분석을 실시하였는데 동영상 내려받기 기능이 가장 중요도가 높았으며 휴대전화기 크기에 대한 중요도가 가장 낮았다. 제품선호도를 순위로 조사한 경우와 점수로 조사한 경우의 부분가치는 색상의 경우를 제외하고 동일한 크기 순서로 추정되었다. 한편, 선호도 조사방법별로 타당성을 측정하여 비교하였는데, 조사방법에 따른 타당성의 차이가 유의적이지 않은 것으로 나타났다. Conjoint analysis is employed to decompose the consumer's preference judgements into the importance of attributes, and to predict the degree of preference for each profile of the product or service. It has been widely used in industrial marketing, particularly in the areas of product positioning and new product development. A case study is performed on the preference for cellular phones. And it is shown that conjoint analysis based on the least squares estimator does not yield significantly different results with respect to the response methods.

로버스트 능형회귀 추정법

김부용,박형숙 숙명여자대학교 자연과학연구소 1999 자연과학논문집 Vol.- No.10

회귀분석을 위한 자료에는 회귀이상점이 포함되어 있으며, 동시에 다중공선성이 존재하는 경우가 있다. 이상점들만 포함되어 있는 경우에는 로버스트 추정법을 적용할 수 있으며, 다중공선성만 존재하는 경우에는 능형회귀 추정법을 적용할 수 있다. 그러나 회귀이상점과 다중공선성은 상호 관련을 가지므로 어느 한 문제만을 해결하는 것은 완전한 것일 수가 없다. 따라서 회귀이상점과 다중공선성이 동시에 존재하는 상황에서의 효과적인 추정 방법을 제안하고자 한다. Statisticians have suggested many methods for the problems of multicollinearity and outliers seperately. However, we usually encounter many data sets which have both problems. Thus, we propose a procedure that is called the robust ridge estimation and is very effective to deal with the problems simultaneously. The proposed procedure employs the LMS estimate to determine the bias parameter of ridge regression. In addition, it is verified by simulation studies that the proposed iterative method is more effective, in terms of the stability of estimates and squared distances, than the existing procedure based on the least squares estimates.

장애,비장애인 휠체어 농구선수의 유산소 능력

김성수,이동희,황부근,신말순,배종진,윤진환,지용석,안희구 한국특수체육학회 2002 한국특수체육학회지 Vol.10 No.2

The purpose of this study was to analyzed the aerobic capacity of disability· able-bodied wheelchair basketball players. Cardiorespiratory parameters were measured during graded maximal exercise test. Exercise time, HRpeak, oxygen uptake(VO_2, L·min^-1, ml·min^-1·kg^-1), carbon dioxide production(VCO_2, L·min^-1), ventilation(L·min^-1) were examined in disability national elite male wheelchair basketball at letes(DA, N = 10), able-bodied wheelchair basketball athletes(AA, N = 10). All data were expressed in means and standard deviation. Exercise time, HRpeak, oxygen uptake, carbon dioxide production, ventilation were not different between groups. In conclusion, aerobic capacity of disability national elite male wheelchair basketball athletes is the same able-bodied wheelchair basketball athletes. These finding suggest that chronic wheelchair basketball training produce local adaptations in the functional upper body musculature.