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Background and Objectives: Correlation of cyclin E, bcl-2, p27, VEGF, p53 and E-cadherin expression was analyzed in cervical intraepithelial neoplasia (CIN), carcinoma in situ (CIS), and microinvasive and invasive squamous cell carcinoma (SCC) according to human papilloma virus (HPV) inffection. Materials and Methods : (23 CIN 1, 28 CIN 2, 23 CIN 3), 18 CIS, and 24 SCC. Results: Expression of cyclin E was significantly higher in CIN 2, CIN 3, CIS and SCC than CIN 1 with or without HPV infection. Expression of bcl-2 was significantly higher in CIN 3 than SCC. There was no association between expression of p27 and VEGF and progression of CIN 1 to SCC. Expression of p53 was significantly high in CIN 3, CIS and SCC with or without HPV infection. Expression of the E-cadherin was significantly high in CIN 2, CIN 3, CIS and SCC with or without HPV infection. Conclusion: There was correlation between expression of cyclin E, b치-2, ㅔ53, E-cadherin and progression of CIN to SCC. It is suggested that cyclin E may play an important role in the neoplastic transformation of cervical squamous cell.
In gastric carcinomas including 20 cases of intestinal type and 20 cases of diffuse type, in adenoma (10 cases), and in metaplastic gastritis(10 cases), the presence of lactoferrin was investigated by immunohistochemistry. An evident reactivity for lactoferhn was encountered in intestinal type carcinomas, adenomas, and incomplete intestinal metaplasia. The problems in identifyng the steps in the pathogenesis of gastric cancer and in the calssification of its preneoplastic lesions led to a throughout analysis of the morphologic features of metaplastic gastritis, adenoma and adenocarcinoma of the gastric mucosa. Recently, several morphologic features with possible diagnostic significance have been identified among these parameters, several cytologic features seem to be of major importance for the quantitative analysis of the stepwise develop merit of malignancy. We have chosen to study nuclear and cytoplasm measurements as seen in gastric biopsied specimens. The results obtained were as follow: 1) Incomplete intestinal metaplasia, adenoma and intestinal type adenocarcinoma were stained with lactoferrin 2) Nuclear and cytoplasmic areas of incomplete metaplasia (50±14㎛_(2), 147±38㎛_(2)), Adenoma (56±16㎛_(2), 149±44㎛_(2)), Well differentiated adenocarcinoma(57±16㎛_(2), 152±48㎛_(2)), Moderate differentiated adenocarcinoma (44±14㎛_(2), 118±33㎛_(2)), Poor differentiated adenocarcinoma (54±16㎛_(2), 97±30㎛_(2)) and diffuse type adenocarcinoma (33±10㎛_(2) 434±124㎛_(2)) were noted. 3) Nuclear and cytoplasmic ratio of incomplete metaplasia(0.34±0.02), adenoma (0.38±0.02), well differentiated adenocarcinoma( 0.38±0.02), moderately differentiated adenocardnoma (0.37±0.02), Poor differentiated adenocarcinoma(0.56±0.01), and diffuse type adenocarcmoma (0.08±0.02) were noted.
The element reduction of a multiset S is to reduce the number of repetitions of an element in S by a predetermined number. Privacy-preserving element reduction of a multiset is an important tool in private computation over multisets. It can be used by itself or by combination with other private set operations. Recently, an efficient privacy-preserving element reduction method was proposed by Kissner and Song . In this paper, we point out a mathematical flaw in their polynomial representation that is used for the element reduction protocol and provide its correction. Also we modify their over-threshold set-operation protocol, using an element reduction with the corrected representation, which is used to output the elements that appear over the predetermined threshold number of times in the multiset resulting from other privacy-preserving set operations.
In Ad Hoc Networks, a connection breaks due to the irregular movement of mobile nodes and the inherent characteristics of the wireless medium such as the interference and the multi-path fading. AODV, a typical on-demand routing protocol in Ad Hoc networks, uses Destination sequence numbering for loop-free. but it may cause RREQ broadcast storm problem This paper proposes AODV_ods that does not need destination sequence number, in routing message and routing table without routing loop. To show the effectiveness of the proposed scheme, we performed extensive simulation with NS-2. The simulation results show that the proposed ADOV_ods efficiently uses wireless bandwidth compare to the original AODV. Finally AODV_ods reduces the routing overhead, end to end delay and increases the overall packet delivery ratio.