활성탄에 의한 카페인 및 니코틴의 흡착특성

손진언,이성식,김달한,유명호,이만식 동아대학교 환경문제연구소 1994 硏究報告 Vol.17 No.1

Adsorption equilibrium and kinetics of Caffeine and Nicotine from aqueous solution on activated carbon were determined experimentally in a batch system. Then, the equilibrium data were expressed by the Freundlich type and the equilibrium constants were obtained. Diffusion coefficient were determined by comparing experimental decay curve with theoretical ones. Surface diffusion was consided to be dominant and the value of diffusion coefficient were depent of the amount adsorbed and the equilibrium concentration. Domestic activated carbon has nearly same amount of adsorption as imported activated carbon made by CALGON carbon Corp.

南部 畓地帶에서 發生하는 올챙이고랭이(Scirpus juncoides Roxb.)의 雜草生態的 硏究

許祥萬,金晋鎬,孫寶均 順天大學校 1984 論文集 Vol.3 No.1

This study on the occurrence, regeneration and reproduction of the problematic weed, Scirpus juncoides Roxb., in the paddy field in the southern area was carried on for 12 months in order to investigate the various adaptability. The results obtained are as follows: 1. In O₂condition, a slightly insufficient condition treated by 0.02mm polyethylene film was the most favorable for germination. 2. In temperature, the more favorable condition for the germination of S.juncoides Roxb. seed was 35℃, 30℃, 25℃ in order, and the emergence rate of their stumps was high from 20℃ to 30℃. 3. In light intensity, germinating rate of S.juncoides Roxb. seed was higher in shade conditions than in perfect exposure, and so was the emergence rate of stump. 4. In light quality, germinating rate of S.juncoides Roxb. seed was high in order of black, yellow, green, and colorless film, while the emergence rate of stump was high in green film treatment. 5. In hydrogen-ion concentration of soil, the most optimun pH value for germination was 5.7, while in the extemely acid and alkaline soil, the growth was checked after the sixth week. 6. The emergence rate of stump was high in order of 3g, 4g, 5g, 2g, 1g in stump weight. 7. Initial growth of S.juncoides Roxb. shoot at two weeks after its cutting depended on underground nutrition. 8. Regeneration vigour of S.juncoides Roxb. shoot became dull since a growth period, and only one cutting after 25, May was enough to control S.juncoides Roxb. 9. Cutting of S.juncoides Roxd. shoot in the lagvegetative period around the end of May did not affected its regrowth. 10. In soil moisture content, the number of flower-bud was more in 100% saturated condition than in 80% saturated. In the submergence condition, 2cm water flooded depth was the most favorable for flower-bud formation of S.juncoides Roxb. 11. There was no constant tendency in soil condition and poor aeration condition was well adapted to S.juncoides Roxb. 12. As the shade rate increased, the flower-bud formation of S.juncoides Roxb. was suppressed. 13. The flower-bud formation of S.juncoides Roxb. was increased in yellow polyethylene film treatment. 14. with the MPK fertilizer level increased, the number of flower-bud was rapidly increased.

한국인의 우울증 진단기준의 특성

장성만,손지훈,이준영,최지환,조성진,전홍진,함봉진,이동현,조맹제 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.5

목적 국내의 여러 역학 조사에 따르면 한국인은 서구에 비하여 우울증의 유병률이 낮은 것으로 보고되고 있다. 낮은 유병률에 대하여 서구에서 정의하는 우울증의 진단 기준이 한국인의 문화에 맞지 않다는 진단 기준의 오류를 제시하거나, 실제로 유병률이 낮다는 설명을 시도하기도 하였다. 본 연구는 DSM-IV에서 제시하는 우울증의 진단 기준에 대하여 한국인의 반응 특성을 알아보고자 한다. 방법 2001년 KECA 연구에 응답한 만 18세 이상 65세 미만의 6,275명을 대상으로 하였다. 한국어판 CIDI (K-CIDI)를 통해 정신장애의 이환을 진단하였으며, K-CIDI 내의 우울장애 진단 기준만을 추출하여 분석하였다. 분석은 문항반응이론(Item Response Theory)을 적용하였다. 결과 한국인에서 DSM-IV의 주요우울장애 진단 기준의 오류는 없었으나, 진단 기준의 역치는 높았다. 한국인이 호소하는 우울증상으로서 "피로감"과 "집중력 저하", "수면 변화"는 진단되는 우울증의 초기부터 잘 나타나는 증상 들이며, "정선운동변화", "죽음/자살사고", "무가치함/죄책감"은 보다 심한 우울증에서 잘 나타나는 증상들이었다. 결론 DSM-IV가 제시하는 주요우울장애 진단 기준은 한국인의 우울증을 평가하는 데 있어 타당하기는 하나, 진단 기준의 역치가 높다. 우울증의 중증도에 따라 호소하는 증상들이 달랐다. Baekgrounds : Many Korean epidemiologic studies reported lower prevalence rates of depression than those of Western countries. For the low prevalence, it is explained that there's something wrong in the direct application of diagnostic criteria of depression to Korean culture, i.e. categorical fallacy, or it may be truly low-prevalent. We will analyze diagnostic criteria for depression detined by Western. Methods : Six thousand and two hundred seventy-five cummunity dwelling subjects, aged 18-64 years were interviewed by using Korean version of Composite International Diagnostic Interview (K-CIDI). Diagnostic criteria for depression defined by DSM-IV were analyzed using the item response theory. Rcsults : We could not find any fallacies of diagnostic critcria tbr depression defined by DSM-IV when assessing depre-ssion among Koreans. Fatigue, concentration difficultics, and sleep disturbance appeared more fequently in mild depression, while psychomotor change, death/suicide, and worthlessness/guilt did not appear until severe depression. Cunclusion : The diagnostic criteria for depression defined by DSM-IV arc appropriate for the Koreans. There are different responding levels, i.e. threshold, of depressive criteria according to severities of depression. Koreans with depression are more likely to complain of appetite change, but less of worthless or guilty feelings than Western people.

대도시 청소년 체격의 발육발달과 표준체중에 관한 연구

김성만,손흥기,김복현 경희대학교 체육과학연구소 1995 體育學論文集 Vol.23 No.-

The Purpose of this study is to analyzing the developing process of physique during the 12 years regression equation standard body weight according to the age and body height and also we analyzed the distribution status of normal body weight and obesity weight in 17-year old high school students. A total of 1,423 samples(male:723, female: 701, born between March 1, 1977∼February 28, 1978) and the students who were randomly selected in big city of north of Jeola province, The result of our analysis are as follows: 1.Measurement of Physique ①The steady growth showen 14 year of male and 12-year of female in body height, 14-year of male and 13-year of female In body weight, 15-year of male and 13-year of female In chest-girth, since then the growth and development linear curve is more showness. ②During the 12year of school age, the rate of growth were 55.12cm(47.4%) of male 44.80cm(38.9%) of female in body height 43.59(214.5%) of male, 35.20kg(180.8%) female in body weight and 3.83cm (55.48%) of male, 28.11cm(50.70%) of female in chest girth. ③The age of maximum rapids growth were 12∼13 years old(7.36 ± 2.52cm) of male 10∼ 11years old (6.81± 1.88cm) of female In body height, 12∼13years old(6.14±3.37kg) of male, 11∼12 years old(5.49±2.67kg) in body weight and the chest-girth were 13∼14years old(4.34± 3.20cm) in male, 11∼12 years old(5.01 ± 3.80cm) in female. ④The age of cross over between male and female were 9.7∼ 11.7 years old in body height, 11.5∼ 13.5 years old in chest-girth and there is on cross over in body weight. ⑤The body height of 17-year old was 171.68∼5.56cm in mate and 159.92±4.85cm in female, body weight was 63.91±8.89kg in male and 54.67±6.74kg in female and the chest-girth was 89.20±5.94cm in male 83.55 ± 5.27cm in female. ⑥Physical growth and development was more remarkable improvement than 1980' Physique especially the age of adolescence. 2.Standard body weight by regression equation ①Correlation coefficient of r=0.469-0.760 between body height and body weight in male and r=0.347-0.793 in female. ②Regression equation of standard body weight were found in 17-year old and the equation were y =0.749X+64.791 in male, y=0.484X+22.800 in female. ③The distribution of normal body weight were 63.1% in male and 76.2% in female, over weight were 10.4% in male and 9.3% in female and the obesity weight were 6.9% in male and 3.4% in female.

임신중 알코올 섭취에 의한 기형 유발기전에 관한 연구

김소희,김순선,이규식,손경희,곽승준,채수영,안상미,허만욱,박귀례 식품의약품안전청 2001 식품의약품안전청 연보 Vol.5 No.-

임신중에 만성적으로 음주한 산모의 태아는 중추신경계 손상으로 인한 특징적인 이상증상인 소두증 정신발육장애 등 태아 알코을 증후군(fetal alcoho3 syndrome, F,LSB이 나타나는 것으로 알려져 있으냐 분자생물학적 측면에서의 유발기전은 명확하게 밝혀져 있지 않다. 든 연구예서는 in vitro 단기 발생독성시험법 중 하나인 전배자배양댑을 사용하여 랫드 배자의 )1관 발생기에 알코을 및 알코올의 주 군사 체인 아세트알데히드를 처리하여 기형 유발 여부를 관찰하였다. 또한 이들 물질의 기형 유발 기전을 규명하고자 microarray 깡법으로 발현이 변화되는 유전자를 검색하였으며, 알코을 처리로 발현이 변후 되는 유전자의 정확한 확인을 위하여 northern blot analysis 실시 중이다. 임신 9.5일의 랫드 배자에 0.1, 0.5, 1.0% 에란올을 처리하였을 때 성장부진, 뒤틀리거나 꼬렬라진 꼬리, open caudal neura tube, open neural tube, 불완전찬 반전, 불규칙적이고 비정상적인 체절과 짧은 꼬리 등의 이상이 나티났다. 임신 9.5일의 랫드 배자에 Sr10-4, 8.3×10-4, 2.SxIO-3% 아세트알데히드를 처리시 래antois caudal neura3 tube의 발달저해, somite 수 감소, 꺽인 꼬리 등의 이상이 나타났다. Control과 에탄을 처리한 배자로부터 total RNA를 추출하고 poll· A--RNA를 분리한 후, reverse transcriptase를 사용하여 C?3 혹은 Cl·5 형광염료로 tag된 nucleotide로 표지된 probe를 만들어 등량을 시판중인 'toxicotogy chip'의 틴991개의 CDNA 형태의 유전자와 hybr겨iaation시켰다. 에탄을 처리에 의해 'serum deprivation response' gene등의 발현이 유도되었으며, 'rat transcription factor MaflmRNA'등의 발현은 저해되었다. It is reported that alcohol drinking by pregnant mothers often leads to abnormal fetal development including fetal alcohol syndrome(FAS) in both humans and experimental animals. The FAS is characterized by prenatal and postnatal growth retardation, distinct craniofacial dysmorphology, and central nervous system dysfunctions such as mental retardation. However, molecular mechanisms for FAS is not completely elucidated as yet. In this study, developmental toxicity of ethanol and its metabolite, acetaldehyde were evaluated using whole embryo culture. In addition genes inducing FAS were investigated by the technique of cDNA microarray. Embryos treated with ethanol showed growth retardation, abnormal tail torsion, open neural tube, open caudal neural tube and abnormal somite at concentrations of 0.1∼0.5%. Also embryos treated with acetaldehyde showed growth retardation including allantois, open caudal neural tube, reduction number of somite and abnormal tail torsion at concertrations of 5×10^(-4)∼2.5×10^(-3)%. RNAs from embryos of control and ethanol treatment were reverse transcribed into cDNA tagged with Cy3 or Cy5 and hybridized with cDNA probe of rat in 'toxicology chip'. Ethanol 0.5% treatment resulted in alteration in expression of several genes including 'serum deprivation response', 'Cide-b' and 'check point suppressor 1'. Northern blot analysis is conducted for identification of genes related to FAS.

Development of Manufacturing Technology for Crash Energy Absorption Bumper Stay with Hydroforming

Sung-Man Sohn,Mun-Yong Lee,Bong-Joon Kim,Young-Hoon Moon 한국소성가공학회 2005 한국소성가공학회 컨퍼런스 Vol.2005 No.11

Microbleeds in Patients with Primary Intracerebral Hemorrhages

Kim, Il-Man,Yim, Man-Bin,Son, Eun-Ik,Sohn, Sung-Il,Sohn, Chul-Ho The Korean Neurosurgical Society 2006 Journal of Korean neurosurgical society Vol.39 No.3

Objective : We investigate risk factors of cerebral microbleeds[MBs] and their relation to concomitant magnetic resonance[MR] findings in intracerebral hemorrhages[ICHs] patients. Methods : We studied 100 consecutive patients with primary ICH over a 1-year period. These patients underwent brain MR images using 3.0-T scanners within the first week of the hemorrhage. MBs and old hematomas were located and counted by using $T2^*-weighted$ gradient-echo MR imaging. We also counted lacunes and graded white matter and periventricular hyperintensity on T1- and T2-weighted spin-echo sequences. The association between MBs and vascular risk factors and MR abnormalities were analyzed. Results : MBs were seen in 77 of ICH patients, and their number ranged from 1 to 65 lesions [mean 11, median 6]. The locations of MBs were subcortex-cortex [40.6%], basal ganglia [26.7%], thalamus [14.1 %], brain stem [12.5%], and cerebellum [9.1 %]. Analysis of clinical data revealed that age, hypertension, history of stroke, and duration of hypertension were frequently associated with MBs. The incidence of lacunes, old hematomas, and advanced leukoaraiosis was significantly higher in the MBs group, compared with the patients without MBs. Conclusion : MBs are frequently observed in ICH patients with advancing age, chronic hypertension, and previous hemorrhagic stroke, and are also closely related with morphological signs of occlusive type microangiopathy, such as lacunar infarct and severe leukoaraiosis.

GISTs에서 증가된 Ki67 Index (>10%)와 p53 단백발현의 예후 인자로서의 유용성

손보성(Bo Sung Sohn),전해명(Hae Myung Jeon),성기영(Gi Young Sung),진형민(Hyung Min Jin),김욱(Wook Kim),박조현(Cho Hyun Park),박승만(Seung Man Park),임근우(Keun Woo Lim),박우배(Woo Bae Park),김승남(Seung Nam Kim),이교영(Kyo Young Lee 대한외과학회 2004 Annals of Surgical Treatment and Research(ASRT) Vol.66 No.2

施設 裁培地에서 자란 가지와 고추에 있어서 VA菌根菌 感染에 관한 硏究

孫寶均,許祥萬 順天大學校 農業科學硏究所 1989 農業科學硏究 Vol.3 No.-

The infection levels of vesicular-arbuscular mycorrhizal(VAM) fungi in roots, the number of endogenous spores in different size and color under reflected light in rhizosphere soil of hot pepper and eggplant grown under the greenhouse conditions were investigated. The infection levels of hot pepper and eggplant were 53% and 45%, respectively. The number of VAM fungal spore was high level in the range from 106㎛ to 250㎛ for two host crops. The distribution of VAM spores in color under the reflected light was high in the range from reddish brown to black color in both hot pepper and eggplant. The VAM fungal endophytes penetrated the root through epidermal cells and then formed vesicles and arbuscules in cortical tissue. In case of hot pepper, the vesicles within roots were 32.5×90㎛ to 50×100㎛ in size, had various forms including elliptical, ovate and stick-shaped form. But arbuscules were rare. The vesicles in the root of eggplant were 30㎛ to 77.5㎛ in diameter and much arbuscules in them were observed. Vesicles observed were ovate and elliptical in shape, and they were mixed with arbuscules and difficult to distinguish. Around 5㎛ diameter-internal hyphae in the root samples of two host crops were common. Two species in Endogonales were identified; Acaulospora bireticulata, A.foveata.

Craniopharyngioma in the Temporal Lobe : A Case Report

Sohn, Chul-Ho,Baik, Seung Kug,Kim, Sang-Pyo,Kim, Il-Man,Sevick, Robert J. Korean Radiological Society 2004 Korean Journal of Radiology Vol.5 No.1