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Myxoid Chondrosarcoma of the Sinonasal Cavity in a Child: a Case Report
Kim, Yeo Ju,Im, Soo Ah,Lim, Gye-Yeon,Chun, Ho Jong,Park, Hyun Jin,Kim, Min Sik,Choi, Yeong Jin The Korean Radiological Society 2007 KOREAN JOURNAL OF RADIOLOGY Vol.8 No.5
<P><B/></P><P>Chondrosarcomas are malignant tumors of cartilage that rarely involve the sinonasal region, and myxoid chondrosarcoma is a rare histologic variant of chondrosarcoma that usually occurs in the soft tissue of extremities. Although several case reports and results of small series of chondrosarcomas in the sinonasal region in children are available, myxoid type chondrosarcoma is extremely rare. We recently experienced a case of low grade myxoid chondrosarcoma involving the sinonasal cavity in a 10-year-old boy, and here we report its radiologic-pathologic findings. In this case, chondroid calcification on CT and septal and marginal enhancement on MRI suggested a chondrosarcoma. Whole body PET-CT demonstrated no definite metastatic lesion and a low peak standardized uptake value primary tumor. However, no definite distinguishing imaging features were observed that distinguished low grade myxoid chondrosarcoma from conventional chondrosarcoma.</P>


Radiological Spectrum of Hepatic Mesenchymal Hamartoma in Children
Kim, Soung Hee,Kim, Woo Sun,Cheon, Jung-Eun,Yoon, Hye-Kyung,Kang, Gyeong Hoon,Kim, In-One,Yeon, Kyung Mo The Korean Radiological Society 2007 KOREAN JOURNAL OF RADIOLOGY Vol.8 No.6
<P><B>Objective</B></P><P>A hepatic mesenchymal hamartoma is an uncommon benign tumor in children and little is known about the spectrum of its radiological features. The purpose of this study is to describe the spectrum of radiological features of a hepatic mesenchymal hamartoma in children.</P><P><B>Materials and Methods</B></P><P>Thirteen children with a pathologically confirmed hepatic mesenchymal hamartoma (M:F = 7:6; mean age, 3 years 2 months) were included in our study. Ultrasonography (US) was performed in nine patients including color and power Doppler US (n = 7). CT scans were performed in all patients. We evaluated the imaging findings of the hepatic mesenchymal hamartomas and the corresponding pathological features.</P><P><B>Results</B></P><P>Each patient had a single tumor (mean diameter: 13 cm [1.8-20 cm]). On CT and/or US, four patients (31%) had a 'multiseptated cystic tumor', five patients (38%) had a 'mixed solid and cystic tumor', and four patients (31%) had a 'solid tumor.' The septa of the cystic portion were thin in the multiseptated cystic tumors and irregularly thick in the mixed solid and cystic tumors as seen on US. On a post-contrast CT scan, solid portions or thick septa of the tumors showed heterogeneous enhancement. The amount of hepatocytes was significantly different among the three tumor groups according to the imaging spectrum (<I>p</I> = 0.042).</P><P><B>Conclusion</B></P><P>A hepatic mesenchymal hamartoma in children can show a wide spectrum of radiological features, from a multiseptated cystic tumor to a mixed solid and cystic tumor, and even a solid tumor.</P>
Lee, Hyunjong,Lee, Won Woo,Park, So Yeon,Kim, Sang Eun Korean Radiological Society 2016 KOREAN JOURNAL OF RADIOLOGY Vol.17 No.2
<P>Objective: The aim of the study was to compare the diagnostic performances of F-18 sodium fluoride positron emission tomography/computed tomography (bone PET/CT) and bone scintigraphy (BS) for the detection of thyroid cancer bone metastasis. Materials and Methods: We retrospectively enrolled 6 thyroid cancer patients (age = 44.7 +/- 9.8 years, M:F = 1:5, papillary: follicular = 2: 4) with suspected bone metastatic lesions in the whole body iodine scintigraphy or BS, who subsequently underwent bone PET/CT. Pathologic diagnosis was conducted for 4 lesions of 4 patients. Results: Of the 17 suspected bone lesions, 10 were metastatic and 7 benign. Compared to BS, bone PET/CT exhibited superior sensitivity (10/10 = 100% vs. 2/10 = 20%, p = 0.008), and accuracy (14/17 = 82.4% vs. 7/17 = 41.2%, p < 0.025). The specificity (4/7 = 57.1%) of bone PET/CT was not significantly different from that of BS (5/7 = 71.4%, p > 0.05). Conclusion: Bone PET/CT may be more sensitive and accurate than BS for the detection of thyroid cancer bone metastasis.</P>


Lee, Sang Hoon,Suh, Jin-Suck,Shin, Myung Jin,Kim, Seong Moon,Kim, Namkug,Suh, Sang Hyun The Korean Radiological Society 2008 KOREAN JOURNAL OF RADIOLOGY Vol.9 No.1
<P><B>Objective</B></P><P>To validate contrast-enhanced power Doppler ultrasonography (PD US) for the evaluation of synovial vascularity in an arthritic rabbit knee model in correlation with MR and histological findings.</P><P><B>Materials and Methods</B></P><P>Power Doppler ultrasonography was performed for carrageenin-induced arthritic left knee and control right knee of 13 rabbits, first without and then with sonic contrast agent enhancement (Levovist, Schering, Berlin Germany), followed by gadolinium-enhanced MR imaging. Synovial vascularity was quantitatively assessed by calculating the color pixel area in power Doppler sonography using a computer-aided image analysis program and by grading the enhancement on MR images: grade 1, enhancement of knee joint is less than one-third of the area; grade 2, one-third to two-thirds enhancement; and grade 3, more than two-thirds enhancement. Microvessel density (MVD) was measured on slides stained immunohistochemically for CD31 antigen for histological assessment.</P><P><B>Results</B></P><P>The mean area of color pixels in PD US changed from 4.37 to 16.42 mm<SUP>2</SUP> in the arthritic knee after enhancement (<I>p</I> < 0.05), whereas it changed from 0.77 to 2.31 mm<SUP>2</SUP> in the control knee (<I>p</I> < 0.05). Arthritic knees had greater power Doppler signal than control knees both before and after contrast administration (<I>p</I> < 0.05). The average MVD was 88 in arthritic knees and 46 in control knees. MVDs correlated with color pixel areas of contrast-enhanced power Doppler imaging in arthritic knees. In MR grading of arthritic knees, five were grade 2 and eight were grade 3. MVD and PD US revealed no significant difference between grade 2 and 3 arthritic knees (<I>p</I> > 0.05).</P><P><B>Conclusion</B></P><P>Sonic contrast-enhanced PD US improves the visualization of synovial vascularity and allows quantitative measurement in experimentally induced rabbit arthritic knees.</P>
Lee, Deok Hee,Na, Dong Gyu,Ihn, Yon Kwon,Kim, Dong Joon,Kim, Eung Yeop,Kim, Yong Sun,Lim, Soo Mee,Roh, Hong Gee,Sohn, Chul-Ho The Korean Radiological Society 2007 KOREAN JOURNAL OF RADIOLOGY Vol.8 No.2
<P><B>Objective</B></P><P>The purpose of the study was to review the current status of intra-arterial (IA) thrombolysis in Korea by conducting a retrospective analysis of the data from multiple domestic centers.</P><P><B>Materials and Methods</B></P><P>The radiologists at each participating institution were asked to fill out case report forms on all patients who had undergone IA recanalization due to acute anterior circulation ischemia. These forms included clinical, imaging and procedure-related information. A central reader analyzed the CT/MR and angiographic results. The rates of successful recanalization, hemorrhagic transformation and functional outcome were obtained. The univariate analyses were performed together with the multivariate analysis.</P><P><B>Results</B></P><P>We analyzed the data from 163 patients, and they had been treated at seven institutes. The initial imaging modalities were CT for 46 patients (28%), MR for 63 (39%), and both for 54 (33%). Various mechanical treatment methods were applied together in 50% of the patients. Radiologically significant hemorrhage was noted in 20/155 patients (13%). We found various factors that influenced the recanalization rate and the occurrence of significant hemorrhagic transformations. The favorable outcome rate, reported as modified Rankin Scale ≤ 2, was 40%, and the mortality rate was 11%. The factors that predicted a poor functional outcome were old age (<I>p</I> = 0.01), initially severe neurological symptoms (<I>p</I> < 0.0001), MR findings of a wide distribution of lesions (<I>p</I> = 0.001), involvement of the basal ganglia (<I>p</I> = 0.01), performance of procedures after working hours (<I>p</I> = 0.01), failure of recanalization (<I>p</I> = 0.003), contrast extravasation after the procedure (<I>p</I> = 0.007) and significant hemorrhagic transformation (<I>p</I> = 0.002). The subsequent multivariate analysis failed to show any statistically significant variable.</P><P><B>Conclusion</B></P><P>There was a trend toward increased dependency on MR imaging during the initial evaluation and increased usage of combined pharmacologic/mechanical thrombolysis. The imaging and clinical outcome results of this study were comparable to those of the previous major thrombolytic trials.</P>


Kim, Suk Jung,Roh, Hong Gee,Jeon, Pyoung,Kim, Keon Ha,Lee, Kwang Ho,Byun, Hong Sik,Moon, Won-Jin,Kim, Gyeong-Moon,Kim, Young-Wook,Kim, Dong Ik The Korean Radiological Society 2007 KOREAN JOURNAL OF RADIOLOGY Vol.8 No.4
<P><B>Objective</B></P><P>The aim of this study was to examine the incidence of ischemia during protected carotid artery stenting (CAS) as well as to compare the protective efficacy of the balloon and filter devices on diffusion-weighted MR imaging (DWI).</P><P><B>Materials and Methods</B></P><P>Seventy-one consecutive protected CAS procedures in 70 patients with a severe (> 70%) or symptomatic moderate (> 50%) carotid artery stenosis were examined. A balloon device (PercuSurge GuardWire) and a filter device (FilterWire EX/EZ, Emboshield) was used in 33 cases (CAS-B group) and 38 cases (CAS-F group) to prevent distal embolization, respectively. All the patients underwent DWI within seven days before and after the procedures. The number of new cerebral ischemic lesions on the post-procedural DWI were counted and divided into ipsilateral and contralateral lesions according to the relationship with the stenting side.</P><P><B>Results</B></P><P>New cerebral ischemic lesions were detected in 13 (39.4%) out of the 33 CAS-Bs and in 15 (39.5%) out of the 38 CAS-Fs. The mean number of total, ipsilateral and contralateral new cerebral ischemic lesion was 2.39, 1.67 and 0.73 in the CAS-B group and 2.11, 1.32 and 0.79 in the CAS-F group, respectively. No statistical differences were found between the two groups (<I>p</I> = 0.96, 0.74 and 0.65, respectively). The embolic complications encountered included two retinal infarctions and one hemiparesis in the CAS-B group (9.09%), and one retinal infarction, one hemiparesis and one ataxia in the CAS-F group (7.89%). There was a similar incidence of embolic complications in the two groups (<I>p</I> = 1.00).</P><P><B>Conclusion</B></P><P>The type of distal protection device used such as a balloon and filter does not affect the incidence of cerebral embolization after protected CAS.</P>

