외이도 이물에 의한 경정맥구 손상 1예

박찬흠,소상훈,김형종,임현준 대한이비인후과학회 1999 대한이비인후과학회지 두경부외과학 Vol.42 No.9

임플란트의 collar design이 변연골과 연조직에 미치는 영향

유현상,강선녀,정창모,윤미정,허중보,전영찬 대한치과보철학회 2012 대한치과보철학회지 Vol.50 No.1

연구 목적: 임플란트 경부가 잘 설계된 경우 양호한 연조직 반응을 통해 변연골을 보존하는데 도움이 된다. 본 실험에서는 연, 경조직 경계부에 가장 가까이 위치하는 임플란트의 collar design이 변연골 변화와 연조직 반응에 미치는 영향을 동물실험을 통해 알아보고자 하였다. 연구 재료 및 방법: 2마리의 건강한 Beagle dog에 임플란트 collar design만 다른 두 종류의 임플란트(Neobiotech Co. Seoul, Korea)를 식립하였다. Collar에 bevel 을 부여한 군(Bevel 군)과 "S"자 형태를 부여한 군(Bioseal 군)으로 나누어 마리 당 7개, 군당 7개, 총 14개의 임플란트를 무작위로 식립한 후 Healing abutment를 즉시 체결하였다. 디지털 표준구내 방사선사진을 이용해 4주 간격으로 총 12주간 근원심 변연골 변화를 관찰하였고, 12주에 희생하여 조직학적 분석을 통해 협설 변연골 흡수 및 임플란트 주변 연조직 반응을 평가하였다. Mann-Whitney test를 통해 동일한 방사선 사진 촬영 시점에서 근원심 변연골 변화량 및 조직계측치를 군 간 비교하였고, Kruskal-Wallis test를 통해 방사선 사진상 근원심 변연골 변화량이 시간에 따른 차이가 있는지 군 내 분석 한 후 Duncan test를 통해 사후 검증하였다(α=.05). 결과: 방사선학적 분석 결과 각 촬영 시점에서 두 군간 근원심 변연골 변화량의 차이를 보이지 않았다(P>.05). 군 내에서 시간에 따른 근원심 변연골의 흡수량을 분석한 결과 Bevel 군에서는 시간에 따른 차이를 보이지 않았으나 (P>.05), Bioseal 군에서는 시간에 따른 차이를 보였으며, 4주및8주와 비교했을 때 12주에서 변연골의 증가를 보였다(P<.05). 조직학적 분석 결과 협설측 변연골 흡수량에서 두 군간 차이를 보이지 않았으나 (P>.05), Bevel 군에 비해 Bioseal 군에서 더 견고한 결합조직부착을 관찰할 수 있었으며, 생물학적 폭경의 값은 두 집단 간 차이를 보이지 않은 반면에 (P>.05), 접합상피부착은 Bevel 군에서 유의하게 길었고, 결합조직부착은 Bioseal 군에서 더 길게 나타났다(P<.05). 결론: Bevel 군에 비해 Bioseal 군에서 결합조직부착은 길게 형성된 반면에 접합상피부착은 더 짧게 나타났으며, 생물학적 폭경과 초기 변연골 흡수에는 차이가 없음을 알 수 있었다. 연조직 반응의 차이가 실제 기능하중 하에서 변연골 변화에 미치는 영향에 대해서 향후 연구가 필요할 것으로 생각된다. PURPOSE. The purpose of this study was to investigate the effects of implant collar design on marginal bone change and soft tissue response by an animal test. MATERIALS AND METHODS. Two types of Implant (Neobiotech Co. Seoul, Korea) that only differs in collar design were planted on two healthy Beagle dogs. The implants were divided into two groups, the first group with a beveled collar (Bevel Group) and the second group with "S" shaped collar (Bioseal group). Standardized intraoral radiographs were used to investigate the mesio-distal change of the marginal bone. Histological analysis was done to evaluate the bucco-lingual marginal bone resorption and the soft tissue response adjacent to the implant. Mann-Whitney test was done to compare the mesio-distal marginal bone change at equivalent time for taking the radiographs and the tissue measurements between the groups. RESULTS. Radiographic and histological analysis showed that there was no difference in marginal bone change between the two groups (P>.05). Histological analysis showed Bioseal group had more rigid connective tissue attachment than the Bevel group. There was no difference in biological width (P>.05). Bevel group showed significantly longer junctional epithelium attachment and Bioseal group showed longer connective tissue attachment (P<.05). CONCLUSION. For three months there were no differences in marginal bone change between the Bevel group and the Bioseal group. As for the soft tissue adjacent to the implant, Bioseal group showed longer connective tissue attachment while showing shorter junctional epithelium attachment. There were no differences in biologic width.

해수중 화학원소의 거동과 생물활동

현상민,최영찬 제주대학교 해양연구소 1997 해양자원연구소연구보고 Vol.21 No.-

The concordant variation between chemical elements and biological activity in seawater is reviewed in this paper. The flux of the biogenic components in seawater is highly linked up with the flux of the lithogenic materials or vise versa. indicating that suspended clays. fine fractions and chemical elements are efficiently scavenged through the water column by sinking organic aggregates. Most of chemical elements in seawater are formed as complexation. suggesting that the biological activity in seawater plays an important role in becoming a complex form of chemical elements. Therefore, it is necessary to study the form of chemical elements and their behavior with respect to biological activity. Understanding the linkage between the biological activity and the behavior of chemical elements in seawater is the first step to explore oceanic environmental change including material cycles in sea water.

각막굴절수술(라식) 환자에 대한 경향성 분석

성아영,김찬수,이석주,조수현 대불대학교 2002 論文集 Vol.8 No.1

Now a days, LASIK(laser in situ keratomileusis) surgical operation is enforced widely by method that is used to correct ametropia such as near-sightedness, far-sightedness, astigmatism etc. This wishes to solve troublesome matter for glasses and contact lens wearer that reform a part of corneal stroma by laser after using microkeratome in which make corneal flap. This experiment present that refraction by auto-refractometer in point of time before and after a week to those who undergone LASIK surgical operation 30 patients. 60 eyes that become full corrected(spherical power : +0.50D∼-0.50D). By this research method, in point of time that examination has a week after operation because of refraction power changed by passage of time and classified by sex, age, occupation, and degree of myopia(low:-1.0D∼-3.0D, moderate: -3.0D∼-6.0D, high :more than -6.0D). As a result of this study LASIK surgery can solve uncomfortableness by wearing glasses or contact lens, but the result objectively doesn't meet satisfaction level though full correction had made.

단어생성시 기능적 자기공명영상을 통한 운동 언어중추의 국소화

정상욱,김주용,송인찬,이경민,이상건,장기현 대한신경과학회 1998 대한신경과학회지 Vol.16 No.5

조기진통의 진단과 처치

성문수,김현찬 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Prematurity and intra-uterine growth retardation(IUGR) and two main cause of low birth weight(LBW), a major contributor to infant mortality. The majority of LBW infants in developing countries is due to IUGR, while most LBW infants in industrialized countries are due to preform birth. The preform birth rate of almost 10% of birth has remained little changed for several decades, despite in changes in clinical practice and technology. Between 75~80% of those deliveries are due to either preform labor or preform prematurity of membranes. There is not yet complete understanding of the cause of preform labor. Preventive and treatment efforts aimed at single etiology have been unsuccessful to date, since the cause are multifactorial. Accurate diagnosis of preform labor remains a problematic issue. New techniques such as transvaginal cervical sonography and fetal fibronectin are increasingly important in diagnosis and intervention planning. Neither test can, at present, recommended for screening of general population since there is no effective intervention for a positive test. Future directions in research include development of new tocolytic agents and clarification of the best use of adjunctive therapies for lung maturity.

위 MALT 림프종에서 다발성 림프절 전이로 오인된 동시성 림프절 결핵 1예

김성은,김규종,김도현,송준영,문대성,장리라,유찬희,문원,박무인,박선자,김영옥 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

28세 남자가 내시경적 점막절제술을 통해 저등급 위MALT 림프종으로 진단되었다. 병기설정을 위해 18F-FDG PET 검사를 시행하였고 우측 쇄골상부, 우측상/하부 기관주위, AP window 부위에 강한 섭취가 관찰되어 전이성 림프절로 판단하였다. 그러나, 우측 쇄골상부 림프절에서 시행한 절제생검에서 만성육아종성염증소견이 관찰되었고 조직의 결핵 중합효소연쇄반응에서도 양성 반응을 보였다. 2개월간 항결핵제의 사용 후 시행한 추적 컴퓨터단층촬영 검사에서 림프절 크기의 감소를 보여 최종적으로 위 MALT 림프종에서 광범위 림프절 전이로 오인된 동시성 림프절 결핵으로 진단되었다. A 28-year-old man was diagnosed as gastric MALT lymphoma in diagnostic EMR (endoscopic mucosal resection). He subsequently underwent an 18F-FDG PET. 18F-FDG PET showed intense multifocal uptake in right supraclavicular, right upper and lower paratracheal, and AP window areas that was considered radiologically to represent widespread metastatic lymphadenopathy. Excisional biopsy of a supraclavicular lymph node, however, revealed chronic granulomatous lymphadenitis with a positive reaction of Tb-nested PCR. After antituberculosis treatment for 2 months, a follow-up CT scan showed complete resolution of the lesions. Intense 18F-FDG uptake could be due to an infectious process such as synchronous tuberculous lymphadenitis. Therefore, this could mimic a malignant condition such as lymphoma with extensive lymph node metastasis due to a false-positive finding, which may lead to a misdiagnosis.

재생굵은골재를 사용한 콘크리트의 동결융해 특성

성찬용,윤준노,김영익,임상혁,정덕현 충남대학교 농업과학연구소 2003 농업과학연구 Vol.30 No.2

이 연구는 플라이 애시를 결합재 중량의 20%, 재생굵은골재를 천연쇄석굵은 골재의 0%, 25%, 50%, 75%, 100%를 치환하여 압축강도와 동결융해 특성을 구명하였으며, 이 연구를 통해 얻어진 결과를 요약하면 다음과 같다. 1. 재령 28일의 압축강도는 모든 배합비와 W/B 35%에서 400㎏f/㎠이상으로 나타나 고강도콘크리트에 이용될 수 있을 것으로 생각된다. 2. 중량감소율은 동결융해 300사이클에서 1%미만으로 나타났고, 표면박리와 같은 현상은 나타나지 않았으며, 재생골재의 대체율이 증가할수록 감소율은 증가하였다. 3. 초음파진동속도는 동결융해 300사이클에서 19~24%정도의 감소율을 나타내었으며, 재생골재의 대체율이 증가할수록 감소율은 증가하는 경향을 나타내었다. 4. 상대동탄성계슈는 재생골재의 대체율에 따라 60~72%의 범위로 나타내었으며, 재생골재 대체율이 증가할수록 감소하는 경향을 나타내었다. 5. 내구성지수는 모든 배합에서 60이상을 나타내었으나, 재생골재 대체율이 100%일때는 급격히 떨어지는 경향을 나타내었다. 6. 재생굵은골재를 사용한 콘크리트의 압축강도, 중량감소율, 초음파진동속도, 상대동탄성계수, 내구성지수 시험결과를 볼 때, 시험에 사용한 재생굵은 골재는 고강도콘크리트에 사용이 가능할 것으로 판단된다. This study was performed to examine the freezing and thawing properties of the high strength concrete using recycled coarse aggregate. The recycled coarse aggregate was replaced by 0%, 25%, 50%, 75% and 100% of natural crushed aggregate. The compressive strength of the concrete used recycled coarse aggregate was shown in more than 400kgf/㎤ at the curing age 28 days. The weight loss ratio by freezing and thawing was shown in less than 1% at all mix type. The pulse velocity and relative dynamic modulus were decreased with increasing the freezing and thawing cycles. Also, durability factor for the freezing and thawing were decreased with increasing the content of recycled coarse aggregate. But, recycled concrete replaced with recycled coarse aggregate 100% was shown in more than 60 by durability factor in freezing and thawing of 300cycles Accordingly, these recycled coarse aggregate can be used for high strength concrete.

수종보익제가 면역세포의 조절 및 Apoptosis에 미치는 영향

한종현,강성용,정현우,오찬호,권진,은재순 대한본초학회 1997 大韓本草學會誌 Vol.12 No.1

The effects of several tonifying prescriptions on the apoptosis of transplanted L1210 cells and the regulation of immune cells in L1210-transplanted mice were studied. Sa-Mul-Tang(SMT), Sa-Kunja-Tang(SKT), Sipjeon-Daebo-Tang(SDT) accelerated the apoptosis of transplanted L1210 cells, and SMT and SKT reduced the mitochondrial transmembrane potential of transplanted L1210 cells. SMT promoted the proliferation of thymocytes and splenocytes in L1210-transplanted mice. Whereas SMT increased CD8+ T_c/T_S cell, Bojung-Ikki-Tang(BIT) decreased CD4+ T_H cell population in the thymocytes of L1210-transplanted mice. SMT and SKT increased the lucigenin chemiluminescence from peritoneal macrophage of L1210-transplanted mice. These results indicate that SMT and SKT have an inductive action of apoptosis of transplanted L1210 cells and peritoneal macrophage activation.

압축력을 받는 결함이 있는 구조물의 주파수 해석

姜贊泳,柳擇仁,朴鳳賢,李晟熙,韓秉基 弘益大學校 科學技術硏究所 1998 科學技術硏究論文集 Vol.9 No.1

Vibration analysis of through-the-width-split beams for predicting buckling load is investigated based on Euler-Bernoulli beam theory. In split region, each segment is considered as a solid beam. In this region, recurrence equations relating integration constants for adjacent interior regions are established by satisfying continuity conditions at junctions of interior regions. The results of present study are compared with those of experiment and their results give good agreement with each other. From the result, it was shown that local buckling phenomena could appear in fundamental mode, however, there exists load carrying capacity after this phenomena.