젊은 남자에게 발생한 통상성 간질성 폐렴과 동반된 폐암 1예

박종숙,이준혁,박성우,장안수,박춘식,박재성,백상현,고은석,신화균 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Usual interstitial pneumonia(UIP) is relatively rare disease of lung parenchyme under the age of 50. Lung cancer is reported to occur as a complication of UIP, but has not been reported in young age patient with UIP in Korea. A 35-year-old man was admitted to the hospital because of dyspnea, cough and mild fever. He had been suffered from dyspnea during 3 years. The dyspnea worsened recent 1 month ago. He had been treated with pneumonia at another hospital during 4 months before this admission. Chest radiographs and High resolution CT showed subpleural and basal dominant reticular opacities in both lung with no change until now. He was smoker and his occupation was car engine-man dealing with benzene. UIP is suspected by history and radiologic findings. Operation for open lung biopsy was performed to obtain lung specimen via video-assisted thoracoscopic surgery. Patient's pathologic examination showed UIP combined with adenocarcinoma in RLL superior segment and posterobasal segment and RLL lobectomy was done. After operation, the patient has been in cancer free condition so far. We report a case of UIP combined with lung cancer in young man with brief review of the literature.

원광의대 부속 제 2병원 신경정신과 환자에 대한 통계적 고찰

박민철,김종주,박남진,오상우,권혁일,권영숙,박종호 圓光大學校 醫科學硏究所 1986 圓光醫科學 Vol.2 No.2

We examined 1,856 patients who visited Won Kwang Neuropsychiatric hospital since July 11 of 1984(since the hospital opened) until June 11 of 1986. We researched diagnostic and other distributions of inpatients and outpatients. The study revealed as follows : 1. Of total patients males visited this hospital more than females as 52.7%. Most of them(67.1 %) resided in Iri, Iksan and Kimje. In the point of insurance, insured patients and uninsured patients except medicaids were 73 %. Males(60%) were more insured medically than females (55.4%). While insured patients relatively resided in urban area, but uninsured patients except medicaids did in rural area. 2. Of outpatients neurotic disorder was the most as 35.1%, secondly schizophrenic disorder and thirdly affective disorder, but of inpatients schizophrenic disorder was the most as 41.4%, secondly neurotic disorder thirdly affective disorder. 3. Alcohol abuse (98.2 %), paranoid disorder, convulsive disorder and child mental disorder were mostly found in males, but neurotic disorder (59 .6 %), affective disorder and other psychotic disorder were mostly found in females. 4. In unmarried ones schizophrenic disorder ( 43 .6 %), neurotic disorder, other psychotic disorder were common, but in married ones neurotic disorder (55.1 %), schizophrenic disorder, affective disorder were common. 5. On the distribution of age schizophrenic disorder was found the most in the twenties (28.4 %), next in the thirties and in the forties, but neurotic disorder was found the most in the thirties, next in the twenties and in the forties. 6. On the distribution of age at onset schizophrenic disorder develops mostly during the twenties (45.5 %), secondly during the teens and thirdly during the thirties, but neurotic disorder develops mostly during the thirties and the twenties (53.1 %). 7. On the duration of hospitalization 34.4% of the patients was hospitalized during less than 15 days, 22.0% during 60-90 days and 80.4% during less than 3 months. 8. In the result of treatment 41.2% of the patients was improved and 31.7% a little improved. In total 72.9% of the patients got helped therapeutically.

Transthyretin의 Glutathione 자동산화 촉진작용

박종근,정신,김재휴,김수한,강삼석,이제혁,안봉환 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.8

When reduced glutathione(GSH) was incubated at neutral pH and at 37°, its concentration decreased slowly with formation of oxidized glutathione(GSSG). Autooxidation of GSH was accelerated by Cu^(2+) and Hg^(2+), but not by other common mono-, di-, and tri-valent cations. Transthyretin was found to stimulate autooxidation of GSH in the presence or absence of Cu^(2+) and Hg^(2+). EDTA inhibited perfectly the autooxidation of GSH regardless of the presence of transthyretin. The stimulating activity of transthyretin was maximal at pH 7.0, declining progressively with increase or decrease of pH from 7.0. Sulfhydryl-blocking agents such as p-hydroxymercuribenzoic acid and Nethylmaleimide markedly inhibited the stimulating activity of transthyretin. Transthyretin stimulated autooxidation of other sulfhydryl compounds such as clithiothreitol and cysteine. However, it did not show a significant effect on autooxidation of sulfhydryl group of egg albumin and eye lens proteins. And transthyretin did not cause any oxidative change to thyroxine(T₄), 3, 5, 3Ltri iodo thyronine(T₃) and 3, 3: 5~triiodothpnine(rT₃) bound to it in the presence of GSH and Cu^(2+). The above results suggest that transthyretin may play a role in regulation of oxidized status of sulfhydryl groups in blood plasma and cerebrospinal fluid

Work Sampling 기법에 의한 철근콘크리트 작업의 작업분석

朴鐘奕,姜仁錫,李培浩 중앙대학교 기술과학연구소 1989 기술과학연구소 논문집 Vol.19 No.-

The present study was intended to find the method of improving productivity at construction work sites by employing and adapting the work measurment techniques. The study includes analysis of individuals worker's activities and work time distribution, and evaluation of work time-rates. The study adapted the work sampling method which is known to be simple and easy to use for the intended purposes and applied the method to the most typical construction operation of reinfored concrete structure works at an on-going building construction site. The operation comprises the work processes of form erection, steel bar installation and concrete placing. The study reveal that the actual working time rates, contributed to the effective work contents range from 22 to 42 percent of the total work time which are quite below the generally accepted standard of 55 percent. Assuming that the results of the study are typical in the construction industry of KOREA today, it is suggested that the improvement of productivity in construction work site requires better preplanning of work processes in such a way as to eliminate or reduce ineffective time contents to reasonable levels.

건설장비 활용방안에 관한 연구

朴鍾奕 瑞逸專門大學 1992 論文集 Vol.10 No.-

Construction equipment are of an variety in its type, size, and capability. Because of its prices being high, an appreciable effect on cost reduction is expected depending on the way of acquisition. It is therefore necessary to investigate all the modes of equipment acquisition before making a commitment. The different modes of acquisition and how they compare with each other economically constitute the object of this study.

정규화 반경벡터 함수에 기반한 2D-형태 정보검색

박혜진,이상학,이광재,장민혁,박종안 朝鮮大學校 電子情報通信硏究所 2003 電子情報通信硏究所論文誌 Vol.6 No.2

형태 정보는 컨텐츠 기반 하의 시각적 특징 중의 하나이며 영상 정보검색에서 광범위하게 사용된다. 본 연구에서는 물체 윤곽선의 반경 벡터함수를 이용한 스타형 및 비스타형 2D 형태인식을 위한 효과적인 알고리즘을 제안한다. 알고리즘에서 무게중심은 형태의 기준점이 되며 축의 중심으로부터 반경벡터는 주요 특징벡터가 된다. 이를 위한 코너 포인트는 노드로 표시되고, 정규화 거리는 중심점에서 노드까지의 상대적 거리비로 규정한다. 데이터베이스에서 유사 물체와 조회 물체 사이의 중심에서 코너 거리까지의 기하학적 거리가 형상 정합을 위한 유크리드 거리 값으로 정합평가에 이용된다.

마늘成分이 肝 Glutathione S-Transferase 및 Glutathione peroxidase 活性에 미치는 影響

朴鍾珉,李相日,金善業,許瑾,金碩煥,徐赫珪 嶺南大學校 環境問題硏究所 1985 環境硏究 Vol.5 No.2

Garlic (Allium sativum L.) is a widely distributed plant used in all parts of the world not only as a spice but also as a popular remedy for several thousand years Recent studies have shown that garlic components may regulate the many metabolism in liver. Therefore, the present work was undertaken to study the effect of garlicjuice, allicin fraction and heat-treated allicin fraction on the hepatic glutathione s-transferase and glutathione peroxidase which protect against toxic compound and lipid peroxide in liver. The results obtained were summarized as follows. By the treatment of garlic juice, glutathione s-transferase and glutathione peroxidase activity was increased in hepatic cytosolic fraction compare with control group. The enzyme activtiy is more increased by treatment with boiled garlic juice compared with fresh garlic juice in rats. The effect of allicin fraction and heat-treated allicin fraction on the hepatic glutathione s-transferase was observed that these components inhibited the enzyme activity in vitro, whereas the enzyme activity was strongly inhibited heat-treated allicin fraction than allicin fraction. These observation led us to conclude that the garlic components which are a stable substance in heat may regulate the hepatic glutathione s-transferase and glutathione peroxidase activity.

정신질환자 수용시설환자의 정신과적 입원치료 경험 유무에 따른 비교연구

박민철,오상우,권혁일,박남진,김종주 圓光大學校 醫科學硏究所 1986 圓光醫科學 Vol.2 No.2

We have visited the asylums in Chollapukdo for two months since March of 1985. We conducted a comparative study between the patients who has been previously hospitalized and who has not been hospitalized for psychiatric problems. We individually interviewed 489 patients using the interview schedule. The results are shown as follows: 1. The group who were young, single and highly educated have been more hospitalized than the groups who were old, married and little educated. However, no significant difference was made by sex and districts. 2. The group who lived alone or were deserted from the family has been rarely hospitalized. 3. The group, who has been entered the asylum by the family or who explained the reason as treatment, has been more hospitalized previously than the group entered by the others or who said that they came due to alcohol. 4. While the group who has been hospitalized showed tendency to accept having their psychiatric disorders, but the group who has not been hospitalized showed tendency to deny having their disorders. 5. The group who named their disorders psychoses or schizophrenia has been more hospitalized than the group who named them alcoholics. 6. The group hospitalized previously has been also treated in other ways besides psychiatric treatment, and chronic patients with the duration of more than three years has been relatively hospitalized previously. 7. While the group who has been previously hospitalized was relatively indicated for hospitalization, but the other group was not relatively indicated.

Al-Si합금용탕과 Al₂O₃의 젖음성에 관한 연구

朴昌宣,金鍾贊,朴相俊,權赫茂 忠南大學校 産業技術硏究所 1992 산업기술연구논문집 Vol.7 No.1

The purpose of this study is to obtain basic infotmation on the wettability of pure-Al/Al₂O₃, Al-alloy/Cu, Al-alloy/Ni and Al-12%Si/Al₂O₃systems, by using the Sessile drop method. The wettability of Al alloy-melt on Al₂O₃increases with increasing temperature from 750℃ to 850℃ for Al-12%Si-y% (Cu, Zn and Mg) (y:0∼2)/Al₂O₃system, the contact angle decreases with increasing Cu, Zn and Mg content. The wettability of Al alloy on Cu and Ni-palte is better than that on Al₂O₃-plate : this is attributed to the interfacial reaction between the Al aiioy and the metal substrate.

염색체이상에 관한 연구(611례 분석)

박종우,구선회,민혁기 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

From March, 1988 to October, 1993, we studied chromosomal analysis from peripheral blood to investigate chromosomal abnormalities in 611 patients showing multiple congenital anomaly, growth or mental retardation, repeated pregnancy losses, infertility, amenorrhea, pubertal failure, ambiguous genitalia, fetal anormaly, malignant disease and others. 82 chromosomal abnormalities were recognized as follows. 1. The rate of chromosomal abnormality is 13.2%. Among them, autosomal abnormality is 67% and sex chromosomal abnormality is 33%. 2. 22 cases of 47, XY,+21, 21 cases of 47, XX,+21, 3 cases of 46, XX, t(14;21)(qll;qll), and 1 case of 46, XX, t(15;21)(q11;q11) were found in Down syndrome. 3. 13 cases of 45, X, 4 cases of 46X, i(Xq), 2 cases of 46X, i(Xq)/45, X, 1 case of 45, X/46, Xr(X), and 1 case of 45, X/47, XXX were found in Turner syndrome. 4. 6 cases of Kleinfelter syndrome were found. 5. 4 cases of reciprocal translocation, 3 cases of Robertsonian translocation and 2 cases of ring chromosomes were found.