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      • GO-62 : Lower extremity edema in patients with endometrial cancer

        ( Myong Cheol Lim ),( Jeong Seon Lee ),( Jung Nam Joo ),( Sang Soo Seo ),( Sok Bom Kang ),( Sang Yoon Park ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-

        The objective of this study was to investigate clinical manifestations of lower extremity edema (LEE) in endometrial cancer Medical records for LEE and/or responses to the Gynecologic Cancer Lymphedema Questionnaire (GCLQ) were evaluated in 177 patients with endometrial cancer Patients had a median age of 53 years. Sixty-seven patients (37.9%) had past (9 patients, 13.4%) and/or current patient-reported LEE (58 patients, 86.6%). Symptoms reported on the GCLQ in over 20% of respondents were swelling, numbness, aching , and heaviness. GCLQ total symptoms score was significantly higher in patients with current LEE. Most of the LEE (43/67, 64.2%) developed within 12 months after surgery and LEE lasted more than 6 months in most patients (56/59, 94.9%) Prospective clinical trials are needed to know the clinical significance, impact on quality of life, and preventive strategy of LEE in patients with endometrial cancer

      • KCI등재
      • 工業敎育大學 敎育改善에 관한 硏究(Ⅲ)

        宋周鎬,李昌岬,洪元杓,孟琦錫,任洪彬,李廷玟,李載元,李來烈,權五憲,金振淳,李文洙 충남대학교 공업교육연구소 1982 論文集 Vol.5 No.1

        This paper aims at providing a concrete plan to improve technical and vocational teacher education in the College of Industrial Education of Chungnam National University. It is intended to propose a practical four-year regular and short-term course. Also, the estimated required facilities is included in this study as well as their management. The main conclusions and recommendations are summarized as follows; 1) The numbers of students enrollment should be reduced to 220 students which is the approximate number of future demand. 2) In order to offer to the students a broader education and to cope with the increase/decrease in demand of technical and vocational teacher within a specific field, the 8 department existing at the present (Department of Architecture Engineering Education, Civil Eng. Educ., Metallurgical Eng. Educ., Mechanical Eng. .Educ., Electrical Eng. Educ., Electronic Eng. Educ., Industrial Chemistry Educ. and Industrial Technology Educ.) would be combined into 5 (Department of Construction Engineering Education, Mechanical Eng. Educ., Electrical Eng. Educ., Industrial Chemistry Educ. and Industrial Technology Educ.). 3) The short-term course program is recommened to provide additional training and education to those candidates who already have experience in technical fields to meet an occasional demand. 4) It is necessary to add the Teaching Profession Section in the administrative organization of the College.

      • SCOPUSKCI등재

        추황배(Pyrus pyrifolia Nakai cv. Chuhwangbae) 과피로부터 1종의 Sterol과 3종의 배당체 화합물의 단리·동정

        이유건(Yu Geon Lee1),조정용(Jeong-Yong Cho),이현주(Hyun Joo Lee),이용현(Yong Hyun Lee),이상현(Sang-Hyun Lee),한태호(Tae-Ho Han),김월수(Wol-Soo Kim),박근형(Keun-Hyung Park),문제학(Jae-Hak Moon) 한국식품과학회 2013 한국식품과학회지 Vol.45 No.5

        본 연구에서는 배의 유용성 증명을 위한 일환으로 배의 화학성분을 분자수준에서 밝히고자 하였다. 이에 배 과피 MeOH 추출물을 용매분획하여 얻은 EtOAc-산성 분획과 EtOAc-중성분획을 대상으로 Sephadex LH-20, silica gel, 그리고 ODS colmn chromatography와 HPLC를 이용하여 정제 및 단리하였다. 그 결과, EtOAc-산성 분획과 EtOAc-중성 분획으로부터 각각 2종씩의 화합물을 단리하였다. 단리된 화합물 1-4는 1H- 및 13C-NMR 분석을 통하여 각각 (S)-(+)-2-cis-abscisic acid O-β-D-glucopyranosyl ester (화합물 1), 1-[4-O-β-D-glucopyranosyl]phenyl ethanone(piceoside, 화합물 2), β-sitosterol (화합물 3), 그리고 β-sitosteryl 3-O-β-D-glucopyranoside (화합물 4)로 동정되었다. 단리된 3종의 배당체 화합물(화합물 1, 2, 4)들은 본 연구에 의해 배로부터 처음 동정되었으며, 화합물 3은 추황배로부터 처음 동정되었다. 본 연구결과가 배 함유 성분연구는 물론 배의 기능성 해명 연구에도 추후 중요한 기초자료로 활용되길 기대한다. We isolated and identified antioxidants from acidic and neutral ethyl acetate fractions of the peel of pear (Pyrus pyrifolia N. cv. Chuhwangbae). We isolated 4 compounds from the methanol extract, by using 3 different types of column chromatography (Sephadex LH-20, silica gel, and octadecylsilane) and preparative HPLC. We identified the isolated compounds as (S)-(+)-2-cis-abscisic acid O-β-D-glucopyranosyl ester (compound 1), 1-[4-O-β-D-glucopyranosyl]phenyl ethanone (picroside, compound 2), β-sitosterol (compound 3), and β-sitosteryl 3-O-β-D-glucopyranoside (compound 4) by nuclear magnetic resonance analysis. We are the first to report the identification of compounds 1, 2, and 4 from pear.

      • KCI등재
      • 횡문근융해증과 급성 신부전 및 범발성 혈관내 응고장애를 동반한 열사병 1예

        최대은,박수진,권오경,이한규,이영모,이상주,나기량,이강욱,신영태 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

        Heat stroke is a life-threatening illness characterized by an elevated core body temperature that rises above 40% and central nervous system dysfunctions that results in delirium, convulsions, or coma. Heat stroke is subdivided into two forms, classic and exertional. Since strenuous exercise is one of the major exacerbating and precipitating factors, the incidence of exertional heat stroke is high among young adult, especially military personnel undergoing military training. Exertional heat stroke commonly causes rhabdomyolysis, lactic acidosis, acute renal failure, shock and pulmonary edema. We report a case of heat stroke with rhabdomyolysis, acute renal failure, disseminated intravascular coagulopathy(DIC) after strenuous exercise. A 18 year old man was admitted to the hospital because of loss of consciousness. He was a wrestler and he had tried to lose 6kg in weight by jogging and strenuous exercise on that summer day with hot temperature. The development of this illness was favoured by much clothes inappropriate for that environmental condition with a purpose to enhance sweating, and by restricted intake of water and food. On admission, the blood pressure was 80/50mmHg, and body temperature was 39.4℃ with stuporous mentality. Laboratory finding were as follows : in complete blood cell count, hemoglobin was 16.7g/dL and platelet count was 158,000/ mm³. In blood chemistry, AST 1061U/L, ALT 201U/L, BUN 30mg/dL, Cr 2.2mg/dL, LDH 941IU/L, CK 696IU/L were resulted. In arterial blood gas analysis, pH 7.39, pCO₂ 30mmHg pO₂ 86mmHg, HCO₃ 18.4mEq/L, O₂ saturation 96.7% were resulted. In urinalysis, specific gravity 1.025, protein 3+, erythrocyte 2+ were resulted. In brain imaging study, brain CT finding was normal. After appropriate treatments with rapid cooling, hydration and supportive care, he improved with alert mental status. On 2nd hospital day, in laboratory result, thrombocytopenia and coagulopathy were appeared and renal insufficiency was aggravated. So he was treated with platelet concentrate and fresh frosen plasma for DIC, and enough hydration for appropriate urine volume preservation. After all, On 22nd hospital day, he fully recovered and discharged. Nowadays, with followed for some duration, he is wellbeing with no complications.

      • SCOPUSKCI등재

        Genetic Characterization of Haemagglutinin 1 Domain of Influenza B Viruses Isolated in Korea during $1988{\sim}1999$

        Shin, Gu-Choul,Na, Byoung-Kuk,Lee, Joo-Yeon,Ahn, Jung-Bae,Park, Jong-Won,Lee, Jin-Soo,Kim, Jee-Hee,Kim, Woo-Joo,Kang, Chun The Korean Society for Microbiology 2003 Journal of Bacteriology and Virology Vol.33 No.4

        Although Korean influenza virus isolates have been genetically associated with the vaccine strains of the corresponding year, influenza B viruses have prevailed almost every year in Korea during the past decades. We have 'analyzed the genetic characteristics and evolutionary patterns of the haemagglutinin (HA) 1 domains of influenza B viruses isolated during 1988-1999 using direct RT-PCR and sequencing. Phylogenetic analysis of influenza B viruses isolated in Korea indicated that antigenically and genetically distinguishable strains of the lineage II and lineage III variants had been cocirculated. Variants prevailed in early 1990s are represented in 1996/97 and 1998/99 and some different variants have been co circulated geographically and prevailed concurrently in Korea. All HA1s of Korean isolates have amino acid substitutions mainly in the region between position 124 and 310, which was previously proposed an immunodominant region. Insertion-deletion patterns of the HA gene revealed that Korean influenza B viruses were evolved from Lee40 with different manner between lineage II and III viruses. Lineage III viruses were also divided into two groups as conserved group and inserted group, in relation to Lee40. But lineage II viruses had evolved with directional pattern. Antigenic index proposed that influenza B isolates prevailed since 1996/97 seasons might had emerged from the antigenic variants of a Seo1697-like virus and that new variants might appear from the lineage II viruses resulting in persistent prevalence in Korea.

      • 종합 합성어와 어근 합성어의 특성

        이주희,여도수 공주영상정보대학 1998 논문집 Vol.5 No.-

        Roeper & Siegil(1978)은 -er, -ing, -en 등의 접미사를 갖는 것을 종합 합성어로 취급하고, 그 외의 접미사를 갖는 것을 어근 합성어로 취급한다. Selkirk는 어근 합성어와 종합 합성어를 모두 동일한 규칙에 의해 도출하며, 단지 논항구조의 만족여부로 이들을 구별하였다. Selkirk는 모양에 관계없이 논항구조를 만족시키는 것은 종합 합성어로 취급한다. Fabb은 모양에 상관없이 동사부의 원칙을 지키면 동사부에서 도출되는 종합 합성어, 통사부의 원칙을 위배하면 어휘부에서 도출되는 어근 합성어로 구분된다. 따라서 Fabb은 동일한 모양의 접사라도 경우에 따라서 동사부와 어휘부에서 나뉘어 첨가된다. 즉 종합 합성어는 통사부에서 도출되고, 어근 합성어는 어휘부에서 도출된다는 것이다. 그러나 이는, 어형성 과정 가운데서 통사적 원칙으로 설명하기 편한 것은 통사부에 남겨두고, 통사적 원칙으로 설명하기 어려운 것만 어휘부의 몫으로 돌리자는 것이자 마찬가지이다. 단어가 형성되고 나면 일단 통사부의 규칙을 모두 적용해 본 후 통사부의 규칙이 적용된다면, 통사부에 남겨두고, 통사부의 규칙이 적용되지 않으면, 어휘부로 돌리는 식의 복잡한 과정을 거쳐야 한다. 따라서 Fabb의 주장도 맞지 않는다. 결국 어형성은 어휘부에서 이루어져야 한다. Marchand(1969:80)은 행위자 명사가 dealer, woker처럼 독립해 사될 수 있는 경우를 종합 합성어로 보고, Allen(1978:161)도 비슷한 견해인데 반해, Roeper & Siegel(1978:218)은 행위자 명사가 독립하여 사용될 수 있는 경우를 어근 합성어의 특성이라고 생각한다. 따라서 Marchand(1969), Allen(1978)와 Roeper & Siegel(1978), Fabb(1984)은 합성어의 핵심어인 행위자 명사의 독립 가능성에 있어서는 서롤 상반된 견해를 나타낸다.

      • KCI등재후보

        컴퓨터 부문에서의 품질조정 가격지수

        이영수,조주현 한국산업조직학회 2003 産業組織硏究 Vol.11 No.2

        본 연구는 기술개발 속도가 현저하게 이루어지고 있는 컴퓨터 및 주변기기(모니터, 프린터)를 대상으로 품질조정 가격지수를 산정하였다. 또한, 이러한 품질조정 가격지수가 생산자물가지수를 포함하여 ICT부문의 생산자물가지수에 미치는 효과를 살펴보았다. 품질조정 가격지수를 구하기 위해 헤도닉방법을 이용하였으며, 추정방법으로는 더미변수를 이용하여 추정하였다. 실증분석 결과를 요약하면 다음과 같다. 첫째, 컴퓨터 및 주변기기의 품질조정 가격하락 효과 분석에서 컴퓨터 본체의 가격지수는 1990년-2002년 동안 연평균 26.4%p 추가적으로 하락하는 것으로 나타났다. 모니터와 프린터의 경우 각각 연평균 15%p, 11.5%p의 추가적인 가격하락 효과가 있는 것으로 나타났다. 둘째, 컴퓨터 및 주변기기의 물가지수는 품질향상으로 1991-2002년 동안 연평균 11.54%p의 추가적인 가격하락을 보였다. 이러한 컴퓨터 본체, 모니터 및 프린터의 품질개선 효과로 사무회계용 기기의 물가지수는 추가적으로 연평균 10.83%p 하락했으며, ICT부문의 물가지수 역시 연평균 1.542%p 추가적인 하락이 나타났다. 또한 이러한 품질개선에 따른 추가적인 물가하락은 생산자물가지수에도 영향을 주어 1991년-2002년 기간동안 연평균 1.495%p의 추가적인 물가하락을 보였다. 셋째 본 연구와 이영수 외(2002)의 연구를 비교하여 볼 때 컴퓨터 본체의 품질조정으로 인한 가격하락 효과 추이는 비슷하게 나타나고 있어 본 연구의 결과가 안정적이고 강건한(robust)한 추정결과임을 알 수 있었다. In this paper, we attempt to calculate a quality-adjusted price indexes for the personal computer and peripheral devices(monitor, printer) that have experienced rapid technological and market developments. Moreover we analyze the PPI of ICT including the quality-adjusted price index. To calculate a quality-adjusted price index we utilize the framework of the hedonic approach and dummy variable estimation method. The conclusions which can be drawn from our empirical study are these: 1) personal computer, monitor, printer price indexes decline additionally at about 26.4%p, 15%p, 11.5%p respectively over the 1990∼2002 time period 2) price indexes in office accounting machinery and ICT decline additionally 10.83%p, 11.54%p respectively 3) PPI declines additionally 1.542%p per year considering the quality changes 4) comparing the previous work we know that our empirical results are stable and robust.

      • KCI등재

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